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Items: 9


GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism.

Young SG, Fong LG, Beigneux AP, Allan CM, He C, Jiang H, Nakajima K, Meiyappan M, Birrane G, Ploug M.

Cell Metab. 2019 Jul 2;30(1):51-65. doi: 10.1016/j.cmet.2019.05.023. Review.


Inter-assay variability influences migalastat amenability assessments among Fabry disease variants.

Oommen S, Zhou Y, Meiyappan M, Gurevich A, Qiu Y.

Mol Genet Metab. 2019 May;127(1):74-85. doi: 10.1016/j.ymgme.2019.04.005. Epub 2019 Apr 15.


Lipoprotein lipase is active as a monomer.

Beigneux AP, Allan CM, Sandoval NP, Cho GW, Heizer PJ, Jung RS, Stanhope KL, Havel PJ, Birrane G, Meiyappan M, Gill JE 4th, Murakami M, Miyashita K, Nakajima K, Ploug M, Fong LG, Young SG.

Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6319-6328. doi: 10.1073/pnas.1900983116. Epub 2019 Mar 8.


Structural characterization of the α-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B.

Birrane G, Dassier AL, Romashko A, Lundberg D, Holmes K, Cottle T, Norton AW, Zhang B, Concino MF, Meiyappan M.

J Struct Biol. 2019 Mar 1;205(3):65-71. doi: 10.1016/j.jsb.2019.02.005. Epub 2019 Feb 23.


Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis.

Birrane G, Beigneux AP, Dwyer B, Strack-Logue B, Kristensen KK, Francone OL, Fong LG, Mertens HDT, Pan CQ, Ploug M, Young SG, Meiyappan M.

Proc Natl Acad Sci U S A. 2019 Jan 29;116(5):1723-1732. doi: 10.1073/pnas.1817984116. Epub 2018 Dec 17.


Protein Engineering on Human Recombinant Follistatin: Enhancing Pharmacokinetic Characteristics for Therapeutic Application.

Shen C, Iskenderian A, Lundberg D, He T, Palmieri K, Crooker R, Deng Q, Traylor M, Gu S, Rong H, Ehmann D, Pescatore B, Strack-Logue B, Romashko A, Baviello G, Gill J, Zhang B, Meiyappan M, Pan C, Norton AW.

J Pharmacol Exp Ther. 2018 Aug;366(2):291-302. doi: 10.1124/jpet.118.248195. Epub 2018 May 11.


Structural basis for polyproline recognition by the FE65 WW domain.

Meiyappan M, Birrane G, Ladias JAA.

J Mol Biol. 2007 Sep 28;372(4):970-980. doi: 10.1016/j.jmb.2007.06.064. Epub 2007 Jun 29.


Transglutaminase 5 is regulated by guanine-adenine nucleotides.

Candi E, Paradisi A, Terrinoni A, Pietroni V, Oddi S, Cadot B, Jogini V, Meiyappan M, Clardy J, Finazzi-Agro A, Melino G.

Biochem J. 2004 Jul 1;381(Pt 1):313-9.


Crystal structure of NC1 domains. Structural basis for type IV collagen assembly in basement membranes.

Sundaramoorthy M, Meiyappan M, Todd P, Hudson BG.

J Biol Chem. 2002 Aug 23;277(34):31142-53. Epub 2002 Apr 22.

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