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Items: 16


Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood.

Toepfner N, Herold C, Otto O, Rosendahl P, Jacobi A, Kräter M, Stächele J, Menschner L, Herbig M, Ciuffreda L, Ranford-Cartwright L, Grzybek M, Coskun Ü, Reithuber E, Garriss G, Mellroth P, Henriques-Normark B, Tregay N, Suttorp M, Bornhäuser M, Chilvers ER, Berner R, Guck J.

Elife. 2018 Jan 13;7. pii: e29213. doi: 10.7554/eLife.29213.


Analysis of IAV Replication and Co-infection Dynamics by a Versatile RNA Viral Genome Labeling Method.

Dou D, Hernández-Neuta I, Wang H, Östbye H, Qian X, Thiele S, Resa-Infante P, Kouassi NM, Sender V, Hentrich K, Mellroth P, Henriques-Normark B, Gabriel G, Nilsson M, Daniels R.

Cell Rep. 2017 Jul 5;20(1):251-263. doi: 10.1016/j.celrep.2017.06.021.


pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion.

Iovino F, Engelen-Lee JY, Brouwer M, van de Beek D, van der Ende A, Valls Seron M, Mellroth P, Muschiol S, Bergstrand J, Widengren J, Henriques-Normark B.

J Exp Med. 2017 Jun 5;214(6):1619-1630. doi: 10.1084/jem.20161668. Epub 2017 May 17.


Impact of AmpC Derepression on Fitness and Virulence: the Mechanism or the Pathway?

Pérez-Gallego M, Torrens G, Castillo-Vera J, Moya B, Zamorano L, Cabot G, Hultenby K, Albertí S, Mellroth P, Henriques-Normark B, Normark S, Oliver A, Juan C.

MBio. 2016 Oct 25;7(5). pii: e01783-16. doi: 10.1128/mBio.01783-16.


The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.

Sandalova T, Lee M, Henriques-Normark B, Hesek D, Mobashery S, Mellroth P, Achour A.

Mol Microbiol. 2016 Sep;101(6):954-67. doi: 10.1111/mmi.13435. Epub 2016 Jul 5.


Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.

Mellroth P, Sandalova T, Kikhney A, Vilaplana F, Hesek D, Lee M, Mobashery S, Normark S, Svergun D, Henriques-Normark B, Achour A.

MBio. 2014 Feb 11;5(1):e01120-13. doi: 10.1128/mBio.01120-13.


LytA, major autolysin of Streptococcus pneumoniae, requires access to nascent peptidoglycan.

Mellroth P, Daniels R, Eberhardt A, Rönnlund D, Blom H, Widengren J, Normark S, Henriques-Normark B.

J Biol Chem. 2012 Mar 30;287(14):11018-29. doi: 10.1074/jbc.M111.318584. Epub 2012 Feb 9.


Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae.

Olliver M, Hiew J, Mellroth P, Henriques-Normark B, Bergman P.

Infect Immun. 2011 Oct;79(10):4210-7. doi: 10.1128/IAI.05286-11. Epub 2011 Jul 25.


Control of intestinal Nod2-mediated peptidoglycan recognition by epithelium-associated lymphocytes.

Duerr CU, Salzman NH, Dupont A, Szabo A, Normark BH, Normark S, Locksley RM, Mellroth P, Hornef MW.

Mucosal Immunol. 2011 May;4(3):325-34. doi: 10.1038/mi.2010.71. Epub 2010 Oct 27.


Disulfide bond formation and cysteine exclusion in gram-positive bacteria.

Daniels R, Mellroth P, Bernsel A, Neiers F, Normark S, von Heijne G, Henriques-Normark B.

J Biol Chem. 2010 Jan 29;285(5):3300-9. doi: 10.1074/jbc.M109.081398. Epub 2009 Nov 24.


Peptidoglycan recognition proteins with amidase activity in early deuterostomes (Echinodermata).

Coteur G, Mellroth P, De Lefortery C, Gillan D, Dubois P, Communi D, Steiner H.

Dev Comp Immunol. 2007;31(8):790-804. Epub 2006 Dec 14.


PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity.

Mellroth P, Steiner H.

Biochem Biophys Res Commun. 2006 Dec 1;350(4):994-9. Epub 2006 Oct 4.


Ligand-induced dimerization of Drosophila peptidoglycan recognition proteins in vitro.

Mellroth P, Karlsson J, Håkansson J, Schultz N, Goldman WE, Steiner H.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6455-60. Epub 2005 Apr 20.


Monomeric and polymeric gram-negative peptidoglycan but not purified LPS stimulate the Drosophila IMD pathway.

Kaneko T, Goldman WE, Mellroth P, Steiner H, Fukase K, Kusumoto S, Harley W, Fox A, Golenbock D, Silverman N.

Immunity. 2004 May;20(5):637-49.


Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan.

Werner T, Borge-Renberg K, Mellroth P, Steiner H, Hultmark D.

J Biol Chem. 2003 Jul 18;278(29):26319-22. Epub 2003 May 30.


A scavenger function for a Drosophila peptidoglycan recognition protein.

Mellroth P, Karlsson J, Steiner H.

J Biol Chem. 2003 Feb 28;278(9):7059-64. Epub 2002 Dec 20.

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