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Items: 1 to 50 of 293

1.

Stable lines and clones of long-term proliferating normal, genetically unmodified murine common lymphoid progenitors.

Kawano Y, Petkau G, Stehle C, Durek P, Heinz GA, Tanimoto K, Karasuyama H, Mashreghi MF, Romagnani C, Melchers F.

Blood. 2018 May 3;131(18):2026-2035. doi: 10.1182/blood-2017-09-805259. Epub 2018 Mar 23.

PMID:
29572379
2.

MiR221 promotes precursor B-cell retention in the bone marrow by amplifying the PI3K-signaling pathway in mice.

Petkau G, Kawano Y, Wolf I, Knoll M, Melchers F.

Eur J Immunol. 2018 Jun;48(6):975-989. doi: 10.1002/eji.201747354. Epub 2018 Mar 15.

PMID:
29505092
3.

Mycobacterium tuberculosis-Infected Hematopoietic Stem and Progenitor Cells Unable to Express Inducible Nitric Oxide Synthase Propagate Tuberculosis in Mice.

Reece ST, Vogelzang A, Tornack J, Bauer W, Zedler U, Schommer-Leitner S, Stingl G, Melchers F, Kaufmann SHE.

J Infect Dis. 2018 Apr 23;217(10):1667-1671. doi: 10.1093/infdis/jiy041.

4.

Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature.

Reismann D, Stefanowski J, Günther R, Rakhymzhan A, Matthys R, Nützi R, Zehentmeier S, Schmidt-Bleek K, Petkau G, Chang HD, Naundorf S, Winter Y, Melchers F, Duda G, Hauser AE, Niesner RA.

Nat Commun. 2017 Dec 18;8(1):2153. doi: 10.1038/s41467-017-01538-9.

5.

Selective targeting of pro-inflammatory Th1 cells by microRNA-148a-specific antagomirs in vivo.

Maschmeyer P, Petkau G, Siracusa F, Zimmermann J, Zügel F, Kühl AA, Lehmann K, Schimmelpfennig S, Weber M, Haftmann C, Riedel R, Bardua M, Heinz GA, Tran CL, Hoyer BF, Hiepe F, Herzog S, Wittmann J, Rajewsky N, Melchers FG, Chang HD, Radbruch A, Mashreghi MF.

J Autoimmun. 2018 May;89:41-52. doi: 10.1016/j.jaut.2017.11.005. Epub 2017 Dec 1.

6.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Cossarizza A, Chang HD, Radbruch A, Akdis M, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, Boulais PE, Brinkman RR, Büscher M, Busch DH, Bushnell TP, Cao X, Cavani A, Chattopadhyay PK, Cheng Q, Chow S, Clerici M, Cooke A, Cosma A, Cosmi L, Cumano A, Dang VD, Davies D, De Biasi S, Del Zotto G, Della Bella S, Dellabona P, Deniz G, Dessing M, Diefenbach A, Di Santo J, Dieli F, Dolf A, Donnenberg VS, Dörner T, Ehrhardt GRA, Endl E, Engel P, Engelhardt B, Esser C, Everts B, Dreher A, Falk CS, Fehniger TA, Filby A, Fillatreau S, Follo M, Förster I, Foster J, Foulds GA, Frenette PS, Galbraith D, Garbi N, García-Godoy MD, Geginat J, Ghoreschi K, Gibellini L, Goettlinger C, Goodyear CS, Gori A, Grogan J, Gross M, Grützkau A, Grummitt D, Hahn J, Hammer Q, Hauser AE, Haviland DL, Hedley D, Herrera G, Herrmann M, Hiepe F, Holland T, Hombrink P, Houston JP, Hoyer BF, Huang B, Hunter CA, Iannone A, Jäck HM, Jávega B, Jonjic S, Juelke K, Jung S, Kaiser T, Kalina T, Keller B, Khan S, Kienhöfer D, Kroneis T, Kunkel D, Kurts C, Kvistborg P, Lannigan J, Lantz O, Larbi A, LeibundGut-Landmann S, Leipold MD, Levings MK, Litwin V, Liu Y, Lohoff M, Lombardi G, Lopez L, Lovett-Racke A, Lubberts E, Ludewig B, Lugli E, Maecker HT, Martrus G, Matarese G, Maueröder C, McGrath M, McInnes I, Mei HE, Melchers F, Melzer S, Mielenz D, Mills K, Mirrer D, Mjösberg J, Moore J, Moran B, Moretta A, Moretta L, Mosmann TR, Müller S, Müller W, Münz C, Multhoff G, Munoz LE, Murphy KM, Nakayama T, Nasi M, Neudörfl C, Nolan J, Nourshargh S, O'Connor JE, Ouyang W, Oxenius A, Palankar R, Panse I, Peterson P, Peth C, Petriz J, Philips D, Pickl W, Piconese S, Pinti M, Pockley AG, Podolska MJ, Pucillo C, Quataert SA, Radstake TRDJ, Rajwa B, Rebhahn JA, Recktenwald D, Remmerswaal EBM, Rezvani K, Rico LG, Robinson JP, Romagnani C, Rubartelli A, Ruckert B, Ruland J, Sakaguchi S, Sala-de-Oyanguren F, Samstag Y, Sanderson S, Sawitzki B, Scheffold A, Schiemann M, Schildberg F, Schimisky E, Schmid SA, Schmitt S, Schober K, Schüler T, Schulz AR, Schumacher T, Scotta C, Shankey TV, Shemer A, Simon AK, Spidlen J, Stall AM, Stark R, Stehle C, Stein M, Steinmetz T, Stockinger H, Takahama Y, Tarnok A, Tian Z, Toldi G, Tornack J, Traggiai E, Trotter J, Ulrich H, van der Braber M, van Lier RAW, Veldhoen M, Vento-Asturias S, Vieira P, Voehringer D, Volk HD, von Volkmann K, Waisman A, Walker R, Ward MD, Warnatz K, Warth S, Watson JV, Watzl C, Wegener L, Wiedemann A, Wienands J, Willimsky G, Wing J, Wurst P, Yu L, Yue A, Zhang Q, Zhao Y, Ziegler S, Zimmermann J.

Eur J Immunol. 2017 Oct;47(10):1584-1797. doi: 10.1002/eji.201646632. No abstract available.

PMID:
29023707
7.

The unmet need in rheumatology: Reports from the targeted therapies meeting 2017.

Winthrop KL, Strand V, van der Heijde D, Mease P, Crow M, Weinblatt M, Bathon J, Burmester GR, Dougados M, Kay J, Mariette X, Van Vollenhoven R, Sieper J, Melchers F, Breedfeld FC, Kalden J, Smolen JS, Furst DE.

Clin Immunol. 2018 Jan;186:87-93. doi: 10.1016/j.clim.2017.08.009. Epub 2017 Aug 12.

PMID:
28811201
8.

Flt3 ligand-eGFP-reporter expression characterizes functionally distinct subpopulations of CD150+ long-term repopulating murine hematopoietic stem cells.

Tornack J, Kawano Y, Garbi N, Hämmerling GJ, Melchers F, Tsuneto M.

Eur J Immunol. 2017 Sep;47(9):1477-1487. doi: 10.1002/eji.201646730. Epub 2017 Jul 26.

PMID:
28667750
9.

Generation of precursor, immature, and mature murine B1-cell lines from c-myc/bcl-xL-overexpressing pre-BI cells.

Wolf I, Bouquet C, Naumann F, Melchers F.

Eur J Immunol. 2017 May;47(5):911-920. doi: 10.1002/eji.201746937. Epub 2017 Apr 6.

10.

Human and Mouse Hematopoietic Stem Cells Are a Depot for Dormant Mycobacterium tuberculosis.

Tornack J, Reece ST, Bauer WM, Vogelzang A, Bandermann S, Zedler U, Stingl G, Kaufmann SH, Melchers F.

PLoS One. 2017 Jan 3;12(1):e0169119. doi: 10.1371/journal.pone.0169119. eCollection 2017.

11.

cDNA-library testing identifies transforming genes cooperating with c-myc in mouse pre-B cells.

Wolf I, Bouquet C, Melchers F.

Eur J Immunol. 2016 Nov;46(11):2555-2565. doi: 10.1002/eji.201646419. Epub 2016 Sep 14.

12.

B-Lymphopoiesis in Fetal Liver, Guided by Chemokines.

Kajikhina K, Tsuneto M, Melchers F.

Adv Immunol. 2016;132:71-89. doi: 10.1016/bs.ai.2016.07.002. Epub 2016 Aug 5. Review.

PMID:
27769508
13.

IL-7 and immobilized Kit-ligand stimulate serum- and stromal cell-free cultures of precursor B-cell lines and clones.

Kawano Y, Petkau G, Wolf I, Tornack J, Melchers F.

Eur J Immunol. 2017 Jan;47(1):206-212. doi: 10.1002/eji.201646677. Epub 2016 Nov 11.

14.

Remembering antibodies coming of age.

Melchers F.

Eur J Immunol. 2016 Jan;46(1):44-51. doi: 10.1002/eji.201545657.

15.

Environments of hematopoiesis and B-lymphopoiesis in foetal liver.

Kajikhina K, Tsuneto M, Melchers F.

Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 92):S91-3. Epub 2015 Oct 12. Review.

PMID:
26457725
16.

Chemokine polyreactivity of IL7Rα+CSF-1R+ lympho-myeloid progenitors in the developing fetal liver.

Kajikhina K, Melchers F, Tsuneto M.

Sci Rep. 2015 Aug 3;5:12817. doi: 10.1038/srep12817.

17.

Checkpoints that control B cell development.

Melchers F.

J Clin Invest. 2015 Jun;125(6):2203-10. doi: 10.1172/JCI78083. Epub 2015 May 4. Review.

18.

Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription.

Sercan Alp Ö, Durlanik S, Schulz D, McGrath M, Grün JR, Bardua M, Ikuta K, Sgouroudis E, Riedel R, Zehentmeier S, Hauser AE, Tsuneto M, Melchers F, Tokoyoda K, Chang HD, Thiel A, Radbruch A.

Eur J Immunol. 2015 Apr;45(4):975-87. doi: 10.1002/eji.201445295. Epub 2015 Feb 27.

19.

BILL-cadherin/cadherin-17 contributes to the survival of memory B cells.

Funakoshi S, Shimizu T, Numata O, Ato M, Melchers F, Ohnishi K.

PLoS One. 2015 Jan 22;10(1):e0117566. doi: 10.1371/journal.pone.0117566. eCollection 2015.

20.

Reprint of: Environments of B cell development.

Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, Grützkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K, Melchers F.

Immunol Lett. 2014 Aug;160(2):109-12. doi: 10.1016/j.imlet.2014.05.005. Epub 2014 May 20.

PMID:
24852107
21.

The amount of self-antigen determines the effector function of murine T cells escaping negative selection.

Swee LK, Nusser A, Curti M, Kreuzaler M, Rolink H, Terracciano L, Melchers F, Andersson J, Rolink A.

Eur J Immunol. 2014 May;44(5):1299-312. doi: 10.1002/eji.201343840. Epub 2014 Mar 7.

22.

Environments of B cell development.

Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, Grützkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K, Melchers F.

Immunol Lett. 2014 Jan-Feb;157(1-2):60-3. doi: 10.1016/j.imlet.2013.11.011. Epub 2013 Nov 24. Review.

PMID:
24284375
23.

Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.

Tornack J, Seiler K, Grützkau A, Grün JR, Onodera M, Melchers F, Tsuneto M.

PLoS One. 2013 Jul 29;8(7):e70116. doi: 10.1371/journal.pone.0070116. Print 2013.

24.

miR-221 redirects precursor B cells to the BM and regulates their residence.

Knoll M, Simmons S, Bouquet C, Grün JR, Melchers F.

Eur J Immunol. 2013 Sep;43(9):2497-506. doi: 10.1002/eji.201343367. Epub 2013 Jul 8.

25.

B-cell progenitors and precursors change their microenvironment in fetal liver during early development.

Tsuneto M, Tokoyoda K, Kajikhina E, Hauser AE, Hara T, Tani-Ichi S, Ikuta K, Melchers F.

Stem Cells. 2013 Dec;31(12):2800-12. doi: 10.1002/stem.1421.

26.

Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.

Simmons S, Knoll M, Drewell C, Wolf I, Mollenkopf HJ, Bouquet C, Melchers F.

Blood. 2012 Nov 1;120(18):3688-98. doi: 10.1182/blood-2012-03-414821. Epub 2012 Aug 27.

27.

The non-Ig parts of the VpreB and λ5 proteins of the surrogate light chain play opposite roles in the surface representation of the precursor B cell receptor.

Knoll M, Yanagisawa Y, Simmons S, Engels N, Wienands J, Melchers F, Ohnishi K.

J Immunol. 2012 Jun 15;188(12):6010-7. doi: 10.4049/jimmunol.1200071. Epub 2012 May 7.

28.

Reprogramming to iPS cells and their subsequent hematopoietic differentiation is more efficient from MEFs than from preB cells.

Reimer A, Seiler K, Tornack J, Tsuneto M, Melchers F.

Immunol Lett. 2012 Mar 30;143(1):70-6. doi: 10.1016/j.imlet.2012.01.012. Epub 2012 Jan 31.

PMID:
22313949
29.

Experimental limitations using reprogrammed cells for hematopoietic differentiation.

Seiler K, Tsuneto M, Melchers F.

J Biomed Biotechnol. 2011;2011:895086. doi: 10.1155/2011/895086. Epub 2011 Nov 30. Review.

30.

The Basel Institute for Immunology.

Melchers F.

Annu Rev Immunol. 2012;30:23-38. doi: 10.1146/annurev-immunol-020711-074912. Epub 2011 Nov 30.

PMID:
22136166
31.

Pim1 and Myc reversibly transform murine precursor B lymphocytes but not mature B lymphocytes.

Bouquet C, Melchers F.

Eur J Immunol. 2012 Feb;42(2):522-32. doi: 10.1002/eji.201141987. Epub 2011 Dec 19.

32.

Induced pluripotent stem cells expressing elevated levels of sox-2, oct-4, and klf-4 are severely reduced in their differentiation from mesodermal to hematopoietic progenitor cells.

Seiler K, Soroush Noghabi M, Karjalainen K, Hummel M, Melchers F, Tsuneto M.

Stem Cells Dev. 2011 Jul;20(7):1131-42. doi: 10.1089/scd.2010.0391. Epub 2011 Feb 24.

PMID:
21348597
33.

Long-term "in vitro" proliferating mouse hematopoietic progenitor cell lines.

Vegh P, Winckler J, Melchers F.

Immunol Lett. 2010 May 4;130(1-2):32-5. doi: 10.1016/j.imlet.2010.02.001. Epub 2010 Feb 17.

PMID:
20170678
34.

Pillars article: a critical role of lambda 5 protein in B cell development. Cell. 1992. 69: 823-831.

Kitamura D, Kudo A, Schaal S, Müller W, Melchers F, Rajewsky K.

J Immunol. 2010 Feb 1;184(3):1130-8. No abstract available.

35.

Checkpoints in lymphocyte development and autoimmune disease.

von Boehmer H, Melchers F.

Nat Immunol. 2010 Jan;11(1):14-20. doi: 10.1038/ni.1794. Epub 2009 Dec 17. Review.

PMID:
20016505
36.

[From stem cells to lymphocytes].

Melchers F.

Z Rheumatol. 2009 May;68(3):196-200, 202-4. doi: 10.1007/s00393-008-0390-6. Review. German.

PMID:
19384553
37.

In Memoriam: János Gergely (1925-2008).

Erdei A, Melchers F.

Eur J Immunol. 2008 Jun;38(6):1476-8. doi: 10.1002/eji.200890021. No abstract available.

38.

Starting at the end.

Melchers F.

Eur J Immunol. 2007 Nov;37 Suppl 1:S125-33.

39.

Neutrality, compensation, and negative selection during evolution of B-cell development transcriptomes.

Hoffmann R, Lottaz C, Kühne T, Rolink A, Melchers F.

Mol Biol Evol. 2007 Dec;24(12):2610-8. Epub 2007 Sep 21.

PMID:
17890238
40.

Rules for the rearrangement events at the L chain gene loci of the mouse.

Melchers F, Yamagami T, Rolink A, Andersson J.

Adv Exp Med Biol. 2007;596:63-70. Review. No abstract available.

PMID:
17338176
41.

Anergic B cells caught in the act.

Melchers F.

Immunity. 2006 Dec;25(6):864-7. Review.

42.

B cell tolerance--how to make it and how to break it.

Melchers F, Rolink AR.

Curr Top Microbiol Immunol. 2006;305:1-23. Review.

PMID:
16724798
43.

Only VpreB1, but not VpreB2, is expressed at levels which allow normal development of B cells.

Mundt C, Licence S, Maxwell G, Melchers F, Mårtensson IL.

Int Immunol. 2006 Jan;18(1):163-72. Epub 2005 Dec 16.

PMID:
16361315
44.
45.
46.

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells.

Ardouin L, Rolink AG, Mura AM, Gommeaux J, Melchers F, Busslinger M, Malissen M, Malissen B.

Eur J Immunol. 2005 Mar;35(3):977-86.

47.
48.

The death of a dogma?

Melchers F.

Nat Immunol. 2004 Dec;5(12):1199-201. No abstract available.

PMID:
15549116
49.

Molecular mechanisms guiding late stages of B-cell development.

Rolink AG, Andersson J, Melchers F.

Immunol Rev. 2004 Feb;197:41-50. Review.

PMID:
14962185
50.

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