Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 18

1.

LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.

Cobo-Vuilleumier N, Lorenzo PI, Rodríguez NG, Herrera Gómez IG, Fuente-Martin E, López-Noriega L, Mellado-Gil JM, Romero-Zerbo SY, Baquié M, Lachaud CC, Stifter K, Perdomo G, Bugliani M, De Tata V, Bosco D, Parnaud G, Pozo D, Hmadcha A, Florido JP, Toscano MG, de Haan P, Schoonjans K, Sánchez Palazón L, Marchetti P, Schirmbeck R, Martín-Montalvo A, Meda P, Soria B, Bermúdez-Silva FJ, St-Onge L, Gauthier BR.

Nat Commun. 2018 Apr 16;9(1):1488. doi: 10.1038/s41467-018-03943-0.

2.

The type 2 diabetes-associated HMG20A gene is mandatory for islet beta cell functional maturity.

Mellado-Gil JM, Fuente-Martín E, Lorenzo PI, Cobo-Vuilleumier N, López-Noriega L, Martín-Montalvo A, Gómez IGH, Ceballos-Chávez M, Gómez-Jaramillo L, Campos-Caro A, Romero-Zerbo SY, Rodríguez-Comas J, Servitja JM, Rojo-Martinez G, Hmadcha A, Soria B, Bugliani M, Marchetti P, Bérmudez-Silva FJ, Reyes JC, Aguilar-Diosdado M, Gauthier BR.

Cell Death Dis. 2018 Feb 15;9(3):279. doi: 10.1038/s41419-018-0272-z.

3.

GATA6 Controls Insulin Biosynthesis and Secretion in Adult β-Cells.

Villamayor L, Rodríguez-Seguel E, Araujo R, Carrasco M, Bru-Tarí E, Mellado-Gil JM, Gauthier BR, Martinelli P, Quesada I, Soria B, Martín F, Cano DA, Rojas A.

Diabetes. 2018 Mar;67(3):448-460. doi: 10.2337/db17-0364. Epub 2017 Dec 20.

4.

Levothyroxine enhances glucose clearance and blunts the onset of experimental type 1 diabetes mellitus in mice.

López-Noriega L, Cobo-Vuilleumier N, Narbona-Pérez ÁJ, Araujo-Garrido JL, Lorenzo PI, Mellado-Gil JM, Moreno JC, Gauthier BR, Martín-Montalvo A.

Br J Pharmacol. 2017 Nov;174(21):3795-3810. doi: 10.1111/bph.13975. Epub 2017 Sep 20.

PMID:
28800677
5.

PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.

Mellado-Gil JM, Jiménez-Moreno CM, Martin-Montalvo A, Alvarez-Mercado AI, Fuente-Martin E, Cobo-Vuilleumier N, Lorenzo PI, Bru-Tari E, Herrera-Gómez Ide G, López-Noriega L, Pérez-Florido J, Santoyo-López J, Spyrantis A, Meda P, Boehm BO, Quesada I, Gauthier BR.

Diabetologia. 2016 Apr;59(4):755-65. doi: 10.1007/s00125-016-3864-0. Epub 2016 Jan 26.

6.

PAX4 Defines an Expandable β-Cell Subpopulation in the Adult Pancreatic Islet.

Lorenzo PI, Fuente-Martín E, Brun T, Cobo-Vuilleumier N, Jimenez-Moreno CM, G Herrera Gomez I, López Noriega L, Mellado-Gil JM, Martin-Montalvo A, Soria B, Gauthier BR.

Sci Rep. 2015 Oct 27;5:15672. doi: 10.1038/srep15672.

7.

A Simple High Efficiency Intra-Islet Transduction Protocol Using Lentiviral Vectors.

Jimenez-Moreno CM, Herrera-Gomez IG, Lopez-Noriega L, Lorenzo PI, Cobo-Vuilleumier N, Fuente-Martin E, Mellado-Gil JM, Parnaud G, Bosco D, Gauthier BR, Martin-Montalvo A.

Curr Gene Ther. 2015;15(4):436-46.

8.

Hepatocyte growth factor/c-Met signaling is required for β-cell regeneration.

Alvarez-Perez JC, Ernst S, Demirci C, Casinelli GP, Mellado-Gil JM, Rausell-Palamos F, Vasavada RC, Garcia-Ocaña A.

Diabetes. 2014 Jan;63(1):216-23. doi: 10.2337/db13-0333. Epub 2013 Oct 2.

9.

Islet β-Cell Mass Preservation and Regeneration in Diabetes Mellitus: Four Factors with Potential Therapeutic Interest.

Mellado-Gil JM, Cobo-Vuilleumier N, Gauthier BR.

J Transplant. 2012;2012:230870. doi: 10.1155/2012/230870. Epub 2012 Aug 5.

10.

Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.

Velazquez-Garcia S, Valle S, Rosa TC, Takane KK, Demirci C, Alvarez-Perez JC, Mellado-Gil JM, Ernst S, Scott DK, Vasavada RC, Alonso LC, Garcia-Ocaña A.

Diabetes. 2011 Oct;60(10):2546-59. doi: 10.2337/db10-1783. Epub 2011 Sep 12.

11.

RB regulates pancreas development by stabilizing Pdx1.

Kim YC, Kim SY, Mellado-Gil JM, Yadav H, Neidermyer W, Kamaraju AK, Rane SG.

EMBO J. 2011 Apr 20;30(8):1563-76. doi: 10.1038/emboj.2011.57. Epub 2011 Mar 11.

12.

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis.

González-Pertusa JA, Dubé J, Valle SR, Rosa TC, Takane KK, Mellado-Gil JM, Perdomo G, Vasavada RC, García-Ocaña A.

Endocrinology. 2010 Apr;151(4):1487-98. doi: 10.1210/en.2009-0975. Epub 2010 Feb 22.

13.

Anti-proliferative effect of pro-inflammatory cytokines in cultured beta cells is associated with extracellular signal-regulated kinase 1/2 pathway inhibition: protective role of glucagon-like peptide -1.

Blandino-Rosano M, Perez-Arana G, Mellado-Gil JM, Segundo C, Aguilar-Diosdado M.

J Mol Endocrinol. 2008 Jul;41(1):35-44. doi: 10.1677/JME-07-0154. Epub 2008 May 16.

PMID:
18487229
14.

Protein kinase C-zeta activation markedly enhances beta-cell proliferation: an essential role in growth factor mediated beta-cell mitogenesis.

Vasavada RC, Wang L, Fujinaka Y, Takane KK, Rosa TC, Mellado-Gil JM, Friedman PA, Garcia-Ocaña A.

Diabetes. 2007 Nov;56(11):2732-43. Epub 2007 Aug 8.

15.

Differential analysis of donor characteristics for pancreas and islet transplantation.

Briones RM, Miranda JM, Mellado-Gil JM, Castro MJ, Gonzalez-Molina M, Cuesta-Muñoz AL, Alonso A, Frutos MA.

Transplant Proc. 2006 Oct;38(8):2579-81.

PMID:
17098008
16.

Internal assessment of a novel islet isolation facility in Spain.

Cuesta-Munoz AL, Briones RM, Mellado-Gil JM, Miranda JM, Castro MJ, Navarro A, Ruiz de Adana S, Alonso A, Gonzalez-Molina M, Soria B.

Transplant Proc. 2005 Oct;37(8):3404-6.

PMID:
16298608
17.

Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines.

Mellado-Gil JM, Aguilar-Diosdado M.

Biol Proced Online. 2005;7:162-71. Epub 2005 Nov 7.

18.

Supplemental Content

Loading ...
Support Center