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Items: 28

1.

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.

Monovich L, Koch KA, Burgis R, Osimboni E, Mann T, Wall D, Gao J, Feng Y, Vega RB, Turner BA, Hood DB, Law A, Papst PJ, Koditek D, Chapo JA, Reid BG, Melvin LS, Pagratis NC, McKinsey TA.

Biochim Biophys Acta. 2009 May;1789(5):422-31. doi: 10.1016/j.bbagrm.2009.04.001. Epub 2009 May 3.

PMID:
19414071
2.

Disposition and metabolism of tenidap in the rat.

Fouda HG, Avery MJ, Dalvie D, Falkner FC, Melvin LS, Ronfeld RA.

Drug Metab Dispos. 1997 Feb;25(2):140-8.

3.

The conformational properties of the highly selective cannabinoid receptor ligand CP-55,940.

Xie XQ, Melvin LS, Makriyannis A.

J Biol Chem. 1996 May 3;271(18):10640-7.

4.

Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity.

Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC.

Drug Des Discov. 1995 Nov;13(2):155-66.

PMID:
8872458
5.

(+)-1-(3S,4R)-[3-(4-phenylbenzyl)-4-hydroxychroman-7-yl]cyclopentane carboxylic acid, a highly potent, selective leukotriene B4 antagonist with oral activity in the murine collagen-induced arthritis model.

Koch K, Melvin LS Jr, Reiter LA, Biggers MS, Showell HJ, Griffiths RJ, Pettipher ER, Cheng JB, Milici AJ, Breslow R, et al.

J Med Chem. 1994 Sep 30;37(20):3197-9. No abstract available.

PMID:
7932545
6.

Conformational analysis of the prototype nonclassical cannabinoid CP-47,497, using 2D NMR and computer molecular modeling.

Xie XQ, Yang DP, Melvin LS, Makriyannis A.

J Med Chem. 1994 May 13;37(10):1418-26.

PMID:
8182700
7.

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs.

Melvin LS, Milne GM, Johnson MR, Subramaniam B, Wilken GH, Howlett AC.

Mol Pharmacol. 1993 Nov;44(5):1008-15.

PMID:
8246904
8.

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

Compton DR, Rice KC, De Costa BR, Razdan RK, Melvin LS, Johnson MR, Martin BR.

J Pharmacol Exp Ther. 1993 Apr;265(1):218-26.

PMID:
8474008
9.

The cannabinoid receptor-pharmacologic identification, anatomical localization and cloning.

Johnson MR, Rice KC, Howlett A, Melvin LS, Herkenham M.

NIDA Res Monogr. 1992;119:86-90. Review. No abstract available.

PMID:
1435988
10.

Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents.

Compton DR, Johnson MR, Melvin LS, Martin BR.

J Pharmacol Exp Ther. 1992 Jan;260(1):201-9.

PMID:
1309872
11.

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs.

Martin BR, Compton DR, Thomas BF, Prescott WR, Little PJ, Razdan RK, Johnson MR, Melvin LS, Mechoulam R, Ward SJ.

Pharmacol Biochem Behav. 1991 Nov;40(3):471-8.

PMID:
1666911
12.

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study.

Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR, Rice KC.

J Neurosci. 1991 Feb;11(2):563-83.

13.

Synthetic and biological studies of potential affinity ligands for the cannabinoid receptor based on CP-55, 244.

Richardson S, Mirasadeghi S, Lynn A, Johnson MR, Melvin LS, Herkenham M, Rice KC.

NIDA Res Monogr. 1990;105:140-6. Review. No abstract available.

PMID:
1875994
14.

The cannabinoid receptor: biochemical, anatomical and behavioral characterization.

Howlett AC, Bidaut-Russell M, Devane WA, Melvin LS, Johnson MR, Herkenham M.

Trends Neurosci. 1990 Oct;13(10):420-3. Review.

PMID:
1700516
15.

Cannabinoid receptor localization in brain.

Herkenham M, Lynn AB, Little MD, Johnson MR, Melvin LS, de Costa BR, Rice KC.

Proc Natl Acad Sci U S A. 1990 Mar;87(5):1932-6.

16.

Classical and nonclassical cannabinoids: mechanism of action--brain binding.

Howlett AC, Johnson MR, Melvin LS.

NIDA Res Monogr. 1990;96:100-11. Review. No abstract available.

PMID:
2172821
17.

Progress toward the synthesis of potential affinity ligands for the analgesic cannabinoid receptor based on CP-55,244.

Richardson S, Herkenham M, Mirsadeghi S, Johnson MR, Melvin LS, Rice KC.

NIDA Res Monogr. 1989;95:532-3. No abstract available.

PMID:
2641050
18.

Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.

Little PJ, Compton DR, Johnson MR, Melvin LS, Martin BR.

J Pharmacol Exp Ther. 1988 Dec;247(3):1046-51.

PMID:
2849657
19.

Determination and characterization of a cannabinoid receptor in rat brain.

Devane WA, Dysarz FA 3rd, Johnson MR, Melvin LS, Howlett AC.

Mol Pharmacol. 1988 Nov;34(5):605-13.

PMID:
2848184
20.

Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model.

Howlett AC, Johnson MR, Melvin LS, Milne GM.

Mol Pharmacol. 1988 Mar;33(3):297-302.

PMID:
3352594
21.

Structure-activity relationships of tricyclic and nonclassical bicyclic cannabinoids.

Melvin LS, Johnson MR.

NIDA Res Monogr. 1987;79:31-47. Review. No abstract available.

PMID:
3125479
22.

Enhancement of brain [3H]flunitrazepam binding and analgesic activity of synthetic cannabimimetics.

Koe BK, Milne GM, Weissman A, Johnson MR, Melvin LS.

Eur J Pharmacol. 1985 Feb 26;109(2):201-12.

PMID:
2986995
23.

A cannabinoid derived prototypical analgesic.

Melvin LS, Johnson MR, Harbert CA, Milne GM, Weissman A.

J Med Chem. 1984 Jan;27(1):67-71.

PMID:
6690685
24.

Cannabimimetic activity from CP-47,497, a derivative of 3-phenylcyclohexanol.

Weissman A, Milne GM, Melvin LS Jr.

J Pharmacol Exp Ther. 1982 Nov;223(2):516-23.

PMID:
6290642
25.

Prototype cannabinoid analgetics, prostaglandins and opiates--a search for points of mechanistic interaction.

Johnson MR, Melvin LS, Milne GM.

Life Sci. 1982 Oct 18-25;31(16-17):1703-6. No abstract available.

PMID:
6296573
26.

Selective and potent analgetics derived from cannabinoids.

Johnson MR, Melvin LS, Althuis TH, Bindra JS, Harbert CA, Milne GM, Weissman A.

J Clin Pharmacol. 1981 Aug-Sep;21(S1):271S-282S.

PMID:
6271833
27.

Potent analgetics derived from 9-nor-9 beta-hydroxyhexahydrocannabinol.

Johnson MR, Althuis TH, Bindra JS, Harbert CA, Melvin LS, Milne GM.

NIDA Res Monogr. 1981 Feb;34:68-74.

PMID:
6111753
28.

Letter: Synthesis of novel macrocyclic lactones in the prostaglandin and polyether antibiotic series.

Cory EJ, Nicolaou KC, Melvin LS Jr.

J Am Chem Soc. 1975 Feb 5;97(3):653-4. No abstract available.

PMID:
1133366

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