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The Autoimmune Regulator (Aire) transactivates HLA-G gene expression in thymic epithelial cells.

Melo-Lima BL, Poras I, Passos GA, Carosella ED, Donadi EA, Moreau P.

Immunology. 2019 Jul 19. doi: 10.1111/imm.13099. [Epub ahead of print]


Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus.

Clave E, Araujo IL, Alanio C, Patin E, Bergstedt J, Urrutia A, Lopez-Lastra S, Li Y, Charbit B, MacPherson CR, Hasan M, Melo-Lima BL, Douay C, Saut N, Germain M, Trégouët DA, Morange PE, Fontes M, Duffy D, Di Santo JP, Quintana-Murci L, Albert ML, Toubert A; Milieu Intérieur Consortium.

Sci Transl Med. 2018 Sep 5;10(457). pii: eaao2966. doi: 10.1126/scitranslmed.aao2966.


The Attenuated Live Yellow Fever Virus 17D Infects the Thymus and Induces Thymic Transcriptional Modifications of Immunomodulatory Genes in C57BL/6 and BALB/C Mice.

Melo-Lima BL, Espósito DL, da Fonseca BA, Figueiredo LT, Moreau P, Donadi EA.

Autoimmune Dis. 2015;2015:503087. doi: 10.1155/2015/503087. Epub 2015 Sep 17.


Differential transcript profiles of MHC class Ib(Qa-1, Qa-2, and Qa-10) and Aire genes during the ontogeny of thymus and other tissues.

Melo-Lima BL, Evangelista AF, de Magalhães DA, Passos GA, Moreau P, Donadi EA.

J Immunol Res. 2014;2014:159247. doi: 10.1155/2014/159247. Epub 2014 Apr 16.

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