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Items: 1 to 50 of 210

1.

Increased EGFR Phosphorylation Correlates with Higher Programmed Death Ligand-1 Expression: Analysis of TKI-Resistant Lung Cancer Cell Lines.

Suda K, Rozeboom L, Furugaki K, Yu H, Melnick MAC, Ellison K, Rivard CJ, Politi K, Mitsudomi T, Hirsch FR.

Biomed Res Int. 2017;2017:7694202. doi: 10.1155/2017/7694202. Epub 2017 Oct 8.

2.

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer.

Gettinger S, Choi J, Hastings K, Truini A, Datar I, Sowell R, Wurtz A, Dong W, Cai G, Melnick MA, Du VY, Schlessinger J, Goldberg SB, Chiang A, Sanmamed MF, Melero I, Agorreta J, Montuenga LM, Lifton R, Ferrone S, Kavathas P, Rimm DL, Kaech SM, Schalper K, Herbst RS, Politi K.

Cancer Discov. 2017 Dec;7(12):1420-1435. doi: 10.1158/2159-8290.CD-17-0593. Epub 2017 Oct 12.

PMID:
29025772
3.

Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones.

Wagman AS, Cirz R, McEnroe G, Aggen J, Linsell MS, Goldblum AA, Lopez S, Gomez M, Miller G, Simons LJ, Belliotti TR, Harris CR, Poel TJ, Melnick MJ, Gaston RD, Moser HE.

ChemMedChem. 2017 Oct 20;12(20):1687-1692. doi: 10.1002/cmdc.201700426. Epub 2017 Oct 2.

PMID:
28881459
4.

Therapy-induced E-cadherin downregulation alters expression of programmed death ligand-1 in lung cancer cells.

Suda K, Rozeboom L, Rivard CJ, Yu H, Ellison K, Melnick MAC, Hinz TK, Chan D, Heasley LE, Politi K, Mitsudomi T, Hirsch FR.

Lung Cancer. 2017 Jul;109:1-8. doi: 10.1016/j.lungcan.2017.04.010. Epub 2017 Apr 19.

PMID:
28577937
5.

Perceptual training profoundly alters binocular rivalry through both sensory and attentional enhancements.

Dieter KC, Melnick MD, Tadin D.

Proc Natl Acad Sci U S A. 2016 Oct 24. pii: 201602722. [Epub ahead of print]

6.

Oncogenic EGFR Represses the TET1 DNA Demethylase to Induce Silencing of Tumor Suppressors in Cancer Cells.

Forloni M, Gupta R, Nagarajan A, Sun LS, Dong Y, Pirazzoli V, Toki M, Wurtz A, Melnick MA, Kobayashi S, Homer RJ, Rimm DL, Gettinger SJ, Politi K, Dogra SK, Wajapeyee N.

Cell Rep. 2016 Jul 12;16(2):457-471. doi: 10.1016/j.celrep.2016.05.087. Epub 2016 Jun 23.

7.

Relearning to See in Cortical Blindness.

Melnick MD, Tadin D, Huxlin KR.

Neuroscientist. 2016 Apr;22(2):199-212. doi: 10.1177/1073858415621035. Epub 2015 Dec 10. Review. Erratum in: Neuroscientist. 2016 Apr;22(2):213.

8.

Visual recovery in cortical blindness is limited by high internal noise.

Cavanaugh MR, Zhang R, Melnick MD, Das A, Roberts M, Tadin D, Carrasco M, Huxlin KR.

J Vis. 2015;15(10):9. doi: 10.1167/15.10.9.

9.

Do Physical Therapy Interventions Affect Urinary Incontinence and Quality of Life in People with Multiple Sclerosis?: An Evidence-Based Review.

Block V, Rivera M, Melnick M, Allen DD.

Int J MS Care. 2015 Jul-Aug;17(4):172-80. doi: 10.7224/1537-2073.2014-031.

10.

CMV-induced embryonic mouse organ of corti dysplasia: Network architecture of dysfunctional lateral inhibition.

Melnick M, Jaskoll T.

Birth Defects Res A Clin Mol Teratol. 2015 Jul;103(7):573-82. doi: 10.1002/bdra.23386. Epub 2015 Jul 14.

11.

When can attention influence binocular rivalry?

Dieter KC, Melnick MD, Tadin D.

Atten Percept Psychophys. 2015 Aug;77(6):1908-18. doi: 10.3758/s13414-015-0905-6.

12.

Comorbidity and functional mobility in persons with Parkinson disease.

King LA, Priest KC, Nutt J, Chen Y, Chen Z, Melnick M, Horak F.

Arch Phys Med Rehabil. 2014 Nov;95(11):2152-7. doi: 10.1016/j.apmr.2014.07.396. Epub 2014 Aug 4.

13.

CMV-induced pathology: pathway and gene-gene interaction analysis.

Melnick M, Deluca KA, Jaskoll T.

Exp Mol Pathol. 2014 Aug;97(1):154-65. doi: 10.1016/j.yexmp.2014.06.011. Epub 2014 Jun 28.

PMID:
24984270
14.

Feasibility of Computer-Based Videogame Therapy for Children with Cerebral Palsy.

Radtka S, Hone R, Brown C, Mastick J, Melnick ME, Dowling GA.

Games Health J. 2013 Aug;2(4):222-228.

15.

Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J.

Cancer Discov. 2014 May;4(5):606-19. doi: 10.1158/2159-8290.CD-13-0741. Epub 2014 Feb 17.

16.

A strong interactive link between sensory discriminations and intelligence.

Melnick MD, Harrison BR, Park S, Bennetto L, Tadin D.

Curr Biol. 2013 Jun 3;23(11):1013-7. doi: 10.1016/j.cub.2013.04.053. Epub 2013 May 23.

17.

Feasibility of adapting a classroom balance training program to a video game platform for people with Parkinson's disease.

Dowling GA, Hone R, Brown C, Mastick J, Melnick M.

Telemed J E Health. 2013 Apr;19(4):298-304. doi: 10.1089/tmj.2012.0055.

PMID:
23540279
18.

Cytomegalovirus-induced salivary gland pathology: AREG, FGF8, TNF-α, and IL-6 signal dysregulation and neoplasia.

Melnick M, Deluca KA, Sedghizadeh PP, Jaskoll T.

Exp Mol Pathol. 2013 Apr;94(2):386-97. doi: 10.1016/j.yexmp.2013.01.005. Epub 2013 Feb 8.

PMID:
23399805
20.

An in vitro mouse model of congenital cytomegalovirus-induced pathogenesis of the inner ear cochlea.

Melnick M, Jaskoll T.

Birth Defects Res A Clin Mol Teratol. 2013 Feb;97(2):69-78. doi: 10.1002/bdra.23105. Epub 2012 Dec 26.

21.

HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation.

Takezawa K, Pirazzoli V, Arcila ME, Nebhan CA, Song X, de Stanchina E, Ohashi K, Janjigian YY, Spitzler PJ, Melnick MA, Riely GJ, Kris MG, Miller VA, Ladanyi M, Politi K, Pao W.

Cancer Discov. 2012 Oct;2(10):922-33. doi: 10.1158/2159-8290.CD-12-0108. Epub 2012 Sep 5.

22.

Potent inhibitors of LpxC for the treatment of Gram-negative infections.

Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels JD, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mullins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello DP, Warmus JS, Wishka DG.

J Med Chem. 2012 Jan 26;55(2):914-23. doi: 10.1021/jm2014748. Epub 2012 Jan 11.

PMID:
22175825
23.

Human cytomegalovirus and mucoepidermoid carcinoma of salivary glands: cell-specific localization of active viral and oncogenic signaling proteins is confirmatory of a causal relationship.

Melnick M, Sedghizadeh PP, Allen CM, Jaskoll T.

Exp Mol Pathol. 2012 Feb;92(1):118-25. doi: 10.1016/j.yexmp.2011.10.011. Epub 2011 Nov 10.

PMID:
22101257
24.

Small molecule inhibitors of the host cell COX/AREG/EGFR/ERK pathway attenuate cytomegalovirus-induced pathogenesis.

Melnick M, Abichaker G, Htet K, Sedghizadeh P, Jaskoll T.

Exp Mol Pathol. 2011 Aug;91(1):400-10. doi: 10.1016/j.yexmp.2011.04.014. Epub 2011 May 1.

25.

CRTC1 expression during normal and abnormal salivary gland development supports a precursor cell origin for mucoepidermoid cancer.

Jaskoll T, Htet K, Abichaker G, Kaye FJ, Melnick M.

Gene Expr Patterns. 2011 Jan-Feb;11(1-2):57-63. doi: 10.1016/j.gep.2010.09.003. Epub 2010 Sep 15.

26.

Development and validation of the Function In Sitting Test in adults with acute stroke.

Gorman SL, Radtka S, Melnick ME, Abrams GM, Byl NN.

J Neurol Phys Ther. 2010 Sep;34(3):150-60. doi: 10.1097/NPT.0b013e3181f0065f.

PMID:
20716989
27.

Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling.

Kockel L, Kerr KS, Melnick M, Brückner K, Hebrok M, Perrimon N.

PLoS Genet. 2010 Jun 17;6(6):e1000990. doi: 10.1371/journal.pgen.1000990.

28.

The use of biochemical and biophysical tools for triage of high-throughput screening hits - A case study with Escherichia coli phosphopantetheine adenylyltransferase.

Miller JR, Thanabal V, Melnick MM, Lall M, Donovan C, Sarver RW, Lee DY, Ohren J, Emerson D.

Chem Biol Drug Des. 2010 May;75(5):444-54. doi: 10.1111/j.1747-0285.2010.00957.x.

PMID:
20486930
29.

Cytomegalovirus induces stage-dependent enamel defects and misexpression of amelogenin, enamelin and dentin sialophosphoprotein in developing mouse molars.

Jaskoll T, Abichaker G, Htet K, Bringas P Jr, Morita S, Sedghizadeh PP, Melnick M.

Cells Tissues Organs. 2010;192(4):221-39. doi: 10.1159/000314909. Epub 2010 May 18.

PMID:
20484882
30.

Athletic participation and seatbelt omission among u.s. High school students.

Melnick MJ, Miller KE, Sabo DF, Barnes GM, Farrell MP.

Health Educ Behav. 2010 Feb;37(1):23-36. doi: 10.1177/1090198107308377. Epub 2009 Oct 1.

31.

Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm.

Melnick M, Phair RD, Lapidot SA, Jaskoll T.

BMC Dev Biol. 2009 Jun 6;9:32. doi: 10.1186/1471-213X-9-32.

32.

HIGH SCHOOL ATHLETIC PARTICIPATION AND ADOLESCENT SUICIDE: A Nationwide US Study.

Sabo D, Miller KE, Melnick MJ, Farrell MP, Barnes GM.

Int Rev Sociol Sport. 2005;40(1):5-23.

33.

Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development.

Jaskoll T, Abichaker G, Sedghizadeh PP, Bringas P Jr, Melnick M.

BMC Dev Biol. 2008 Mar 27;8:33. doi: 10.1186/1471-213X-8-33.

34.

Structure of a small-molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site.

Mochalkin I, Lightle S, Narasimhan L, Bornemeier D, Melnick M, Vanderroest S, McDowell L.

Protein Sci. 2008 Mar;17(3):577-82. doi: 10.1110/ps.073271408. Epub 2008 Jan 24.

35.

Cytomegalovirus inhibition of embryonic mouse tooth development: a model of the human amelogenesis imperfecta phenocopy.

Jaskoll T, Abichaker G, Jangaard N, Bringas P Jr, Melnick M.

Arch Oral Biol. 2008 May;53(5):405-15. doi: 10.1016/j.archoralbio.2007.11.014. Epub 2008 Jan 16.

36.

Athletic Involvement and Adolescent Delinquency.

Miller KE, Melnick MJ, Barnes GM, Sabo D, Farrell MP.

J Youth Adolesc. 2007 Jul;36(5):711-723.

37.

Characterization of substrate binding and catalysis in the potential antibacterial target N-acetylglucosamine-1-phosphate uridyltransferase (GlmU).

Mochalkin I, Lightle S, Zhu Y, Ohren JF, Spessard C, Chirgadze NY, Banotai C, Melnick M, McDowell L.

Protein Sci. 2007 Dec;16(12):2657-66.

38.

Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model.

Melnick M, Mocarski ES, Abichaker G, Huang J, Jaskoll T.

BMC Dev Biol. 2006 Sep 7;6:42.

39.

Synthesis and structure-activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents.

Vara Prasad JV, Boyer FE, Chupak L, Dermyer M, Ding Q, Gavardinas K, Hagen SE, Huband MD, Jiao W, Kaneko T, Maiti SN, Melnick M, Romero K, Patterson M, Wu X.

Bioorg Med Chem Lett. 2006 Oct 15;16(20):5392-7. Epub 2006 Aug 9.

PMID:
16901693
40.

Untangling the Links among Athletic Involvement, Gender, Race, and Adolescent Academic Outcomes.

Miller KE, Melnick MJ, Barnes GM, Farrell MP, Sabo D.

Sociol Sport J. 2005 Jun;22(2):178-193.

41.

The structure of the carboxyltransferase component of acetyl-coA carboxylase reveals a zinc-binding motif unique to the bacterial enzyme.

Bilder P, Lightle S, Bainbridge G, Ohren J, Finzel B, Sun F, Holley S, Al-Kassim L, Spessard C, Melnick M, Newcomer M, Waldrop GL.

Biochemistry. 2006 Feb 14;45(6):1712-22.

PMID:
16460018
42.

Gender/Racial Differences in Jock Identity, Dating, and Adolescent Sexual Risk.

Miller KE, Farrell MP, Barnes GM, Melnick MJ, Sabo D.

J Youth Adolesc. 2005 Apr;34(2):123-136.

43.

Jocks, gender, binge drinking, and adolescent violence.

Miller KE, Melnick MJ, Farrell MP, Sabo DF, Barnes GM.

J Interpers Violence. 2006 Jan;21(1):105-20.

44.

Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice.

Melnick M, Petryk A, Abichaker G, Witcher D, Person AD, Jaskoll T.

Arch Oral Biol. 2006 May;51(5):433-8. Epub 2005 Nov 14.

45.

Adolescent anabolic steroid use, gender, physical activity, and other problem behaviors*.

Miller KE, Hoffman JH, Barnes GM, Sabo D, Melnick MJ, Farrell MP.

Subst Use Misuse. 2005;40(11):1637-57.

PMID:
16253932
46.

Evaluation of CML model cell lines and imatinib mesylate response: determinants of signaling profiles.

Wetzel R, Goss VL, Norris B, Popova L, Melnick M, Smith BL.

J Immunol Methods. 2005 Oct 20;305(1):59-66. Epub 2005 Aug 24.

PMID:
16169003
47.

Meckel's cartilage differentiation is dependent on hedgehog signaling.

Melnick M, Witcher D, Bringas P Jr, Carlsson P, Jaskoll T.

Cells Tissues Organs. 2005;179(4):146-57.

PMID:
16046861
48.

FGF10/FGFR2b signaling plays essential roles during in vivo embryonic submandibular salivary gland morphogenesis.

Jaskoll T, Abichaker G, Witcher D, Sala FG, Bellusci S, Hajihosseini MK, Melnick M.

BMC Dev Biol. 2005 Jun 22;5:11.

50.

Bilateral asymmetry in Chinese families with cleft lip with or without cleft palate.

Neiswanger K, Cooper ME, Liu YE, Hu DN, Melnick M, Weinberg SM, Marazita ML.

Cleft Palate Craniofac J. 2005 Mar;42(2):192-6.

PMID:
15748111

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