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Chronic Obstructive Pulmonary Disease and Risk of Mortality in Patients with Venous Thromboembolism-The Tromsø Study.

Børvik T, Brækkan SK, Evensen LH, Brodin EE, Morelli VM, Melbye H, Hansen JB.

Thromb Haemost. 2019 Dec 30. doi: 10.1055/s-0039-3400744. [Epub ahead of print]


Prevalence and clinical associations of wheezes and crackles in the general population: the Tromsø study.

Aviles-Solis JC, Jácome C, Davidsen A, Einarsen R, Vanbelle S, Pasterkamp H, Melbye H.

BMC Pulm Med. 2019 Sep 11;19(1):173. doi: 10.1186/s12890-019-0928-1.


C-Reactive Protein Testing to Guide Antibiotic Prescribing for COPD Exacerbations.

Butler CC, Gillespie D, White P, Bates J, Lowe R, Thomas-Jones E, Wootton M, Hood K, Phillips R, Melbye H, Llor C, Cals JWL, Naik G, Kirby N, Gal M, Riga E, Francis NA.

N Engl J Med. 2019 Jul 11;381(2):111-120. doi: 10.1056/NEJMoa1803185.


Convolutional Neural Network for Breathing Phase Detection in Lung Sounds.

Jácome C, Ravn J, Holsbø E, Aviles-Solis JC, Melbye H, Ailo Bongo L.

Sensors (Basel). 2019 Apr 15;19(8). pii: E1798. doi: 10.3390/s19081798.


Antibiotic Prescribing for Acute Respiratory Tract Infections 12 Months After Communication and CRP Training: A Randomized Trial.

Little P, Stuart B, Francis N, Douglas E, Tonkin-Crine S, Anthierens S, Cals JWL, Melbye H, Santer M, Moore M, Coenen S, Butler CC, Hood K, Kelson M, Godycki-Cwirko M, Mierzecki A, Torres A, Llor C, Davies M, Mullee M, O'Reilly G, van der Velden A, Geraghty AWA, Goossens H, Verheij T, Yardley L; GRACE consortium.

Ann Fam Med. 2019 Mar;17(2):125-132. doi: 10.1370/afm.2356.


På tide med nye referanseverdier og grenseverdier for spirometri.

Langhammer A, Crowley S, Humerfelt S, Melbye H, Nag T, Svanes Ø.

Tidsskr Nor Laegeforen. 2018 Sep 3;138(13). doi: 10.4045/tidsskr.18.0345. Print 2018 Sep 4. Norwegian. No abstract available.


Adventitious and Normal Lung Sounds in the General Population: Comparison of Standardized and Spontaneous Breathing.

Jácome C, Aviles-Solis JC, Uhre ÅM, Pasterkamp H, Melbye H.

Respir Care. 2018 Nov;63(11):1379-1387. doi: 10.4187/respcare.06121. Epub 2018 Aug 7.


Impaired left ventricular filling is associated with decreased pulse oximetry values.

Dalbak LG, Schirmer H, Straand J, Mdala I, Solberg OG, Melbye H.

Scand Cardiovasc J. 2018 Aug;52(4):211-217. doi: 10.1080/14017431.2018.1464662. Epub 2018 Apr 19.


International perception of lung sounds: a comparison of classification across some European borders.

Aviles-Solis JC, Vanbelle S, Halvorsen PA, Francis N, Cals JWL, Andreeva EA, Marques A, Piirilä P, Pasterkamp H, Melbye H.

BMJ Open Respir Res. 2017 Dec 18;4(1):e000250. doi: 10.1136/bmjresp-2017-000250. eCollection 2017.


General practitioner use of a C-reactive protein point-of-care test to help target antibiotic prescribing in patients with acute exacerbations of chronic obstructive pulmonary disease (the PACE study): study protocol for a randomised controlled trial.

Bates J, Francis NA, White P, Gillespie D, Thomas-Jones E, Breen R, Kirby N, Hood K, Gal M, Phillips R, Naik G, Cals J, Llor C, Melbye H, Wootton M, Riga E, Cochrane A, Howe R, Fitzsimmons D, Sewell B, Alam MF, Butler CC.

Trials. 2017 Sep 29;18(1):442. doi: 10.1186/s13063-017-2144-8.


Why do physicians lack engagement with smoking cessation treatment in their COPD patients? A multinational qualitative study.

van Eerd EAM, Bech Risør M, Spigt M, Godycki-Cwirko M, Andreeva E, Francis N, Wollny A, Melbye H, van Schayck O, Kotz D.

NPJ Prim Care Respir Med. 2017 Jun 23;27(1):41. doi: 10.1038/s41533-017-0038-6.


Drop in lung function during asthma and COPD exacerbations - can it be assessed without spirometry?

Melbye H, Al-Ani S, Spigt M.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 8;11:3145-3152. eCollection 2016.


How do general practitioners implement decision-making regarding COPD patients with exacerbations? An international focus group study.

Laue J, Melbye H, Halvorsen PA, Andreeva EA, Godycki-Cwirko M, Wollny A, Francis NA, Spigt M, Kung K, Risør MB.

Int J Chron Obstruct Pulmon Dis. 2016 Dec 8;11:3109-3119. eCollection 2016.


Global Lung Function Initiative 2012 reference equations for spirometry in the Norwegian population.

Langhammer A, Johannessen A, Holmen TL, Melbye H, Stanojevic S, Lund MB, Melsom MN, Bakke P, Quanjer PH.

Eur Respir J. 2016 Dec;48(6):1602-1611. doi: 10.1183/13993003.00443-2016. Epub 2016 Oct 6.


Family Practitioners' Advice about Taking Time Off Work for Lower Respiratory Tract Infections: A Prospective Study in Twelve European Primary Care Networks.

Godycki-Cwirko M, Nocun M, Butler CC, Little P, Verheij T, Hood K, Fleten N, Kowalczyk A, Melbye H.

PLoS One. 2016 Oct 19;11(10):e0164779. doi: 10.1371/journal.pone.0164779. eCollection 2016.


The added value of C-reactive protein measurement in diagnosing pneumonia in primary care: a meta-analysis of individual patient data.

Minnaard MC, de Groot JAH, Hopstaken RM, Schierenberg A, de Wit NJ, Reitsma JB, Broekhuizen BDL, van Vugt SF, Neven AK, Graffelman AW, Melbye H, Rainer TH, Steurer J, Holm A, Gonzales R, Dinant GJ, van de Pol AC, Verheij TJM.

CMAJ. 2017 Jan 16;189(2):E56-E63. doi: 10.1503/cmaj.151163. Epub 2016 Sep 19.


Patient experiences and the association with organizational factors in general practice: results from the Norwegian part of the international, multi-centre, cross-sectional QUALICOPC study.

Eide TB, Straand J, Melbye H, Rortveit G, Hetlevik I, Rosvold EO.

BMC Health Serv Res. 2016 Aug 24;16(1):428. doi: 10.1186/s12913-016-1684-z.


A new diagnosis of asthma or COPD is linked to smoking cessation - the Tromsø study.

Danielsen SE, Løchen ML, Medbø A, Vold ML, Melbye H.

Int J Chron Obstruct Pulmon Dis. 2016 Jun 30;11:1453-8. doi: 10.2147/COPD.S108046. eCollection 2016.


GP utilisation by education level among adults with COPD or asthma: a cross-sectional register-based study.

Hetlevik Ø, Melbye H, Gjesdal S.

NPJ Prim Care Respir Med. 2016 Jun 9;26:16027. doi: 10.1038/npjpcrm.2016.27.


Wheezes, crackles and rhonchi: simplifying description of lung sounds increases the agreement on their classification: a study of 12 physicians' classification of lung sounds from video recordings.

Melbye H, Garcia-Marcos L, Brand P, Everard M, Priftis K, Pasterkamp H.

BMJ Open Respir Res. 2016 Apr 28;3(1):e000136. doi: 10.1136/bmjresp-2016-000136. eCollection 2016.


External Validation of Prediction Models for Pneumonia in Primary Care Patients with Lower Respiratory Tract Infection: An Individual Patient Data Meta-Analysis.

Schierenberg A, Minnaard MC, Hopstaken RM, van de Pol AC, Broekhuizen BD, de Wit NJ, Reitsma JB, van Vugt SF, Graffelman AW, Melbye H, Rainer TH, Steurer J, Holm A, Gonzales R, Dinant GJ, de Groot JA, Verheij TJ.

PLoS One. 2016 Feb 26;11(2):e0149895. doi: 10.1371/journal.pone.0149895. eCollection 2016.


Should pulse oximetry be included in GPs' assessment of patients with obstructive lung disease?

Dalbak LG, Straand J, Melbye H.

Scand J Prim Health Care. 2015;33(4):305-10. doi: 10.3109/02813432.2015.1117283. Epub 2015 Dec 11.


Towards the standardisation of lung sound nomenclature.

Pasterkamp H, Brand PL, Everard M, Garcia-Marcos L, Melbye H, Priftis KN.

Eur Respir J. 2016 Mar;47(3):724-32. doi: 10.1183/13993003.01132-2015. Epub 2015 Dec 2.


COPD and risk of venous thromboembolism and mortality in a general population.

Børvik T, Brækkan SK, Enga K, Schirmer H, Brodin EE, Melbye H, Hansen JB.

Eur Respir J. 2016 Feb;47(2):473-81. doi: 10.1183/13993003.00402-2015. Epub 2015 Nov 19.


Low oxygen saturation and mortality in an adult cohort: the Tromsø study.

Vold ML, Aasebø U, Wilsgaard T, Melbye H.

BMC Pulm Med. 2015 Feb 12;15:9. doi: 10.1186/s12890-015-0003-5.


Low FEV1, smoking history, and obesity are factors associated with oxygen saturation decrease in an adult population cohort.

Vold ML, Aasebø U, Melbye H.

Int J Chron Obstruct Pulmon Dis. 2014 Oct 21;9:1225-33. doi: 10.2147/COPD.S69438. eCollection 2014.


Primary and secondary care clinicians' views on self-treatment of COPD exacerbations: a multinational qualitative study.

Davies F, Risør MB, Melbye H, Spigt M, Brookes-Howell L, O'Neill C, Godycki-Cwirko M, Wollny A, Andreeva E, Butler C, Francis N.

Patient Educ Couns. 2014 Aug;96(2):256-63. doi: 10.1016/j.pec.2014.05.011. Epub 2014 May 22.


Predictors of ICS/LABA prescribing in COPD patients: a study from general practice.

Drivenes E, Ostrem A, Melbye H.

BMC Fam Pract. 2014 Mar 5;15:42. doi: 10.1186/1471-2296-15-42.


Medication use in European primary care patients with lower respiratory tract infection: an observational study.

Hamoen M, Broekhuizen BD, Little P, Melbye H, Coenen S, Goossens H, Butler CC, Francis NA, Verheij TJ; GRACE clinical study group.

Br J Gen Pract. 2014 Feb;64(619):e81-91. doi: 10.3399/bjgp14X677130. Review.


The complexity of managing COPD exacerbations: a grounded theory study of European general practice.

Risør MB, Spigt M, Iversen R, Godycki-Cwirko M, Francis N, Altiner A, Andreeva E, Kung K, Melbye H.

BMJ Open. 2013 Dec 5;3(12):e003861. doi: 10.1136/bmjopen-2013-003861.


Would GPs advise patients with respiratory tract infections to refrain from exercise, stay indoors or stay in bed? Survey of GPs in Poland and Norway.

Halvorsen PA, Godycki-Cwirko M, Wennevold K, Melbye H.

Eur J Gen Pract. 2014 Sep;20(3):209-13. doi: 10.3109/13814788.2013.848339. Epub 2013 Nov 13.


Are patient views about antibiotics related to clinician perceptions, management and outcome? A multi-country study in outpatients with acute cough.

Coenen S, Francis N, Kelly M, Hood K, Nuttall J, Little P, Verheij TJ, Melbye H, Goossens H, Butler CC; GRACE Project Group.

PLoS One. 2013 Oct 23;8(10):e76691. doi: 10.1371/journal.pone.0076691. eCollection 2013.


Cross-sectional associations between prevalent vertebral fracture and pulmonary function in the sixth Tromsø study.

Morseth B, Melbye H, Waterloo S, Thomassen MR, Risberg MJ, Emaus N.

BMC Geriatr. 2013 Oct 29;13:116. doi: 10.1186/1471-2318-13-116.


Trust, openness and continuity of care influence acceptance of antibiotics for children with respiratory tract infections: a four country qualitative study.

Brookes-Howell L, Wood F, Verheij T, Prout H, Cooper L, Hood K, Melbye H, Torres A, Godycki-Cwirko M, Fernandez-Vandellos P, Ystgaard MF, Falk Taksdal T, Krawczyk J, Butler CC.

Fam Pract. 2014 Feb;31(1):102-10. doi: 10.1093/fampra/cmt052. Epub 2013 Oct 28.


Predictors of exacerbations of asthma and COPD during one year in primary care.

Al-ani S, Spigt M, Hofset P, Melbye H.

Fam Pract. 2013 Dec;30(6):621-8. doi: 10.1093/fampra/cmt055. Epub 2013 Oct 10.


Should chest examination be reinstated in the early diagnosis of chronic obstructive pulmonary disease?

Oshaug K, Halvorsen PA, Melbye H.

Int J Chron Obstruct Pulmon Dis. 2013;8:369-77. doi: 10.2147/COPD.S47992. Epub 2013 Jul 31.


Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial.

Little P, Stuart B, Francis N, Douglas E, Tonkin-Crine S, Anthierens S, Cals JW, Melbye H, Santer M, Moore M, Coenen S, Butler C, Hood K, Kelly M, Godycki-Cwirko M, Mierzecki A, Torres A, Llor C, Davies M, Mullee M, O'Reilly G, van der Velden A, Geraghty AW, Goossens H, Verheij T, Yardley L; GRACE consortium.

Lancet. 2013 Oct 5;382(9899):1175-82. doi: 10.1016/S0140-6736(13)60994-0. Epub 2013 Jul 31.


Cost-effectiveness of point-of-care C-reactive protein testing to inform antibiotic prescribing decisions.

Oppong R, Jit M, Smith RD, Butler CC, Melbye H, Mölstad S, Coast J.

Br J Gen Pract. 2013 Jul;63(612):e465-71. doi: 10.3399/bjgp13X669185.


Association between serum 25-hydroxyvitamin D concentration and symptoms of respiratory tract infection in a Norwegian population: the Tromsø Study.

Robertsen S, Grimnes G, Melbye H.

Public Health Nutr. 2014 Apr;17(4):780-6. doi: 10.1017/S1368980013001134. Epub 2013 May 9.


Changed terms for drug payment influenced GPs' diagnoses and prescribing practice for inhaled corticosteroids.

Dalbak LG, Rognstad S, Melbye H, Straand J.

Eur J Gen Pract. 2013 Jun;19(2):106-10. doi: 10.3109/13814788.2013.766713. Epub 2013 Apr 5.


Variation in family physicians' recording of auscultation abnormalities in patients with acute cough is not explained by case mix. A study from 12 European networks.

Francis NA, Melbye H, Kelly MJ, Cals JW, Hopstaken RM, Coenen S, Butler CC.

Eur J Gen Pract. 2013 Jun;19(2):77-84. doi: 10.3109/13814788.2012.733690. Epub 2013 Apr 2.


Primary care clinicians' perceptions of antibiotic resistance: a multi-country qualitative interview study.

Wood F, Phillips C, Brookes-Howell L, Hood K, Verheij T, Coenen S, Little P, Melbye H, Godycki-Cwirko M, Jakobsen K, Worby P, Goossens H, Butler CC.

J Antimicrob Chemother. 2013 Jan;68(1):237-43. doi: 10.1093/jac/dks338. Epub 2012 Sep 4.


Understanding variation in primary medical care: a nine-country qualitative study of clinicians' accounts of the non-clinical factors that shape antibiotic prescribing decisions for lower respiratory tract infection.

Brookes-Howell L, Hood K, Cooper L, Little P, Verheij T, Coenen S, Godycki-Cwirko M, Melbye H, Borras-Santos A, Worby P, Jakobsen K, Goossens H, Butler CC.

BMJ Open. 2012 Aug 22;2(4). pii: e000796. doi: 10.1136/bmjopen-2011-000796. Print 2012.


Hospitalisations due to exacerbation of asthma and COPD.

Melbye H, Moe PC, Arstad F.

Tidsskr Nor Laegeforen. 2012 Aug 7;132(14):1607-9. English, Norwegian.


Predictors of oxygen saturation ≤95% in a cross-sectional population based survey.

Vold ML, Aasebø U, Hjalmarsen A, Melbye H.

Respir Med. 2012 Nov;106(11):1551-8. doi: 10.1016/j.rmed.2012.06.016. Epub 2012 Jul 13.

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