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Items: 1 to 50 of 116

1.

A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets.

Klanert G, Fernandez DJ, Weinguny M, Eisenhut P, Bühler E, Melcher M, Titus SA, Diendorfer AB, Gludovacz E, Jadhav V, Xiao S, Stern B, Lal M, Shiloach J, Borth N.

Sci Rep. 2019 Jun 18;9(1):8689. doi: 10.1038/s41598-019-45159-2.

2.

Underrepresented Minorities are Underrepresented Among General Surgery Applicants Selected to Interview.

Jarman BT, Kallies KJ, Joshi ART, Smink DS, Sarosi GA, Chang L, Green JM, Greenberg JA, Melcher ML, Nfonsam V, Ramirez LD, Borgert AJ, Whiting J.

J Surg Educ. 2019 Jun 5. pii: S1931-7204(19)30214-4. doi: 10.1016/j.jsurg.2019.05.018. [Epub ahead of print]

PMID:
31175064
3.

Matching Kidneys with Priority in Kidney Exchange Programs.

Liu W, Melcher ML.

Med Decis Making. 2019 May;39(4):335-345. doi: 10.1177/0272989X19849457. Epub 2019 May 29.

PMID:
31142192
4.

Prediction of the Quantity and Purity of an Antibody Capture Process in Real Time.

Walch N, Scharl T, Felföldi E, Sauer DG, Melcher M, Leisch F, Dürauer A, Jungbauer A.

Biotechnol J. 2019 Jul;14(7):e1800521. doi: 10.1002/biot.201800521. Epub 2019 May 20.

PMID:
30945440
5.

Real-time monitoring and model-based prediction of purity and quantity during a chromatographic capture of fibroblast growth factor 2.

Sauer DG, Melcher M, Mosor M, Walch N, Berkemeyer M, Scharl-Hirsch T, Leisch F, Jungbauer A, Dürauer A.

Biotechnol Bioeng. 2019 Apr 1. doi: 10.1002/bit.26984. [Epub ahead of print]

PMID:
30934111
6.

Reducing the Burden of Fellowship Interviews-Reply.

Melcher ML, Ashlagi I, Wapnir I.

JAMA. 2019 Mar 19;321(11):1107. doi: 10.1001/jama.2018.21596. No abstract available.

PMID:
30874752
7.

Pathologic Response to Pretransplant Locoregional Therapy is Predictive of Patient Outcome After Liver Transplantation for Hepatocellular Carcinoma: Analysis From the US Multicenter HCC Transplant Consortium.

DiNorcia J, Florman SS, Haydel B, Tabrizian P, Ruiz RM, Klintmalm GB, Senguttuvan S, Lee DD, Taner CB, Verna EC, Halazun KJ, Hoteit M, Levine MH, Chapman WC, Vachharajani N, Aucejo F, Nguyen MH, Melcher ML, Tevar AD, Humar A, Mobley C, Ghobrial M, Nydam TL, Amundsen B, Markmann JF, Berumen J, Hemming AW, Langnas AN, Carney CA, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Markovic D, Busuttil RW, Agopian VG.

Ann Surg. 2019 Mar 5. doi: 10.1097/SLA.0000000000003253. [Epub ahead of print]

PMID:
30870180
8.

A comparison of statistical learning methods for deriving determining factors of accident occurrence from an imbalanced high resolution dataset.

Schlögl M, Stütz R, Laaha G, Melcher M.

Accid Anal Prev. 2019 Jun;127:134-149. doi: 10.1016/j.aap.2019.02.008. Epub 2019 Mar 8.

PMID:
30856396
9.

Transient manipulation of the expression level of selected growth rate correlating microRNAs does not increase growth rate in CHO-K1 cells.

Klanert G, Bydlinski N, Agu P, Diendorfer AB, Hackl M, Hanscho M, Melcher M, Baumann M, Grillari J, Borth N.

J Biotechnol. 2019 Apr 10;295:63-70. doi: 10.1016/j.jbiotec.2019.02.011. Epub 2019 Mar 7.

PMID:
30853633
10.

May the Interview Be With You: Signal Your Preferences.

Melcher ML, Wapnir I, Ashlagi I.

J Grad Med Educ. 2019 Feb;11(1):39-40. doi: 10.4300/JGME-D-19-00002.1. No abstract available.

PMID:
30805095
11.

Living Kidney Donation: Strategies to Increase the Donor Pool.

Lee LY, Pham TA, Melcher ML.

Surg Clin North Am. 2019 Feb;99(1):37-47. doi: 10.1016/j.suc.2018.09.003. Review.

PMID:
30471740
12.

Matching for Fellowship Interviews.

Melcher ML, Ashlagi I, Wapnir I.

JAMA. 2018 Oct 23;320(16):1639-1640. doi: 10.1001/jama.2018.13080. No abstract available.

PMID:
30422279
13.

Liver transplantation for hepatitis C virus (HCV) non-viremic recipients with HCV viremic donors.

Kwong AJ, Wall A, Melcher M, Wang U, Ahmed A, Subramanian A, Kwo PY.

Am J Transplant. 2019 May;19(5):1380-1387. doi: 10.1111/ajt.15162. Epub 2018 Nov 26.

PMID:
30378723
14.

Socioeconomic Status in Non-directed and Voucher-based Living Kidney Donation.

Nassiri N, Baskin AS, Herbert LK, Connor S, Pham T, Melcher ML, Sinacore J, Veale JL.

Eur Urol Focus. 2018 Mar;4(2):185-189. doi: 10.1016/j.euf.2018.07.020. Epub 2018 Aug 16. Review.

PMID:
30122635
15.

Structured Reporting of Multiphasic CT for Hepatocellular Carcinoma: Effect on Staging and Suitability for Transplant.

Poullos PD, Tseng JJ, Melcher ML, Concepcion W, Loening AM, Rosenberg J, Willmann JK.

AJR Am J Roentgenol. 2018 Apr;210(4):766-774. doi: 10.2214/AJR.17.18725. Epub 2018 Feb 22.

PMID:
29470153
16.

Candidatus Nitrosocaldus cavascurensis, an Ammonia Oxidizing, Extremely Thermophilic Archaeon with a Highly Mobile Genome.

Abby SS, Melcher M, Kerou M, Krupovic M, Stieglmeier M, Rossel C, Pfeifer K, Schleper C.

Front Microbiol. 2018 Jan 26;9:28. doi: 10.3389/fmicb.2018.00028. eCollection 2018.

17.

Changes in Chromosome Counts and Patterns in CHO Cell Lines upon Generation of Recombinant Cell Lines and Subcloning.

Vcelar S, Melcher M, Auer N, Hrdina A, Puklowski A, Leisch F, Jadhav V, Wenger T, Baumann M, Borth N.

Biotechnol J. 2018 Mar;13(3):e1700495. doi: 10.1002/biot.201700495. Epub 2018 Feb 1.

PMID:
29328552
18.

Shipping living donor kidneys and transplant recipient outcomes.

Treat E, Chow EKH, Peipert JD, Waterman A, Kwan L, Massie AB, Thomas AG, Bowring MG, Leeser D, Flechner S, Melcher ML, Kapur S, Segev DL, Veale J.

Am J Transplant. 2018 Mar;18(3):632-641. doi: 10.1111/ajt.14597. Epub 2017 Dec 18.

19.

Control of Enantioselectivity in Rhodium(I) Catalysis by Planar Chiral Dibenzo[a,e]cyclooctatetraenes.

Melcher MC, Ivšić T, Olagnon C, Tenten C, Lützen A, Strand D.

Chemistry. 2018 Feb 16;24(10):2344-2348. doi: 10.1002/chem.201704816. Epub 2017 Dec 14.

PMID:
29131428
20.

Effect of match-run frequencies on the number of transplants and waiting times in kidney exchange.

Ashlagi I, Bingaman A, Burq M, Manshadi V, Gamarnik D, Murphey C, Roth AE, Melcher ML, Rees MA.

Am J Transplant. 2018 May;18(5):1177-1186. doi: 10.1111/ajt.14566. Epub 2017 Dec 5.

21.

Preparation for the Diversity of 21st Century Surgical Leadership Opportunities Demands Diverse Opportunities for "Professional Development".

Melcher ML, Greco RS, Krummel TM, Morris AM, Hawn MT.

Ann Surg. 2018 Dec;268(6):e52-e53. doi: 10.1097/SLA.0000000000002470. No abstract available.

PMID:
29064907
22.

Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting.

Vcelar S, Jadhav V, Melcher M, Auer N, Hrdina A, Sagmeister R, Heffner K, Puklowski A, Betenbaugh M, Wenger T, Leisch F, Baumann M, Borth N.

Biotechnol Bioeng. 2018 Jan;115(1):165-173. doi: 10.1002/bit.26453.

PMID:
28921524
23.

Hospital readmissions following HLA-incompatible live donor kidney transplantation: A multi-center study.

Orandi BJ, Luo X, King EA, Garonzik-Wang JM, Bae S, Montgomery RA, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Segev DL.

Am J Transplant. 2018 Mar;18(3):650-658. doi: 10.1111/ajt.14472. Epub 2017 Sep 23.

24.

Association of General Surgery Resident Remediation and Program Director Attitudes With Resident Attrition.

Schwed AC, Lee SL, Salcedo ES, Reeves ME, Inaba K, Sidwell RA, Amersi F, Are C, Arnell TD, Damewood RB, Dent DL, Donahue T, Gauvin J, Hartranft T, Jacobsen GR, Jarman BT, Melcher ML, Mellinger JD, Morris JB, Nehler M, Smith BR, Wolfe M, Kaji AH, de Virgilio C.

JAMA Surg. 2017 Dec 1;152(12):1134-1140. doi: 10.1001/jamasurg.2017.2656.

25.

Pilot evaluation of the Computer-Based Assessment for Sampling Personal Characteristics test.

Shipper ES, Mazer LM, Merrell SB, Lin DT, Lau JN, Melcher ML.

J Surg Res. 2017 Jul;215:211-218. doi: 10.1016/j.jss.2017.03.054. Epub 2017 Apr 6.

PMID:
28688650
26.

A Multicenter Prospective Comparison of the Accreditation Council for Graduate Medical Education Milestones: Clinical Competency Committee vs. Resident Self-Assessment.

Watson RS, Borgert AJ, O Heron CT, Kallies KJ, Sidwell RA, Mellinger JD, Joshi AR, Galante JM, Chambers LW, Morris JB, Josloff RK, Melcher ML, Fuhrman GM, Terhune KP, Chang L, Ferguson EM, Auyang ED, Patel KR, Jarman BT.

J Surg Educ. 2017 Nov - Dec;74(6):e8-e14. doi: 10.1016/j.jsurg.2017.06.009. Epub 2017 Jun 27.

PMID:
28666959
27.

Impact of Pretransplant Bridging Locoregional Therapy for Patients With Hepatocellular Carcinoma Within Milan Criteria Undergoing Liver Transplantation: Analysis of 3601 Patients From the US Multicenter HCC Transplant Consortium.

Agopian VG, Harlander-Locke MP, Ruiz RM, Klintmalm GB, Senguttuvan S, Florman SS, Haydel B, Hoteit M, Levine MH, Lee DD, Taner CB, Verna EC, Halazun KJ, Abdelmessih R, Tevar AD, Humar A, Aucejo F, Chapman WC, Vachharajani N, Nguyen MH, Melcher ML, Nydam TL, Mobley C, Ghobrial RM, Amundsen B, Markmann JF, Langnas AN, Carney CA, Berumen J, Hemming AW, Sudan DL, Hong JC, Kim J, Zimmerman MA, Rana A, Kueht ML, Jones CM, Fishbein TM, Busuttil RW.

Ann Surg. 2017 Sep;266(3):525-535. doi: 10.1097/SLA.0000000000002381.

PMID:
28654545
28.

Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells.

Melcher M, Danhauser K, Seibt A, Degistirici Ö, Baertling F, Kondadi AK, Reichert AS, Koopman WJH, Willems PHGM, Rodenburg RJ, Mayatepek E, Meisel R, Distelmaier F.

Stem Cell Res Ther. 2017 Jun 24;8(1):150. doi: 10.1186/s13287-017-0601-7.

29.

The Incremental Cost of Incompatible Living Donor Kidney Transplantation: A National Cohort Analysis.

Axelrod D, Lentine KL, Schnitzler MA, Luo X, Xiao H, Orandi BJ, Massie A, Garonzik-Wang J, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Osama Gaber A, Montgomery RA, Segev DL.

Am J Transplant. 2017 Dec;17(12):3123-3130. doi: 10.1111/ajt.14392. Epub 2017 Jul 21.

30.

Advanced Donation Programs and Deceased Donor-Initiated Chains-2 Innovations in Kidney Paired Donation.

Wall AE, Veale JL, Melcher ML.

Transplantation. 2017 Dec;101(12):2818-2824. doi: 10.1097/TP.0000000000001838. Review.

PMID:
28574902
31.

A multi-institution analysis of general surgery resident peer-reviewed publication trends.

Forrester JD, Ansari P, Are C, Auyang E, Galante JM, Jarman BT, Smith BR, Watkins AC, Melcher ML.

J Surg Res. 2017 Apr;210:92-98. doi: 10.1016/j.jss.2016.11.015. Epub 2016 Nov 10.

PMID:
28457346
32.

Kidney paired exchange and desensitization: Strategies to transplant the difficult to match kidney patients with living donors.

Pham TA, Lee JI, Melcher ML.

Transplant Rev (Orlando). 2017 Jan;31(1):29-34. doi: 10.1016/j.trre.2017.01.003. Epub 2017 Jan 24. Review.

PMID:
28284304
33.

Proteomics and comparative genomics of Nitrososphaera viennensis reveal the core genome and adaptations of archaeal ammonia oxidizers.

Kerou M, Offre P, Valledor L, Abby SS, Melcher M, Nagler M, Weckwerth W, Schleper C.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7937-E7946. Epub 2016 Nov 18.

34.

HLA Matching Trumps Donor Age: Donor-Recipient Pairing Characteristics That Impact Long-Term Success in Living Donor Kidney Transplantation in the Era of Paired Kidney Exchange.

Milner J, Melcher ML, Lee B, Veale J, Ronin M, D'Alessandro T, Hil G, Fry PC, Shannon PW.

Transplant Direct. 2016 Jun 6;2(7):e85. eCollection 2016 Jul.

35.

Boosted structured additive regression for Escherichia coli fed-batch fermentation modeling.

Melcher M, Scharl T, Luchner M, Striedner G, Leisch F.

Biotechnol Bioeng. 2017 Feb;114(2):321-334. doi: 10.1002/bit.26073. Epub 2016 Aug 30.

PMID:
27530968
36.

We Need to Take the Next Step.

Melcher ML, Roberts JP, Leichtman AB, Roth AE, Rees MA.

Am J Transplant. 2016 Dec;16(12):3581-3582. doi: 10.1111/ajt.14008. Epub 2016 Sep 12. No abstract available.

37.

Accelerated Nucleation of Hydroxyapatite Using an Engineered Hydrophobin Fusion Protein.

Melcher M, Facey SJ, Henkes TM, Subkowski T, Hauer B.

Biomacromolecules. 2016 May 9;17(5):1716-26. doi: 10.1021/acs.biomac.6b00135. Epub 2016 Apr 5.

PMID:
27010648
38.

Survival Benefit with Kidney Transplants from HLA-Incompatible Live Donors.

Orandi BJ, Luo X, Massie AB, Garonzik-Wang JM, Lonze BE, Ahmed R, Van Arendonk KJ, Stegall MD, Jordan SC, Oberholzer J, Dunn TB, Ratner LE, Kapur S, Pelletier RP, Roberts JP, Melcher ML, Singh P, Sudan DL, Posner MP, El-Amm JM, Shapiro R, Cooper M, Lipkowitz GS, Rees MA, Marsh CL, Sankari BR, Gerber DA, Nelson PW, Wellen J, Bozorgzadeh A, Gaber AO, Montgomery RA, Segev DL.

N Engl J Med. 2016 Mar 10;374(10):940-50. doi: 10.1056/NEJMoa1508380.

39.

Prehabilitation in our most frail surgical patients: are wearable fitness devices the next frontier?

Rumer KK, Saraswathula A, Melcher ML.

Curr Opin Organ Transplant. 2016 Apr;21(2):188-93. doi: 10.1097/MOT.0000000000000295. Review.

PMID:
26859220
40.

Utilization of Deceased Donor Kidneys to Initiate Living Donor Chains.

Melcher ML, Roberts JP, Leichtman AB, Roth AE, Rees MA.

Am J Transplant. 2016 May;16(5):1367-70. doi: 10.1111/ajt.13740. Epub 2016 Mar 9.

41.

EARS2 mutations cause fatal neonatal lactic acidosis, recurrent hypoglycemia and agenesis of corpus callosum.

Danhauser K, Haack TB, Alhaddad B, Melcher M, Seibt A, Strom TM, Meitinger T, Klee D, Mayatepek E, Prokisch H, Distelmaier F.

Metab Brain Dis. 2016 Jun;31(3):717-21. doi: 10.1007/s11011-016-9793-2. Epub 2016 Jan 16.

PMID:
26780086
42.

Human thioredoxin 2 deficiency impairs mitochondrial redox homeostasis and causes early-onset neurodegeneration.

Holzerova E, Danhauser K, Haack TB, Kremer LS, Melcher M, Ingold I, Kobayashi S, Terrile C, Wolf P, Schaper J, Mayatepek E, Baertling F, Friedmann Angeli JP, Conrad M, Strom TM, Meitinger T, Prokisch H, Distelmaier F.

Brain. 2016 Feb;139(Pt 2):346-54. doi: 10.1093/brain/awv350. Epub 2015 Dec 1.

PMID:
26626369
43.

Is Informed Consent Enough?

Liu W, Krawiec KD, Melcher ML.

Am J Transplant. 2016 Mar;16(3):1038. doi: 10.1111/ajt.13615. Epub 2016 Jan 14. No abstract available.

44.

Program Factors That Influence American Board of Surgery In-Training Examination Performance: A Multi-Institutional Study.

Kim JJ, Gifford ED, Moazzez A, Sidwell RA, Reeves ME, Hartranft TH, Inaba K, Jarman BT, Are C, Galante JM, Amersi F, Smith BR, Melcher ML, Nelson MT, Donahue T, Jacobsen G, Arnell TD, Lee S, Neville A, de Virgilio C.

J Surg Educ. 2015 Nov-Dec;72(6):e236-42. doi: 10.1016/j.jsurg.2015.06.014. Epub 2015 Aug 28.

PMID:
26319103
45.

Saving Supersick Patients Undergoing Liver Transplant.

Melcher ML.

JAMA Surg. 2015 Nov;150(11):1073. doi: 10.1001/jamasurg.2015.1881. No abstract available.

PMID:
26309213
46.

Reading Habits of General Surgery Residents and Association With American Board of Surgery In-Training Examination Performance.

Kim JJ, Kim DY, Kaji AH, Gifford ED, Reid C, Sidwell RA, Reeves ME, Hartranft TH, Inaba K, Jarman BT, Are C, Galante JM, Amersi F, Smith BR, Melcher ML, Nelson MT, Donahue T, Jacobsen G, Arnell TD, de Virgilio C.

JAMA Surg. 2015 Sep;150(9):882-9. doi: 10.1001/jamasurg.2015.1698.

PMID:
26176352
47.

The potential of random forest and neural networks for biomass and recombinant protein modeling in Escherichia coli fed-batch fermentations.

Melcher M, Scharl T, Spangl B, Luchner M, Cserjan M, Bayer K, Leisch F, Striedner G.

Biotechnol J. 2015 Sep;10(11):1770-82. doi: 10.1002/biot.201400790. Epub 2015 Aug 11.

PMID:
26121295
48.

Structure-activity studies in the development of a hydrazone based inhibitor of adipose-triglyceride lipase (ATGL).

Mayer N, Schweiger M, Melcher MC, Fledelius C, Zechner R, Zimmermann R, Breinbauer R.

Bioorg Med Chem. 2015 Jun 15;23(12):2904-16. doi: 10.1016/j.bmc.2015.02.051. Epub 2015 Mar 5.

49.

Identifying Opportunities to Increase the Throughput of Kidney Paired Donation.

Liu W, Treat E, Veale JL, Milner J, Melcher ML.

Transplantation. 2015 Jul;99(7):1410-5. doi: 10.1097/TP.0000000000000527.

PMID:
25606799
50.

Iridium catalyzed carbocyclizations: efficient (5+2) cycloadditions of vinylcyclopropanes and alkynes.

Melcher MC, von Wachenfeldt H, Sundin A, Strand D.

Chemistry. 2015 Jan 7;21(2):531-5. doi: 10.1002/chem.201405729. Epub 2014 Nov 20.

PMID:
25413863

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