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Items: 15


Individual Ion Mass Spectrometry Enhances the Sensitivity and Sequence Coverage of Top-Down Mass Spectrometry.

Kafader JO, Durbin KR, Melani RD, Des Soye BJ, Schachner LF, Senko MW, Compton PD, Kelleher NL.

J Proteome Res. 2020 Feb 11. doi: 10.1021/acs.jproteome.9b00797. [Epub ahead of print]


Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions.

Kafader JO, Melani RD, Schachner LF, Ives AN, Patrie SM, Kelleher NL, Compton PD.

J Am Soc Mass Spectrom. 2020 Feb 4. doi: 10.1021/jasms.9b00040. [Epub ahead of print]


Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics.

Fornelli L, Srzentić K, Toby TK, Doubleday PF, Huguet R, Mullen C, Melani RD, Dos Santos Seckler H, DeHart CJ, Weisbrod CR, Durbin KR, Greer JB, Early BP, Fellers RT, Zabrouskov V, Thomas PM, Compton PD, Kelleher NL.

Mol Cell Proteomics. 2020 Feb;19(2):405-420. doi: 10.1074/mcp.TIR119.001638. Epub 2019 Dec 30.


Direct measurement of light and heavy antibody chains using ion mobility and middle-down mass spectrometry.

Melani RD, Srzentić K, Gerbasi VR, McGee JP, Huguet R, Fornelli L, Kelleher NL.

MAbs. 2019 Nov-Dec;11(8):1351-1357. doi: 10.1080/19420862.2019.1668226. Epub 2019 Oct 13.


STORI Plots Enable Accurate Tracking of Individual Ion Signals.

Kafader JO, Beu SC, Early BP, Melani RD, Durbin KR, Zabrouskov V, Makarov AA, Maze JT, Shinholt DL, Yip PF, Kelleher NL, Compton PD, Senko MW.

J Am Soc Mass Spectrom. 2019 Nov;30(11):2200-2203. doi: 10.1007/s13361-019-02309-0. Epub 2019 Sep 11.


Understanding xylose isomerase from Burkholderia cenocepacia: insights into structure and functionality for ethanol production.

Vieira IPV, Cordeiro GT, Gomes DEB, Melani RD, Vilela LF, Domont GB, Mesquita RD, Eleutherio ECA, Neves BC.

AMB Express. 2019 May 24;9(1):73. doi: 10.1186/s13568-019-0795-4.


Standard Proteoforms and Their Complexes for Native Mass Spectrometry.

Schachner LF, Ives AN, McGee JP, Melani RD, Kafader JO, Compton PD, Patrie SM, Kelleher NL.

J Am Soc Mass Spectrom. 2019 Jul;30(7):1190-1198. doi: 10.1007/s13361-019-02191-w. Epub 2019 Apr 8.


Measurement of Individual Ions Sharply Increases the Resolution of Orbitrap Mass Spectra of Proteins.

Kafader JO, Melani RD, Senko MW, Makarov AA, Kelleher NL, Compton PD.

Anal Chem. 2019 Feb 19;91(4):2776-2783. doi: 10.1021/acs.analchem.8b04519. Epub 2019 Jan 29.


Top-down characterization of endogenous protein complexes with native proteomics.

Skinner OS, Haverland NA, Fornelli L, Melani RD, Do Vale LHF, Seckler HS, Doubleday PF, Schachner LF, Srzentić K, Kelleher NL, Compton PD.

Nat Chem Biol. 2018 Jan;14(1):36-41. doi: 10.1038/nchembio.2515. Epub 2017 Nov 13.


It is time for top-down venomics.

Melani RD, Nogueira FCS, Domont GB.

J Venom Anim Toxins Incl Trop Dis. 2017 Oct 18;23:44. doi: 10.1186/s40409-017-0135-6. eCollection 2017. Review.


Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics.

Melani RD, Skinner OS, Fornelli L, Domont GB, Compton PD, Kelleher NL.

Mol Cell Proteomics. 2016 Jul;15(7):2423-34. doi: 10.1074/mcp.M115.056523. Epub 2016 May 13.


CN-GELFrEE - Clear Native Gel-eluted Liquid Fraction Entrapment Electrophoresis.

Melani RD, Seckler HS, Skinner OS, Do Vale LH, Catherman AD, Havugimana PC, Valle de Sousa M, Domont GB, Kelleher NL, Compton PD.

J Vis Exp. 2016 Feb 29;(108):53597. doi: 10.3791/53597.


An informatic framework for decoding protein complexes by top-down mass spectrometry.

Skinner OS, Havugimana PC, Haverland NA, Fornelli L, Early BP, Greer JB, Fellers RT, Durbin KR, Do Vale LH, Melani RD, Seckler HS, Nelp MT, Belov ME, Horning SR, Makarov AA, LeDuc RD, Bandarian V, Compton PD, Kelleher NL.

Nat Methods. 2016 Mar;13(3):237-40. doi: 10.1038/nmeth.3731. Epub 2016 Jan 18.


Exploring the proteomic landscape of a gastric cancer biopsy with the shotgun imaging analyzer.

Aquino PF, Lima DB, de Saldanha da Gama Fischer J, Melani RD, Nogueira FC, Chalub SR, Soares ER, Barbosa VC, Domont GB, Carvalho PC.

J Proteome Res. 2014 Jan 3;13(1):314-20. doi: 10.1021/pr400919k. Epub 2013 Nov 27.


Amarelinha do Amapá: a carotenoid-rich cassava cultivar.

Nassar NM, Fernandes PC, Melani RD, Pires OR Jr.

Genet Mol Res. 2009 Aug 25;8(3):1051-5. doi: 10.4238/vol8-3gmr625.

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