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Items: 8

1.

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement.

Vasta JD, Corona CR, Wilkinson J, Zimprich CA, Hartnett JR, Ingold MR, Zimmerman K, Machleidt T, Kirkland TA, Huwiler KG, Ohana RF, Slater M, Otto P, Cong M, Wells CI, Berger BT, Hanke T, Glas C, Ding K, Drewry DH, Huber KVM, Willson TM, Knapp S, Müller S, Meisenheimer PL, Fan F, Wood KV, Robers MB.

Cell Chem Biol. 2018 Feb 15;25(2):206-214.e11. doi: 10.1016/j.chembiol.2017.10.010. Epub 2017 Nov 22.

2.

Novel heterocyclic analogues of firefly luciferin.

Woodroofe CC, Meisenheimer PL, Klaubert DH, Kovic Y, Rosenberg JC, Behney CE, Southworth TL, Branchini BR.

Biochemistry. 2012 Dec 11;51(49):9807-13. doi: 10.1021/bi301411d. Epub 2012 Nov 29.

PMID:
23164087
3.

Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate.

Hall MP, Unch J, Binkowski BF, Valley MP, Butler BL, Wood MG, Otto P, Zimmerman K, Vidugiris G, Machleidt T, Robers MB, Benink HA, Eggers CT, Slater MR, Meisenheimer PL, Klaubert DH, Fan F, Encell LP, Wood KV.

ACS Chem Biol. 2012 Nov 16;7(11):1848-57. doi: 10.1021/cb3002478. Epub 2012 Aug 30.

4.

Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates.

Cali JJ, Ma D, Wood MG, Meisenheimer PL, Klaubert DH.

Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1115-30. doi: 10.1517/17425255.2012.695345. Epub 2012 Jun 11. Review.

PMID:
22686499
5.

Proluciferin acetals as bioluminogenic substrates for cytochrome P450 activity and probes for CYP3A inhibition.

Meisenheimer PL, Uyeda HT, Ma D, Sobol M, McDougall MG, Corona C, Simpson D, Klaubert DH, Cali JJ.

Drug Metab Dispos. 2011 Dec;39(12):2403-10. doi: 10.1124/dmd.111.041541. Epub 2011 Sep 2.

PMID:
21890735
6.

N-Alkylated 6'-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays.

Woodroofe CC, Shultz JW, Wood MG, Osterman J, Cali JJ, Daily WJ, Meisenheimer PL, Klaubert DH.

Biochemistry. 2008 Sep 30;47(39):10383-93. doi: 10.1021/bi800505u. Epub 2008 Sep 5.

PMID:
18771284
7.

Nucleoprotein photo-cross-linking using halopyrimidine-substituted RNAs.

Meisenheimer KM, Meisenheimer PL, Koch TH.

Methods Enzymol. 2000;318:88-104. No abstract available.

PMID:
10889982
8.

High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein.

Meisenheimer KM, Meisenheimer PL, Willis MC, Koch TH.

Nucleic Acids Res. 1996 Mar 1;24(5):981-2. No abstract available.

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