Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 480

1.

The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis.

Di Stefano B, Luo EC, Haggerty C, Aigner S, Charlton J, Brumbaugh J, Ji F, Rabano Jiménez I, Clowers KJ, Huebner AJ, Clement K, Lipchina I, de Kort MAC, Anselmo A, Pulice J, Gerli MFM, Gu H, Gygi SP, Sadreyev RI, Meissner A, Yeo GW, Hochedlinger K.

Cell Stem Cell. 2019 Sep 27. pii: S1934-5909(19)30385-6. doi: 10.1016/j.stem.2019.08.018. [Epub ahead of print]

PMID:
31588046
2.

Differential regulation of OCT4 targets facilitates reacquisition of pluripotency.

Thakurela S, Sindhu C, Yurkovsky E, Riemenschneider C, Smith ZD, Nachman I, Meissner A.

Nat Commun. 2019 Sep 30;10(1):4444. doi: 10.1038/s41467-019-11741-5.

3.

Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression.

Tsankov AM, Wadsworth MH 2nd, Akopian V, Charlton J, Allon SJ, Arczewska A, Mead BE, Drake RS, Smith ZD, Mikkelsen TS, Shalek AK, Meissner A.

Development. 2019 Sep 12;146(19). pii: dev174722. doi: 10.1242/dev.174722.

PMID:
31515224
4.

Nanopype: a modular and scalable nanopore data processing pipeline.

Giesselmann P, Hetzel S, Müller FJ, Meissner A, Kretzmer H.

Bioinformatics. 2019 Aug 6. pii: btz547. doi: 10.1093/bioinformatics/btz547. [Epub ahead of print] No abstract available.

PMID:
31386105
5.

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors.

Jönsson ME, Ludvik Brattås P, Gustafsson C, Petri R, Yudovich D, Pircs K, Verschuere S, Madsen S, Hansson J, Larsson J, Månsson R, Meissner A, Jakobsson J.

Nat Commun. 2019 Jul 18;10(1):3182. doi: 10.1038/s41467-019-11150-8.

6.

Nanopype: A modular and scalable nanopore data processing pipeline.

Giesselmann P, Hetzel S, Müller FJ, Meissner A, Kretzmer H.

Bioinformatics. 2019 Jun 13. pii: btz461. doi: 10.1093/bioinformatics/btz461. [Epub ahead of print]

PMID:
31192347
7.

Role of the S1P pathway and inhibition by fingolimod in preventing hemorrhagic transformation after stroke.

Salas-Perdomo A, Miró-Mur F, Gallizioli M, Brait VH, Justicia C, Meissner A, Urra X, Chamorro A, Planas AM.

Sci Rep. 2019 Jun 5;9(1):8309. doi: 10.1038/s41598-019-44845-5.

8.

Clinical impact of rapid species identification from positive blood cultures with same-day phenotypic antimicrobial susceptibility testing on the management and outcome of bloodstream infections.

Ehren K, Meißner A, Jazmati N, Wille J, Jung N, Vehreschild JJ, Hellmich M, Seifert H.

Clin Infect Dis. 2019 May 16. pii: ciz406. doi: 10.1093/cid/ciz406. [Epub ahead of print]

PMID:
31094414
9.

Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia.

Gaiti F, Chaligne R, Gu H, Brand RM, Kothen-Hill S, Schulman RC, Grigorev K, Risso D, Kim KT, Pastore A, Huang KY, Alonso A, Sheridan C, Omans ND, Biederstedt E, Clement K, Wang L, Felsenfeld JA, Bhavsar EB, Aryee MJ, Allan JN, Furman R, Gnirke A, Wu CJ, Meissner A, Landau DA.

Nature. 2019 May;569(7757):576-580. doi: 10.1038/s41586-019-1198-z. Epub 2019 May 15.

PMID:
31092926
10.

Molecular recording of mammalian embryogenesis.

Chan MM, Smith ZD, Grosswendt S, Kretzmer H, Norman TM, Adamson B, Jost M, Quinn JJ, Yang D, Jones MG, Khodaverdian A, Yosef N, Meissner A, Weissman JS.

Nature. 2019 Jun;570(7759):77-82. doi: 10.1038/s41586-019-1184-5. Epub 2019 May 13.

PMID:
31086336
11.

Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition.

Modic M, Grosch M, Rot G, Schirge S, Lepko T, Yamazaki T, Lee FCY, Rusha E, Shaposhnikov D, Palo M, Merl-Pham J, Cacchiarelli D, Rogelj B, Hauck SM, von Mering C, Meissner A, Lickert H, Hirose T, Ule J, Drukker M.

Mol Cell. 2019 Jun 6;74(5):951-965.e13. doi: 10.1016/j.molcel.2019.03.041. Epub 2019 Apr 29.

12.

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL.

Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, Furman RR, Gnirke A, Wu CJ, Melnick AM, Meissner A, Bernstein BE, Abdel-Wahab O, Landau DA.

Nat Commun. 2019 Apr 23;10(1):1874. doi: 10.1038/s41467-019-09645-5.

13.

The relative importance of genetic parenthood.

Hendriks S, van Wely M, D'Hooghe TM, Meissner A, Mol F, Peeraer K, Repping S, Dancet EAF.

Reprod Biomed Online. 2019 Jul;39(1):103-110. doi: 10.1016/j.rbmo.2019.02.008. Epub 2019 Mar 12.

PMID:
31006544
14.

PDGF-B Is Required for Development of the Glymphatic System.

Munk AS, Wang W, Bèchet NB, Eltanahy AM, Cheng AX, Sigurdsson B, Benraiss A, Mäe MA, Kress BT, Kelley DH, Betsholtz C, Møllgård K, Meissner A, Nedergaard M, Lundgaard I.

Cell Rep. 2019 Mar 12;26(11):2955-2969.e3. doi: 10.1016/j.celrep.2019.02.050.

15.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2019 Feb 11;35(2):330-332. doi: 10.1016/j.ccell.2019.01.012. No abstract available.

16.

T-Cell Accumulation in the Hypertensive Brain: A Role for Sphingosine-1-Phosphate-Mediated Chemotaxis.

Don-Doncow N, Vanherle L, Zhang Y, Meissner A.

Int J Mol Sci. 2019 Jan 28;20(3). pii: E537. doi: 10.3390/ijms20030537.

17.

Use of Fertility Preservation Among a Cohort of Transgirls in the Netherlands.

Brik T, Vrouenraets LJJJ, Schagen SEE, Meissner A, de Vries MC, Hannema SE.

J Adolesc Health. 2019 May;64(5):589-593. doi: 10.1016/j.jadohealth.2018.11.008. Epub 2019 Jan 26.

PMID:
30691936
18.

Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope®.

Seidel D, Meißner A, Lackner M, Piepenbrock E, Salmanton-García J, Stecher M, Mellinghoff S, Hamprecht A, Durán Graeff L, Köhler P, Cheng MP, Denis J, Chedotal I, Chander J, Pakstis DL, Los-Arcos I, Slavin M, Montagna MT, Caggiano G, Mares M, Trauth J, Aurbach U, Vehreschild MJGT, Vehreschild JJ, Duarte RF, Herbrecht R, Wisplinghoff H, Cornely OA.

Crit Rev Microbiol. 2019 Feb;45(1):1-21. doi: 10.1080/1040841X.2018.1514366. Epub 2019 Jan 10. Erratum in: Crit Rev Microbiol. 2019 Feb 18;:1.

PMID:
30628529
19.

Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.

Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL.

Nat Neurosci. 2019 Jan;22(1):37-46. doi: 10.1038/s41593-018-0291-1. Epub 2018 Dec 17.

20.

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance.

Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, Rai G, Maloney DJ, Jadhav A, Simeonov A, Wagle N, Brown M, Meissner A, Sicinski P, Jaffe JD, Jeselsohn R, Gimelbrant AA, Michor F, Polyak K.

Cancer Cell. 2018 Dec 10;34(6):939-953.e9. doi: 10.1016/j.ccell.2018.10.014. Epub 2018 Nov 21. Erratum in: Cancer Cell. 2019 Feb 11;35(2):330-332.

PMID:
30472020
21.

Targets and genomic constraints of ectopic Dnmt3b expression.

Zhang Y, Charlton J, Karnik R, Beerman I, Smith ZD, Gu H, Boyle P, Mi X, Clement K, Pop R, Gnirke A, Rossi DJ, Meissner A.

Elife. 2018 Nov 23;7. pii: e40757. doi: 10.7554/eLife.40757.

22.

Paying PIs from grants blocks talent and diversity.

Bernstein E, Meissner A, Ramalho-Santos M.

Nature. 2018 Nov;563(7731):325. doi: 10.1038/d41586-018-07382-1. No abstract available.

PMID:
30429558
23.

Orchidopexy for bilateral undescended testes: A multicentre study on its effects on fertility and comparison of two fixation techniques.

Uijldert M, Meißner A, Kuijper CF, Repping S, de Jong TPVM, Chrzan RJ.

Andrologia. 2019 Apr;51(3):e13194. doi: 10.1111/and.13194. Epub 2018 Nov 8.

PMID:
30411395
24.

Comparative genomic analysis of embryonic, lineage-converted and stem cell-derived motor neurons.

Ichida JK, Staats KA, Davis-Dusenbery BN, Clement K, Galloway KE, Babos KN, Shi Y, Son EY, Kiskinis E, Atwater N, Gu H, Gnirke A, Meissner A, Eggan K.

Development. 2018 Nov 21;145(22). pii: dev168617. doi: 10.1242/dev.168617.

25.

Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming Outcome.

Cacchiarelli D, Qiu X, Srivatsan S, Manfredi A, Ziller M, Overbey E, Grimaldi A, Grimsby J, Pokharel P, Livak KJ, Li S, Meissner A, Mikkelsen TS, Rinn JL, Trapnell C.

Cell Syst. 2018 Sep 26;7(3):258-268.e3. doi: 10.1016/j.cels.2018.07.006. Epub 2018 Sep 5.

26.

Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.

Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K.

Nat Methods. 2018 Sep;15(9):732-740. doi: 10.1038/s41592-018-0104-1. Epub 2018 Aug 20.

27.

Chromatin-dependent allosteric regulation of DNMT3A activity by MeCP2.

Rajavelu A, Lungu C, Emperle M, Dukatz M, Bröhm A, Broche J, Hanelt I, Parsa E, Schiffers S, Karnik R, Meissner A, Carell T, Rathert P, Jurkowska RZ, Jeltsch A.

Nucleic Acids Res. 2018 Sep 28;46(17):9044-9056. doi: 10.1093/nar/gky715.

28.

Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress.

Sacerdoti D, Singh SP, Schragenheim J, Bellner L, Vanella L, Raffaele M, Meissner A, Grant I, Favero G, Rezzani R, Rodella LF, Bamshad D, Lebovics E, Abraham NG.

Int J Hepatol. 2018 Jul 2;2018:3484107. doi: 10.1155/2018/3484107. eCollection 2018.

29.

Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming.

Schwarz BA, Cetinbas M, Clement K, Walsh RM, Cheloufi S, Gu H, Langkabel J, Kamiya A, Schorle H, Meissner A, Sadreyev RI, Hochedlinger K.

Cell Stem Cell. 2018 Aug 2;23(2):289-305.e5. doi: 10.1016/j.stem.2018.06.013. Epub 2018 Jul 12.

30.

The emerging alliance of sphingosine-1-phosphate signalling and immune cells: from basic mechanisms to implications in hypertension.

Don-Doncow N, Zhang Y, Matuskova H, Meissner A.

Br J Pharmacol. 2019 Jun;176(12):1989-2001. doi: 10.1111/bph.14381. Epub 2018 Jul 3. Review.

PMID:
29856066
31.

An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition.

Du P, Pirouz M, Choi J, Huebner AJ, Clement K, Meissner A, Hochedlinger K, Gregory RI.

Cell Stem Cell. 2018 Jun 1;22(6):851-864.e5. doi: 10.1016/j.stem.2018.04.021. Epub 2018 May 24.

32.

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission.

Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, Madison J, Muller M, Arlotta P, Fu Z, Feng G, Eggan K.

Cell Rep. 2018 May 22;23(8):2509-2523. doi: 10.1016/j.celrep.2018.04.066.

33.

EET enhances renal function in obese mice resulting in restoration of HO-1-Mfn1/2 signaling, and decrease in hypertension through inhibition of sodium chloride co-transporter.

Schragenheim J, Bellner L, Cao J, Singh SP, Bamshad D, McClung JA, Maayan O, Meissner A, Grant I, Stier CT Jr, Abraham NG.

Prostaglandins Other Lipid Mediat. 2018 Jul;137:30-39. doi: 10.1016/j.prostaglandins.2018.05.008. Epub 2018 May 19.

34.

Metabolism and Disposition of Siponimod, a Novel Selective S1P1/S1P5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism.

Glaenzel U, Jin Y, Nufer R, Li W, Schroer K, Adam-Stitah S, Peter van Marle S, Legangneux E, Borell H, James AD, Meissner A, Camenisch G, Gardin A.

Drug Metab Dispos. 2018 Jul;46(7):1001-1013. doi: 10.1124/dmd.117.079574. Epub 2018 May 7.

PMID:
29735753
35.

[Heart Failure Despite Low BNP-Level: Paradoxon or Pathfinder? - - A Case of Pericarditis constrictiva].

Dopp H, Maagh P, Meissner A.

Dtsch Med Wochenschr. 2018 May;143(10):731-734. doi: 10.1055/a-0600-1645. Epub 2018 May 4. German.

PMID:
29727888
36.

The risk of TESE-induced hypogonadism: a systematic review and meta-analysis.

Eliveld J, van Wely M, Meißner A, Repping S, van der Veen F, van Pelt AMM.

Hum Reprod Update. 2018 Jul 1;24(4):442-454. doi: 10.1093/humupd/dmy015.

37.

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs.

Pasque V, Karnik R, Chronis C, Petrella P, Langerman J, Bonora G, Song J, Vanheer L, Sadhu Dimashkie A, Meissner A, Plath K.

Stem Cell Reports. 2018 May 8;10(5):1537-1550. doi: 10.1016/j.stemcr.2018.03.019. Epub 2018 Apr 19.

38.

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ.

Cell. 2018 Apr 19;173(3):624-633.e8. doi: 10.1016/j.cell.2018.03.026. Epub 2018 Apr 12.

39.

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ.

Cell Stem Cell. 2018 Apr 5;22(4):575-588.e7. doi: 10.1016/j.stem.2018.03.012.

40.

Author Correction: Global delay in nascent strand DNA methylation.

Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A.

Nat Struct Mol Biol. 2018 Apr;25(4):355. doi: 10.1038/s41594-018-0055-3.

PMID:
29581568
41.

Dissecting the Functional Consequences of De Novo DNA Methylation Dynamics in Human Motor Neuron Differentiation and Physiology.

Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, Kiskinis E.

Cell Stem Cell. 2018 Apr 5;22(4):559-574.e9. doi: 10.1016/j.stem.2018.02.012. Epub 2018 Mar 15.

42.

Global delay in nascent strand DNA methylation.

Charlton J, Downing TL, Smith ZD, Gu H, Clement K, Pop R, Akopian V, Klages S, Santos DP, Tsankov AM, Timmermann B, Ziller MJ, Kiskinis E, Gnirke A, Meissner A.

Nat Struct Mol Biol. 2018 Apr;25(4):327-332. doi: 10.1038/s41594-018-0046-4. Epub 2018 Mar 12. Erratum in: Nat Struct Mol Biol. 2018 Mar 26;:.

43.

Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain.

Janssens S, Schotsaert M, Karnik R, Balasubramaniam V, Dejosez M, Meissner A, García-Sastre A, Zwaka TP.

mSystems. 2018 Feb 6;3(1). pii: e00219-17. doi: 10.1128/mSystems.00219-17. eCollection 2018 Jan-Feb.

44.

Genome-wide tracking of dCas9-methyltransferase footprints.

Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A.

Nat Commun. 2018 Feb 9;9(1):597. doi: 10.1038/s41467-017-02708-5.

45.

Genetic determinants and epigenetic effects of pioneer-factor occupancy.

Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A.

Nat Genet. 2018 Feb;50(2):250-258. doi: 10.1038/s41588-017-0034-3. Epub 2018 Jan 22.

46.

Point-by-point versus multisite electrode mapping in VT ablation: does freedom from VT recurrences depend on mapping catheter? An observational study.

Maagh P, Christoph A, Müller MS, Dopp H, Plehn G, Meissner A.

J Interv Card Electrophysiol. 2018 Mar;51(2):169-181. doi: 10.1007/s10840-018-0311-9. Epub 2018 Jan 22.

PMID:
29356922
47.

High-Density Mapping in Ventricular Tachycardia Ablation: A PentaRay® Study.

Maagh P, Christoph A, Dopp H, Mueller MS, Plehn G, Meissner A.

Cardiol Res. 2017 Dec;8(6):293-303. doi: 10.14740/cr636w. Epub 2017 Dec 22.

48.

Is wrist splint more effective than forearm band for lateral epicondylitis?

Meissner A, Vives MI, Román J, Meissner A.

Medwave. 2017 Dec 28;17(9):e7124. doi: 10.5867/medwave.2017.09.7124. Review. Spanish, English.

PMID:
29286358
50.

Development of the testis in pre-pubertal boys with cancer after biopsy for fertility preservation.

Uijldert M, Meißner A, de Melker AA, van Pelt AMM, van de Wetering MD, van Rijn RR, van Wely M, van der Veen F, Repping S.

Hum Reprod. 2017 Dec 1;32(12):2366-2372. doi: 10.1093/humrep/dex306.

PMID:
29040511

Supplemental Content

Loading ...
Support Center