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Items: 22


Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood.

Kononoff J, Melas PA, Kallupi M, de Guglielmo G, Kimbrough A, Scherma M, Fadda P, Kandel DB, Kandel ER, George O.

Sci Rep. 2018 Sep 17;8(1):13893. doi: 10.1038/s41598-018-31921-5.


The Class II Histone Deacetylase Hypothesis of Addiction.

Griffin EA Jr, Melas PA, Kandel DB, Kandel ER.

Biol Psychiatry. 2018 Aug 1;84(3):165-166. doi: 10.1016/j.biopsych.2018.06.006. Epub 2018 Jun 22. No abstract available.


NR3C1 hypermethylation in depressed and bullied adolescents.

Efstathopoulos P, Andersson F, Melas PA, Yang LL, Villaescusa JC, Rȕegg J, Ekström TJ, Forsell Y, Galanti MR, Lavebratt C.

Transl Psychiatry. 2018 Jun 19;8(1):121. doi: 10.1038/s41398-018-0169-8.


Cannabinoid Modulation of Eukaryotic Initiation Factors (eIF2α and eIF2B1) and Behavioral Cross-Sensitization to Cocaine in Adolescent Rats.

Melas PA, Qvist JS, Deidda M, Upreti C, Wei YB, Sanna F, Fratta W, Scherma M, Fadda P, Kandel DB, Kandel ER.

Cell Rep. 2018 Mar 13;22(11):2909-2923. doi: 10.1016/j.celrep.2018.02.065.


Neuropeptide Y, stressful life events and personality trait conscientiousness: Preliminary associations from a Swedish longitudinal study.

Melas PA, Guban P, Rahman MS, Lavebratt C, Forsell Y.

Psychiatry Res. 2018 May;263:48-53. doi: 10.1016/j.psychres.2018.02.041. Epub 2018 Feb 21.


Prior alcohol use enhances vulnerability to compulsive cocaine self-administration by promoting degradation of HDAC4 and HDAC5.

Griffin EA Jr, Melas PA, Zhou R, Li Y, Mercado P, Kempadoo KA, Stephenson S, Colnaghi L, Taylor K, Hu MC, Kandel ER, Kandel DB.

Sci Adv. 2017 Nov 1;3(11):e1701682. doi: 10.1126/sciadv.1701682. eCollection 2017 Nov.


The serotonin transporter promoter variant (5-HTTLPR) and childhood adversity are associated with the personality trait openness to experience.

Rahman MS, Guban P, Wang M, Melas PA, Forsell Y, Lavebratt C.

Psychiatry Res. 2017 Nov;257:322-326. doi: 10.1016/j.psychres.2017.07.071. Epub 2017 Jul 31.


MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro.

Wei YB, Melas PA, Villaescusa JC, Liu JJ, Xu N, Christiansen SH, Elbrønd-Bek H, Woldbye DP, Wegener G, Mathé AA, Lavebratt C.

Int J Neuropsychopharmacol. 2016 Dec 30;19(12). pii: pyw069. doi: 10.1093/ijnp/pyw069. Print 2016 Dec.


Mood Stabilizers and the Influence on Global Leukocyte DNA Methylation in Bipolar Disorder.

Backlund L, Wei YB, Martinsson L, Melas PA, Liu JJ, Mu N, Östenson CG, Ekström TJ, Schalling M, Lavebratt C.

Mol Neuropsychiatry. 2015 Jul;1(2):76-81. doi: 10.1159/000430867. Epub 2015 Jun 4.


Hypomethylation of MAOA's first exon region in depression: a replication study.

Melas PA, Forsell Y.

Psychiatry Res. 2015 Mar 30;226(1):389-91. doi: 10.1016/j.psychres.2015.01.003. Epub 2015 Jan 13.


Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene.

Wei Y, Melas PA, Wegener G, Mathé AA, Lavebratt C.

Int J Neuropsychopharmacol. 2014 Oct 31;18(2). pii: pyu032. doi: 10.1093/ijnp/pyu032. Erratum in: Int J Neuropsychopharmacol. 2015 Apr;18(6). pii: pyv026. doi: 10.1093/ijnp/pyv026.


Mental health literacy about depression and schizophrenia among adolescents in Sweden.

Melas PA, Tartani E, Forsner T, Edhborg M, Forsell Y.

Eur Psychiatry. 2013 Sep;28(7):404-11. doi: 10.1016/j.eurpsy.2013.02.002. Epub 2013 Jun 10.


Long-term lithium treatment in bipolar disorder is associated with longer leukocyte telomeres.

Martinsson L, Wei Y, Xu D, Melas PA, Mathé AA, Schalling M, Lavebratt C, Backlund L.

Transl Psychiatry. 2013 May 21;3:e261. doi: 10.1038/tp.2013.37.


Allele-specific programming of Npy and epigenetic effects of physical activity in a genetic model of depression.

Melas PA, Lennartsson A, Vakifahmetoglu-Norberg H, Wei Y, Åberg E, Werme M, Rogdaki M, Mannervik M, Wegener G, Brené S, Mathé AA, Lavebratt C.

Transl Psychiatry. 2013 May 7;3:e255. doi: 10.1038/tp.2013.31.


Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities.

Melas PA, Wei Y, Wong CC, Sjöholm LK, Åberg E, Mill J, Schalling M, Forsell Y, Lavebratt C.

Int J Neuropsychopharmacol. 2013 Aug;16(7):1513-28. doi: 10.1017/S1461145713000102. Epub 2013 Mar 1.


Epigenetic aberrations in leukocytes of patients with schizophrenia: association of global DNA methylation with antipsychotic drug treatment and disease onset.

Melas PA, Rogdaki M, Ösby U, Schalling M, Lavebratt C, Ekström TJ.

FASEB J. 2012 Jun;26(6):2712-8. doi: 10.1096/fj.11-202069. Epub 2012 Mar 16.


Neuropeptide Y: identification of a novel rat mRNA splice-variant that is downregulated in the hippocampus and the prefrontal cortex of a depression-like model.

Melas PA, Mannervik M, Mathé AA, Lavebratt C.

Peptides. 2012 May;35(1):49-55. doi: 10.1016/j.peptides.2012.02.020. Epub 2012 Mar 3.


Information related to prenatal genetic counseling: interpretation by adolescents, effects on risk perception and ethical implications.

Melas PA, Georgsson Öhman S, Juth N, Bui TH.

J Genet Couns. 2012 Aug;21(4):536-46. doi: 10.1007/s10897-011-9418-1. Epub 2011 Oct 25.


Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression.

Melas PA, Rogdaki M, Lennartsson A, Björk K, Qi H, Witasp A, Werme M, Wegener G, Mathé AA, Svenningsson P, Lavebratt C.

Int J Neuropsychopharmacol. 2012 Jun;15(5):669-79. doi: 10.1017/S1461145711000940. Epub 2011 Jun 20.


Selected summaries from the XVII World Congress of Psychiatric Genetics, San Diego, California, USA, 4-8 November 2009.

Amstadter AB, Balachandar V, Bergen SE, Ceulemans S, Christensen JH, Cole J, Dagdan E, De Luca V, Ducci F, Tee SF, Hartz S, Keers R, Medland S, Melas PA, Mühleisen TW, Ozomaro U, Pidsley R, Scott AP, Sha L, Talati A, Teltsh O, Videtic A, Wang K, Wong CC, Delisi LE.

Psychiatr Genet. 2010 Oct;20(5):229-68. doi: 10.1097/YPG.0b013e32833d17c3. Erratum in: Psychiatr Genet. 2011 Feb;21(1):55. Dagdan, Elif [added].


Examining the public refusal to consent to DNA biobanking: empirical data from a Swedish population-based study.

Melas PA, Sjöholm LK, Forsner T, Edhborg M, Juth N, Forsell Y, Lavebratt C.

J Med Ethics. 2010 Feb;36(2):93-8. doi: 10.1136/jme.2009.032367.


PreproNPY Pro7 protects against depression despite exposure to environmental risk factors.

Sjöholm LK, Melas PA, Forsell Y, Lavebratt C.

J Affect Disord. 2009 Nov;118(1-3):124-30. doi: 10.1016/j.jad.2009.02.009. Epub 2009 Mar 4.


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