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Items: 1 to 50 of 68

1.

Population genomics of grey wolves and wolf-like canids in North America.

Sinding MS, Gopalakrishan S, Vieira FG, Samaniego Castruita JA, Raundrup K, Heide Jørgensen MP, Meldgaard M, Petersen B, Sicheritz-Ponten T, Mikkelsen JB, Marquard-Petersen U, Dietz R, Sonne C, Dalén L, Bachmann L, Wiig Ø, Hansen AJ, Gilbert MTP.

PLoS Genet. 2018 Nov 12;14(11):e1007745. doi: 10.1371/journal.pgen.1007745. eCollection 2018 Nov.

2.

Greenland sled dogs at risk of extinction.

Sonne C, Langebæk R, Dietz R, Andersen-Ranberg E, Houser G, Hansen AJ, Sinding MS, Olsen MT, Egevang C, Gilbert MTP, Meldgaard M.

Science. 2018 Jun 8;360(6393):1080. doi: 10.1126/science.aat9578. No abstract available.

PMID:
29880678
3.

DNA evidence of bowhead whale exploitation by Greenlandic Paleo-Inuit 4,000 years ago.

Seersholm FV, Pedersen MW, Søe MJ, Shokry H, Mak SS, Ruter A, Raghavan M, Fitzhugh W, Kjær KH, Willerslev E, Meldgaard M, Kapel CM, Hansen AJ.

Nat Commun. 2016 Nov 8;7:13389. doi: 10.1038/ncomms13389.

4.

Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke.

Clausen BH, Lambertsen KL, Dagnæs-Hansen F, Babcock AA, von Linstow CU, Meldgaard M, Kristensen BW, Deierborg T, Finsen B.

Acta Neuropathol. 2016 May;131(5):775-91. doi: 10.1007/s00401-016-1541-5. Epub 2016 Feb 9.

5.

The genetic prehistory of the New World Arctic.

Raghavan M, DeGiorgio M, Albrechtsen A, Moltke I, Skoglund P, Korneliussen TS, Grønnow B, Appelt M, Gulløv HC, Friesen TM, Fitzhugh W, Malmström H, Rasmussen S, Olsen J, Melchior L, Fuller BT, Fahrni SM, Stafford T Jr, Grimes V, Renouf MA, Cybulski J, Lynnerup N, Lahr MM, Britton K, Knecht R, Arneborg J, Metspalu M, Cornejo OE, Malaspinas AS, Wang Y, Rasmussen M, Raghavan V, Hansen TV, Khusnutdinova E, Pierre T, Dneprovsky K, Andreasen C, Lange H, Hayes MG, Coltrain J, Spitsyn VA, Götherström A, Orlando L, Kivisild T, Villems R, Crawford MH, Nielsen FC, Dissing J, Heinemeier J, Meldgaard M, Bustamante C, O'Rourke DH, Jakobsson M, Gilbert MT, Nielsen R, Willerslev E.

Science. 2014 Aug 29;345(6200):1255832. doi: 10.1126/science.1255832.

6.

No effect of ablation of surfactant protein-D on acute cerebral infarction in mice.

Lambertsen KL, Østergaard K, Clausen BH, Hansen S, Stenvang J, Thorsen SB, Meldgaard M, Kristensen BW, Hansen PB, Sorensen GL, Finsen B.

J Neuroinflammation. 2014 Jul 19;11:123. doi: 10.1186/1742-2094-11-123.

7.

Individuals with complete filaggrin deficiency may have an increased risk of squamous cell carcinoma.

Kaae J, Szecsi PB, Meldgaard M, Espersen ML, Stender S, Johansen JD, Bandier J, Thyssen JP, Menné T, Nielsen SL, Høgdall E, Balslev E, Skov L.

Br J Dermatol. 2014 Jun;170(6):1380-1. doi: 10.1111/bjd.12911. No abstract available.

PMID:
24641578
8.

Filaggrin loss-of-function mutations and incident cancer: a population-based study.

Skaaby T, Husemoen LL, Thyssen JP, Meldgaard M, Thuesen BH, Pisinger C, Jørgensen T, Carlsen K, Johansen JD, Menné T, Szecsi PB, Stender S, Linneberg A.

Br J Dermatol. 2014 Dec;171(6):1407-14. doi: 10.1111/bjd.12969. Epub 2014 Nov 9.

PMID:
24628370
9.

Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.

Joensen UN, Jørgensen N, Meldgaard M, Frederiksen H, Andersson AM, Menné T, Johansen JD, Carlsen BC, Stender S, Szecsi PB, Skakkebæk NE, Rajpert-De Meyts E, Thyssen JP.

Environ Health Perspect. 2014 Apr;122(4):345-50. doi: 10.1289/ehp.1306720. Epub 2014 Jan 3.

10.

No association between loss-of-function mutations in filaggrin and diabetes, cardiovascular disease, and all-cause mortality.

Husemoen LL, Skaaby T, Jørgensen T, Thyssen JP, Meldgaard M, Szecsi PB, Stender S, Johansen JD, Linneberg A.

PLoS One. 2013 Dec 18;8(12):e84293. doi: 10.1371/journal.pone.0084293. eCollection 2013.

11.

Investigating the causal effect of vitamin D on serum adiponectin using a Mendelian randomization approach.

Husemoen LL, Skaaby T, Martinussen T, Jørgensen T, Thuesen BH, Kistorp C, Jeppesen J, Thyssen JP, Meldgaard M, Szecsi PB, Fenger M, Linneberg A.

Eur J Clin Nutr. 2014 Feb;68(2):189-95. doi: 10.1038/ejcn.2013.233. Epub 2013 Nov 13.

PMID:
24219894
12.

Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern.

Hagedorn PH, Yakimov V, Ottosen S, Kammler S, Nielsen NF, Høg AM, Hedtjärn M, Meldgaard M, Møller MR, Orum H, Koch T, Lindow M.

Nucleic Acid Ther. 2013 Oct;23(5):302-10. doi: 10.1089/nat.2013.0436. Epub 2013 Aug 16.

13.

Filaggrin compound heterozygous patients carry mutations in trans position.

Carlsen BC, Meldgaard M, Johansen JD, Thyssen JP, Menné T, Szecsi PB, Stender S.

Exp Dermatol. 2013 Sep;22(9):572-5. doi: 10.1111/exd.12199.

PMID:
23947670
14.

Filaggrin gene mutations and risk of basal cell carcinoma.

Kaae J, Thyssen JP, Johansen JD, Meldgaard M, Linneberg A, Allen M, Skov L.

Br J Dermatol. 2013 Nov;169(5):1162-4. doi: 10.1111/bjd.12573. No abstract available.

PMID:
23927042
15.

Carriers of filaggrin gene (FLG) mutations avoid professional exposure to irritants in adulthood.

Bandier J, Ross-Hansen K, Carlsen BC, Menné T, Linneberg A, Stender S, Szecsi PB, Meldgaard M, Thyssen JP, Johansen JD.

Contact Dermatitis. 2013 Dec;69(6):355-62. doi: 10.1111/cod.12097. Epub 2013 Jun 28.

PMID:
23808934
16.

Filaggrin mutations are strongly associated with contact sensitization in individuals with dermatitis.

Thyssen JP, Linneberg A, Ross-Hansen K, Carlsen BC, Meldgaard M, Szecsi PB, Stender S, Menné T, Johansen JD.

Contact Dermatitis. 2013 May;68(5):273-6. doi: 10.1111/cod.12021. Epub 2013 Jan 24.

PMID:
23343419
17.

Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations.

Thyssen JP, Thuesen B, Huth C, Standl M, Carson CG, Heinrich J, Krämer U, Kratzsch J, Berg ND, Menné T, Johansen JD, Carlsen BC, Schwab S, Thorand B, Munk M, Wallaschofski H, Heickendorff L, Meldgaard M, Szecsi PB, Stender S, Bønnelykke K, Weidinger S, Bisgaard H, Linneberg A.

J Allergy Clin Immunol. 2012 Nov;130(5):1204-1207.e2. doi: 10.1016/j.jaci.2012.06.046. Epub 2012 Aug 24. No abstract available.

PMID:
22921868
18.

Skin prick test reactivity to aeroallergens by filaggrin mutation status.

Hougaard MG, Johansen JD, Linneberg A, Bandier J, Stender S, Carlsen BC, Szecsi PB, Meldgaard M, Menné T, Thyssen JP.

J Eur Acad Dermatol Venereol. 2014 Feb;28(2):238-41. doi: 10.1111/j.1468-3083.2012.04679.x. Epub 2012 Aug 11.

PMID:
22882599
19.

A novel multiplex analysis of filaggrin polymorphisms: a universally applicable method for genotyping.

Meldgaard M, Szecsi PB, Carlsen BC, Thyssen JP, Johansen JD, Menné T, Stender S.

Clin Chim Acta. 2012 Oct 9;413(19-20):1488-92. doi: 10.1016/j.cca.2012.06.014. Epub 2012 Jun 14.

PMID:
22705401
20.

Atopic diseases by filaggrin mutations and birth year.

Thyssen JP, Linneberg A, Johansen JD, Carlsen BC, Zachariae C, Meldgaard M, Szecsi PB, Stender S, Menné T.

Allergy. 2012 May;67(5):705-8. doi: 10.1111/j.1398-9995.2012.02804.x. Epub 2012 Mar 2.

PMID:
22381027
21.

Use of an automated bolus calculator in MDI-treated type 1 diabetes: the BolusCal Study, a randomized controlled pilot study.

Schmidt S, Meldgaard M, Serifovski N, Storm C, Christensen TM, Gade-Rasmussen B, Nørgaard K.

Diabetes Care. 2012 May;35(5):984-90. doi: 10.2337/dc11-2044. Epub 2012 Feb 16.

22.

Interaction between filaggrin null mutations and tobacco smoking in relation to asthma.

Berg ND, Husemoen LL, Thuesen BH, Hersoug LG, Elberling J, Thyssen JP, Carlsen BC, Johansen JD, Menné T, Bønnelykke K, Stender S, Meldgaard M, Szecsi PB, Linneberg A.

J Allergy Clin Immunol. 2012 Feb;129(2):374-80, 380.e1-2. doi: 10.1016/j.jaci.2011.08.045. Epub 2011 Nov 16.

PMID:
22088612
23.

Species-specific responses of Late Quaternary megafauna to climate and humans.

Lorenzen ED, Nogués-Bravo D, Orlando L, Weinstock J, Binladen J, Marske KA, Ugan A, Borregaard MK, Gilbert MT, Nielsen R, Ho SY, Goebel T, Graf KE, Byers D, Stenderup JT, Rasmussen M, Campos PF, Leonard JA, Koepfli KP, Froese D, Zazula G, Stafford TW Jr, Aaris-Sørensen K, Batra P, Haywood AM, Singarayer JS, Valdes PJ, Boeskorov G, Burns JA, Davydov SP, Haile J, Jenkins DL, Kosintsev P, Kuznetsova T, Lai X, Martin LD, McDonald HG, Mol D, Meldgaard M, Munch K, Stephan E, Sablin M, Sommer RS, Sipko T, Scott E, Suchard MA, Tikhonov A, Willerslev R, Wayne RK, Cooper A, Hofreiter M, Sher A, Shapiro B, Rahbek C, Willerslev E.

Nature. 2011 Nov 2;479(7373):359-64. doi: 10.1038/nature10574.

24.

A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study.

Thyssen JP, Linneberg A, Carlsen BC, Johansen JD, Engkilde K, Hansen T, Pociot F, Pedersen O, Meldgaard M, Szecsi PB, Stender S, Menné T.

BMJ Open. 2011 Mar 15;1(1):e000062. doi: 10.1136/bmjopen-2011-000062.

25.

Filaggrin loss-of-function mutation R501X and 2282del4 carrier status is associated with fissured skin on the hands: results from a cross-sectional population study.

Thyssen JP, Ross-Hansen K, Johansen JD, Zachariae C, Carlsen BC, Linneberg A, Bisgaard H, Carson CG, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Menné T.

Br J Dermatol. 2012 Jan;166(1):46-53. doi: 10.1111/j.1365-2133.2011.10530.x. Epub 2011 Nov 2.

PMID:
21777221
26.

The filaggrin null genotypes R501X and 2282del4 seem not to be associated with psoriasis: results from general population study and meta-analysis.

Thyssen JP, Johansen JD, Carlsen BC, Linneberg A, Meldgaard M, Szecsi PB, Stender S, Menné T.

J Eur Acad Dermatol Venereol. 2012 Jun;26(6):782-4. doi: 10.1111/j.1468-3083.2011.04107.x. Epub 2011 May 13.

PMID:
21564328
27.

Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible.

Thyssen JP, Carlsen BC, Bisgaard H, Giwercman C, Johansen JD, Linneberg A, Meldgaard M, Szecsi PB, Stender S, Menné T.

J Eur Acad Dermatol Venereol. 2012 Mar;26(3):386-9. doi: 10.1111/j.1468-3083.2011.04073.x. Epub 2011 Apr 19.

PMID:
21501248
28.

Association between filaggrin null mutations and concomitant atopic dermatitis and contact allergy.

Carlsen BC, Thyssen JP, Menné T, Meldgaard M, Linneberg A, Nielsen NH, Szecsi PB, Stender S, Johansen JD.

Clin Exp Dermatol. 2011 Jul;36(5):467-72. doi: 10.1111/j.1365-2230.2010.03994.x. Epub 2011 Mar 11.

PMID:
21434976
29.

Nickel reactivity and filaggrin null mutations--evaluation of the filaggrin bypass theory in a general population.

Ross-Hansen K, Menné T, Johansen JD, Carlsen BC, Linneberg A, Nielsen NH, Stender S, Meldgaard M, Szecsi PB, Thyssen JP.

Contact Dermatitis. 2011 Jan;64(1):24-31. doi: 10.1111/j.1600-0536.2010.01815.x.

PMID:
21166815
30.

Latex allergy and filaggrin null mutations.

Carlsen BC, Meldgaard M, Hamann D, Hamann Q, Hamann C, Thyssen JP, Meyer DM, Gruninger SE, Hamann C.

J Dent. 2011 Feb;39(2):128-32. doi: 10.1016/j.jdent.2010.11.001. Epub 2010 Nov 11.

PMID:
21074596
31.

Filaggrin null-mutations may be associated with a distinct subtype of atopic hand eczema.

Thyssen JP, Carlsen BC, Johansen JD, Meldgaard M, Szecsi PB, Stender S, Menné T.

Acta Derm Venereol. 2010 Sep;90(5):528. doi: 10.2340/00015555-0883. No abstract available.

32.

Filaggrin null mutations and association with contact allergy and allergic contact dermatitis: results from a tertiary dermatology clinic.

Carlsen BC, Johansen JD, Menné T, Meldgaard M, Szecsi PB, Stender S, Thyssen JP.

Contact Dermatitis. 2010 Aug;63(2):89-95. doi: 10.1111/j.1600-0536.2010.01748.x.

PMID:
20629673
33.

Filaggrin haploinsufficiency among patients with dermatitis from a tertiary referral centre: early findings and possible phenotype.

Thyssen JP, Carlsen BC, Johansen JD, Meldgaard M, Szecsi PB, Stender S, Menné T.

Contact Dermatitis. 2010 Mar;62(3):182-3. doi: 10.1111/j.1600-0536.2009.01687.x. No abstract available.

PMID:
20565506
34.

Filaggrin null mutations increase the risk and persistence of hand eczema in subjects with atopic dermatitis: results from a general population study.

Thyssen JP, Carlsen BC, Menné T, Linneberg A, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Johansen JD.

Br J Dermatol. 2010 Jul;163(1):115-20. doi: 10.1111/j.1365-2133.2010.09822.x. Epub 2010 Apr 23.

PMID:
20426775
35.

The association between null mutations in the filaggrin gene and contact sensitization to nickel and other chemicals in the general population.

Thyssen JP, Johansen JD, Linneberg A, Menné T, Nielsen NH, Meldgaard M, Szecsi PB, Stender S, Carlsen BC.

Br J Dermatol. 2010 Jun;162(6):1278-85. doi: 10.1111/j.1365-2133.2010.09708.x. Epub 2010 Mar 25.

PMID:
20346018
36.

Ancient human genome sequence of an extinct Palaeo-Eskimo.

Rasmussen M, Li Y, Lindgreen S, Pedersen JS, Albrechtsen A, Moltke I, Metspalu M, Metspalu E, Kivisild T, Gupta R, Bertalan M, Nielsen K, Gilbert MT, Wang Y, Raghavan M, Campos PF, Kamp HM, Wilson AS, Gledhill A, Tridico S, Bunce M, Lorenzen ED, Binladen J, Guo X, Zhao J, Zhang X, Zhang H, Li Z, Chen M, Orlando L, Kristiansen K, Bak M, Tommerup N, Bendixen C, Pierre TL, Grønnow B, Meldgaard M, Andreasen C, Fedorova SA, Osipova LP, Higham TF, Ramsey CB, Hansen TV, Nielsen FC, Crawford MH, Brunak S, Sicheritz-Pontén T, Villems R, Nielsen R, Krogh A, Wang J, Willerslev E.

Nature. 2010 Feb 11;463(7282):757-62. doi: 10.1038/nature08835.

37.

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

Lambertsen KL, Clausen BH, Babcock AA, Gregersen R, Fenger C, Nielsen HH, Haugaard LS, Wirenfeldt M, Nielsen M, Dagnaes-Hansen F, Bluethmann H, Faergeman NJ, Meldgaard M, Deierborg T, Finsen B.

J Neurosci. 2009 Feb 4;29(5):1319-30. doi: 10.1523/JNEUROSCI.5505-08.2009.

38.

Nuclear translocation of endonuclease G in degenerating neurons after permanent middle cerebral artery occlusion in mice.

Nielsen M, Lambertsen KL, Clausen BH, Meldgaard M, Diemer NH, Zimmer J, Finsen B.

Exp Brain Res. 2009 Mar;194(1):17-27. doi: 10.1007/s00221-008-1665-5. Epub 2009 Jan 13.

PMID:
19139873
39.

Modified and reliable procedure for non-invasive sampling and extraction of mouse DNA.

Meldgaard M.

Lab Anim. 2008 Oct;42(4):515. doi: 10.1258/la.2007.007141. Epub 2008 Sep 9. No abstract available.

PMID:
18782828
40.

Paleo-Eskimo mtDNA genome reveals matrilineal discontinuity in Greenland.

Gilbert MT, Kivisild T, Grønnow B, Andersen PK, Metspalu E, Reidla M, Tamm E, Axelsson E, Götherström A, Campos PF, Rasmussen M, Metspalu M, Higham TF, Schwenninger JL, Nathan R, De Hoog CJ, Koch A, Møller LN, Andreasen C, Meldgaard M, Villems R, Bendixen C, Willerslev E.

Science. 2008 Jun 27;320(5884):1787-9. doi: 10.1126/science.1159750. Epub 2008 May 29.

41.

The function of the human interferon-beta 1a glycan determined in vivo.

Dissing-Olesen L, Thaysen-Andersen M, Meldgaard M, Højrup P, Finsen B.

J Pharmacol Exp Ther. 2008 Jul;326(1):338-47. doi: 10.1124/jpet.108.138263. Epub 2008 Apr 29.

42.

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice.

Degn M, Lambertsen KL, Petersen G, Meldgaard M, Artmann A, Clausen BH, Hansen SH, Finsen B, Hansen HS, Lund TM.

J Neurochem. 2007 Dec;103(5):1907-16. Epub 2007 Sep 14.

43.

Population control of resident and immigrant microglia by mitosis and apoptosis.

Wirenfeldt M, Dissing-Olesen L, Anne Babcock A, Nielsen M, Meldgaard M, Zimmer J, Azcoitia I, Leslie RG, Dagnaes-Hansen F, Finsen B.

Am J Pathol. 2007 Aug;171(2):617-31. Epub 2007 Jun 28.

44.

Microglia and macrophages express tumor necrosis factor receptor p75 following middle cerebral artery occlusion in mice.

Lambertsen KL, Clausen BH, Fenger C, Wulf H, Owens T, Dagnaes-Hansen F, Meldgaard M, Finsen B.

Neuroscience. 2007 Feb 9;144(3):934-49. Epub 2006 Dec 11.

PMID:
17161916
45.

Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain.

Pedersen MD, Minuzzi L, Wirenfeldt M, Meldgaard M, Slidsborg C, Cumming P, Finsen B.

Eur J Neurosci. 2006 Aug;24(4):991-1000.

PMID:
16930426
46.

Tumor necrosis factor and its p55 and p75 receptors are not required for axonal lesion-induced microgliosis in mouse fascia dentata.

Fenger C, Drojdahl N, Wirenfeldt M, Sylvest L, Jorgensen OS, Meldgaard M, Lambertsen KL, Finsen B.

Glia. 2006 Nov 1;54(6):591-605.

PMID:
16927297
47.

Validation of two reference genes for mRNA level studies of murine disease models in neurobiology.

Meldgaard M, Fenger C, Lambertsen KL, Pedersen MD, Ladeby R, Finsen B.

J Neurosci Methods. 2006 Sep 30;156(1-2):101-10. Epub 2006 Mar 22.

PMID:
16554095
49.

A quantitative study of microglial-macrophage synthesis of tumor necrosis factor during acute and late focal cerebral ischemia in mice.

Lambertsen KL, Meldgaard M, Ladeby R, Finsen B.

J Cereb Blood Flow Metab. 2005 Jan;25(1):119-35.

PMID:
15678118
50.

Non-invasive method for sampling and extraction of mouse DNA for PCR.

Meldgaard M, Bollen PJ, Finsen B.

Lab Anim. 2004 Oct;38(4):413-7.

PMID:
15479556

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