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Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α.

Melo HM, Seixas da Silva GDS, Sant'Ana MR, Teixeira CVL, Clarke JR, Miya Coreixas VS, de Melo BC, Fortuna JTS, Forny-Germano L, Ledo JH, Oliveira MS, Figueiredo CP, Pardossi-Piquard R, Checler F, Delgado-García JM, Gruart A, Velloso LA, Balthazar MLF, Cintra DE, Ferreira ST, De Felice FG.

Cell Rep. 2020 Feb 18;30(7):2180-2194.e8. doi: 10.1016/j.celrep.2020.01.072.


LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis.

de Oliveira J, Engel DF, de Paula GC, Melo HM, Lopes SC, Ribeiro CT, Delanogare E, Moreira JCF, Gelain DP, Prediger RD, Gabilan NH, Moreira ELG, Ferreira ST, de Bem AF.

J Alzheimers Dis. 2020;73(2):585-596. doi: 10.3233/JAD-190742.


Osmotic adjustment in cowpea plants: Interference of methods for estimating osmotic potential at full turgor.

Dourado PRM, de Souza ER, Lins CMT, de Melo HF, Bentzen Santos HR, Monteiro DR, Paulino MKSS, de Carvalho Leal LY.

Plant Physiol Biochem. 2019 Dec;145:114-119. doi: 10.1016/j.plaphy.2019.10.020. Epub 2019 Oct 18.


Fundraising and vote distribution: A non-equilibrium statistical approach.

Melo HPM, Araújo NAM, Andrade JS Jr.

PLoS One. 2019 Oct 30;14(10):e0223059. doi: 10.1371/journal.pone.0223059. eCollection 2019.


Resting Cardiac Vagal Tone is Associated with Long-Term Frustration Level of Mental Workload: Ultra-short Term Recording Reliability.

Melo HM, Hoeller AA, Walz R, Takase E.

Appl Psychophysiol Biofeedback. 2020 Mar;45(1):1-9. doi: 10.1007/s10484-019-09445-z.


Soft tissue facial profile changes after orthodontic treatment with or without tooth extractions in Class I malocclusion patients: A comparative study.

Freitas BV, Rodrigues VP, Rodrigues MF, de Melo HVF, Dos Santos PCF.

J Oral Biol Craniofac Res. 2019 Apr-Jun;9(2):172-176. doi: 10.1016/j.jobcr.2018.07.003. Epub 2018 Jul 10.


Omega 3-DHA and Delta-Tocotrienol Modulate Lipid Droplet Biogenesis and Lipophagy in Breast Cancer Cells: the Impact in Cancer Aggressiveness.

Pizato N, Kiffer LFMV, Luzete BC, Assumpção JAF, Correa LH, Melo HAB, Sant'Ana LP, Ito MK, Magalhães KG.

Nutrients. 2019 May 28;11(6). pii: E1199. doi: 10.3390/nu11061199.


Antibiofilm activity of the essential oil of citronella (Cymbopogon nardus) and its major component, geraniol, on the bacterial biofilms of Staphylococcus aureus.

Pontes EKU, Melo HM, Nogueira JWA, Firmino NCS, de Carvalho MG, Catunda Júnior FEA, Cavalcante TTA.

Food Sci Biotechnol. 2018 Oct 30;28(3):633-639. doi: 10.1007/s10068-018-0502-2. eCollection 2019 Jun.


Deep Brain Stimulation for Obesity: A Review and Future Directions.

Formolo DA, Gaspar JM, Melo HM, Eichwald T, Zepeda RJ, Latini A, Okun MS, Walz R.

Front Neurosci. 2019 Apr 18;13:323. doi: 10.3389/fnins.2019.00323. eCollection 2019. Review.


Impact of PI-RADS v2 on indication of prostate biopsy.

Rozas GQ, Saad LS, Melo HJFE, Gabrielle HAA, Szejnfeld J.

Int Braz J Urol. 2019 May-Jun;45(3):486-494. doi: 10.1590/S1677-5538.IBJU.2018.0564.


Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health.

Melo HM, Santos LE, Ferreira ST.

Front Neurosci. 2019 Mar 26;13:265. doi: 10.3389/fnins.2019.00265. eCollection 2019. Review.


TRPV1 promotes opioid analgesia during inflammation.

Basso L, Aboushousha R, Fan CY, Iftinca M, Melo H, Flynn R, Agosti F, Hollenberg MD, Thompson R, Bourinet E, Trang T, Altier C.

Sci Signal. 2019 Apr 2;12(575). pii: eaav0711. doi: 10.1126/scisignal.aav0711.


Congenital Aneurysm of the Right Atrium: Two Cases Report.

Melo H, Moraes Neto F, Lapa C, Moraes CR.

Braz J Cardiovasc Surg. 2019 Jan-Feb;34(1):104-106. doi: 10.21470/1678-9741-2018-0047.


Long-term consequences of the absence of leptin signaling in early life.

Ramos-Lobo AM, Teixeira PD, Furigo IC, Melo HM, de M Lyra E Silva N, De Felice FG, Donato J Jr.

Elife. 2019 Jan 29;8. pii: e40970. doi: 10.7554/eLife.40970.


Detection of Toxoplasma gondii in Crassostrea spp. oysters cultured in an estuarine region in eastern Amazon.

Monteiro TRM, Rocha KS, Silva J, Mesquita GSS, Rosário MKS, Ferreira MFS, Honorio BET, Melo HFR, Barros FNL, Scofield A, Abel I, Moraes CCG.

Zoonoses Public Health. 2019 May;66(3):296-300. doi: 10.1111/zph.12564. Epub 2019 Jan 27.


Potential Effects of Aspirin on Lysosomal Biogenesis and Amyloid-β Clearance: An Old Drug and Novel Insights in Alzheimer's Disease Therapy.

Melo HM.

J Neurosci. 2019 Jan 9;39(2):197-198. doi: 10.1523/JNEUROSCI.2283-18.2018. No abstract available.


Objectively measured physical activity levels and sedentary time in children and adolescents with sickle cell anemia.

Melo HN, Stoots SJ, Pool MA, Carvalho VO, Aragão MLC, Gurgel RQ, Agyemang C, Cipolotti R.

PLoS One. 2018 Dec 6;13(12):e0208916. doi: 10.1371/journal.pone.0208916. eCollection 2018.


Prevalence and risk factors of syphilis and human immunodeficiency virus co-infection at a university hospital in Brazil.

Santos AMG, Souza Júnior VR, Melo FL, Aquino AECA, Ramos MOA, Araújo LM, Lira CR, Sobral PM, Figueiroa F, Melo HRL, Araújo PSR.

Rev Soc Bras Med Trop. 2018 Nov-Dec;51(6):813-818. doi: 10.1590/0037-8682-0097-2018.


Itch induced by peripheral mu opioid receptors is dependent on TRPV1-expressing neurons and alleviated by channel activation.

Melo H, Basso L, Iftinca M, MacNaughton WK, Hollenberg MD, McKay DM, Altier C.

Sci Rep. 2018 Oct 19;8(1):15551. doi: 10.1038/s41598-018-33620-7.


The price of a vote: Diseconomy in proportional elections.

Melo HPM, Reis SDS, Moreira AA, Makse HA, Andrade JS Jr.

PLoS One. 2018 Aug 22;13(8):e0201654. doi: 10.1371/journal.pone.0201654. eCollection 2018.


Ultra-short heart rate variability recording reliability: The effect of controlled paced breathing.

Melo HM, Martins TC, Nascimento LM, Hoeller AA, Walz R, Takase E.

Ann Noninvasive Electrocardiol. 2018 Sep;23(5):e12565. doi: 10.1111/anec.12565. Epub 2018 Jun 4.


Effect of vegetation on cutaneous leishmaniasis in Paraná, Brazil.

Melo HA, Rossoni DF, Teodoro U.

Mem Inst Oswaldo Cruz. 2018 May 14;113(6):e170505. doi: 10.1590/0074-02760170505.


Treatment of chikungunya chronic arthritis: A systematic review.

Sales GMPG, Barbosa ICP, Canejo Neta LMS, Melo PL, Leitão RA, Melo HMA.

Rev Assoc Med Bras (1992). 2018 Jan;64(1):63-70. doi: 10.1590/1806-9282.64.01.63. Review.


Plant-associated bacteria mitigate drought stress in soybean.

Martins SJ, Rocha GA, de Melo HC, de Castro Georg R, Ulhôa CJ, de Campos Dianese É, Oshiquiri LH, da Cunha MG, da Rocha MR, de Araújo LG, Vaz KS, Dunlap CA.

Environ Sci Pollut Res Int. 2018 May;25(14):13676-13686. doi: 10.1007/s11356-018-1610-5. Epub 2018 Mar 3.


Brain STAT5 signaling modulates learning and memory formation.

Furigo IC, Melo HM, Lyra E Silva NM, Ramos-Lobo AM, Teixeira PDS, Buonfiglio DC, Wasinski F, Lima ER, Higuti E, Peroni CN, Bartolini P, Soares CRJ, Metzger M, de Felice FG, Donato J Jr.

Brain Struct Funct. 2018 Jun;223(5):2229-2241. doi: 10.1007/s00429-018-1627-z. Epub 2018 Feb 19.


Development of an electronic nose to characterize odours emitted from different stages in a wastewater treatment plant.

Blanco-Rodríguez A, Camara VF, Campo F, Becherán L, Durán A, Vieira VD, de Melo H, Garcia-Ramirez AR.

Water Res. 2018 May 1;134:92-100. doi: 10.1016/j.watres.2018.01.067. Epub 2018 Feb 3.


Tooth loss and craniofacial factors associated with changes in mandibular condylar morphology.

Rodrigues VP, Freitas BV, de Oliveira ICV, Dos Santos PCF, de Melo HVF, Bosio J.

Cranio. 2019 Sep;37(5):310-316. doi: 10.1080/08869634.2018.1431591. Epub 2018 Jan 29.


Corrigendum: Occurrence of qnrB1 and qnrB12 genes, mutation in gyrA and ramR, and expression of efflux pumps in isolates of Klebsiella pneumoniae carriers of bla KPC-2.

Scavuzzi AML, Veras DL, Maciel MAV, de Melo HRL, Alves LC, Brayner FA, Lopes ACS.

J Med Microbiol. 2018 Jan;67(1):144. doi: 10.1099/jmm.0.000650. No abstract available.


Cost-effectiveness of bariatric surgery in adolescents with severe obesity in the UK.

Panca M, Viner RM, White B, Pandya T, Melo H, Adamo M, Batterham R, Christie D, Kinra S, Morris S.

Clin Obes. 2018 Apr;8(2):105-113. doi: 10.1111/cob.12232. Epub 2017 Dec 10.


The influence of a diet based on flaxseed, an omega-3 source, during different developmental periods, on the blood pressure of rats submitted to stress.

Meneses JA, Trugilho LA, Lima SA, Freitas ACF, Melo HS, Ferreira MR, Velarde LGC, Brandão FZ, Rocha GS, Boaventura GT.

J Matern Fetal Neonatal Med. 2019 May;32(9):1516-1522. doi: 10.1080/14767058.2017.1407309. Epub 2017 Dec 12.


Water potential in soil and Atriplex nummularia (phytoremediator halophyte) under drought and salt stresses.

de Melo HF, de Souza ER, de Almeida BG, Mulas M.

Int J Phytoremediation. 2018 Feb 23;20(3):249-255. doi: 10.1080/15226514.2017.1374334.


Use of the Coding Causes of Death in HIV in the classification of deaths in Northeastern Brazil.

Alves DN, Bresani-Salvi CC, Batista JDL, Ximenes RAA, Miranda-Filho DB, Melo HRL, Albuquerque MFPM.

Rev Saude Publica. 2017;51:88. doi: 10.11606/S1518-8787.2017051000124. Epub 2017 Sep 21. English, Portuguese.


Spatial distribution of cutaneous leishmaniasis in the state of Paraná, Brazil.

Melo HA, Rossoni DF, Teodoro U.

PLoS One. 2017 Sep 22;12(9):e0185401. doi: 10.1371/journal.pone.0185401. eCollection 2017.


Plectranthus amboinicus essential oil and carvacrol bioactive against planktonic and biofilm of oxacillin- and vancomycin-resistant Staphylococcus aureus.

Vasconcelos SECB, Melo HM, Cavalcante TTA, Júnior FEAC, de Carvalho MG, Menezes FGR, de Sousa OV, Costa RA.

BMC Complement Altern Med. 2017 Sep 16;17(1):462. doi: 10.1186/s12906-017-1968-9.


In Vitro Antibacterial and Antibiofilm Activity of Lippia alba Essential Oil, Citral, and Carvone against Staphylococcus aureus.

Porfírio EM, Melo HM, Pereira AMG, Cavalcante TTA, Gomes GA, de Carvalho MG, Costa RA, Júnior FEAC.

ScientificWorldJournal. 2017;2017:4962707. doi: 10.1155/2017/4962707. Epub 2017 Aug 3.


Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model.

Diniz LP, Tortelli V, Matias I, Morgado J, Bérgamo Araujo AP, Melo HM, Seixas da Silva GS, Alves-Leon SV, de Souza JM, Ferreira ST, De Felice FG, Gomes FCA.

J Neurosci. 2017 Jul 12;37(28):6797-6809. doi: 10.1523/JNEUROSCI.3351-16.2017. Epub 2017 Jun 12.


Physical activity level and performance in the six-minute walk test of children and adolescents with sickle cell anemia.

Melo HN, Stoots SJ, Pool MA, Carvalho VO, Almeida LOC, Aragão MLC, Agyemang C, Cipolotti R.

Rev Bras Hematol Hemoter. 2017 Apr - Jun;39(2):133-139. doi: 10.1016/j.bjhh.2017.02.009. Epub 2017 Mar 31.


Allergic contact dermatitis caused by (meth)acrylates in nail cosmetic products in users and nail technicians - a 5-year study.

Raposo I, Lobo I, Amaro C, Lobo ML, Melo H, Parente J, Pereira T, Rocha J, Cunha AP, Baptista A, Serrano P, Correia T, Travassos AR, Dias M, Pereira F, Gonçalo M.

Contact Dermatitis. 2017 Dec;77(6):356-359. doi: 10.1111/cod.12817. Epub 2017 May 15.


Occurrence of qnrB1 and qnrB12 genes, mutation in gyrA and ramR, and expression of efflux pumps in isolates of Klebsiella pneumoniae carriers of blaKPC-2.

Scavuzzi AML, Maciel MAV, de Melo HRL, Alves LC, Brayner FA, Lopes ACS.

J Med Microbiol. 2017 Apr;66(4):477-484. doi: 10.1099/jmm.0.000452. Epub 2017 Apr 28.


Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons.

Seixas da Silva GS, Melo HM, Lourenco MV, Lyra E Silva NM, de Carvalho MB, Alves-Leon SV, de Souza JM, Klein WL, da-Silva WS, Ferreira ST, De Felice FG.

J Biol Chem. 2017 May 5;292(18):7395-7406. doi: 10.1074/jbc.M116.753525. Epub 2017 Mar 16.


Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice.

Brito-Moreira J, Lourenco MV, Oliveira MM, Ribeiro FC, Ledo JH, Diniz LP, Vital JFS, Magdesian MH, Melo HM, Barros-Aragão F, de Souza JM, Alves-Leon SV, Gomes FCA, Clarke JR, Figueiredo CP, De Felice FG, Ferreira ST.

J Biol Chem. 2017 May 5;292(18):7327-7337. doi: 10.1074/jbc.M116.761189. Epub 2017 Mar 10.


Electrochemical Impedance Spectroscopy in a Droplet of Solution for the Investigation of Liquid/Solid Interface.

Molena de Assis C, Ho TH, de Melo HG, Keddam M, Turmine M, Vivier V.

Anal Chem. 2016 Dec 20;88(24):12108-12115. doi: 10.1021/acs.analchem.6b02795. Epub 2016 Dec 8.


Evaluation of a web-based registry of inherited bleeding disorders: a descriptive study of the Brazilian experience with HEMOVIDAweb Coagulopatias.

Rezende SM, Rodrigues SH, Brito KN, da Silva DL, Santo ML, Simões BJ, Genovez G, Melo HT, Araújo JP, Barca DA; HEMOVIDAweb Coagulopatias Study Group.

Orphanet J Rare Dis. 2017 Feb 10;12(1):27. doi: 10.1186/s13023-016-0560-6.


Human mobility in large cities as a proxy for crime.

Caminha C, Furtado V, Pequeno TH, Ponte C, Melo HP, Oliveira EA, Andrade JS Jr.

PLoS One. 2017 Feb 3;12(2):e0171609. doi: 10.1371/journal.pone.0171609. eCollection 2017.


Predictors of immunodeficiency-related death in a cohort of low-income people living with HIV: a competing risks survival analysis.

Albuquerque MF, Alves DN, Bresani Salvi CC, Batista JD, Ximenes RA, Miranda-Filho DB, Melo HR, Maruza M, Montarroyos UR.

Epidemiol Infect. 2017 Apr;145(5):914-924. doi: 10.1017/S0950268816003149. Epub 2017 Jan 9.


Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.

Ledo JH, Azevedo EP, Beckman D, Ribeiro FC, Santos LE, Razolli DS, Kincheski GC, Melo HM, Bellio M, Teixeira AL, Velloso LA, Foguel D, De Felice FG, Ferreira ST.

J Neurosci. 2016 Nov 30;36(48):12106-12116.


The stress protein heat shock cognate 70 (Hsc70) inhibits the Transient Receptor Potential Vanilloid type 1 (TRPV1) channel.

Iftinca M, Flynn R, Basso L, Melo H, Aboushousha R, Taylor L, Altier C.

Mol Pain. 2016 Aug 24;12. pii: 1744806916663945. doi: 10.1177/1744806916663945. Print 2016.


Origins of emotional consciousness.

Melo HL, Koscik TR, Vrantsidis TH, Hathaway G, Cunningham WA.

Behav Brain Sci. 2016 Jan;39:e187. doi: 10.1017/S0140525X15002174.


Corrigendum: Statistical Signs of Social Influence on Suicides.

Melo HP, Moreira AA, Batista É, Makse HA, Andrade JS.

Sci Rep. 2015 Dec 18;5:15944. doi: 10.1038/srep15944. No abstract available.


Multifocal skeletal tuberculosis in an immunocompetent patient: a case report.

de Araujo PS, de Melo HR, de Melo FL, Medeiros Z, Maciel MA, Florêncio R, Brandão E.

BMC Infect Dis. 2015 Jun 20;15:235. doi: 10.1186/s12879-015-0985-x.

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