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Items: 1 to 50 of 168

1.

Identification of Off-Patent Compounds That Present Antifungal Activity Against the Emerging Fungal Pathogen Candida auris.

de Oliveira HC, Monteiro MC, Rossi SA, Pemán J, Ruiz-Gaitán A, Mendes-Giannini MJS, Mellado E, Zaragoza O.

Front Cell Infect Microbiol. 2019 Apr 2;9:83. doi: 10.3389/fcimb.2019.00083. eCollection 2019.

2.

Two KTR Mannosyltransferases Are Responsible for the Biosynthesis of Cell Wall Mannans and Control Polarized Growth in Aspergillus fumigatus.

Henry C, Li J, Danion F, Alcazar-Fuoli L, Mellado E, Beau R, Jouvion G, Latgé JP, Fontaine T.

MBio. 2019 Feb 12;10(1). pii: e02647-18. doi: 10.1128/mBio.02647-18.

3.

Comparison of Two Highly Discriminatory Typing Methods to Analyze Aspergillus fumigatus Azole Resistance.

Garcia-Rubio R, Escribano P, Gomez A, Guinea J, Mellado E.

Front Microbiol. 2018 Jul 20;9:1626. doi: 10.3389/fmicb.2018.01626. eCollection 2018.

4.

Genome-Wide Comparative Analysis of Aspergillus fumigatus Strains: The Reference Genome as a Matter of Concern.

Garcia-Rubio R, Monzon S, Alcazar-Fuoli L, Cuesta I, Mellado E.

Genes (Basel). 2018 Jul 19;9(7). pii: E363. doi: 10.3390/genes9070363.

5.

Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms.

Garcia-Rubio R, Alcazar-Fuoli L, Monteiro MC, Monzon S, Cuesta I, Pelaez T, Mellado E.

Antimicrob Agents Chemother. 2018 May 25;62(6). pii: e00241-18. doi: 10.1128/AAC.00241-18. Print 2018 Jun.

6.

Could the determination of Aspergillus fumigatus mating type have prognostic value in invasive aspergillosis?

Monteiro MC, Garcia-Rubio R, Alcazar-Fuoli L, Peláez T, Mellado E.

Mycoses. 2018 Mar;61(3):172-178. doi: 10.1111/myc.12720. Epub 2017 Nov 22.

PMID:
29082564
7.

Development and Validation of a High-Resolution Melting Assay To Detect Azole Resistance in Aspergillus fumigatus.

Bernal-Martínez L, Gil H, Rivero-Menéndez O, Gago S, Cuenca-Estrella M, Mellado E, Alastruey-Izquierdo A.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01083-17. doi: 10.1128/AAC.01083-17. Print 2017 Dec.

8.

Mechanical and electrostatic experiments with dust particles collected in the inner coma of comet 67P by COSIMA onboard Rosetta.

Hilchenbach M, Fischer H, Langevin Y, Merouane S, Paquette J, Rynö J, Stenzel O, Briois C, Kissel J, Koch A, Schulz R, Silen J, Altobelli N, Baklouti D, Bardyn A, Cottin H, Engrand C, Fray N, Haerendel G, Henkel H, Höfner H, Hornung K, Lehto H, Mellado EM, Modica P, Le Roy L, Siljeström S, Steiger W, Thirkell L, Thomas R, Torkar K, Varmuza K, Zaprudin B; COSIMA team.

Philos Trans A Math Phys Eng Sci. 2017 Jul 13;375(2097). pii: 20160255. doi: 10.1098/rsta.2016.0255.

PMID:
28554975
9.

Triazole Resistance in Aspergillus Species: An Emerging Problem.

Garcia-Rubio R, Cuenca-Estrella M, Mellado E.

Drugs. 2017 Apr;77(6):599-613. doi: 10.1007/s40265-017-0714-4. Review.

PMID:
28236169
10.

Blood and tissue distribution of posaconazole in a rat model of invasive pulmonary aspergillosis.

Cendejas-Bueno E, Forastiero A, Ruiz I, Mellado E, Gavaldà J, Gomez-Lopez A.

Diagn Microbiol Infect Dis. 2017 Feb;87(2):112-117. doi: 10.1016/j.diagmicrobio.2016.10.010. Epub 2016 Oct 11.

PMID:
27889253
11.

A Straightforward Access to New Families of Lipophilic Polyphenols by Using Lipolytic Bacteria.

Sánchez-Barrionuevo L, González-Benjumea A, Escobar-Niño A, García MT, López Ó, Maya I, Fernández-Bolaños JG, Cánovas D, Mellado E.

PLoS One. 2016 Nov 17;11(11):e0166561. doi: 10.1371/journal.pone.0166561. eCollection 2016.

12.

Galactomannan enzyme immunoassay and quantitative Real Time PCR as tools to evaluate the exposure and response in a rat model of aspergillosis after posaconazole prophylaxis.

Cendejas-Bueno E, Forastiero A, Ruiz I, Mellado E, Buitrago MJ, Gavaldà J, Gomez-Lopez A.

Enferm Infecc Microbiol Clin. 2016 Nov;34(9):571-576. doi: 10.1016/j.eimc.2015.11.008. Epub 2016 Jan 21.

PMID:
26804792
13.

A New Aspergillus fumigatus Typing Method Based on Hypervariable Tandem Repeats Located within Exons of Surface Protein Coding Genes (TRESP).

Garcia-Rubio R, Gil H, Monteiro MC, Pelaez T, Mellado E.

PLoS One. 2016 Oct 4;11(10):e0163869. doi: 10.1371/journal.pone.0163869. eCollection 2016.

14.

Molecular identification, antifungal resistance and virulence of Cryptococcus neoformans and Cryptococcus deneoformans isolated in Seville, Spain.

Gago S, Serrano C, Alastruey-Izquierdo A, Cuesta I, Martín-Mazuelos E, Aller AI, Gómez-López A, Mellado E.

Mycoses. 2017 Jan;60(1):40-50. doi: 10.1111/myc.12543. Epub 2016 Sep 15.

PMID:
27633849
15.

Corrigendum to "First detection of Aspergillus fumigatus azole resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain" [New Microbes New Infect 6 (2015) 33-34].

Pelaez T, Monteiro MC, Garcia-Rubio R, Bouza E, Gomez-Lopez A, Mellado E.

New Microbes New Infect. 2016 May 6;13:59. doi: 10.1016/j.nmni.2016.04.009. eCollection 2016 Sep.

16.

Triazole Resistance in Aspergillus spp.: A Worldwide Problem?

Rivero-Menendez O, Alastruey-Izquierdo A, Mellado E, Cuenca-Estrella M.

J Fungi (Basel). 2016 Jul 4;2(3). pii: E21. doi: 10.3390/jof2030021. Review.

17.

Proposal for a unified nomenclature for target-site mutations associated with resistance to fungicides.

Mair W, Lopez-Ruiz F, Stammler G, Clark W, Burnett F, Hollomon D, Ishii H, Thind TS, Brown JK, Fraaije B, Cools H, Shaw M, Fillinger S, Walker AS, Mellado E, Schnabel G, Mehl A, Oliver RP.

Pest Manag Sci. 2016 Aug;72(8):1449-59. doi: 10.1002/ps.4301. Epub 2016 Jun 16.

18.

New applications for known drugs: Human glycogen synthase kinase 3 inhibitors as modulators of Aspergillus fumigatus growth.

Sebastián-Pérez V, Manoli MT, Pérez DI, Gil C, Mellado E, Martínez A, Espeso EA, Campillo NE.

Eur J Med Chem. 2016 Jun 30;116:281-289. doi: 10.1016/j.ejmech.2016.03.035. Epub 2016 Mar 25.

19.

Phylogenetic Profiling and Diversity of Bacterial Communities in the Death Valley, an Extreme Habitat in the Atacama Desert.

Piubeli F, de Lourdes Moreno M, Kishi LT, Henrique-Silva F, García MT, Mellado E.

Indian J Microbiol. 2015 Dec;55(4):392-9. doi: 10.1007/s12088-015-0539-3. Epub 2015 Jun 23.

20.

Fitness Studies of Azole-Resistant Strains of Aspergillus fumigatus.

Valsecchi I, Mellado E, Beau R, Raj S, Latgé JP.

Antimicrob Agents Chemother. 2015 Dec;59(12):7866-9. doi: 10.1128/AAC.01594-15. Epub 2015 Sep 28.

21.

In vivo efficacy of voriconazole and posaconazole therapy in a novel invertebrate model of Aspergillus fumigatus infection.

Forastiero A, Bernal-Martínez L, Mellado E, Cendejas E, Gomez-Lopez A.

Int J Antimicrob Agents. 2015 Nov;46(5):511-7. doi: 10.1016/j.ijantimicag.2015.07.007. Epub 2015 Aug 17.

PMID:
26358971
22.

Rapid development of Candida krusei echinocandin resistance during caspofungin therapy.

Forastiero A, Garcia-Gil V, Rivero-Menendez O, Garcia-Rubio R, Monteiro MC, Alastruey-Izquierdo A, Jordan R, Agorio I, Mellado E.

Antimicrob Agents Chemother. 2015 Nov;59(11):6975-82. doi: 10.1128/AAC.01005-15. Epub 2015 Aug 31.

23.

First detection of Aspergillus fumigatus azole-resistant strain due to Cyp51A TR46/Y121F/T289A in an azole-naive patient in Spain.

Pelaez T, Monteiro MC, Garcia-Rubio R, Bouza E, Gomez-Lopez A, Mellado E.

New Microbes New Infect. 2015 Apr 20;6:33-4. doi: 10.1016/j.nmni.2015.04.005. eCollection 2015 Jul. Erratum in: New Microbes New Infect. 2016 Sep;13:59.

24.

An alternative host model of a mixed fungal infection by azole susceptible and resistant Aspergillus spp strains.

Alcazar-Fuoli L, Buitrago M, Gomez-Lopez A, Mellado E.

Virulence. 2015;6(4):376-84. doi: 10.1080/21505594.2015.1025192.

25.

Hitting the caspofungin salvage pathway of human-pathogenic fungi with the novel lasso peptide humidimycin (MDN-0010).

Valiante V, Monteiro MC, Martín J, Altwasser R, El Aouad N, González I, Kniemeyer O, Mellado E, Palomo S, de Pedro N, Pérez-Victoria I, Tormo JR, Vicente F, Reyes F, Genilloud O, Brakhage AA.

Antimicrob Agents Chemother. 2015 Sep;59(9):5145-53. doi: 10.1128/AAC.00683-15. Epub 2015 Jun 8.

26.

Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus.

van der Linden JW, Arendrup MC, Warris A, Lagrou K, Pelloux H, Hauser PM, Chryssanthou E, Mellado E, Kidd SE, Tortorano AM, Dannaoui E, Gaustad P, Baddley JW, Uekötter A, Lass-Flörl C, Klimko N, Moore CB, Denning DW, Pasqualotto AC, Kibbler C, Arikan-Akdagli S, Andes D, Meletiadis J, Naumiuk L, Nucci M, Melchers WJ, Verweij PE.

Emerg Infect Dis. 2015 Jun;21(6):1041-4. doi: 10.3201/eid2106.140717.

27.

Genetic relatedness versus biological compatibility between Aspergillus fumigatus and related species.

Sugui JA, Peterson SW, Figat A, Hansen B, Samson RA, Mellado E, Cuenca-Estrella M, Kwon-Chung KJ.

J Clin Microbiol. 2014 Oct;52(10):3707-21. doi: 10.1128/JCM.01704-14. Epub 2014 Aug 6.

28.

Selection and characterization of biofuel-producing environmental bacteria isolated from vegetable oil-rich wastes.

Escobar-Niño A, Luna C, Luna D, Marcos AT, Cánovas D, Mellado E.

PLoS One. 2014 Aug 6;9(8):e104063. doi: 10.1371/journal.pone.0104063. eCollection 2014.

29.

Deciphering the role of the chitin synthase families 1 and 2 in the in vivo and in vitro growth of Aspergillus fumigatus by multiple gene targeting deletion.

Muszkieta L, Aimanianda V, Mellado E, Gribaldo S, Alcàzar-Fuoli L, Szewczyk E, Prevost MC, Latgé JP.

Cell Microbiol. 2014 Dec;16(12):1784-805. doi: 10.1111/cmi.12326. Epub 2014 Aug 15.

PMID:
24946720
30.

Ribosomic DNA intergenic spacer 1 region is useful when identifying Candida parapsilosis spp. complex based on high-resolution melting analysis.

Gago S, Alastruey-Izquierdo A, Marconi M, Buitrago MJ, Kerhornou A, Kersey PJ, Mellado E, Cuenca-Estrella M, Rodríguez-Tudela JL, Cuesta I.

Med Mycol. 2014 Jul;52(5):472-81. doi: 10.1093/mmy/myu009. Epub 2014 May 20.

PMID:
24847037
31.

Current status of antifungal resistance and its impact on clinical practice.

Alcazar-Fuoli L, Mellado E.

Br J Haematol. 2014 Aug;166(4):471-84. doi: 10.1111/bjh.12896. Epub 2014 Apr 18. Review.

PMID:
24749533
32.

An invertebrate model to evaluate virulence in Aspergillus fumigatus: the role of azole resistance.

Gomez-Lopez A, Forastiero A, Cendejas-Bueno E, Gregson L, Mellado E, Howard SJ, Livermore JL, Hope WW, Cuenca-Estrella M.

Med Mycol. 2014 Apr;52(3):311-9. doi: 10.1093/mmy/myt022. Epub 2014 Feb 4.

PMID:
24577012
33.

Polyphasic characterization of fungal isolates from a published case of invasive aspergillosis reveals misidentification of Aspergillus felis as Aspergillus viridinutans.

Alvarez-Pérez S, Mellado E, Serrano D, Blanco JL, Garcia ME, Kwon M, Muñoz P, Cuenca-Estrella M, Bouza E, Peláez T.

J Med Microbiol. 2014 Apr;63(Pt 4):617-9. doi: 10.1099/jmm.0.068502-0. Epub 2014 Jan 27. No abstract available.

PMID:
24469682
34.

The ZrfC alkaline zinc transporter is required for Aspergillus fumigatus virulence and its growth in the presence of the Zn/Mn-chelating protein calprotectin.

Amich J, Vicentefranqueira R, Mellado E, Ruiz-Carmuega A, Leal F, Calera JA.

Cell Microbiol. 2014 Apr;16(4):548-64. doi: 10.1111/cmi.12238. Epub 2013 Dec 4.

PMID:
24245710
35.

Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis virulence in the non-conventional host Galleria mellonella.

Gago S, García-Rodas R, Cuesta I, Mellado E, Alastruey-Izquierdo A.

Virulence. 2014 Feb 15;5(2):278-85. doi: 10.4161/viru.26973. Epub 2013 Nov 5.

36.

Population-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study).

Alastruey-Izquierdo A, Mellado E, Peláez T, Pemán J, Zapico S, Alvarez M, Rodríguez-Tudela JL, Cuenca-Estrella M; FILPOP Study Group.

Antimicrob Agents Chemother. 2013 Sep;57(9):4604. doi: 10.1128/AAC.01287-13. No abstract available.

37.

Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications.

Forastiero A, Mesa-Arango AC, Alastruey-Izquierdo A, Alcazar-Fuoli L, Bernal-Martinez L, Pelaez T, Lopez JF, Grimalt JO, Gomez-Lopez A, Cuesta I, Zaragoza O, Mellado E.

Antimicrob Agents Chemother. 2013 Oct;57(10):4769-81. doi: 10.1128/AAC.00477-13. Epub 2013 Jul 22.

38.

Population-based survey of filamentous fungi and antifungal resistance in Spain (FILPOP Study).

Alastruey-Izquierdo A, Mellado E, Peláez T, Pemán J, Zapico S, Alvarez M, Rodríguez-Tudela JL, Cuenca-Estrella M; FILPOP Study Group.

Antimicrob Agents Chemother. 2013 Jul;57(7):3380-7. doi: 10.1128/AAC.00383-13. Epub 2013 May 13. Erratum in: Antimicrob Agents Chemother. 2013 Sep;57(9):4604. Antimicrob Agents Chemother. 2013 Sep;57(9):4604.

39.

Ergosterol biosynthesis in Aspergillus fumigatus: its relevance as an antifungal target and role in antifungal drug resistance.

Alcazar-Fuoli L, Mellado E.

Front Microbiol. 2013 Jan 10;3:439. doi: 10.3389/fmicb.2012.00439. eCollection 2012.

40.

Phenol degradation by halophilic bacteria isolated from hypersaline environments.

Bonfá MR, Grossman MJ, Piubeli F, Mellado E, Durrant LR.

Biodegradation. 2013 Sep;24(5):699-709. doi: 10.1007/s10532-012-9617-y. Epub 2013 Jan 5.

PMID:
23292008
41.

Halophilic bacteria as a source of novel hydrolytic enzymes.

de Lourdes Moreno M, Pérez D, García MT, Mellado E.

Life (Basel). 2013 Jan 10;3(1):38-51. doi: 10.3390/life3010038. Review.

42.

Current section and species complex concepts in Aspergillus: recommendations for routine daily practice.

Alastruey-Izquierdo A, Mellado E, Cuenca-Estrella M.

Ann N Y Acad Sci. 2012 Dec;1273:18-24. doi: 10.1111/j.1749-6632.2012.06822.x.

PMID:
23230833
43.

The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast.

Mesa-Arango AC, Forastiero A, Bernal-Martínez L, Cuenca-Estrella M, Mellado E, Zaragoza O.

Med Mycol. 2013 Jul;51(5):461-72. doi: 10.3109/13693786.2012.737031. Epub 2012 Nov 21.

PMID:
23170962
44.

Invasive aspergillosis caused by cryptic Aspergillus species: a report of two consecutive episodes in a patient with leukaemia.

Peláez T, Alvarez-Pérez S, Mellado E, Serrano D, Valerio M, Blanco JL, Garcia ME, Muñoz P, Cuenca-Estrella M, Bouza E.

J Med Microbiol. 2013 Mar;62(Pt 3):474-8. doi: 10.1099/jmm.0.044867-0. Epub 2012 Nov 15.

PMID:
23161769
45.

Breakthrough pulmonary Aspergillus fumigatus infection with multiple triazole resistance in a Spanish patient with chronic myeloid leukemia.

Mellado E, De La Camara R, Buendía B, Rodriguez-Tudela JL, Cuenca-Estrella M.

Rev Iberoam Micol. 2013 Jan 3;30(1):64-8. doi: 10.1016/j.riam.2012.09.002. Epub 2012 Sep 15.

PMID:
22986228
46.

Analysis and characterization of cultivable extremophilic hydrolytic bacterial community in heavy-metal-contaminated soils from the Atacama Desert and their biotechnological potentials.

Moreno ML, Piubeli F, Bonfá MR, García MT, Durrant LR, Mellado E.

J Appl Microbiol. 2012 Sep;113(3):550-9. doi: 10.1111/j.1365-2672.2012.05366.x. Epub 2012 Jul 24.

47.

Carotenoids' production from halophilic bacteria.

de Lourdes Moreno M, Sánchez-Porro C, García MT, Mellado E.

Methods Mol Biol. 2012;892:207-17. doi: 10.1007/978-1-61779-879-5_12.

PMID:
22623305
48.

Identification of amino acids involved in the hydrolytic activity of lipase LipBL from Marinobacter lipolyticus.

Pérez D, Kovacic F, Wilhelm S, Jaeger KE, García MT, Ventosa A, Mellado E.

Microbiology. 2012 Aug;158(Pt 8):2192-203. doi: 10.1099/mic.0.058792-0. Epub 2012 May 18.

PMID:
22609754
49.

Resistance to voriconazole due to a G448S substitution in Aspergillus fumigatus in a patient with cerebral aspergillosis.

Pelaez T, Gijón P, Bunsow E, Bouza E, Sánchez-Yebra W, Valerio M, Gama B, Cuenca-Estrella M, Mellado E.

J Clin Microbiol. 2012 Jul;50(7):2531-4. doi: 10.1128/JCM.00329-12. Epub 2012 May 9.

50.

Zygomycosis caused by Rhizopus microsporus and Rhizopus oryzae in Madhya Pradesh (M.P.) Central India: a report of two cases.

Nawange SR, Singh SM, Naidu J, Jain S, Nagpal T, Behrani DS, Mellado E, Tudela JL.

Mycopathologia. 2012 Aug;174(2):171-6. doi: 10.1007/s11046-012-9532-0. Epub 2012 Mar 23.

PMID:
22437261

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