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A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non-small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early Stage Disease.

Wang W, Huang L, Jin JY, Pi W, Ellsworth SG, Jolly S, Mellor AL, Machtay M, Kong FS.

Clin Cancer Res. 2019 Aug 30. pii: clincanres.1202.2019. doi: 10.1158/1078-0432.CCR-19-1202. [Epub ahead of print]


Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities.

Jiang X, Xu J, Liu M, Xing H, Wang Z, Huang L, Mellor AL, Wang W, Wu S.

Cancer Lett. 2019 Oct 10;462:23-32. doi: 10.1016/j.canlet.2019.07.017. Epub 2019 Jul 26.


Prevalence of sleep disturbance and its relationships with mental health and psychosocial issues in refugees and asylum seekers attending psychological services in Australia.

Lies J, Mellor A, Jobson L, Drummond SPA.

Sleep Health. 2019 Aug;5(4):335-343. doi: 10.1016/j.sleh.2019.06.002. Epub 2019 Jul 16.


IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.

Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LMF, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC.

Int Immunol. 2019 Mar 5;31(3):181-182. doi: 10.1093/intimm/dxz003. No abstract available.


Graph comparison via the nonbacktracking spectrum.

Mellor A, Grusovin A.

Phys Rev E. 2019 May;99(5-1):052309. doi: 10.1103/PhysRevE.99.052309.


Fuel Use During Exercise At Altitude In Women With Glucose-Fructose Ingestion.

O'Hara JP, Duckworth L, Black A, Woods DR, Mellor A, Boos C, Gallagher L, Tsakirides C, Arjomandkhah NC, Morrison DJ, Preston T, King RF.

Med Sci Sports Exerc. 2019 Jun 14. doi: 10.1249/MSS.0000000000002072. [Epub ahead of print]


Surgically Managed Ovarian Masses at the Royal Children's Hospital, Melbourne -19 Year Experience.

How JA, Marino JL, Grover SR, Heloury Y, Sullivan M, Mellor A, McNally O, Jayasinghe Y.

J Pediatr Surg. 2019 Sep;54(9):1913-1920. doi: 10.1016/j.jpedsurg.2019.05.005. Epub 2019 May 16.


Partner-assisted cognitive behavioural therapy for insomnia versus cognitive behavioural therapy for insomnia: a randomised controlled trial.

Mellor A, Hamill K, Jenkins MM, Baucom DH, Norton PJ, Drummond SPA.

Trials. 2019 May 8;20(1):262. doi: 10.1186/s13063-019-3334-3.


Immune control by amino acid catabolism during tumorigenesis and therapy.

Lemos H, Huang L, Prendergast GC, Mellor AL.

Nat Rev Cancer. 2019 Mar;19(3):162-175. doi: 10.1038/s41568-019-0106-z. Review.


Metabolic requirements for expanding and arming a clone army.

Mellor AL, Huang L.

Nat Immunol. 2019 Feb;20(2):118-120. doi: 10.1038/s41590-018-0299-4. No abstract available.


Non-flushing of IV administration sets: an under-recognised under-dosing risk.

Cooper DM, Rassam T, Mellor A.

Br J Nurs. 2018 Jul 26;27(14):S4-S12. doi: 10.12968/bjon.2018.27.14.S4.


A pilot investigation into the effects of acute normobaric hypoxia, high altitude exposure and exercise on serum angiotensin-converting enzyme, aldosterone and cortisol.

Cooke M, Cruttenden R, Mellor A, Lumb A, Pattman S, Burnett A, Boot C, Burnip L, Boos C, O'Hara J, Woods D.

J Renin Angiotensin Aldosterone Syst. 2018 Apr-Jun;19(2):1470320318782782. doi: 10.1177/1470320318782782.


The relationship between anxiety and acute mountain sickness.

Boos CJ, Bass M, O'Hara JP, Vincent E, Mellor A, Sevier L, Abdul-Razakq H, Cooke M, Barlow M, Woods DR.

PLoS One. 2018 Jun 21;13(6):e0197147. doi: 10.1371/journal.pone.0197147. eCollection 2018.


Remote physiological monitoring in an austere environment: a future for battlefield care provision?

Smyth MJ, Round JA, Mellor AJ.

J R Army Med Corps. 2018 Nov;164(6):410-413. doi: 10.1136/jramc-2017-000905. Epub 2018 May 14.


The effects of acute hypoxia on tissue oxygenation and circulating alarmins in healthy adults.

Boos CJ, Lamb CM, Midwinter M, Mellor A, Woods DR, Howley M, Stansfield T, Foster M, O'Hara JP.

Physiol Res. 2018 Dec 18;67(6):935-943. Epub 2018 May 10.


High Altitude Affects Nocturnal Non-linear Heart Rate Variability: PATCH-HA Study.

Boos CJ, Bye K, Sevier L, Bakker-Dyos J, Woods DR, Sullivan M, Quinlan T, Mellor A.

Front Physiol. 2018 Apr 16;9:390. doi: 10.3389/fphys.2018.00390. eCollection 2018.


Assessing the Nature of the Distribution of Localised States in Bulk GaAsBi.

Wilson T, Hylton NP, Harada Y, Pearce P, Alonso-Álvarez D, Mellor A, Richards RD, David JPR, Ekins-Daukes NJ.

Sci Rep. 2018 Apr 24;8(1):6457. doi: 10.1038/s41598-018-24696-2.


Continuous Glucose Monitoring at High Altitude-Effects on Glucose Homeostasis.

Hill NE, Deighton K, Matu J, Misra S, Oliver NS, Newman C, Mellor A, O'Hara J, Woods D.

Med Sci Sports Exerc. 2018 Aug;50(8):1679-1686. doi: 10.1249/MSS.0000000000001624.


Effects of sleep deprivation on component processes of working memory in younger and older adults.

Pasula EY, Brown GG, McKenna BS, Mellor A, Turner T, Anderson C, Drummond SPA.

Sleep. 2018 Mar 1;41(3). doi: 10.1093/sleep/zsx213.


Changes in balance and joint position sense during a 12-day high altitude trek: The British Services Dhaulagiri medical research expedition.

Clarke SB, Deighton K, Newman C, Nicholson G, Gallagher L, Boos CJ, Mellor A, Woods DR, O'Hara JP.

PLoS One. 2018 Jan 17;13(1):e0190919. doi: 10.1371/journal.pone.0190919. eCollection 2018.


Power supplies and equipment for military field research: lessons from the British Service Dhaulagiri Research Expedition 2016.

Howard M, Bakker-Dyos J, Gallagher L, O'Hara JP, Woods D, Mellor A.

J R Army Med Corps. 2018 Feb;164(1):41-45. doi: 10.1136/jramc-2017-000767. Epub 2017 Dec 25.


Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?

Mellor AL, Lemos H, Huang L.

Front Immunol. 2017 Oct 27;8:1360. doi: 10.3389/fimmu.2017.01360. eCollection 2017. Review.


The ability to self-monitor cognitive performance during 60 h total sleep deprivation and following 2 nights recovery sleep.

Boardman JM, Bei B, Mellor A, Anderson C, Sletten TL, Drummond SPA.

J Sleep Res. 2018 Aug;27(4):e12633. doi: 10.1111/jsr.12633. Epub 2017 Nov 20.


Direct Visualization of Au Atoms Bound to TiO2(110) O-Vacancies.

Mellor A, Humphrey D, Yim CM, Pang CL, Idriss H, Thornton G.

J Phys Chem C Nanomater Interfaces. 2017 Nov 9;121(44):24721-24725. doi: 10.1021/acs.jpcc.7b09608. Epub 2017 Oct 18.


IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients.

Wang W, Huang L, Jin JY, Jolly S, Zang Y, Wu H, Yan L, Pi W, Li L, Mellor AL, Kong FS.

Cancer Res. 2018 Feb 1;78(3):809-816. doi: 10.1158/0008-5472.CAN-17-2995. Epub 2017 Nov 8.


The role of neutrophil gelatinase-associated lipocalin (NGAL) in the detection of blast lung injury in a military population.

Lumley A, Osborn E, Mellor A, LaCroix E, Johnson G, Wallace M, Stacey M, Smith JE, Woods D.

J Crit Care. 2018 Feb;43:312-315. doi: 10.1016/j.jcrc.2017.08.047. Epub 2017 Sep 1.


The British Services Dhaulagiri Medical Research Expedition 2016: a unique military and civilian research collaboration.

Mellor A, Bakker-Dyos J, Howard M, Boos C, Cooke M, Vincent E, Scott P, O'Hara J, Clarke SB, Barlow M, Matu J, Deighton K, Hill N, Newman C, Cruttenden R, Holdsworth D, Woods D.

J R Army Med Corps. 2017 Dec;163(6):371-375. doi: 10.1136/jramc-2016-000700. Epub 2017 Oct 5.


Working Memory Capacity and Surgical Performance While Exposed to Mild Hypoxic Hypoxemia.

Parker PJ, Manley AJ, Shand R, O'Hara JP, Mellor A.

Aerosp Med Hum Perform. 2017 Oct 1;88(10):918-923. doi: 10.3357/AMHP.4761.2017.


Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity.

Zhu H, Lemos H, Bhatt B, Islam BN, Singh A, Gurav A, Huang L, Browning DD, Mellor A, Fulzele S, Singh N.

PLoS One. 2017 Sep 12;12(9):e0183484. doi: 10.1371/journal.pone.0183484. eCollection 2017.


Changes in appetite, energy intake, body composition, and circulating ghrelin constituents during an incremental trekking ascent to high altitude.

Matu J, O'Hara J, Hill N, Clarke S, Boos C, Newman C, Holdsworth D, Ispoglou T, Duckworth L, Woods D, Mellor A, Deighton K.

Eur J Appl Physiol. 2017 Sep;117(9):1917-1928. doi: 10.1007/s00421-017-3683-0. Epub 2017 Jul 24.


The Effect of Sex on Heart Rate Variability at High Altitude.

Boos CJ, Vincent E, Mellor A, O'Hara J, Newman C, Cruttenden R, Scott P, Cooke M, Matu J, Woods DR.

Med Sci Sports Exerc. 2017 Dec;49(12):2562-2569. doi: 10.1249/MSS.0000000000001384.


The effect of high altitude on central blood pressure and arterial stiffness.

Boos CJ, Vincent E, Mellor A, Woods DR, New C, Cruttenden R, Barlow M, Cooke M, Deighton K, Scott P, Clarke S, O'Hara J.

J Hum Hypertens. 2017 Nov;31(11):715-719. doi: 10.1038/jhh.2017.40. Epub 2017 May 25.


Smartphone-Enabled Heart Rate Variability and Acute Mountain Sickness.

Mellor A, Bakker-Dyos J, OʼHara J, Woods DR, Holdsworth DA, Boos CJ.

Clin J Sport Med. 2018 Jan;28(1):76-81. doi: 10.1097/JSM.0000000000000427.


Markers of physiological stress during exercise under conditions of normoxia, normobaric hypoxia, hypobaric hypoxia, and genuine high altitude.

Woods DR, O'Hara JP, Boos CJ, Hodkinson PD, Tsakirides C, Hill NE, Jose D, Hawkins A, Phillipson K, Hazlerigg A, Arjomandkhah N, Gallagher L, Holdsworth D, Cooke M, Green NDC, Mellor A.

Eur J Appl Physiol. 2017 May;117(5):893-900. doi: 10.1007/s00421-017-3573-5. Epub 2017 Mar 15.


Assessment of Cardiac Arrhythmias at Extreme High Altitude Using an Implantable Cardiac Monitor: REVEAL HA Study (REVEAL High Altitude).

Boos CJ, Holdsworth DA, Woods DR, O'Hara J, Brooks N, Macconnachie L, Bakker-Dyos J, Paisey J, Mellor A.

Circulation. 2017 Feb 21;135(8):812-814. doi: 10.1161/CIRCULATIONAHA.116.026584. No abstract available.


Heterogeneous out-of-equilibrium nonlinear q-voter model with zealotry.

Mellor A, Mobilia M, Zia RK.

Phys Rev E. 2017 Jan;95(1-1):012104. doi: 10.1103/PhysRevE.95.012104. Epub 2017 Jan 4.


Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14+ Monocytes.

Horvatinovich JM, Grogan EW, Norris M, Steinkasserer A, Lemos H, Mellor AL, Tcherepanova IY, Nicolette CA, DeBenedette MA.

J Immunol. 2017 Mar 15;198(6):2286-2301. doi: 10.4049/jimmunol.1600802. Epub 2017 Feb 13.


Manubrium-limited ministernotomy versus conventional sternotomy for aortic valve replacement (MAVRIC): study protocol for a randomised controlled trial.

Akowuah E, Goodwin AT, Owens WA, Hancock HC, Maier R, Kasim A, Mellor A, Khan K, Murphy G, Mason J.

Trials. 2017 Jan 28;18(1):46. doi: 10.1186/s13063-016-1768-4.


A comparison of substrate oxidation during prolonged exercise in men at terrestrial altitude and normobaric normoxia following the coingestion of 13C glucose and 13C fructose.

O'Hara JP, Woods DR, Mellor A, Boos C, Gallagher L, Tsakirides C, Arjomandkhah NC, Holdsworth DA, Cooke CB, Morrison DJ, Preston T, King RF.

Physiol Rep. 2017 Jan;5(1). pii: e13101. doi: 10.14814/phy2.13101.


A high-resolution operational forecast system for oil spill response in Belfast Lough.

Abascal AJ, Castanedo S, Núñez P, Mellor A, Clements A, Pérez B, Cárdenas M, Chiri H, Medina R.

Mar Pollut Bull. 2017 Jan 15;114(1):302-314. doi: 10.1016/j.marpolbul.2016.09.042. Epub 2016 Oct 3.


The Adrenocortical Response to Synthetic ACTH Following a Trek to High Altitude.

Mackey J, Mellor A, Watchorn J, Burnett A, Boot C, Woods D.

Horm Metab Res. 2016 Sep;48(10):658-663. Epub 2016 Sep 19.


An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis.

Sivaprakasam S, Gurav A, Paschall AV, Coe GL, Chaudhary K, Cai Y, Kolhe R, Martin P, Browning D, Huang L, Shi H, Sifuentes H, Vijay-Kumar M, Thompson SA, Munn DH, Mellor A, McGaha TL, Shiao P, Cutler CW, Liu K, Ganapathy V, Li H, Singh N.

Oncogenesis. 2016 Jun 27;5(6):e238. doi: 10.1038/oncsis.2016.38.


Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.

Huang L, Ou R, Rabelo de Souza G, Cunha TM, Lemos H, Mohamed E, Li L, Pacholczyk G, Randall J, Munn DH, Mellor AL.

PLoS Pathog. 2016 May 11;12(5):e1005615. doi: 10.1371/journal.ppat.1005615. eCollection 2016 May.


Deletion of LRP5 and LRP6 in dendritic cells enhances antitumor immunity.

Hong Y, Manoharan I, Suryawanshi A, Shanmugam A, Swafford D, Ahmad S, Chinnadurai R, Manicassamy B, He Y, Mellor AL, Thangaraju M, Munn DH, Manicassamy S.

Oncoimmunology. 2015 Dec 14;5(4):e1115941. eCollection 2016 Apr.


A Four-Way Comparison of Cardiac Function with Normobaric Normoxia, Normobaric Hypoxia, Hypobaric Hypoxia and Genuine High Altitude.

Boos CJ, O'Hara JP, Mellor A, Hodkinson PD, Tsakirides C, Reeve N, Gallagher L, Green ND, Woods DR.

PLoS One. 2016 Apr 21;11(4):e0152868. doi: 10.1371/journal.pone.0152868. eCollection 2016.


The Effects of Sex on Cardiopulmonary Responses to Acute Normobaric Hypoxia.

Boos CJ, Mellor A, O'Hara JP, Tsakirides C, Woods DR.

High Alt Med Biol. 2016 Jun;17(2):108-15. doi: 10.1089/ham.2015.0114. Epub 2016 Mar 23.


STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation.

Lemos H, Mohamed E, Huang L, Ou R, Pacholczyk G, Arbab AS, Munn D, Mellor AL.

Cancer Res. 2016 Apr 15;76(8):2076-81. doi: 10.1158/0008-5472.CAN-15-1456. Epub 2016 Mar 10.


Lessons learned while undertaking high altitude medical research in the Himalayas.

Mackey J, Mellor A.

J R Nav Med Serv. 2015;101(2):143-6.


Exercise HIMALAYAN SERPENT: feedback article.

France K, Mellor A.

J R Nav Med Serv. 2015;101(2):138-42.


IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance.

Munn DH, Mellor AL.

Trends Immunol. 2016 Mar;37(3):193-207. doi: 10.1016/ Epub 2016 Jan 31. Review.

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