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Items: 29


Bortezomib-induced aerobic glycolysis contributes to chemotherapy-induced painful peripheral neuropathy.

Ludman T, Melemedjian OK.

Mol Pain. 2019 Jan-Dec;15:1744806919837429. doi: 10.1177/1744806919837429.


The MNK-eIF4E Signaling Axis Contributes to Injury-Induced Nociceptive Plasticity and the Development of Chronic Pain.

Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, Dussor G, Sonenberg N, Price TJ.

J Neurosci. 2017 Aug 2;37(31):7481-7499. doi: 10.1523/JNEUROSCI.0220-17.2017. Epub 2017 Jul 3.


Peripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia.

Auh QS, Chun YH, Melemedjian OK, Zhang Y, Ro JY.

Brain Res Bull. 2016 Jul;125:211-7. doi: 10.1016/j.brainresbull.2016.07.009. Epub 2016 Jul 20.


A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.

François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R.

Pain. 2015 Jul;156(7):1247-64. doi: 10.1097/j.pain.0000000000000147.


Translational control of chronic pain.

Melemedjian OK, Khoutorsky A.

Prog Mol Biol Transl Sci. 2015;131:185-213. doi: 10.1016/bs.pmbts.2014.11.006. Epub 2015 Jan 30. Review.


The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth.

Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R.

Front Cell Neurosci. 2014 Jul 24;8:196. doi: 10.3389/fncel.2014.00196. eCollection 2014.


Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity.

Melemedjian OK, Tillu DV, Moy JK, Asiedu MN, Mandell EK, Ghosh S, Dussor G, Price TJ.

Mol Pain. 2014 Jul 4;10:45. doi: 10.1186/1744-8069-10-45.


Dural fibroblasts play a potential role in headache pathophysiology.

Wei X, Melemedjian OK, Ahn DD, Weinstein N, Dussor G.

Pain. 2014 Jul;155(7):1238-44. doi: 10.1016/j.pain.2014.03.013. Epub 2014 Mar 20.


Bidirectional regulation of P body formation mediated by eIF4F complex formation in sensory neurons.

Melemedjian OK, Mejia GL, Lepow TS, Zoph OK, Price TJ.

Neurosci Lett. 2014 Mar 20;563:169-74. doi: 10.1016/j.neulet.2013.09.048. Epub 2013 Sep 27.


Protein Z, an anticoagulant protein with expanding role in reproductive biology.

Almawi WY, Al-Shaikh FS, Melemedjian OK, Almawi AW.

Reproduction. 2013 Jun 27;146(2):R73-80. doi: 10.1530/REP-13-0072. Print 2013 Aug. Review.


mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK.

Melemedjian OK, Khoutorsky A, Sorge RE, Yan J, Asiedu MN, Valdez A, Ghosh S, Dussor G, Mogil JS, Sonenberg N, Price TJ.

Pain. 2013 Jul;154(7):1080-91. doi: 10.1016/j.pain.2013.03.021. Epub 2013 Mar 15.


BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state.

Melemedjian OK, Tillu DV, Asiedu MN, Mandell EK, Moy JK, Blute VM, Taylor CJ, Ghosh S, Price TJ.

Mol Pain. 2013 Mar 20;9:12. doi: 10.1186/1744-8069-9-12.


Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain.

King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F.

Pain. 2012 Jun;153(6):1263-73. doi: 10.1016/j.pain.2012.03.006. Epub 2012 Apr 4.


Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6).

Yan J, Melemedjian OK, Price TJ, Dussor G.

Mol Pain. 2012 Jan 24;8:6. doi: 10.1186/1744-8069-8-6.


Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain.

Tillu DV, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ.

Mol Pain. 2012 Jan 23;8:5. doi: 10.1186/1744-8069-8-5.


Dendritic spine plasticity as an underlying mechanism of neuropathic pain: commentary on Tan et al.

Melemedjian OK, Price TJ.

Exp Neurol. 2012 Feb;233(2):740-4. doi: 10.1016/j.expneurol.2011.11.016. Epub 2011 Nov 19. No abstract available.


Fragile X mental retardation protein (FMRP) and the spinal sensory system.

Price TJ, Melemedjian OK.

Results Probl Cell Differ. 2012;54:41-59. doi: 10.1007/978-3-642-21649-7_4.


Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain.

Melemedjian OK, Asiedu MN, Tillu DV, Sanoja R, Yan J, Lark A, Khoutorsky A, Johnson J, Peebles KA, Lepow T, Sonenberg N, Dussor G, Price TJ.

Mol Pain. 2011 Sep 21;7:70. doi: 10.1186/1744-8069-7-70.


Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization.

Asiedu MN, Tillu DV, Melemedjian OK, Shy A, Sanoja R, Bodell B, Ghosh S, Porreca F, Price TJ.

J Neurosci. 2011 May 4;31(18):6646-53. doi: 10.1523/JNEUROSCI.6286-10.2011.


IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex.

Melemedjian OK, Asiedu MN, Tillu DV, Peebles KA, Yan J, Ertz N, Dussor GO, Price TJ.

J Neurosci. 2010 Nov 10;30(45):15113-23. doi: 10.1523/JNEUROSCI.3947-10.2010.


Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist.

Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F.

Pain. 2010 Nov;151(2):257-65. doi: 10.1016/j.pain.2010.05.022. Epub 2010 Jul 4.


Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: implications for chemical-induced peripheral sensory neuropathies.

Jimenez-Andrade JM, Herrera MB, Ghilardi JR, Vardanyan M, Melemedjian OK, Mantyh PW.

Mol Pain. 2008 Mar 19;4:10. doi: 10.1186/1744-8069-4-10.


On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis.

Almawi WY, Melemedjian OK, Jaoude MM.

J Leukoc Biol. 2004 Jul;76(1):7-14. Epub 2004 Apr 9. Review.


Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids.

Almawi WY, Melemedjian OK.

J Mol Endocrinol. 2002 Apr;28(2):69-78. Review.


Clinical and mechanistic differences between FK506 (tacrolimus) and cyclosporin A.

Almawi WY, Melemedjian OK.

Nephrol Dial Transplant. 2000 Dec;15(12):1916-8. Review. No abstract available.


An alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile.

Almawi WY, Melemedjian OK, Rieder MJ.

Clin Transplant. 1999 Oct;13(5):365-74. Review.


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