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Items: 32


Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.

Shetty M, Noguchi C, Wilson S, Martinez E, Shiozaki K, Sell C, Mell JC, Noguchi E.

Aging Cell. 2019 Dec 12:e13068. doi: 10.1111/acel.13068. [Epub ahead of print]


Exploring thematic structure and predicted functionality of 16S rRNA amplicon data.

Woloszynek S, Mell JC, Zhao Z, Simpson G, O'Connor MP, Rosen GL.

PLoS One. 2019 Dec 11;14(12):e0219235. doi: 10.1371/journal.pone.0219235. eCollection 2019.


Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients.

Sullivan NT, Dampier W, Chung CH, Allen AG, Atkins A, Pirrone V, Homan G, Passic S, Williams J, Zhong W, Kercher K, Desimone M, Li L, C Antell G, Mell JC, Ehrlich GD, Szep Z, Jacobson JM, Nonnemacher MR, Wigdahl B.

Sci Rep. 2019 Nov 19;9(1):17088. doi: 10.1038/s41598-019-52353-9.


Genome rearrangements induce biofilm formation in Escherichia coli C - an old model organism with a new application in biofilm research.

Król JE, Hall DC Jr, Balashov S, Pastor S, Sibert J, McCaffrey J, Lang S, Ehrlich RL, Earl J, Mell JC, Xiao M, Ehrlich GD.

BMC Genomics. 2019 Oct 22;20(1):767. doi: 10.1186/s12864-019-6165-4.


Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG.

Kumova OK, Fike AJ, Thayer JL, Nguyen LT, Mell JC, Pascasio J, Stairiker C, Leon LG, Katsikis PD, Carey AJ.

PLoS Pathog. 2019 Oct 11;15(10):e1008072. doi: 10.1371/journal.ppat.1008072. eCollection 2019 Oct.


Species-level bacterial community profiling of the healthy sinonasal microbiome using Pacific Biosciences sequencing of full-length 16S rRNA genes.

Earl JP, Adappa ND, Krol J, Bhat AS, Balashov S, Ehrlich RL, Palmer JN, Workman AD, Blasetti M, Sen B, Hammond J, Cohen NA, Ehrlich GD, Mell JC.

Microbiome. 2018 Oct 23;6(1):190. doi: 10.1186/s40168-018-0569-2.


Antagonistic Pleiotropy in the Bifunctional Surface Protein FadL (OmpP1) during Adaptation of Haemophilus influenzae to Chronic Lung Infection Associated with Chronic Obstructive Pulmonary Disease.

Moleres J, Fernández-Calvet A, Ehrlich RL, Martí S, Pérez-Regidor L, Euba B, Rodríguez-Arce I, Balashov S, Cuevas E, Liñares J, Ardanuy C, Martín-Santamaría S, Ehrlich GD, Mell JC, Garmendia J.

MBio. 2018 Sep 25;9(5). pii: e01176-18. doi: 10.1128/mBio.01176-18.


Interaction between the microbiome and TP53 in human lung cancer.

Greathouse KL, White JR, Vargas AJ, Bliskovsky VV, Beck JA, von Muhlinen N, Polley EC, Bowman ED, Khan MA, Robles AI, Cooks T, Ryan BM, Padgett N, Dzutsev AH, Trinchieri G, Pineda MA, Bilke S, Meltzer PS, Hokenstad AN, Stickrod TM, Walther-Antonio MR, Earl JP, Mell JC, Krol JE, Balashov SV, Bhat AS, Ehrlich GD, Valm A, Deming C, Conlan S, Oh J, Segre JA, Harris CC.

Genome Biol. 2018 Aug 24;19(1):123. doi: 10.1186/s13059-018-1501-6.


Broad-Spectrum and Personalized Guide RNAs for CRISPR/Cas9 HIV-1 Therapeutics.

Dampier W, Sullivan NT, Mell JC, Pirrone V, Ehrlich GD, Chung CH, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams JW, Szep Z, Khalili K, Jacobson JM, Nonnemacher MR, Wigdahl B.

AIDS Res Hum Retroviruses. 2018 Nov;34(11):950-960. doi: 10.1089/AID.2017.0274. Epub 2018 Aug 27.


Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants.

Dampier W, Sullivan NT, Chung CH, Mell JC, Nonnemacher MR, Wigdahl B.

Sci Rep. 2017 Oct 31;7(1):14413. doi: 10.1038/s41598-017-12612-z.


Phenotypic diversity and genotypic flexibility of Burkholderia cenocepacia during long-term chronic infection of cystic fibrosis lungs.

Lee AH, Flibotte S, Sinha S, Paiero A, Ehrlich RL, Balashov S, Ehrlich GD, Zlosnik JE, Mell JC, Nislow C.

Genome Res. 2017 Apr;27(4):650-662. doi: 10.1101/gr.213363.116. Epub 2017 Mar 21.


Complete Genome Sequence of Aggregatibacter actinomycetemcomitans Strain IDH781.

May AC, Ehrlich RL, Balashov S, Ehrlich GD, Shanmugam M, Fine DH, Ramasubbu N, Mell JC, Cugini C.

Genome Announc. 2016 Nov 10;4(6). pii: e01285-16. doi: 10.1128/genomeA.01285-16.


Mitochondrial Haplogroup Influences Motor Function in Long-Term HIV-1-Infected Individuals.

Azar A, Devlin K, Mell JC, Giovannetti T, Pirrone V, Nonnemacher MR, Passic S, Kercher K, Williams JW, Jacobson JM, Wigdahl B, Dampier W, Libon DJ, Sell C.

PLoS One. 2016 Oct 6;11(10):e0163772. doi: 10.1371/journal.pone.0163772. eCollection 2016.


Transformed Recombinant Enrichment Profiling Rapidly Identifies HMW1 as an Intracellular Invasion Locus in Haemophilus influenza.

Mell JC, Viadas C, Moleres J, Sinha S, Fernández-Calvet A, Porsch EA, St Geme JW 3rd, Nislow C, Redfield RJ, Garmendia J.

PLoS Pathog. 2016 Apr 28;12(4):e1005576. doi: 10.1371/journal.ppat.1005576. eCollection 2016 Apr. Erratum in: PLoS Pathog. 2016 May;12(5):e1005681.


Engineering Human Microbiota: Influencing Cellular and Community Dynamics for Therapeutic Applications.

Woloszynek S, Pastor S, Mell JC, Nandi N, Sokhansanj B, Rosen GL.

Int Rev Cell Mol Biol. 2016;324:67-124. doi: 10.1016/bs.ircmb.2016.01.003. Epub 2016 Mar 9. Review.


Identification and Characterization of msf, a Novel Virulence Factor in Haemophilus influenzae.

Kress-Bennett JM, Hiller NL, Eutsey RA, Powell E, Longwell MJ, Hillman T, Blackwell T, Byers B, Mell JC, Post JC, Hu FZ, Ehrlich GD, Janto BA.

PLoS One. 2016 Mar 15;11(3):e0149891. doi: 10.1371/journal.pone.0149891. eCollection 2016.


Transcriptome-Wide Analysis of Hepatitis B Virus-Mediated Changes to Normal Hepatocyte Gene Expression.

Lamontagne J, Mell JC, Bouchard MJ.

PLoS Pathog. 2016 Feb 18;12(2):e1005438. doi: 10.1371/journal.ppat.1005438. eCollection 2016 Feb.


Complete Genome Sequence of Haemophilus influenzae Strain 375 from the Middle Ear of a Pediatric Patient with Otitis Media.

Mell JC, Sinha S, Balashov S, Viadas C, Grassa CJ, Ehrlich GD, Nislow C, Redfield RJ, Garmendia J.

Genome Announc. 2014 Dec 4;2(6). pii: e01245-14. doi: 10.1128/genomeA.01245-14.


Characterization of nontypable Haemophilus influenzae isolates recovered from adult patients with underlying chronic lung disease reveals genotypic and phenotypic traits associated with persistent infection.

Garmendia J, Viadas C, Calatayud L, Mell JC, Martí-Lliteras P, Euba B, Llobet E, Gil C, Bengoechea JA, Redfield RJ, Liñares J.

PLoS One. 2014 May 13;9(5):e97020. doi: 10.1371/journal.pone.0097020. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e107686.


Extensive cotransformation of natural variation into chromosomes of naturally competent Haemophilus influenzae.

Mell JC, Lee JY, Firme M, Sinha S, Redfield RJ.

G3 (Bethesda). 2014 Apr 16;4(4):717-31. doi: 10.1534/g3.113.009597.


Natural competence and the evolution of DNA uptake specificity.

Mell JC, Redfield RJ.

J Bacteriol. 2014 Apr;196(8):1471-83. doi: 10.1128/JB.01293-13. Epub 2014 Jan 31. Review.


Seventeen Sxy-dependent cyclic AMP receptor protein site-regulated genes are needed for natural transformation in Haemophilus influenzae.

Sinha S, Mell JC, Redfield RJ.

J Bacteriol. 2012 Oct;194(19):5245-54. doi: 10.1128/JB.00671-12. Epub 2012 Jul 20.


Defining the DNA uptake specificity of naturally competent Haemophilus influenzae cells.

Mell JC, Hall IM, Redfield RJ.

Nucleic Acids Res. 2012 Sep 1;40(17):8536-49. Epub 2012 Jun 29.


Natural transformation of Gallibacterium anatis.

Kristensen BM, Sinha S, Boyce JD, Bojesen AM, Mell JC, Redfield RJ.

Appl Environ Microbiol. 2012 Jul;78(14):4914-22. doi: 10.1128/AEM.00412-12. Epub 2012 May 11.


Molecular evolution under increasing transposable element burden in Drosophila: a speed limit on the evolutionary arms race.

Castillo DM, Mell JC, Box KS, Blumenstiel JP.

BMC Evol Biol. 2011 Sep 14;11:258. doi: 10.1186/1471-2148-11-258.


Transformation of natural genetic variation into Haemophilus influenzae genomes.

Mell JC, Shumilina S, Hall IM, Redfield RJ.

PLoS Pathog. 2011 Jul;7(7):e1002151. doi: 10.1371/journal.ppat.1002151. Epub 2011 Jul 28.


Superhelical duplex destabilization and the recombination position effect.

Sershen CL, Mell JC, Madden SM, Benham CJ.

PLoS One. 2011;6(6):e20798. doi: 10.1371/journal.pone.0020798. Epub 2011 Jun 9.


Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome.

Quinlan AR, Clark RA, Sokolova S, Leibowitz ML, Zhang Y, Hurles ME, Mell JC, Hall IM.

Genome Res. 2010 May;20(5):623-35. doi: 10.1101/gr.102970.109. Epub 2010 Mar 22.


Cooperative interactions between pairs of homologous chromatids during meiosis in Saccharomyces cerevisiae.

Mell JC, Komachi K, Hughes O, Burgess S.

Genetics. 2008 Jun;179(2):1125-7. doi: 10.1534/genetics.108.088567.


Sites of recombination are local determinants of meiotic homolog pairing in Saccharomyces cerevisiae.

Mell JC, Wienholz BL, Salem A, Burgess SM.

Genetics. 2008 Jun;179(2):773-84. doi: 10.1534/genetics.107.077727. Epub 2008 May 27.


Analysis of close stable homolog juxtaposition during meiosis in mutants of Saccharomyces cerevisiae.

Lui DY, Peoples-Holst TL, Mell JC, Wu HY, Dean EW, Burgess SM.

Genetics. 2006 Jul;173(3):1207-22. Epub 2006 Apr 30.


Art and the brain: the influence of frontotemporal dementia on an accomplished artist.

Mell JC, Howard SM, Miller BL.

Neurology. 2003 May 27;60(10):1707-10.


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