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Extracellular RNA released due to shear stress controls natural bypass growth by mediating mechanotransduction.

Lasch M, Kleinert EC, Meister S, Kumaraswami K, Buchheim JI, Grantzow T, Lautz T, Salpisti S, Fischer S, Troidl K, Fleming I, Randi AM, Sperandio M, Preissner KT, Deindl E.

Blood. 2019 Sep 9. pii: blood.2019001392. doi: 10.1182/blood.2019001392. [Epub ahead of print]


Tracing charge transfer in argon dimers by XUV-pump IR-probe experiments at FLASH.

Schmid G, Schnorr K, Augustin S, Meister S, Lindenblatt H, Trost F, Liu Y, Miteva T, Gisselbrecht M, Düsterer S, Redlin H, Treusch R, Gokhberg K, Kuleff AI, Cederbaum LS, Schröter CD, Pfeifer T, Moshammer R.

J Chem Phys. 2019 Aug 28;151(8):084314. doi: 10.1063/1.5116234.


Substance Use and Prevention Programs in Berlin's Party Scene: Results of the SuPrA-Study.

Betzler F, Ernst F, Helbig J, Viohl L, Roediger L, Meister S, Romanczuk-Seiferth N, Heinz A, Ströhle A, Köhler S.

Eur Addict Res. 2019 Jul 12:1-10. doi: 10.1159/000501310. [Epub ahead of print]


Incidence and Prevalence of Borrelia burgdorferi Antibodies in Male Professional Football Players.

Breitbart P, Meister S, Meyer T, Gärtner BC.

Clin J Sport Med. 2019 May 30. doi: 10.1097/JSM.0000000000000758. [Epub ahead of print]


Substituted Aminoacetamides as Novel Leads for Malaria Treatment.

Norcross NR, Wilson C, Baragaña B, Hallyburton I, Osuna-Cabello M, Norval S, Riley J, Fletcher D, Sinden R, Delves M, Ruecker A, Duffy S, Meister S, Antonova-Koch Y, Crespo B, de Cózar C, Sanz LM, Gamo FJ, Avery VM, Frearson JA, Gray DW, Fairlamb AH, Winzeler EA, Waterson D, Campbell SF, Willis PA, Read KD, Gilbert IH.

ChemMedChem. 2019 Jul 17;14(14):1329-1335. doi: 10.1002/cmdc.201900329. Epub 2019 Jul 3.


Reaction microscope endstation at FLASH2.

Schmid G, Schnorr K, Augustin S, Meister S, Lindenblatt H, Trost F, Liu Y, Braune M, Treusch R, Schröter CD, Pfeifer T, Moshammer R.

J Synchrotron Radiat. 2019 May 1;26(Pt 3):854-867. doi: 10.1107/S1600577519002236. Epub 2019 Apr 9.


Cyclization-blocked proguanil as a strategy to improve the antimalarial activity of atovaquone.

Skinner-Adams TS, Fisher GM, Riches AG, Hutt OE, Jarvis KE, Wilson T, von Itzstein M, Chopra P, Antonova-Koch Y, Meister S, Winzeler EA, Clarke M, Fidock DA, Burrows JN, Ryan JH, Andrews KT.

Commun Biol. 2019 May 3;2:166. doi: 10.1038/s42003-019-0397-3. eCollection 2019.


[Digital Nephrology].

Becker S, Budde K, Tillmann FP, Koisar K, Wamprecht L, Müschenich M, Meister S, Roller R.

Dtsch Med Wochenschr. 2019 Apr;144(7):452-456. doi: 10.1055/a-0740-8662. Epub 2019 Mar 29. German.


Terahertz-Field-Induced Time Shifts in Atomic Photoemission.

Schmid G, Schnorr K, Augustin S, Meister S, Lindenblatt H, Trost F, Liu Y, Stojanovic N, Al-Shemmary A, Golz T, Treusch R, Gensch M, Kübel M, Foucar L, Rudenko A, Ullrich J, Schröter CD, Pfeifer T, Moshammer R.

Phys Rev Lett. 2019 Feb 22;122(7):073001. doi: 10.1103/PhysRevLett.122.073001.


A genetic variant associated with multiple sclerosis inversely affects the expression of CD58 and microRNA-548ac from the same gene.

Hecker M, Boxberger N, Illner N, Fitzner B, Schröder I, Winkelmann A, Dudesek A, Meister S, Koczan D, Lorenz P, Thiesen HJ, Zettl UK.

PLoS Genet. 2019 Feb 7;15(2):e1007961. doi: 10.1371/journal.pgen.1007961. eCollection 2019 Feb.


8-Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual-Stage Antiplasmodial Activity.

Leven M, Held J, Duffy S, Alves Avelar LA, Meister S, Delves M, Plouffe D, Kuna K, Tschan S, Avery VM, Winzeler EA, Mordmüller B, Kurz T.

ChemMedChem. 2019 Feb 19;14(4):501-511. doi: 10.1002/cmdc.201800691. Epub 2019 Jan 14.


Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.

Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, Chaumeau V, Conway AJ, McNamara CW, Ibanez M, Gagaring K, Serrano FN, Eribez K, Taggard CM, Cheung AL, Lincoln C, Ambachew B, Rouillier M, Siegel D, Nosten F, Kyle DE, Gamo FJ, Zhou Y, Llinás M, Fidock DA, Wirth DF, Burrows J, Campo B, Winzeler EA.

Science. 2018 Dec 7;362(6419). pii: eaat9446. doi: 10.1126/science.aat9446.


Directed evolution of the 3C protease from coxsackievirus using a novel fluorescence-assisted intracellular method.

Meister SW, Hendrikse NM, Löfblom J.

Biol Chem. 2019 Feb 25;400(3):405-415. doi: 10.1515/hsz-2018-0362.


Large scale in vivo micro-RNA loss of function screen identified miR-29a, miR-100 and miR-155 as modulators of radioresistance and tumor-stroma communication.

Fahim Golestaneh A, Lecker LSM, Schlegel J, Nowrouzi A, Schwager C, Meister S, Weichert W, Debus J, Abdollahi A.

Int J Cancer. 2019 Jun 1;144(11):2774-2781. doi: 10.1002/ijc.32019. Epub 2019 Jan 4.


One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites.

Diedrich D, Stenzel K, Hesping E, Antonova-Koch Y, Gebru T, Duffy S, Fisher G, Schöler A, Meister S, Kurz T, Avery VM, Winzeler EA, Held J, Andrews KT, Hansen FK.

Eur J Med Chem. 2018 Oct 5;158:801-813. doi: 10.1016/j.ejmech.2018.09.018. Epub 2018 Sep 7.


[Strategies for digitalizing the hospital of the future].

Deiters W, Burmann A, Meister S.

Urologe A. 2018 Sep;57(9):1031-1039. doi: 10.1007/s00120-018-0731-2. Review. German.


Smart Medical Information Technology for Healthcare (SMITH).

Winter A, Stäubert S, Ammon D, Aiche S, Beyan O, Bischoff V, Daumke P, Decker S, Funkat G, Gewehr JE, de Greiff A, Haferkamp S, Hahn U, Henkel A, Kirsten T, Klöss T, Lippert J, Löbe M, Lowitsch V, Maassen O, Maschmann J, Meister S, Mikolajczyk R, Nüchter M, Pletz MW, Rahm E, Riedel M, Saleh K, Schuppert A, Smers S, Stollenwerk A, Uhlig S, Wendt T, Zenker S, Fleig W, Marx G, Scherag A, Löffler M.

Methods Inf Med. 2018 Jul;57(S 01):e92-e105. doi: 10.3414/ME18-02-0004. Epub 2018 Jul 17.


Developing Plasmodium vivax Resources for Liver Stage Study in the Peruvian Amazon Region.

Orjuela-Sanchez P, Villa ZH, Moreno M, Tong-Rios C, Meister S, LaMonte GM, Campo B, Vinetz JM, Winzeler EA.

ACS Infect Dis. 2018 Apr 13;4(4):531-540. doi: 10.1021/acsinfecdis.7b00198. Epub 2018 Mar 15.


Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains.

Meister S, Verbyla ME, Klinger M, Kohn T.

Environ Sci Technol. 2018 Mar 20;52(6):3696-3705. doi: 10.1021/acs.est.8b00851. Epub 2018 Mar 2.


Overexpression of Receptor Tyrosine Kinase EphB4 Triggers Tumor Growth and Hypoxia in A375 Melanoma Xenografts: Insights from Multitracer Small Animal Imaging Experiments.

Neuber C, Belter B, Meister S, Hofheinz F, Bergmann R, Pietzsch HJ, Pietzsch J.

Molecules. 2018 Feb 17;23(2). pii: E444. doi: 10.3390/molecules23020444.


Positive effect of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) on homogeneous photocatalytic reduction of CO2.

Pschenitza M, Meister S, Rieger B.

Chem Commun (Camb). 2018 Mar 29;54(27):3323-3326. doi: 10.1039/c7cc08927a.


Transcriptome profiling of peripheral blood immune cell populations in multiple sclerosis patients before and during treatment with a sphingosine-1-phosphate receptor modulator.

Angerer IC, Hecker M, Koczan D, Roch L, Friess J, Rüge A, Fitzner B, Boxberger N, Schröder I, Flechtner K, Thiesen HJ, Winkelmann A, Meister S, Zettl UK.

CNS Neurosci Ther. 2018 Mar;24(3):193-201. doi: 10.1111/cns.12793. Epub 2018 Jan 3.


An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment.

Huebner D, Rieger C, Bergmann R, Ullrich M, Meister S, Toma M, Wiedemuth R, Temme A, Novotny V, Wirth MP, Bachmann M, Pietzsch J, Fuessel S.

BMC Cancer. 2017 Nov 23;17(1):790. doi: 10.1186/s12885-017-3778-3.


Effect of E-Bike Versus Bike Commuting on Cardiorespiratory Fitness in Overweight Adults: A 4-Week Randomized Pilot Study.

Höchsmann C, Meister S, Gehrig D, Gordon E, Li Y, Nussbaumer M, Rossmeissl A, Schäfer J, Hanssen H, Schmidt-Trucksäss A.

Clin J Sport Med. 2018 May;28(3):255-265. doi: 10.1097/JSM.0000000000000438.


Design and Synthesis of Terephthalic Acid-Based Histone Deacetylase Inhibitors with Dual-Stage Anti-Plasmodium Activity.

Stenzel K, Chua MJ, Duffy S, Antonova-Koch Y, Meister S, Hamacher A, Kassack MU, Winzeler E, Avery VM, Kurz T, Andrews KT, Hansen FK.

ChemMedChem. 2017 Oct 9;12(19):1627-1636. doi: 10.1002/cmdc.201700360. Epub 2017 Sep 13.


3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.

Leven M, Knaab TC, Held J, Duffy S, Meister S, Fischli C, Meitzner D, Lehmann U, Lungerich B, Kuna K, Stahlke P, Delves MJ, Buchholz M, Winzeler EA, Avery VM, Mordmüller B, Wittlin S, Kurz T.

J Med Chem. 2017 Jul 27;60(14):6036-6044. doi: 10.1021/acs.jmedchem.7b00140. Epub 2017 Jul 17.


Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.

Magistrado PA, Corey VC, Lukens AK, LaMonte G, Sasaki E, Meister S, Wree M, Winzeler E, Wirth DF.

ACS Infect Dis. 2016 Nov 11;2(11):816-826. Epub 2016 Apr 7.


Flow-cytometric screening of aggregation-inhibitors using a fluorescence-assisted intracellular method.

Lindberg H, Sandersjöö L, Meister SW, Uhlén M, Löfblom J, Ståhl S.

Biotechnol J. 2017 Jan;12(1). doi: 10.1002/biot.201600364. Epub 2016 Dec 1.


Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

El-Battrawy I, Lang S, Zhao Z, Akin I, Yücel G, Meister S, Patocskai B, Behnes M, Rudic B, Tülümen E, Liebe V, Tiburcy M, Dworacek J, Zimmermann WH, Utikal J, Wieland T, Borggrefe M, Zhou XB.

PLoS One. 2016 Nov 9;11(11):e0166143. doi: 10.1371/journal.pone.0166143. eCollection 2016.


[Diagnostic Workup and Treatment of Antibody-Related Encephalomyelitis].

Patejdl R, Winkelmann A, Ehler J, Zettl H, Meister S, Zettl UK.

Fortschr Neurol Psychiatr. 2016 Oct;84(S 02):S88-S91. Epub 2016 Nov 2. Review. German.


Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles.

Williamson AE, Ylioja PM, Robertson MN, Antonova-Koch Y, Avery V, Baell JB, Batchu H, Batra S, Burrows JN, Bhattacharyya S, Calderon F, Charman SA, Clark J, Crespo B, Dean M, Debbert SL, Delves M, Dennis AS, Deroose F, Duffy S, Fletcher S, Giaever G, Hallyburton I, Gamo FJ, Gebbia M, Guy RK, Hungerford Z, Kirk K, Lafuente-Monasterio MJ, Lee A, Meister S, Nislow C, Overington JP, Papadatos G, Patiny L, Pham J, Ralph SA, Ruecker A, Ryan E, Southan C, Srivastava K, Swain C, Tarnowski MJ, Thomson P, Turner P, Wallace IM, Wells TN, White K, White L, Willis P, Winzeler EA, Wittlin S, Todd MH.

ACS Cent Sci. 2016 Oct 26;2(10):687-701. Epub 2016 Sep 14.


Identification of a Potential Antimalarial Drug Candidate from a Series of 2-Aminopyrazines by Optimization of Aqueous Solubility and Potency across the Parasite Life Cycle.

Le Manach C, Nchinda AT, Paquet T, Gonzàlez Cabrera D, Younis Y, Han Z, Bashyam S, Zabiulla M, Taylor D, Lawrence N, White KL, Charman SA, Waterson D, Witty MJ, Wittlin S, Botha ME, Nondaba SH, Reader J, Birkholtz LM, Jiménez-Díaz MB, Martínez MS, Ferrer S, Angulo-Barturen I, Meister S, Antonova-Koch Y, Winzeler EA, Street LJ, Chibale K.

J Med Chem. 2016 Nov 10;59(21):9890-9905. Epub 2016 Oct 26.


High-Resolution Expression Profiling of Peripheral Blood CD8+ Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution.

Roch L, Hecker M, Friess J, Angerer IC, Koczan D, Fitzner B, Schröder I, Flechtner K, Thiesen HJ, Meister S, Winkelmann A, Zettl UK.

Mol Neurobiol. 2017 Sep;54(7):5511-5525. doi: 10.1007/s12035-016-0075-0. Epub 2016 Sep 8.


Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.

Baragaña B, Norcross NR, Wilson C, Porzelle A, Hallyburton I, Grimaldi R, Osuna-Cabello M, Norval S, Riley J, Stojanovski L, Simeons FR, Wyatt PG, Delves MJ, Meister S, Duffy S, Avery VM, Winzeler EA, Sinden RE, Wittlin S, Frearson JA, Gray DW, Fairlamb AH, Waterson D, Campbell SF, Willis P, Read KD, Gilbert IH.

J Med Chem. 2016 Nov 10;59(21):9672-9685. Epub 2016 Sep 10.


A mobile application improves therapy-adherence rates in elderly patients undergoing rehabilitation: A crossover design study comparing documentation via iPad with paper-based control.

Mertens A, Brandl C, Miron-Shatz T, Schlick C, Neumann T, Kribben A, Meister S, Diamantidis CJ, Albrecht UV, Horn P, Becker S.

Medicine (Baltimore). 2016 Sep;95(36):e4446. doi: 10.1097/MD.0000000000004446.


Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, Baker S, Ben Mamoun C, Bhatia S, Bickle Q, Bounaadja L, Bowling T, Bosch J, Boucher LE, Boyom FF, Brea J, Brennan M, Burton A, Caffrey CR, Camarda G, Carrasquilla M, Carter D, Belen Cassera M, Chih-Chien Cheng K, Chindaudomsate W, Chubb A, Colon BL, Colón-López DD, Corbett Y, Crowther GJ, Cowan N, D'Alessandro S, Le Dang N, Delves M, DeRisi JL, Du AY, Duffy S, Abd El-Salam El-Sayed S, Ferdig MT, Fernández Robledo JA, Fidock DA, Florent I, Fokou PV, Galstian A, Gamo FJ, Gokool S, Gold B, Golub T, Goldgof GM, Guha R, Guiguemde WA, Gural N, Guy RK, Hansen MA, Hanson KK, Hemphill A, Hooft van Huijsduijnen R, Horii T, Horrocks P, Hughes TB, Huston C, Igarashi I, Ingram-Sieber K, Itoe MA, Jadhav A, Naranuntarat Jensen A, Jensen LT, Jiang RH, Kaiser A, Keiser J, Ketas T, Kicka S, Kim S, Kirk K, Kumar VP, Kyle DE, Lafuente MJ, Landfear S, Lee N, Lee S, Lehane AM, Li F, Little D, Liu L, Llinás M, Loza MI, Lubar A, Lucantoni L, Lucet I, Maes L, Mancama D, Mansour NR, March S, McGowan S, Medina Vera I, Meister S, Mercer L, Mestres J, Mfopa AN, Misra RN, Moon S, Moore JP, Morais Rodrigues da Costa F, Müller J, Muriana A, Nakazawa Hewitt S, Nare B, Nathan C, Narraidoo N, Nawaratna S, Ojo KK, Ortiz D, Panic G, Papadatos G, Parapini S, Patra K, Pham N, Prats S, Plouffe DM, Poulsen SA, Pradhan A, Quevedo C, Quinn RJ, Rice CA, Abdo Rizk M, Ruecker A, St Onge R, Salgado Ferreira R, Samra J, Robinett NG, Schlecht U, Schmitt M, Silva Villela F, Silvestrini F, Sinden R, Smith DA, Soldati T, Spitzmüller A, Stamm SM, Sullivan DJ, Sullivan W, Suresh S, Suzuki BM, Suzuki Y, Swamidass SJ, Taramelli D, Tchokouaha LR, Theron A, Thomas D, Tonissen KF, Townson S, Tripathi AK, Trofimov V, Udenze KO, Ullah I, Vallieres C, Vigil E, Vinetz JM, Voong Vinh P, Vu H, Watanabe NA, Weatherby K, White PM, Wilks AF, Winzeler EA, Wojcik E, Wree M, Wu W, Yokoyama N, Zollo PH, Abla N, Blasco B, Burrows J, Laleu B, Leroy D, Spangenberg T, Wells T, Willis PA.

PLoS Pathog. 2016 Jul 28;12(7):e1005763. doi: 10.1371/journal.ppat.1005763. eCollection 2016 Jul.


Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials.

Norcross NR, Baragaña B, Wilson C, Hallyburton I, Osuna-Cabello M, Norval S, Riley J, Stojanovski L, Simeons FR, Porzelle A, Grimaldi R, Wittlin S, Duffy S, Avery VM, Meister S, Sanz L, Jiménez-Díaz B, Angulo-Barturen I, Ferrer S, Martínez MS, Gamo FJ, Frearson JA, Gray DW, Fairlamb AH, Winzeler EA, Waterson D, Campbell SF, Willis P, Read KD, Gilbert IH.

J Med Chem. 2016 Jul 14;59(13):6101-20. doi: 10.1021/acs.jmedchem.6b00028. Epub 2016 Jun 17.


A broad analysis of resistance development in the malaria parasite.

Corey VC, Lukens AK, Istvan ES, Lee MCS, Franco V, Magistrado P, Coburn-Flynn O, Sakata-Kato T, Fuchs O, Gnädig NF, Goldgof G, Linares M, Gomez-Lorenzo MG, De Cózar C, Lafuente-Monasterio MJ, Prats S, Meister S, Tanaseichuk O, Wree M, Zhou Y, Willis PA, Gamo FJ, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Nat Commun. 2016 Jun 15;7:11901. doi: 10.1038/ncomms11901.


Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A, Martínez MS, Bolscher JM, Woodland A, Luksch T, Norval S, Zuccotto F, Thomas J, Simeons F, Stojanovski L, Osuna-Cabello M, Brock PM, Churcher TS, Sala KA, Zakutansky SE, Jiménez-Díaz MB, Sanz LM, Riley J, Basak R, Campbell M, Avery VM, Sauerwein RW, Dechering KJ, Noviyanti R, Campo B, Frearson JA, Angulo-Barturen I, Ferrer-Bazaga S, Gamo FJ, Wyatt PG, Leroy D, Siegl P, Delves MJ, Kyle DE, Wittlin S, Marfurt J, Price RN, Sinden RE, Winzeler EA, Charman SA, Bebrevska L, Gray DW, Campbell S, Fairlamb AH, Willis PA, Rayner JC, Fidock DA, Read KD, Gilbert IH.

Nature. 2016 Sep 1;537(7618):122. doi: 10.1038/nature18280. Epub 2016 May 25. No abstract available.


High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria.

Swann J, Corey V, Scherer CA, Kato N, Comer E, Maetani M, Antonova-Koch Y, Reimer C, Gagaring K, Ibanez M, Plouffe D, Zeeman AM, Kocken CH, McNamara CW, Schreiber SL, Campo B, Winzeler EA, Meister S.

ACS Infect Dis. 2016 Apr 8;2(4):281-293. Epub 2016 Feb 10.


Synthesis of (+)-7,20-Diisocyanoadociane and Liver-Stage Antiplasmodial Activity of the Isocyanoterpene Class.

Lu HH, Pronin SV, Antonova-Koch Y, Meister S, Winzeler EA, Shenvi RA.

J Am Chem Soc. 2016 Jun 15;138(23):7268-71. doi: 10.1021/jacs.6b03899. Epub 2016 May 31.


MTE1 Functions with MPH1 in Double-Strand Break Repair.

Yimit A, Kim T, Anand RP, Meister S, Ou J, Haber JE, Zhang Z, Brown GW.

Genetics. 2016 May;203(1):147-57. doi: 10.1534/genetics.115.185454. Epub 2016 Feb 26.


A Case Report of a Carbamazepine Overdose With Focus on Pharmacokinetic Aspects.

Mittag N, Meister S, Berg AM, Walther UI.

Pharmacopsychiatry. 2016 Mar;49(2):76-8. doi: 10.1055/s-0035-1569268. Epub 2016 Jan 21.


High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.

Plouffe DM, Wree M, Du AY, Meister S, Li F, Patra K, Lubar A, Okitsu SL, Flannery EL, Kato N, Tanaseichuk O, Comer E, Zhou B, Kuhen K, Zhou Y, Leroy D, Schreiber SL, Scherer CA, Vinetz J, Winzeler EA.

Cell Host Microbe. 2016 Jan 13;19(1):114-26. doi: 10.1016/j.chom.2015.12.001. Epub 2015 Dec 31.


Endothelial LRP1 transports amyloid-β(1-42) across the blood-brain barrier.

Storck SE, Meister S, Nahrath J, Meißner JN, Schubert N, Di Spiezio A, Baches S, Vandenbroucke RE, Bouter Y, Prikulis I, Korth C, Weggen S, Heimann A, Schwaninger M, Bayer TA, Pietrzik CU.

J Clin Invest. 2016 Jan;126(1):123-36. doi: 10.1172/JCI81108. Epub 2015 Nov 30.


A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.

Le Manach C, Paquet T, Brunschwig C, Njoroge M, Han Z, Gonzàlez Cabrera D, Bashyam S, Dhinakaran R, Taylor D, Reader J, Botha M, Churchyard A, Lauterbach S, Coetzer TL, Birkholtz LM, Meister S, Winzeler EA, Waterson D, Witty MJ, Wittlin S, Jiménez-Díaz MB, Santos Martínez M, Ferrer S, Angulo-Barturen I, Street LJ, Chibale K.

J Med Chem. 2015 Nov 12;58(21):8713-22. doi: 10.1021/acs.jmedchem.5b01605. Epub 2015 Nov 2.


Dose-response relationship between light exposure and cycling performance.

Knaier R, Meister S, Aeschbacher T, Gemperle D, Rossmeissl A, Cajochen C, Schmidt-Trucksäss A.

Scand J Med Sci Sports. 2016 Jul;26(7):794-801. doi: 10.1111/sms.12535. Epub 2015 Aug 14.


Training of verbal creativity modulates brain activity in regions associated with language- and memory-related demands.

Fink A, Benedek M, Koschutnig K, Pirker E, Berger E, Meister S, Neubauer AC, Papousek I, Weiss EM.

Hum Brain Mapp. 2015 Oct;36(10):4104-15. doi: 10.1002/hbm.22901. Epub 2015 Jul 14.


A novel multiple-stage antimalarial agent that inhibits protein synthesis.

Baragaña B, Hallyburton I, Lee MC, Norcross NR, Grimaldi R, Otto TD, Proto WR, Blagborough AM, Meister S, Wirjanata G, Ruecker A, Upton LM, Abraham TS, Almeida MJ, Pradhan A, Porzelle A, Luksch T, Martínez MS, Luksch T, Bolscher JM, Woodland A, Norval S, Zuccotto F, Thomas J, Simeons F, Stojanovski L, Osuna-Cabello M, Brock PM, Churcher TS, Sala KA, Zakutansky SE, Jiménez-Díaz MB, Sanz LM, Riley J, Basak R, Campbell M, Avery VM, Sauerwein RW, Dechering KJ, Noviyanti R, Campo B, Frearson JA, Angulo-Barturen I, Ferrer-Bazaga S, Gamo FJ, Wyatt PG, Leroy D, Siegl P, Delves MJ, Kyle DE, Wittlin S, Marfurt J, Price RN, Sinden RE, Winzeler EA, Charman SA, Bebrevska L, Gray DW, Campbell S, Fairlamb AH, Willis PA, Rayner JC, Fidock DA, Read KD, Gilbert IH.

Nature. 2015 Jun 18;522(7556):315-20. doi: 10.1038/nature14451. Erratum in: Nature. 2016 Sep 1;537(7618):122.


Expression of the ALS-causing variant hSOD1(G93A) leads to an impaired integrity and altered regulation of claudin-5 expression in an in vitro blood-spinal cord barrier model.

Meister S, Storck SE, Hameister E, Behl C, Weggen S, Clement AM, Pietrzik CU.

J Cereb Blood Flow Metab. 2015 Jul;35(7):1112-21. doi: 10.1038/jcbfm.2015.57. Epub 2015 Apr 8.

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