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Items: 10

1.

Irreversible Inhibition of EGFR: Modeling the Combined Pharmacokinetic-Pharmacodynamic Relationship of Osimertinib and Its Active Metabolite AZ5104.

Yates JW, Ashton S, Cross D, Mellor MJ, Powell SJ, Ballard P.

Mol Cancer Ther. 2016 Oct;15(10):2378-2387. Epub 2016 Jul 20.

2.

Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor.

Finlay MR, Anderton M, Ashton S, Ballard P, Bethel PA, Box MR, Bradbury RH, Brown SJ, Butterworth S, Campbell A, Chorley C, Colclough N, Cross DA, Currie GS, Grist M, Hassall L, Hill GB, James D, James M, Kemmitt P, Klinowska T, Lamont G, Lamont SG, Martin N, McFarland HL, Mellor MJ, Orme JP, Perkins D, Perkins P, Richmond G, Smith P, Ward RA, Waring MJ, Whittaker D, Wells S, Wrigley GL.

J Med Chem. 2014 Oct 23;57(20):8249-67. doi: 10.1021/jm500973a. Epub 2014 Oct 1.

PMID:
25271963
3.

AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer.

Cross DA, Ashton SE, Ghiorghiu S, Eberlein C, Nebhan CA, Spitzler PJ, Orme JP, Finlay MR, Ward RA, Mellor MJ, Hughes G, Rahi A, Jacobs VN, Red Brewer M, Ichihara E, Sun J, Jin H, Ballard P, Al-Kadhimi K, Rowlinson R, Klinowska T, Richmond GH, Cantarini M, Kim DW, Ranson MR, Pao W.

Cancer Discov. 2014 Sep;4(9):1046-61. doi: 10.1158/2159-8290.CD-14-0337. Epub 2014 Jun 3.

4.

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family.

Gavine PR, Mooney L, Kilgour E, Thomas AP, Al-Kadhimi K, Beck S, Rooney C, Coleman T, Baker D, Mellor MJ, Brooks AN, Klinowska T.

Cancer Res. 2012 Apr 15;72(8):2045-56. doi: 10.1158/0008-5472.CAN-11-3034. Epub 2012 Feb 27.

5.

Social work with older immigrants & their families. Foreword.

Mellor MJ.

J Gerontol Soc Work. 2009 Jul;52(5):443-4. doi: 10.1080/01634370902983070. No abstract available.

PMID:
19585321
6.

Interdisciplinary Geriatric Education.

Solomon R, Mellor MJ.

J Gerontol Soc Work. 1992 Jun;18(1-2):175-186. doi: 10.1300/J083V18N03_13.

PMID:
28949860
7.

The Interdisciplinary Geriatric/Gerontological Team in the Academic Setting.

Mellor MJ, Solomon R.

J Gerontol Soc Work. 1992;18(3-4):203-215. doi: 10.1300/J083v18n01_14.

PMID:
28949885
8.

Interdisciplinary Geriatric Education.

Solomon R, Mellor MJ.

J Gerontol Soc Work. 1992;18(3-4):175-186. doi: 10.1300/J083v18n01_12.

PMID:
28949881
9.

Preface.

Mellor MJ, Solomon R.

J Gerontol Soc Work. 1992;18(3-4):xvii-xx. doi: 10.1300/J083v18n01_b.

PMID:
28949880
10.

The role of the family in long term home health care.

Zimmer AH, Mellor MJ.

Pride Inst J Long Term Home Health Care. 1982 Fall;1(2):20-5. No abstract available.

PMID:
10261961

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