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Items: 1 to 50 of 325

1.

Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation.

Liu X, Abraham JM, Cheng Y, Wang Z, Wang Z, Zhang G, Ashktorab H, Smoot DT, Cole RN, Boronina TN, DeVine LR, Talbot CC Jr, Liu Z, Meltzer SJ.

Mol Ther Nucleic Acids. 2018 Sep 22;13:312-321. doi: 10.1016/j.omtn.2018.09.010. [Epub ahead of print]

2.

Modeling Wnt signaling by CRISPR-Cas9 genome editing recapitulates neoplasia in human Barrett epithelial organoids.

Liu X, Cheng Y, Abraham JM, Wang Z, Wang Z, Ke X, Yan R, Shin EJ, Ngamruengphong S, Khashab MA, Zhang G, McNamara G, Ewald AJ, Lin D, Liu Z, Meltzer SJ.

Cancer Lett. 2018 Nov 1;436:109-118. doi: 10.1016/j.canlet.2018.08.017. Epub 2018 Aug 23.

PMID:
30144514
3.

Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression.

Zhang X, Peng Y, Huang Y, Deng S, Feng X, Hou G, Lin H, Wang J, Yan R, Zhao Y, Fan X, Meltzer SJ, Li S, Jin Z.

Cell Death Dis. 2018 Jul 13;9(7):778. doi: 10.1038/s41419-018-0785-5.

4.

Research Gaps in Gestational Diabetes Mellitus: Executive Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Wexler DJ, Powe CE, Barbour LA, Buchanan T, Coustan DR, Corcoy R, Damm P, Dunne F, Feig DS, Ferrara A, Harper LM, Landon MB, Meltzer SJ, Metzger BE, Roeder H, Rowan JA, Sacks DA, Simmons D, Umans JG, Catalano PM.

Obstet Gynecol. 2018 Aug;132(2):496-505. doi: 10.1097/AOG.0000000000002726.

PMID:
29995731
5.

Health behaviour changes in partners of women with recent gestational diabetes: a phase IIa trial.

Brazeau AS, Meltzer SJ, Pace R, Garfield N, Godbout A, Meissner L, Rahme E, Da Costa D, Dasgupta K.

BMC Public Health. 2018 May 2;18(1):575. doi: 10.1186/s12889-018-5490-x.

6.

Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma.

Xie JJ, Jiang YY, Jiang Y, Li CQ, Lim MC, An O, Mayakonda A, Ding LW, Long L, Sun C, Lin LH, Chen L, Wu JY, Wu ZY, Cao Q, Fang WK, Yang W, Soukiasian H, Meltzer SJ, Yang H, Fullwood M, Xu LY, Li EM, Lin DC, Koeffler HP.

Gastroenterology. 2018 Jun;154(8):2137-2151.e1. doi: 10.1053/j.gastro.2018.02.018. Epub 2018 Feb 15.

PMID:
29454790
7.

SMG-1 inhibition by miR-192/-215 causes epithelial-mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling.

Zhang X, Peng Y, Huang Y, Yang M, Yan R, Zhao Y, Cheng Y, Liu X, Deng S, Feng X, Lin H, Yu H, Chen S, Zhao Z, Li S, Li K, Wang L, Wei Y, He Z, Fan X, Meltzer SJ, Li S, Jin Z.

Cancer Med. 2018 Jan;7(1):146-156. doi: 10.1002/cam4.1237. Epub 2017 Dec 13.

8.

Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids.

Ke X, Yan R, Sun Z, Cheng Y, Meltzer A, Lu N, Shu X, Wang Z, Huang B, Liu X, Wang Z, Song JH, Ng CK, Ibrahim S, Abraham JM, Shin EJ, He S, Meltzer SJ.

Neoplasia. 2017 Nov;19(11):941-949. doi: 10.1016/j.neo.2017.06.007. Epub 2017 Sep 29.

9.

Choosing the Best Therapy for Your Patients in Today's Diabetes World.

Meltzer SJ, Yale JF.

Can J Diabetes. 2017 Oct;41(5):465-466. doi: 10.1016/j.jcjd.2017.08.002. Epub 2017 Aug 23. No abstract available.

PMID:
28843473
10.

Determination of absolute expression profiles using multiplexed miRNA analysis.

Song Y, Kilburn D, Song JH, Cheng Y, Saeui CT, Cheung DG, Croce CM, Yarema KJ, Meltzer SJ, Liu KJ, Wang TH.

PLoS One. 2017 Jul 13;12(7):e0180988. doi: 10.1371/journal.pone.0180988. eCollection 2017.

11.

RNA sequencing of esophageal adenocarcinomas identifies novel fusion transcripts, including NPC1-MELK, arising from a complex chromosomal rearrangement.

Wang Z, Cheng Y, Abraham JM, Yan R, Liu X, Chen W, Ibrahim S, Schroth GP, Ke X, He Y, Meltzer SJ.

Cancer. 2017 Oct 15;123(20):3916-3924. doi: 10.1002/cncr.30837. Epub 2017 Jun 22.

12.

Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Eluri S, Parian AM, Limketkai BN, Ha CY, Brant SR, Dudley-Brown S, Efron JE, Fang SG, Gearhart SL, Marohn MR, Meltzer SJ, Bashar S, Truta B, Montgomery EA, Lazarev MG.

Dig Dis Sci. 2017 Dec;62(12):3586-3593. doi: 10.1007/s10620-017-4652-5. Epub 2017 Jun 19.

PMID:
28631086
13.

Long Noncoding RNAs in the Pathogenesis of Barrett's Esophagus and Esophageal Carcinoma.

Abraham JM, Meltzer SJ.

Gastroenterology. 2017 Jul;153(1):27-34. doi: 10.1053/j.gastro.2017.04.046. Epub 2017 May 18. Review.

14.

Gastric Cancer in the Era of Precision Medicine.

Liu X, Meltzer SJ.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;3(3):348-358. doi: 10.1016/j.jcmgh.2017.02.003. eCollection 2017 May. Review.

15.

Radiofrequency Ablation of Barrett's Esophagus Reduces Esophageal Adenocarcinoma Incidence and Mortality in a Comparative Modeling Analysis.

Kroep S, Heberle CR, Curtius K, Kong CY, Lansdorp-Vogelaar I, Ali A, Wolf WA, Shaheen NJ, Spechler SJ, Rubenstein JH, Nishioka NS, Meltzer SJ, Hazelton WD, van Ballegooijen M, Tramontano AC, Gazelle GS, Luebeck EG, Inadomi JM, Hur C.

Clin Gastroenterol Hepatol. 2017 Sep;15(9):1471-1474. doi: 10.1016/j.cgh.2016.12.034. Epub 2017 Jan 12. No abstract available.

16.

The novel fusion transcript NR5A2-KLHL29FT is generated by an insertion at the KLHL29 locus.

Sun Z, Ke X, Salzberg SL, Kim D, Antonescu V, Cheng Y, Huang B, Song JH, Abraham JM, Ibrahim S, Tian H, Meltzer SJ.

Cancer. 2017 May 1;123(9):1507-1515. doi: 10.1002/cncr.30510. Epub 2017 Jan 12.

17.

Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett's Esophagus: A Systematic Review and Meta-Analysis.

Hu Q, Sun TT, Hong J, Fang JY, Xiong H, Meltzer SJ.

PLoS One. 2017 Jan 10;12(1):e0169691. doi: 10.1371/journal.pone.0169691. eCollection 2017. Review.

18.

MiRNA-194 activates the Wnt/β-catenin signaling pathway in gastric cancer by targeting the negative Wnt regulator, SUFU.

Peng Y, Zhang X, Ma Q, Yan R, Qin Y, Zhao Y, Cheng Y, Yang M, Wang Q, Feng X, Huang Y, Huang W, Zhao Z, Wang L, Wei Y, He Z, Fan X, Li S, Jin Z, Meltzer SJ.

Cancer Lett. 2017 Jan 28;385:117-127. doi: 10.1016/j.canlet.2016.10.035. Epub 2016 Oct 31.

PMID:
27810403
19.

Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response.

Yan R, Zhu K, Dang C, Lan K, Wang H, Yuan D, Chen W, Meltzer SJ, Li K.

Oncotarget. 2016 Jun 21;7(25):38750-38761. doi: 10.18632/oncotarget.9606.

20.

Leaky transporters and sphincters in Barrett's oesophagus?

Meltzer SJ.

Lancet Oncol. 2016 Oct;17(10):1336-1337. doi: 10.1016/S1470-2045(16)30365-5. Epub 2016 Aug 12. No abstract available.

21.

Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model.

Li L, Piontek K, Ishida M, Fausther M, Dranoff JA, Fu R, Mezey E, Gould SJ, Fordjour FK, Meltzer SJ, Sirica AE, Selaru FM.

Hepatology. 2017 Feb;65(2):501-514. doi: 10.1002/hep.28735. Epub 2016 Aug 29.

22.

TNFAIP8 overexpression: a potential predictor of lymphatic metastatic recurrence in pN0 esophageal squamous cell carcinoma after Ivor Lewis esophagectomy.

Sun Z, Liu X, Song JH, Cheng Y, Liu Y, Jia Y, Meltzer SJ, Wang Z.

Tumour Biol. 2016 Aug;37(8):10923-34. doi: 10.1007/s13277-016-4978-1. Epub 2016 Feb 17.

PMID:
26886285
23.

Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression.

Huang B, Song JH, Cheng Y, Abraham JM, Ibrahim S, Sun Z, Ke X, Meltzer SJ.

Oncogene. 2016 Sep 15;35(37):4927-36. doi: 10.1038/onc.2016.25. Epub 2016 Feb 15.

24.

Whole-Exome Sequencing Analyses of Inflammatory Bowel Disease-Associated Colorectal Cancers.

Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, Harris CC, Papadopoulos N.

Gastroenterology. 2016 Apr;150(4):931-43. doi: 10.1053/j.gastro.2015.12.036. Epub 2016 Jan 5.

25.

Integrated miRNA profiling and bioinformatics analyses reveal potential causative miRNAs in gastric adenocarcinoma.

Zhang X, Peng Y, Jin Z, Huang W, Cheng Y, Liu Y, Feng X, Yang M, Huang Y, Zhao Z, Wang L, Wei Y, Fan X, Zheng D, Meltzer SJ.

Oncotarget. 2015 Oct 20;6(32):32878-89. doi: 10.18632/oncotarget.5419.

26.

TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.

Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S.

Oncotarget. 2015 Oct 20;6(32):32610-21. doi: 10.18632/oncotarget.5362.

27.

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma.

Doucet-O'Hare TT, Rodić N, Sharma R, Darbari I, Abril G, Choi JA, Young Ahn J, Cheng Y, Anders RA, Burns KH, Meltzer SJ, Kazazian HH Jr.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):E4894-900. doi: 10.1073/pnas.1502474112. Epub 2015 Aug 17. Erratum in: Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):E104.

28.

Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma.

Tang X, Wang Y, Fan Z, Ji G, Wang M, Lin J, Huang S, Meltzer SJ.

Lab Invest. 2016 Feb;96(2):197-205. doi: 10.1038/labinvest.2015.86. Epub 2015 Aug 3. Review.

29.

Addendum: BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia.

Bennett C, Moayyedi P, Corley DA, DeCaestecker J, Falck-Ytter Y, Falk G, Vakil N, Sanders S, Vieth M, Inadomi J, Aldulaimi D, Ho KY, Odze R, Meltzer SJ, Quigley E, Gittens S, Watson P, Zaninotto G, Iyer PG, Alexandre L, Ang Y, Callaghan J, Harrison R, Singh R, Bhandari P, Bisschops R, Geramizadeh B, Kaye P, Krishnadath S, Brian Fennerty M, Manner H, Nason KS, Pech O, Konda V, Ragunath K, Rahman I, Romero Y, Sampliner R, Siersema PD, Tack J, Tham TC, Trudgill N, Weinberg DS, Wang J, Wang K, Wong JY, Attwood S, Malfertheiner P, MacDonald D, Barr H, Ferguson MK, Jankowski J; BOB CAT Consortium.

Am J Gastroenterol. 2015 Jun;110(6):943. doi: 10.1038/ajg.2015.151. No abstract available.

PMID:
26052782
30.

Phosphorus-32, a clinically available drug, inhibits cancer growth by inducing DNA double-strand breakage.

Cheng Y, Kiess AP, Herman JM, Pomper MG, Meltzer SJ, Abraham JM.

PLoS One. 2015 Jun 1;10(6):e0128152. doi: 10.1371/journal.pone.0128152. eCollection 2015.

31.

BOB CAT: A Large-Scale Review and Delphi Consensus for Management of Barrett's Esophagus With No Dysplasia, Indefinite for, or Low-Grade Dysplasia.

Bennett C, Moayyedi P, Corley DA, DeCaestecker J, Falck-Ytter Y, Falk G, Vakil N, Sanders S, Vieth M, Inadomi J, Aldulaimi D, Ho KY, Odze R, Meltzer SJ, Quigley E, Gittens S, Watson P, Zaninotto G, Iyer PG, Alexandre L, Ang Y, Callaghan J, Harrison R, Singh R, Bhandari P, Bisschops R, Geramizadeh B, Kaye P, Krishnadath S, Fennerty MB, Manner H, Nason KS, Pech O, Konda V, Ragunath K, Rahman I, Romero Y, Sampliner R, Siersema PD, Tack J, Tham TC, Trudgill N, Weinberg DS, Wang J, Wang K, Wong JY, Attwood S, Malfertheiner P, MacDonald D, Barr H, Ferguson MK, Jankowski J; BOB CAT Consortium.

Am J Gastroenterol. 2015 May;110(5):662-82; quiz 683. doi: 10.1038/ajg.2015.55. Epub 2015 Apr 14. Review. Erratum in: Am J Gastroenterol. 2015 Jun;110(6):943.

32.

Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent.

Ning Z, Zhu H, Li F, Liu Q, Liu G, Tan T, Zhang B, Chen S, Li G, Huang D, Meltzer SJ, Zhang H.

Genes Cancer. 2014 Nov;5(11-12):436-44.

33.

Differential methylation of the promoter and first exon of the RASSF1A gene in hepatocarcinogenesis.

Jain S, Xie L, Boldbaatar B, Lin SY, Hamilton JP, Meltzer SJ, Chen SH, Hu CT, Block TM, Song W, Su YH.

Hepatol Res. 2015 Nov;45(11):1110-23. doi: 10.1111/hepr.12449. Epub 2014 Dec 9.

34.

Unhealthy lifestyles and gestational diabetes.

Meltzer SJ.

BMJ. 2014 Sep 30;349:g5549. doi: 10.1136/bmj.g5549. No abstract available.

PMID:
25270049
35.

Group-based activities with on-site childcare and online support improve glucose tolerance in women within 5 years of gestational diabetes pregnancy.

Brazeau AS, Leong A, Meltzer SJ, Cruz R, DaCosta D, Hendrickson-Nelson M, Joseph L, Dasgupta K; MoMM study group.

Cardiovasc Diabetol. 2014 Jun 30;13:104. doi: 10.1186/1475-2840-13-104.

36.

Temporal evolution in caveolin 1 methylation levels during human esophageal carcinogenesis.

Jin Z, Wang L, Cao Z, Cheng Y, Gao Y, Feng X, Chen S, Yu H, Wu W, Zhao Z, Dong M, Zhang X, Liu J, Fan X, Mori Y, Meltzer SJ.

BMC Cancer. 2014 May 20;14:345. doi: 10.1186/1471-2407-14-345.

37.

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials.

Michailidi C, Soudry E, Brait M, Maldonado L, Jaffe A, Ili-Gangas C, Brebi-Mieville P, Perez J, Kim MS, Zhong X, Yang Q, Valle B, Meltzer SJ, Torbenson M, Esteller M, Sidransky D, Guerrero-Preston R.

Gastroenterol Res Pract. 2014;2014:597164. doi: 10.1155/2014/597164. Epub 2014 Apr 17.

38.

Strategies for implementing the WHO diagnostic criteria and classification of hyperglycaemia first detected in pregnancy.

Colagiuri S, Falavigna M, Agarwal MM, Boulvain M, Coetzee E, Hod M, Meltzer SJ, Metzger B, Omori Y, Rasa I, Schmidt MI, Seshiah V, Simmons D, Sobngwi E, Torloni MR, Yang HX.

Diabetes Res Clin Pract. 2014 Mar;103(3):364-72. doi: 10.1016/j.diabres.2014.02.012. Epub 2014 Feb 25.

PMID:
24731475
39.

In-hospital diabetes management.

Cheng AY, Houlden RL, Meltzer SJ.

Can J Diabetes. 2014 Apr;38(2):71-2. doi: 10.1016/j.jcjd.2014.02.003. No abstract available.

PMID:
24690498
40.

Human bile contains microRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis.

Li L, Masica D, Ishida M, Tomuleasa C, Umegaki S, Kalloo AN, Georgiades C, Singh VK, Khashab M, Amateau S, Li Z, Okolo P, Lennon AM, Saxena P, Geschwind JF, Schlachter T, Hong K, Pawlik TM, Canto M, Law J, Sharaiha R, Weiss CR, Thuluvath P, Goggins M, Shin EJ, Peng H, Kumbhari V, Hutfless S, Zhou L, Mezey E, Meltzer SJ, Karchin R, Selaru FM.

Hepatology. 2014 Sep;60(3):896-907. doi: 10.1002/hep.27050. Epub 2014 Jul 25. Erratum in: Hepatology. 2014 Dec;60(6):2135.

41.

Effects of vitamin D3 stimulation of thioredoxin-interacting protein in hepatocellular carcinoma.

Hamilton JP, Potter JJ, Koganti L, Meltzer SJ, Mezey E.

Hepatol Res. 2014 Dec;44(13):1357-66. doi: 10.1111/hepr.12302. Epub 2014 Mar 25.

42.

Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer.

Jin Z, Feng X, Jian Q, Cheng Y, Gao Y, Zhang X, Wang L, Zhang Y, Huang W, Fan X, Chen S, Yu H, Zhao Z, Dong M, Liu J, Mori Y, Meltzer SJ.

Anticancer Res. 2013 Nov;33(11):5199-203.

PMID:
24222170
43.

MAL hypermethylation is a tissue-specific event that correlates with MAL mRNA expression in esophageal carcinoma.

Jin Z, Wang L, Zhang Y, Cheng Y, Gao Y, Feng X, Dong M, Cao Z, Chen S, Yu H, Zhao Z, Zhang X, Liu J, Mori Y, Fan X, Meltzer SJ.

Sci Rep. 2013 Oct 3;3:2838. doi: 10.1038/srep02838.

44.

Long non-coding RNA HNF1A-AS1 regulates proliferation and migration in oesophageal adenocarcinoma cells.

Yang X, Song JH, Cheng Y, Wu W, Bhagat T, Yu Y, Abraham JM, Ibrahim S, Ravich W, Roland BC, Khashab M, Singh VK, Shin EJ, Yang X, Verma AK, Meltzer SJ, Mori Y.

Gut. 2014 Jun;63(6):881-90. doi: 10.1136/gutjnl-2013-305266. Epub 2013 Sep 2.

45.

Endoglin promoter hypermethylation identifies a field defect in human primary esophageal cancer.

Jin Z, Zhao Z, Cheng Y, Dong M, Zhang X, Wang L, Fan X, Feng X, Mori Y, Meltzer SJ.

Cancer. 2013 Oct 15;119(20):3604-9. doi: 10.1002/cncr.28276. Epub 2013 Jul 24.

46.

Evidence for enhanced telomerase activity in Barrett's esophagus with dysplasia and adenocarcinoma.

Merchant NB, Dutta SK, Girotra M, Arora M, Meltzer SJ.

Asian Pac J Cancer Prev. 2013;14(2):679-83.

47.

MicroRNA-224 negatively regulates p21 expression during late neoplastic progression in inflammatory bowel disease.

Olaru AV, Yamanaka S, Vazquez C, Mori Y, Cheng Y, Abraham JM, Bayless TM, Harpaz N, Selaru FM, Meltzer SJ.

Inflamm Bowel Dis. 2013 Mar;19(3):471-80. doi: 10.1097/MIB.0b013e31827e78eb.

48.

A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis.

Wang LD, Bi X, Song X, Pohl NM, Cheng Y, Zhou Y, Shears S, Ansong E, Xing M, Wang S, Xu XC, Huang P, Xu L, Wang L, Fan Z, Zhao X, Dong H, Meltzer SJ, Ding I, Yang W.

Mol Carcinog. 2013 Nov;52 Suppl 1:E80-6. doi: 10.1002/mc.22016. Epub 2013 Feb 6.

49.

Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA, AFAP1-AS1, in Barrett's esophagus and esophageal adenocarcinoma.

Wu W, Bhagat TD, Yang X, Song JH, Cheng Y, Agarwal R, Abraham JM, Ibrahim S, Bartenstein M, Hussain Z, Suzuki M, Yu Y, Chen W, Eng C, Greally J, Verma A, Meltzer SJ.

Gastroenterology. 2013 May;144(5):956-966.e4. doi: 10.1053/j.gastro.2013.01.019. Epub 2013 Jan 16.

50.

SILAC-based quantitative proteomic analysis of gastric cancer secretome.

Marimuthu A, Subbannayya Y, Sahasrabuddhe NA, Balakrishnan L, Syed N, Sekhar NR, Katte TV, Pinto SM, Srikanth SM, Kumar P, Pawar H, Kashyap MK, Maharudraiah J, Ashktorab H, Smoot DT, Ramaswamy G, Kumar RV, Cheng Y, Meltzer SJ, Roa JC, Chaerkady R, Prasad TS, Harsha HC, Chatterjee A, Pandey A.

Proteomics Clin Appl. 2013 Jun;7(5-6):355-66. doi: 10.1002/prca.201200069. Epub 2013 May 21.

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