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Items: 1 to 50 of 351

1.

Facilitators of adaptation and antifungal resistance mechanisms in clinically relevant fungi.

Hokken MWJ, Zwaan BJ, Melchers WJG, Verweij PE.

Fungal Genet Biol. 2019 Jul 18:103254. doi: 10.1016/j.fgb.2019.103254. [Epub ahead of print] Review.

PMID:
31326470
2.

Environmental Hotspots for Azole Resistance Selection of Aspergillus fumigatus, the Netherlands.

Schoustra SE, Debets AJM, Rijs AJMM, Zhang J, Snelders E, Leendertse PC, Melchers WJG, Rietveld AG, Zwaan BJ, Verweij PE.

Emerg Infect Dis. 2019 Jul;25(7):1347-1353. doi: 10.3201/eid2507.181625.

3.

Raw genome sequence data for 13 isogenic Aspergillus fumigatus strains isolated over a 2 year period from a patient with chronic granulomatous disease.

Ballard E, Zoll J, Melchers WJG, Brown AJP, Warris A, Verweij PE.

Data Brief. 2019 May 23;25:104021. doi: 10.1016/j.dib.2019.104021. eCollection 2019 Aug.

4.

Recreation of in-host acquired single nucleotide polymorphisms by CRISPR-Cas9 reveals an uncharacterised gene playing a role in Aspergillus fumigatus azole resistance via a non-cyp51A mediated resistance mechanism.

Ballard E, Weber J, Melchers WJG, Tammireddy S, Whitfield PD, Brakhage AA, Brown AJP, Verweij PE, Warris A.

Fungal Genet Biol. 2019 May 23;130:98-106. doi: 10.1016/j.fgb.2019.05.005. [Epub ahead of print]

5.

Relevance of heterokaryosis for adaptation and azole-resistance development in Aspergillus fumigatus.

Zhang J, Snelders EE, Zwaan BJ, Schoustra SE, Kuijper EJ, Arendrup MC, Melchers WJG, Verweij PE, Debets AJM.

Proc Biol Sci. 2019 Feb 13;286(1896):20182886. doi: 10.1098/rspb.2018.2886.

PMID:
30963936
6.

Impact of molecular point-of-care testing on clinical management and in-hospital costs of patients suspected of influenza or RSV infection: a modeling study.

Rahamat-Langendoen J, Groenewoud H, Kuijpers J, Melchers WJG, van der Wilt GJ.

J Med Virol. 2019 Aug;91(8):1408-1414. doi: 10.1002/jmv.25479. Epub 2019 Apr 14.

PMID:
30950066
7.

Aerosol Transmission of Aspergillus fumigatus in Cystic Fibrosis Patients in the Netherlands.

Engel TGP, Erren E, Vanden Driessche KSJ, Melchers WJG, Reijers MH, Merkus P, Verweij PE.

Emerg Infect Dis. 2019 Apr;25(4):797-799. doi: 10.3201/eid2504.181110.

8.

Post-Colposcopy Management and Progression Predictors of Biopsy-Proven CIN1 in Women Under 25 Years.

Loopik DL, Bekkers RLM, Massuger LFAG, Melchers WJG, Siebers AG, Bentley JR.

J Obstet Gynaecol Can. 2019 Mar;41(3):292-299. doi: 10.1016/j.jogc.2018.06.021. Epub 2018 Oct 27.

PMID:
30786980
9.

Risk Factors and Clinical Outcomes of Head and Neck Cancer in Inflammatory Bowel Disease: A Nationwide Cohort Study.

Nissen LHC, Derikx LAAP, Jacobs AME, van Herpen CM, Kievit W, Verhoeven R, van den Broek E, Bekers E, van den Heuvel T, Pierik M, Rahamat-Langendoen J, Takes RP, Melchers WJG, Nagtegaal ID, Hoentjen F; Dutch Initiative on Crohn and Colitis (ICC); Dutch Head and Neck Society, PALGA group; IBD/HNC group.

Inflamm Bowel Dis. 2018 Aug 16;24(9):2015-2026. doi: 10.1093/ibd/izy096.

PMID:
30759216
10.

Performance of human papillomavirus testing on self-collected versus clinician-collected samples for the detection of cervical intraepithelial neoplasia of grade 2 or worse: a randomised, paired screen-positive, non-inferiority trial.

Polman NJ, Ebisch RMF, Heideman DAM, Melchers WJG, Bekkers RLM, Molijn AC, Meijer CJLM, Quint WGV, Snijders PJF, Massuger LFAG, van Kemenade FJ, Berkhof J.

Lancet Oncol. 2019 Feb;20(2):229-238. doi: 10.1016/S1470-2045(18)30763-0. Epub 2019 Jan 15.

PMID:
30658933
11.

Phenotypic plasticity and the evolution of azole resistance in Aspergillus fumigatus; an expression profile of clinical isolates upon exposure to itraconazole.

Hokken MWJ, Zoll J, Coolen JPM, Zwaan BJ, Verweij PE, Melchers WJG.

BMC Genomics. 2019 Jan 9;20(1):28. doi: 10.1186/s12864-018-5255-z.

12.

Triazole resistance in Aspergillus fumigatus: recent insights and challenges for patient management.

Lestrade PPA, Meis JF, Melchers WJG, Verweij PE.

Clin Microbiol Infect. 2019 Jul;25(7):799-806. doi: 10.1016/j.cmi.2018.11.027. Epub 2018 Dec 21. Review.

PMID:
30580035
13.

Trends in Azole Resistance in Aspergillus fumigatus, the Netherlands, 1994-2016.

Buil JB, Snelders E, Denardi LB, Melchers WJG, Verweij PE.

Emerg Infect Dis. 2019 Jan;25(1):176-178. doi: 10.3201/eid2501.171925.

14.

Prevalence and diversity of filamentous fungi in the airways of cystic fibrosis patients - A Dutch, multicentre study.

Engel TGP, Slabbers L, de Jong C, Melchers WJG, Hagen F, Verweij PE, Merkus P, Meis JF; Dutch Cystic Fibrosis Fungal Collection Consortium.

J Cyst Fibros. 2019 Mar;18(2):221-226. doi: 10.1016/j.jcf.2018.11.012. Epub 2018 Dec 1.

PMID:
30514613
15.

Justifying conservative management of CIN2 in women younger than 25 years - A population-based study.

Loopik DL, Bekkers RLM, Massuger LFAG, Melchers WJG, Siebers AG, Bentley J.

Gynecol Oncol. 2019 Jan;152(1):82-86. doi: 10.1016/j.ygyno.2018.10.038. Epub 2018 Nov 7.

PMID:
30413339
16.

Screening for persistent high-risk HPV infections may be a valuable screening method for young women; A retrospective cohort study.

Ebisch RMF, Ketelaars PJW, van der Sanden WMH, Schmeink CE, Lenselink CH, Siebers AG, Massuger LFAG, Melchers WJG, Bekkers RLM.

PLoS One. 2018 Oct 24;13(10):e0206219. doi: 10.1371/journal.pone.0206219. eCollection 2018.

17.

Voriconazole Resistance and Mortality in Invasive Aspergillosis: A Multicenter Retrospective Cohort Study.

Lestrade PP, Bentvelsen RG, Schauwvlieghe AFAD, Schalekamp S, van der Velden WJFM, Kuiper EJ, van Paassen J, van der Hoven B, van der Lee HA, Melchers WJG, de Haan AF, van der Hoeven HL, Rijnders BJA, van der Beek MT, Verweij PE.

Clin Infect Dis. 2019 Apr 24;68(9):1463-1471. doi: 10.1093/cid/ciy859.

PMID:
30307492
18.

Defining hrHPV genotypes in cervical intraepithelial neoplasia by laser capture microdissection supports reflex triage of self-samples using HPV16/18 and FAM19A4/miR124-2 methylation.

Leeman A, Ebisch RMF, Kasius A, Bosgraaf RP, Jenkins D, van de Sandt MM, de Strooper LMA, Heideman DAM, Snijders PJF, Massuger LFAG, Bekkers RLM, Meijer CJLM, van Kemenade FJ, Quint WGV, Melchers WJG.

Gynecol Oncol. 2018 Nov;151(2):311-318. doi: 10.1016/j.ygyno.2018.09.006. Epub 2018 Sep 13.

PMID:
30219239
19.

Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer.

Snoek BC, Verlaat W, Babion I, Novianti PW, van de Wiel MA, Wilting SM, van Trommel NE, Bleeker MCG, Massuger LFAG, Melchers WJG, Sie D, Heideman DAM, Snijders PJF, Meijer CJLM, Steenbergen RDM.

Int J Cancer. 2019 Jan 15;144(2):372-379. doi: 10.1002/ijc.31855. Epub 2018 Nov 4.

20.

Discovery and characterization of novel Aspergillus fumigatus mycoviruses.

Zoll J, Verweij PE, Melchers WJG.

PLoS One. 2018 Jul 25;13(7):e0200511. doi: 10.1371/journal.pone.0200511. eCollection 2018.

21.

Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.

Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A Jr, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL.

Nat Commun. 2018 Jul 6;9(1):2636. doi: 10.1038/s41467-018-04912-3.

22.

Gene co-expression analysis identifies gene clusters associated with isotropic and polarized growth in Aspergillus fumigatus conidia.

Baltussen TJH, Coolen JPM, Zoll J, Verweij PE, Melchers WJG.

Fungal Genet Biol. 2018 Jul;116:62-72. doi: 10.1016/j.fgb.2018.04.013. Epub 2018 Apr 26.

23.

Development and first evaluation of a novel multiplex real-time PCR on whole blood samples for rapid pathogen identification in critically ill patients with sepsis.

van de Groep K, Bos MP, Savelkoul PHM, Rubenjan A, Gazenbeek C, Melchers WJG, van der Poll T, Juffermans NP, Ong DSY, Bonten MJM, Cremer OL; MARS consortium.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1333-1344. doi: 10.1007/s10096-018-3255-1. Epub 2018 Apr 26.

24.

Identification and Validation of a 3-Gene Methylation Classifier for HPV-Based Cervical Screening on Self-Samples.

Verlaat W, Snoek BC, Heideman DAM, Wilting SM, Snijders PJF, Novianti PW, van Splunter AP, Peeters CFW, van Trommel NE, Massuger LFAG, Bekkers RLM, Melchers WJG, van Kemenade FJ, Berkhof J, van de Wiel MA, Meijer CJLM, Steenbergen RDM.

Clin Cancer Res. 2018 Jul 15;24(14):3456-3464. doi: 10.1158/1078-0432.CCR-17-3615. Epub 2018 Apr 9.

25.

Molecular Detection of Azole-Resistant Aspergillus fumigatus in Clinical Samples.

Buil JB, Zoll J, Verweij PE, Melchers WJG.

Front Microbiol. 2018 Mar 21;9:515. doi: 10.3389/fmicb.2018.00515. eCollection 2018. Review.

26.

Vulvar cancer: Two pathways with different localization and prognosis.

Hinten F, Molijn A, Eckhardt L, Massuger LFAG, Quint W, Bult P, Bulten J, Melchers WJG, de Hullu JA.

Gynecol Oncol. 2018 May;149(2):310-317. doi: 10.1016/j.ygyno.2018.03.003. Epub 2018 Mar 16.

PMID:
29555332
27.

In-host microevolution of Aspergillus fumigatus: A phenotypic and genotypic analysis.

Ballard E, Melchers WJG, Zoll J, Brown AJP, Verweij PE, Warris A.

Fungal Genet Biol. 2018 Apr;113:1-13. doi: 10.1016/j.fgb.2018.02.003. Epub 2018 Feb 23.

28.

Epidemiology of invasive aspergillosis and triazole-resistant Aspergillus fumigatus in patients with haematological malignancies: a single-centre retrospective cohort study.

Lestrade PP, van der Velden WJFM, Bouwman F, Stoop FJ, Blijlevens NMA, Melchers WJG, Verweij PE, Donnelly JP.

J Antimicrob Chemother. 2018 May 1;73(5):1389-1394. doi: 10.1093/jac/dkx527.

PMID:
29394399
29.

The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression.

Gresnigt MS, Jaeger M, Subbarao Malireddi RK, Rasid O, Jouvion G, Fitting C, Melchers WJG, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL.

Front Immunol. 2017 Dec 13;8:1777. doi: 10.3389/fimmu.2017.01777. eCollection 2017.

30.

Isavuconazole susceptibility of clinical Aspergillus fumigatus isolates and feasibility of isavuconazole dose escalation to treat isolates with elevated MICs.

Buil JB, Brüggemann RJM, Wasmann RE, Zoll J, Meis JF, Melchers WJG, Mouton JW, Verweij PE.

J Antimicrob Chemother. 2018 Jan 1;73(1):263. doi: 10.1093/jac/dkx425. No abstract available.

PMID:
29112717
31.

Correction for Quainoo et al., "Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis".

Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL.

Clin Microbiol Rev. 2017 Nov 1;31(1). pii: e00082-17. doi: 10.1128/CMR.00082-17. Print 2018 Jan. No abstract available.

32.

Isavuconazole susceptibility of clinical Aspergillus fumigatus isolates and feasibility of isavuconazole dose escalation to treat isolates with elevated MICs.

Buil JB, Brüggemann RJM, Wasmann RE, Zoll J, Meis JF, Melchers WJG, Mouton JW, Verweij PE.

J Antimicrob Chemother. 2018 Jan 1;73(1):134-142. doi: 10.1093/jac/dkx354. Erratum in: J Antimicrob Chemother. 2018 Jan 1;73(1):263.

PMID:
29048485
33.

Evolution of cross-resistance to medical triazoles in Aspergillus fumigatus through selection pressure of environmental fungicides.

Zhang J, van den Heuvel J, Debets AJM, Verweij PE, Melchers WJG, Zwaan BJ, Schoustra SE.

Proc Biol Sci. 2017 Sep 27;284(1863). pii: 20170635. doi: 10.1098/rspb.2017.0635.

34.

Single-Center Evaluation of an Agar-Based Screening for Azole Resistance in Aspergillus fumigatus by Using VIPcheck.

Buil JB, van der Lee HAL, Rijs AJMM, Zoll J, Hovestadt JAMF, Melchers WJG, Verweij PE.

Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01250-17. doi: 10.1128/AAC.01250-17. Print 2017 Dec.

35.

Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis.

Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL.

Clin Microbiol Rev. 2017 Oct;30(4):1015-1063. doi: 10.1128/CMR.00016-17. Review. Erratum in: Clin Microbiol Rev. 2017 Nov 1;31(1):.

36.

The effect of video information on anxiety levels in women attending colposcopy: a randomized controlled trial.

Ketelaars PJW, Buskes MHM, Bosgraaf RP, van Hamont D, Prins JB, Massuger LFAG, Melchers WJG, Bekkers RLM.

Acta Oncol. 2017 Dec;56(12):1728-1733. doi: 10.1080/0284186X.2017.1355108. Epub 2017 Aug 1.

PMID:
28760058
37.

Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study.

Alanio A, Gits-Muselli M, Guigue N, Desnos-Ollivier M, Calderon EJ, Di Cave D, Dupont D, Hamprecht A, Hauser PM, Helweg-Larsen J, Kicia M, Lagrou K, Lengerova M, Matos O, Melchers WJG, Morio F, Nevez G, Totet A, White LP, Bretagne S.

EBioMedicine. 2017 Aug;22:155-163. doi: 10.1016/j.ebiom.2017.06.027. Epub 2017 Jun 29.

38.

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence.

Zhang J, Snelders E, Zwaan BJ, Schoustra SE, Meis JF, van Dijk K, Hagen F, van der Beek MT, Kampinga GA, Zoll J, Melchers WJG, Verweij PE, Debets AJM.

MBio. 2017 Jun 27;8(3). pii: e00791-17. doi: 10.1128/mBio.00791-17.

39.

In vitro activity of the novel antifungal compound F901318 against difficult-to-treat Aspergillus isolates.

Buil JB, Rijs AJMM, Meis JF, Birch M, Law D, Melchers WJG, Verweij PE.

J Antimicrob Chemother. 2017 Sep 1;72(9):2548-2552. doi: 10.1093/jac/dkx177.

PMID:
28605488
40.

High-risk human papillomavirus detection in self-sampling compared to physician-taken smear in a responder population of the Dutch cervical screening: Results of the VERA study.

Ketelaars PJW, Bosgraaf RP, Siebers AG, Massuger LFAG, van der Linden JC, Wauters CAP, Rahamat-Langendoen JC, van den Brule AJC, IntHout J, Melchers WJG, Bekkers RLM.

Prev Med. 2017 Aug;101:96-101. doi: 10.1016/j.ypmed.2017.05.021. Epub 2017 Jun 1.

41.

Long-Lasting Increased Risk of Human Papillomavirus-Related Carcinomas and Premalignancies After Cervical Intraepithelial Neoplasia Grade 3: A Population-Based Cohort Study.

Ebisch RMF, Rutten DWE, IntHout J, Melchers WJG, Massuger LFAG, Bulten J, Bekkers RLM, Siebers AG.

J Clin Oncol. 2017 Aug 1;35(22):2542-2550. doi: 10.1200/JCO.2016.71.4543. Epub 2017 May 25.

PMID:
28541790
42.

In Vivo Efficacy of Liposomal Amphotericin B against Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates in Two Different Immunosuppression Models of Invasive Aspergillosis.

Seyedmousavi S, Mouton JW, Melchers WJG, Verweij PE.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e02479-16. doi: 10.1128/AAC.02479-16. Print 2017 Jun.

43.

Successful treatment of azole-resistant invasive aspergillosis in a bottlenose dolphin with high-dose posaconazole.

Bunskoek PE, Seyedmousavi S, Gans SJ, van Vierzen PB, Melchers WJ, van Elk CE, Mouton JW, Verweij PE.

Med Mycol Case Rep. 2017 Apr 1;16:16-19. doi: 10.1016/j.mmcr.2017.03.005. eCollection 2017 Jun.

44.

Multimodal Hyperspectroscopic Imaging for Detection of High-Grade Cervical Intraepithelial Neoplasia.

Ebisch RMF, Hermens M, van den Akker PAJ, Massuger LFAG, Melchers WJG, Bekkers RLM.

J Low Genit Tract Dis. 2017 Jul;21(3):166-170. doi: 10.1097/LGT.0000000000000309.

PMID:
28403024
45.

Evaluation of p16/Ki-67 dual-stained cytology as triage test for high-risk human papillomavirus-positive women.

Ebisch RM, van der Horst J, Hermsen M, Rijstenberg LL, Vedder JE, Bulten J, Bosgraaf RP, Verhoef VM, Heideman DA, Snijders PJ, Meijer CJ, van Kemenade FJ, Massuger LF, Melchers WJ, Bekkers RL, Siebers AG.

Mod Pathol. 2017 Jul;30(7):1021-1031. doi: 10.1038/modpathol.2017.16. Epub 2017 Mar 17.

46.

Genetic Diversity and In Vitro Antifungal Susceptibility of 200 Clinical and Environmental Aspergillus flavus Isolates.

Taghizadeh-Armaki M, Hedayati MT, Ansari S, Omran SM, Saber S, Rafati H, Zoll J, van der Lee HA, Melchers WJG, Verweij PE, Seyedmousavi S.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e00004-17. doi: 10.1128/AAC.00004-17. Print 2017 May.

47.

Lab-in-a-tube: Real-time molecular point-of-care diagnostics for influenza A and B using the cobas® Liat® system.

Melchers WJG, Kuijpers J, Sickler JJ, Rahamat-Langendoen J.

J Med Virol. 2017 Aug;89(8):1382-1386. doi: 10.1002/jmv.24796. Epub 2017 Mar 14.

PMID:
28213975
48.

Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients-authors' response.

Cordonnier C, Alanio A, Cesaro S, Maschmeyer G, Einsele H, Donnelly JP, Hauser PM, Lagrou K, Melchers WJ, Helweg-Larsen J, Matos O, Bretagne S, Maertens J; Fifth European Conference on Infections in Leukemia (ECIL-5; a joint venture of The European Group for Blood and Marrow Transplantation (EBMT), The European Organization for Research and Treatment of Cancer (EORTC), the Immunocompromised Host Society (ICHS) and The European LeukemiaNet (ELN).

J Antimicrob Chemother. 2017 Apr 1;72(4):1266-1268. doi: 10.1093/jac/dkw580. No abstract available.

PMID:
28122911
49.

Reactivation of Latent HPV Infections After Renal Transplantation.

Hinten F, Hilbrands LB, Meeuwis KAP, IntHout J, Quint WGV, Hoitsma AJ, Massuger LFAG, Melchers WJG, de Hullu JA.

Am J Transplant. 2017 Jun;17(6):1563-1573. doi: 10.1111/ajt.14181. Epub 2017 Feb 2.

50.

Using a semi-conductor sequencing-based panel for genotyping of HPV-positive and HPV-negative oropharyngeal cancer: a retrospective pilot study.

Ham JC, Tops BBJ, Driessen CML, van Raaij AWM, Slootweg PJ, Melchers WJG, Ligtenberg MJL, van Herpen CML.

Clin Otolaryngol. 2017 Jun;42(3):681-686. doi: 10.1111/coa.12800. Epub 2017 Jan 8.

PMID:
27882657

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