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Items: 1 to 50 of 343

1.

Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel.

Xu L, Chirasani VR, Carter JS, Pasek DA, Dokholyan NV, Yamaguchi N, Meissner G.

J Biol Chem. 2018 Oct 19. pii: jbc.RA118.004453. doi: 10.1074/jbc.RA118.004453. [Epub ahead of print]

2.

Optimization of fluorophores for chemical tagging and immunohistochemistry of Drosophila neurons.

Meissner GW, Grimm JB, Johnston RM, Sutcliffe B, Ng J, Jefferis GSXE, Cachero S, Lavis LD, Malkesman O.

PLoS One. 2018 Aug 15;13(8):e0200759. doi: 10.1371/journal.pone.0200759. eCollection 2018.

3.

Extrinsic and Intrinsic Help-Seeking Motivation in the Assessment of Cognitive Decline.

Haussmann R, Mayer-Pelinski R, Borchardt M, Beier F, Helling F, Buthut M, Meissner G, Lange J, Zweiniger A, Donix M.

Am J Alzheimers Dis Other Demen. 2018 Jun;33(4):215-220. doi: 10.1177/1533317518755332. Epub 2018 Jan 29.

PMID:
29378429
4.

G4941K substitution in the pore-lining S6 helix of the skeletal muscle ryanodine receptor increases RyR1 sensitivity to cytosolic and luminal Ca2.

Xu L, Mowrey DD, Chirasani VR, Wang Y, Pasek DA, Dokholyan NV, Meissner G.

J Biol Chem. 2018 Feb 9;293(6):2015-2028. doi: 10.1074/jbc.M117.803247. Epub 2017 Dec 18.

PMID:
29255089
5.

The structural basis of ryanodine receptor ion channel function.

Meissner G.

J Gen Physiol. 2017 Dec 4;149(12):1065-1089. doi: 10.1085/jgp.201711878. Epub 2017 Nov 9. Review.

6.

Consecutive Transformations of Tetrafluoropropenes: Hydrogermylation and Catalytic C-F Activation Steps at a Lewis Acidic Aluminum Fluoride.

Meißner G, Kretschmar K, Braun T, Kemnitz E.

Angew Chem Int Ed Engl. 2017 Dec 18;56(51):16338-16341. doi: 10.1002/anie.201707759. Epub 2017 Nov 23.

PMID:
28981989
7.

Two EF-hand motifs in ryanodine receptor calcium release channels contribute to isoform-specific regulation by calmodulin.

Xu L, Gomez AC, Pasek DA, Meissner G, Yamaguchi N.

Cell Calcium. 2017 Sep;66:62-70. doi: 10.1016/j.ceca.2017.05.013. Epub 2017 Jun 6.

8.

Ion-pulling simulations provide insights into the mechanisms of channel opening of the skeletal muscle ryanodine receptor.

Mowrey DD, Xu L, Mei Y, Pasek DA, Meissner G, Dokholyan NV.

J Biol Chem. 2017 Aug 4;292(31):12947-12958. doi: 10.1074/jbc.M116.760199. Epub 2017 Jun 5.

9.

Insecticidal activity of a recombinant knottin peptide from Loxosceles intermedia venom and recognition of these peptides as a conserved family in the genus.

Matsubara FH, Meissner GO, Herzig V, Justa HC, Dias BC, Trevisan-Silva D, Gremski LH, Gremski W, Senff-Ribeiro A, Chaim OM, King GF, Veiga SS.

Insect Mol Biol. 2017 Feb;26(1):25-34. doi: 10.1111/imb.12268. Epub 2016 Oct 15.

PMID:
27743460
10.

Molecular cloning and in silico characterization of knottin peptide, U2-SCRTX-Lit2, from brown spider (Loxosceles intermedia) venom glands.

Meissner GO, de Resende Lara PT, Scott LP, Braz AS, Chaves-Moreira D, Matsubara FH, Soares EM, Trevisan-Silva D, Gremski LH, Veiga SS, Chaim OM.

J Mol Model. 2016 Sep;22(9):196. doi: 10.1007/s00894-016-3067-0. Epub 2016 Aug 3.

PMID:
27488102
11.

Expression and immunological cross-reactivity of LALP3, a novel astacin-like metalloprotease from brown spider (Loxosceles intermedia) venom.

Morgon AM, Belisario-Ferrari MR, Trevisan-Silva D, Meissner GO, Vuitika L, Marin B, Tashima AK, Gremski LH, Gremski W, Senff-Ribeiro A, Veiga SS, Chaim OM.

Biochimie. 2016 Sep-Oct;128-129:8-19. doi: 10.1016/j.biochi.2016.06.003. Epub 2016 Jun 23.

PMID:
27343628
12.

Chromosome aberration associated with hippocampal impairment.

Haussmann R, Meissner G, Linn J, Hackmann K, Betcheva-Krajcir E, Tzschach A, Donix M.

Psychiatry Res Neuroimaging. 2016 Aug 30;254:1-2. doi: 10.1016/j.pscychresns.2016.05.007. Epub 2016 Jun 2. No abstract available.

PMID:
27285109
13.

Sex-specific regulation of Lgr3 in Drosophila neurons.

Meissner GW, Luo SD, Dias BG, Texada MJ, Baker BS.

Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):E1256-65. doi: 10.1073/pnas.1600241113. Epub 2016 Feb 16.

14.

Brown spider (Loxosceles genus) venom toxins: Evaluation of biological conservation by immune cross-reactivity.

Buch DR, Souza FN, Meissner GO, Morgon AM, Gremski LH, Ferrer VP, Trevisan-Silva D, Matsubara FH, Boia-Ferreira M, Sade YB, Chaves-Moreira D, Gremski W, Veiga SS, Chaim OM, Senff-Ribeiro A.

Toxicon. 2015 Dec 15;108:154-66. doi: 10.1016/j.toxicon.2015.09.041. Epub 2015 Oct 22.

PMID:
26474948
15.

mTOR signaling in mice with dysfunctional cardiac ryanodine receptor ion channel.

Huang TQ, Zou MX, Pasek DA, Meissner G.

J Receptor Ligand Channel Res. 2015;8:43-51.

16.

PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.

Xie L, Pi X, Townley-Tilson WH, Li N, Wehrens XH, Entman ML, Taffet GE, Mishra A, Peng J, Schisler JC, Meissner G, Patterson C.

J Clin Invest. 2015 Jul 1;125(7):2759-71. doi: 10.1172/JCI80369. Epub 2015 Jun 15.

17.

Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor.

Mei Y, Xu L, Mowrey DD, Mendez Giraldez R, Wang Y, Pasek DA, Dokholyan NV, Meissner G.

J Biol Chem. 2015 Jul 10;290(28):17535-45. doi: 10.1074/jbc.M115.659672. Epub 2015 May 21.

18.

Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2.

Lavorato M, Huang TQ, Iyer VR, Perni S, Meissner G, Franzini-Armstrong C.

J Muscle Res Cell Motil. 2015 Apr;36(2):205-14. doi: 10.1007/s10974-015-9405-5. Epub 2015 Feb 19.

PMID:
25694159
19.

Identification of the transporter responsible for sucrose accumulation in sugar beet taproots.

Jung B, Ludewig F, Schulz A, Meißner G, Wöstefeld N, Flügge UI, Pommerrenig B, Wirsching P, Sauer N, Koch W, Sommer F, Mühlhaus T, Schroda M, Cuin TA, Graus D, Marten I, Hedrich R, Neuhaus HE.

Nat Plants. 2015 Jan 8;1:14001. doi: 10.1038/nplants.2014.1.

PMID:
27246048
20.

IL-6/STAT3 signaling in mice with dysfunctional type-2 ryanodine receptor.

Huang TQ, Willis MS, Meissner G.

JAKSTAT. 2016 Mar 7;4(4):e1158379. doi: 10.1080/21623996.2016.1158379. eCollection 2015.

21.

Selecting ions by size in a calcium channel: the ryanodine receptor case study.

Gillespie D, Xu L, Meissner G.

Biophys J. 2014 Nov 18;107(10):2263-73. doi: 10.1016/j.bpj.2014.09.031.

22.

Inhibition of CaMKII does not attenuate cardiac hypertrophy in mice with dysfunctional ryanodine receptor.

Chakraborty A, Pasek DA, Huang TQ, Gomez AC, Yamaguchi N, Anderson ME, Meissner G.

PLoS One. 2014 Aug 5;9(8):e104338. doi: 10.1371/journal.pone.0104338. eCollection 2014.

23.

Central brain neurons expressing doublesex regulate female receptivity in Drosophila.

Zhou C, Pan Y, Robinett CC, Meissner GW, Baker BS.

Neuron. 2014 Jul 2;83(1):149-63. doi: 10.1016/j.neuron.2014.05.038.

24.

Pore dynamics and conductance of RyR1 transmembrane domain.

Shirvanyants D, Ramachandran S, Mei Y, Xu L, Meissner G, Dokholyan NV.

Biophys J. 2014 Jun 3;106(11):2375-84. doi: 10.1016/j.bpj.2014.04.023.

25.

A small subset of fruitless subesophageal neurons modulate early courtship in Drosophila.

Tran DH, Meissner GW, French RL, Baker BS.

PLoS One. 2014 Apr 16;9(4):e95472. doi: 10.1371/journal.pone.0095472. eCollection 2014.

26.

Recent advances in the understanding of brown spider venoms: From the biology of spiders to the molecular mechanisms of toxins.

Gremski LH, Trevisan-Silva D, Ferrer VP, Matsubara FH, Meissner GO, Wille AC, Vuitika L, Dias-Lopes C, Ullah A, de Moraes FR, Chávez-Olórtegui C, Barbaro KC, Murakami MT, Arni RK, Senff-Ribeiro A, Chaim OM, Veiga SS.

Toxicon. 2014 Jun;83:91-120. doi: 10.1016/j.toxicon.2014.02.023. Epub 2014 Mar 11. Review.

PMID:
24631373
27.

Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.

Yang Y, Guo T, Oda T, Chakraborty A, Chen L, Uchinoumi H, Knowlton AA, Fruen BR, Cornea RL, Meissner G, Bers DM.

Circ Res. 2014 Jan 17;114(2):295-306. doi: 10.1161/CIRCRESAHA.114.302857. Epub 2013 Nov 1.

28.

Cardiac calcium signalling pathologies associated with defective calmodulin regulation of type 2 ryanodine receptor.

Arnáiz-Cot JJ, Damon BJ, Zhang XH, Cleemann L, Yamaguchi N, Meissner G, Morad M.

J Physiol. 2013 Sep 1;591(17):4287-99. doi: 10.1113/jphysiol.2013.256123. Epub 2013 Jul 8.

29.

Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia.

Manno C, Figueroa L, Royer L, Pouvreau S, Lee CS, Volpe P, Nori A, Zhou J, Meissner G, Hamilton SL, Ríos E.

J Physiol. 2013 Sep 15;591(18):4439-57. doi: 10.1113/jphysiol.2013.259572. Epub 2013 Jun 24.

30.

A novel ICK peptide from the Loxosceles intermedia (brown spider) venom gland: cloning, heterologous expression and immunological cross-reactivity approaches.

Matsubara FH, Gremski LH, Meissner GO, Constantino Lopes ES, Gremski W, Senff-Ribeiro A, Chaim OM, Veiga SS.

Toxicon. 2013 Sep;71:147-58. doi: 10.1016/j.toxicon.2013.05.014. Epub 2013 Jun 8.

PMID:
23751278
31.

Cardiac hypertrophy associated with impaired regulation of cardiac ryanodine receptor by calmodulin and S100A1.

Yamaguchi N, Chakraborty A, Huang TQ, Xu L, Gomez AC, Pasek DA, Meissner G.

Am J Physiol Heart Circ Physiol. 2013 Jul 1;305(1):H86-94. doi: 10.1152/ajpheart.00144.2013. Epub 2013 May 10.

32.

Stabilization of the skeletal muscle ryanodine receptor ion channel-FKBP12 complex by the 1,4-benzothiazepine derivative S107.

Mei Y, Xu L, Kramer HF, Tomberlin GH, Townsend C, Meissner G.

PLoS One. 2013;8(1):e54208. doi: 10.1371/journal.pone.0054208. Epub 2013 Jan 17.

33.

Structural determinants of skeletal muscle ryanodine receptor gating.

Ramachandran S, Chakraborty A, Xu L, Mei Y, Samsó M, Dokholyan NV, Meissner G.

J Biol Chem. 2013 Mar 1;288(9):6154-65. doi: 10.1074/jbc.M112.433789. Epub 2013 Jan 14.

34.

Joint control of Drosophila male courtship behavior by motion cues and activation of male-specific P1 neurons.

Pan Y, Meissner GW, Baker BS.

Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10065-70. doi: 10.1073/pnas.1207107109. Epub 2012 May 29.

35.

Detection of calcium release via ryanodine receptors.

Eu JP, Meissner G.

Methods Mol Biol. 2012;798:373-82. doi: 10.1007/978-1-61779-343-1_21.

PMID:
22130848
36.

Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4.

Sun QA, Hess DT, Nogueira L, Yong S, Bowles DE, Eu J, Laurita KR, Meissner G, Stamler JS.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16098-103. doi: 10.1073/pnas.1109546108. Epub 2011 Sep 6.

37.

Functional dissection of the neural substrates for sexual behaviors in Drosophila melanogaster.

Meissner GW, Manoli DS, Chavez JF, Knapp JM, Lin TL, Stevens RJ, Mellert DJ, Tran DH, Baker BS.

Genetics. 2011 Sep;189(1):195-211. doi: 10.1534/genetics.111.129940. Epub 2011 Jul 29.

38.
39.

Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules.

Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95. doi: 10.1152/ajpheart.00719.2010. Epub 2011 Mar 18.

40.

Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1.

Yamaguchi N, Prosser BL, Ghassemi F, Xu L, Pasek DA, Eu JP, Hernández-Ochoa EO, Cannon BR, Wilder PT, Lovering RM, Weber D, Melzer W, Schneider MF, Meissner G.

Am J Physiol Cell Physiol. 2011 May;300(5):C998-C1012. doi: 10.1152/ajpcell.00370.2010. Epub 2011 Feb 2.

41.

Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum.

Loy RE, Orynbayev M, Xu L, Andronache Z, Apostol S, Zvaritch E, MacLennan DH, Meissner G, Melzer W, Dirksen RT.

J Gen Physiol. 2011 Jan;137(1):43-57. doi: 10.1085/jgp.201010523. Epub 2010 Dec 13.

42.

Calculus-detection technologies and their clinical application.

Meissner G, Kocher T.

Periodontol 2000. 2011 Feb;55(1):189-204. doi: 10.1111/j.1600-0757.2010.00379.x. Review. No abstract available.

PMID:
21134235
43.

Regulation of ryanodine receptors by sphingosylphosphorylcholine: involvement of both calmodulin-dependent and -independent mechanisms.

Kovacs E, Xu L, Pasek DA, Liliom K, Meissner G.

Biochem Biophys Res Commun. 2010 Oct 15;401(2):281-6. doi: 10.1016/j.bbrc.2010.09.050. Epub 2010 Sep 17.

44.

Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene.

Zhou H, Lillis S, Loy RE, Ghassemi F, Rose MR, Norwood F, Mills K, Al-Sarraj S, Lane RJ, Feng L, Matthews E, Sewry CA, Abbs S, Buk S, Hanna M, Treves S, Dirksen RT, Meissner G, Muntoni F, Jungbluth H.

Neuromuscul Disord. 2010 Mar;20(3):166-73. doi: 10.1016/j.nmd.2009.12.005. Epub 2010 Jan 18.

45.

Regulation of Ryanodine Receptor Ion Channels Through Posttranslational Modifications.

Meissner G.

Curr Top Membr. 2010;66:91-113. No abstract available.

46.

Midline crossing by gustatory receptor neuron axons is regulated by fruitless, doublesex and the Roundabout receptors.

Mellert DJ, Knapp JM, Manoli DS, Meissner GW, Baker BS.

Development. 2010 Jan;137(2):323-32. doi: 10.1242/dev.045047.

47.

Astacin-like metalloproteases are a gene family of toxins present in the venom of different species of the brown spider (genus Loxosceles).

Trevisan-Silva D, Gremski LH, Chaim OM, da Silveira RB, Meissner GO, Mangili OC, Barbaro KC, Gremski W, Veiga SS, Senff-Ribeiro A.

Biochimie. 2010 Jan;92(1):21-32. doi: 10.1016/j.biochi.2009.10.003. Epub 2009 Oct 30.

PMID:
19879318
48.

Silencing genes of sarcoplasmic reticulum proteins clarifies their roles in excitation-contraction coupling.

Meissner G, Wang Y, Xu L, Eu JP.

J Physiol. 2009 Jul 1;587(Pt 13):3089-90. doi: 10.1113/jphysiol.2009.171835. No abstract available.

49.

A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1).

Ramachandran S, Serohijos AW, Xu L, Meissner G, Dokholyan NV.

PLoS Comput Biol. 2009 Apr;5(4):e1000367. doi: 10.1371/journal.pcbi.1000367. Epub 2009 Apr 24.

50.

Regulation of the cardiac muscle ryanodine receptor by O(2) tension and S-nitrosoglutathione.

Sun J, Yamaguchi N, Xu L, Eu JP, Stamler JS, Meissner G.

Biochemistry. 2008 Dec 30;47(52):13985-90. doi: 10.1021/bi8012627.

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