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Items: 1 to 50 of 248

1.

Abdominal ultrasound for diagnosing abdominal tuberculosis or disseminated tuberculosis with abdominal involvement in HIV-positive individuals.

Van Hoving DJ, Griesel R, Meintjes G, Takwoingi Y, Maartens G, Ochodo EA.

Cochrane Database Syst Rev. 2019 Sep 30;9:CD012777. doi: 10.1002/14651858.CD012777.pub2.

2.

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients.

Schutz C, Ward A, Burton R, Nicol MP, Blumenthal L, Meintjes G, Kerkhoff AD.

South Afr J HIV Med. 2019 Aug 28;20(1):978. doi: 10.4102/sajhivmed.v20i1.978. eCollection 2019.

3.

Cytomegalovirus viremia associated with increased mortality in cryptococcal meningitis in sub-Saharan Africa.

Skipper CP, Schleiss MR, Bangdiwala AS, Hernandez-Alvarado N, Taseera K, Nabeta HW, Musubire AK, Lofgren SM, Wiesner DL, Rhein J, Rajasingham R, Schutz C, Meintjes G, Muzoora C, Meya DB, Boulware DR; COAT Team.

Clin Infect Dis. 2019 Sep 1. pii: ciz864. doi: 10.1093/cid/ciz864. [Epub ahead of print]

PMID:
31504335
4.

Key considerations in the pharmacotherapy of tuberculous meningitis.

Wasserman S, Davis A, Wilkinson RJ, Meintjes G.

Expert Opin Pharmacother. 2019 Oct;20(15):1791-1795. doi: 10.1080/14656566.2019.1638912. Epub 2019 Jul 15. No abstract available.

PMID:
31305179
5.

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study.

Schutz C, Barr D, Andrade BB, Shey M, Ward A, Janssen S, Burton R, Wilkinson KA, Sossen B, Fukutani KF, Nicol M, Maartens G, Wilkinson RJ, Meintjes G.

PLoS Med. 2019 Jul 5;16(7):e1002840. doi: 10.1371/journal.pmed.1002840. eCollection 2019 Jul.

6.

Management of active tuberculosis in adults with HIV.

Meintjes G, Brust JCM, Nuttall J, Maartens G.

Lancet HIV. 2019 Jul;6(7):e463-e474. doi: 10.1016/S2352-3018(19)30154-7. Review.

PMID:
31272663
7.

Low-cerebrospinal fluid white cell counts and mortality in HIV-associated pneumococcal meningitis.

Tenforde MW, Meintjes G, Mokomane M, Harrison TS, Mine M, Jarvis JN.

AIDS. 2019 Jul 15;33(9):1539-1541. doi: 10.1097/QAD.0000000000002241. No abstract available.

PMID:
31259771
8.

Meningitis: a frequently fatal diagnosis in Africa.

von Gottberg A, Meintjes G.

Lancet Infect Dis. 2019 Jul;19(7):676-678. doi: 10.1016/S1473-3099(19)30111-2. No abstract available.

9.

Invariant Natural Killer T cell dynamics in HIV-associated tuberculosis.

Walker NF, Opondo C, Meintjes G, Jhilmeet N, Friedland JS, Elkington PT, Wilkinson RJ, Wilkinson KA.

Clin Infect Dis. 2019 Jun 12. pii: ciz501. doi: 10.1093/cid/ciz501. [Epub ahead of print]

10.

Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study.

Broger T, Sossen B, du Toit E, Kerkhoff AD, Schutz C, Ivanova Reipold E, Ward A, Barr DA, Macé A, Trollip A, Burton R, Ongarello S, Pinter A, Lowary TL, Boehme C, Nicol MP, Meintjes G, Denkinger CM.

Lancet Infect Dis. 2019 Aug;19(8):852-861. doi: 10.1016/S1473-3099(19)30001-5. Epub 2019 May 30.

11.

Linezolid resistance in patients with drug-resistant TB and treatment failure in South Africa.

Wasserman S, Louw G, Ramangoaela L, Barber G, Hayes C, Omar SV, Maartens G, Barry C, Song T, Meintjes G.

J Antimicrob Chemother. 2019 Aug 1;74(8):2377-2384. doi: 10.1093/jac/dkz206.

12.

Prednisone for Prevention of Paradoxical Tuberculosis-Associated IRIS. Reply.

Meintjes G, Stek C, Maartens G.

N Engl J Med. 2019 May 2;380(18):1781. doi: 10.1056/NEJMc1900116. No abstract available.

PMID:
31042844
13.

The Contribution of Kaposi's Sarcoma-Associated Herpesvirus to Mortality in Hospitalized Human Immunodeficiency Virus-Infected Patients Being Investigated for Tuberculosis in South Africa.

Blumenthal MJ, Schutz C, Barr D, Locketz M, Marshall V, Whitby D, Katz AA, Uldrick T, Meintjes G, Schäfer G.

J Infect Dis. 2019 Jul 31;220(5):841-851. doi: 10.1093/infdis/jiz180.

PMID:
31004430
14.

Inadequate diagnostics: the case to move beyond the bacilli for detection of meningitis due to Mycobacterium tuberculosis.

Bahr NC, Meintjes G, Boulware DR.

J Med Microbiol. 2019 May;68(5):755-760. doi: 10.1099/jmm.0.000975. Epub 2019 Apr 17.

PMID:
30994435
15.

AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study.

Ponatshego PL, Lawrence DS, Youssouf N, Molloy SF, Alufandika M, Bango F, Boulware DR, Chawinga C, Dziwani E, Gondwe E, Hlupeni A, Hosseinipour MC, Kanyama C, Meya DB, Mosepele M, Muthoga C, Muzoora CK, Mwandumba H, Ndhlovu CE, Rajasingham R, Sayed S, Shamu S, Tsholo K, Tugume L, Williams D, Maheswaran H, Shiri T, Boyer-Chammard T, Loyse A, Chen T, Wang D, Lortholary O, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN, Niessen LW.

BMJ Open. 2019 Apr 1;9(4):e026288. doi: 10.1136/bmjopen-2018-026288.

16.

Managing HIV-associated tuberculosis in the dolutegravir era.

Maartens G, Meintjes G.

Clin Infect Dis. 2019 Mar 25. pii: ciz259. doi: 10.1093/cid/ciz259. [Epub ahead of print] No abstract available.

PMID:
30906946
17.

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center.

Van Hoving DJ, Lahri S, Lategan HJ, Nicol MP, Maartens G, Meintjes G.

J Acquir Immune Defic Syndr. 2019 May 1;81(1):e10-e14. doi: 10.1097/QAI.0000000000002002.

PMID:
30865176
18.

The Mouse Inhalation Model of Cryptococcus neoformans Infection Recapitulates Strain Virulence in Humans and Shows that Closely Related Strains Can Possess Differential Virulence.

Mukaremera L, McDonald TR, Nielsen JN, Molenaar CJ, Akampurira A, Schutz C, Taseera K, Muzoora C, Meintjes G, Meya DB, Boulware DR, Nielsen K.

Infect Immun. 2019 Apr 23;87(5). pii: e00046-19. doi: 10.1128/IAI.00046-19. Print 2019 Mar.

PMID:
30833336
19.

Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.

Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN.

Trials. 2019 Jan 14;20(1):48. doi: 10.1186/s13063-018-3155-9.

20.

Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection.

Wasserman S, Denti P, Brust JCM, Abdelwahab M, Hlungulu S, Wiesner L, Norman J, Sirgel FA, Warren RM, Esmail A, Dheda K, Gandhi NR, Meintjes G, Maartens G.

Antimicrob Agents Chemother. 2019 Feb 26;63(3). pii: e02164-18. doi: 10.1128/AAC.02164-18. Print 2019 Mar.

21.

Blood neutrophil counts in HIV-infected patients with cryptococcal meningitis: Association with mortality.

Musubire AK, Meya DB, Rhein J, Meintjes G, Bohjanen PR, Nuwagira E, Muzoora C, Boulware DR, Hullsiek KH; COAT and ASTRO trial teams.

PLoS One. 2018 Dec 31;13(12):e0209337. doi: 10.1371/journal.pone.0209337. eCollection 2018.

22.

Remembering the Host in Tuberculosis Drug Development.

Frank DJ, Horne DJ, Dutta NK, Shaku MT, Madensein R, Hawn TR, Steyn AJC, Karakousis PC, Kana BD, Meintjes G, Laughon B, Tanvir Z.

J Infect Dis. 2019 Apr 19;219(10):1518-1524. doi: 10.1093/infdis/jiy712.

PMID:
30590592
23.

A Clinical Prediction Rule for Protease Inhibitor Resistance in Patients Failing Second-Line Antiretroviral Therapy.

Cohen K, Stewart A, Kengne AP, Leisegang R, Coetsee M, Maharaj S, Dunn L, Hislop M, van Zyl G, Meintjes G, Maartens G.

J Acquir Immune Defic Syndr. 2019 Mar 1;80(3):325-329. doi: 10.1097/QAI.0000000000001923.

PMID:
30531296
24.

Appropriate clinical use of darunavir 800 mg.

Moorhouse MA, Carmona S, Davies N, Dlamini S, van Vuuren C, Manzini T, Mathe M, Moosa Y, Nash J, Nel J, Pakade Y, Woods J, van Zyl G, Conradie F, Venter F, Meintjes G.

South Afr J HIV Med. 2018 Oct 18;19(1):918. doi: 10.4102/sajhivmed.v19i1.918. eCollection 2018. No abstract available.

25.

Southern African HIV Clinicians Society Guidance on the use of dolutegravir in first-line antiretroviral therapy.

Moorhouse MA, Carmona S, Davies N, Dlamini S, van Vuuren C, Manzini T, Mathe M, Moosa Y, Nash J, Nel J, Pakade Y, Woods J, van Zyl G, Conradie F, Venter F, Meintjes G.

South Afr J HIV Med. 2018 Oct 17;19(1):917. doi: 10.4102/sajhivmed.v19i1.917. eCollection 2018. No abstract available.

26.

AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.

Lawrence DS, Youssouf N, Molloy SF, Alanio A, Alufandika M, Boulware DR, Boyer-Chammard T, Chen T, Dromer F, Hlupeni A, Hope W, Hosseinipour MC, Kanyama C, Lortholary O, Loyse A, Meya DB, Mosepele M, Muzoora C, Mwandumba HC, Ndhlovu CE, Niessen L, Schutz C, Stott KE, Wang D, Lalloo DG, Meintjes G, Jaffar S, Harrison TS, Jarvis JN.

Trials. 2018 Nov 23;19(1):649. doi: 10.1186/s13063-018-3026-4. Erratum in: Trials. 2019 Jan 14;20(1):48.

27.

Prednisone for the Prevention of Paradoxical Tuberculosis-Associated IRIS.

Meintjes G, Stek C, Blumenthal L, Thienemann F, Schutz C, Buyze J, Ravinetto R, van Loen H, Nair A, Jackson A, Colebunders R, Maartens G, Wilkinson RJ, Lynen L; PredART Trial Team.

N Engl J Med. 2018 Nov 15;379(20):1915-1925. doi: 10.1056/NEJMoa1800762.

28.

The Immune Mechanisms of Lung Parenchymal Damage in Tuberculosis and the Role of Host-Directed Therapy.

Stek C, Allwood B, Walker NF, Wilkinson RJ, Lynen L, Meintjes G.

Front Microbiol. 2018 Oct 30;9:2603. doi: 10.3389/fmicb.2018.02603. eCollection 2018. Review.

29.

A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.

Daskapan A, Idrus LR, Postma MJ, Wilffert B, Kosterink JGW, Stienstra Y, Touw DJ, Andersen AB, Bekker A, Denti P, Hemanth Kumar AK, Jeremiah K, Kwara A, McIlleron H, Meintjes G, van Oosterhout JJ, Ramachandran G, Rockwood N, Wilkinson RJ, van der Werf TS, Alffenaar JC.

Clin Pharmacokinet. 2019 Jun;58(6):747-766. doi: 10.1007/s40262-018-0716-8. Review.

30.

High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen.

Ndjeka N, Schnippel K, Master I, Meintjes G, Maartens G, Romero R, Padanilam X, Enwerem M, Chotoo S, Singh N, Hughes J, Variava E, Ferreira H, Te Riele J, Ismail N, Mohr E, Bantubani N, Conradie F.

Eur Respir J. 2018 Dec 20;52(6). pii: 1801528. doi: 10.1183/13993003.01528-2018. Print 2018 Dec.

PMID:
30361246
31.

HIV-Associated Cryptococcal Meningitis Occurring at Relatively Higher CD4 Counts.

Tugume L, Rhein J, Hullsiek KH, Mpoza E, Kiggundu R, Ssebambulidde K, Schutz C, Taseera K, Williams DA, Abassi M, Muzoora C, Musubire AK, Meintjes G, Meya DB, Boulware DR; COAT and ASTRO-CM teams .

J Infect Dis. 2019 Feb 23;219(6):877-883. doi: 10.1093/infdis/jiy602.

PMID:
30325463
32.

Improving the microbiological diagnosis of tuberculous meningitis: A prospective, international, multicentre comparison of conventional and modified Ziehl-Neelsen stain, GeneXpert, and culture of cerebrospinal fluid.

Heemskerk AD, Donovan J, Thu DDA, Marais S, Chaidir L, Dung VTM, Centner CM, Ha VTN, Annisa J, Dian S, Bovijn L, Mai NTH, Phu NH, Chau NVV, Ganiem AR, Van CT, Geskus RB, Thuong NTT, Ruslami R, Meintjes G, van Crevel R, Wilkinson RJ, Thwaites GE.

J Infect. 2018 Dec;77(6):509-515. doi: 10.1016/j.jinf.2018.09.003. Epub 2018 Sep 12.

33.

EPHA2 sequence variants are associated with susceptibility to Kaposi's sarcoma-associated herpesvirus infection and Kaposi's sarcoma prevalence in HIV-infected patients.

Blumenthal MJ, Schutz C, Meintjes G, Mohamed Z, Mendelson M, Ambler JM, Whitby D, Mackelprang RD, Carse S, Katz AA, Schäfer G.

Cancer Epidemiol. 2018 Oct;56:133-139. doi: 10.1016/j.canep.2018.08.005. Epub 2018 Aug 31.

34.

Improved Treatment Outcomes With Bedaquiline When Substituted for Second-line Injectable Agents in Multidrug-resistant Tuberculosis: A Retrospective Cohort Study.

Zhao Y, Fox T, Manning K, Stewart A, Tiffin N, Khomo N, Leslie J, Boulle A, Mudaly V, Kock Y, Meintjes G, Wasserman S.

Clin Infect Dis. 2019 Apr 24;68(9):1522-1529. doi: 10.1093/cid/ciy727.

35.

Primary antifungal prophylaxis for cryptococcal disease in HIV-positive people.

Awotiwon AA, Johnson S, Rutherford GW, Meintjes G, Eshun-Wilson I.

Cochrane Database Syst Rev. 2018 Aug 29;8:CD004773. doi: 10.1002/14651858.CD004773.pub3.

36.

The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research.

Walker NF, Stek C, Wasserman S, Wilkinson RJ, Meintjes G.

Curr Opin HIV AIDS. 2018 Nov;13(6):512-521. doi: 10.1097/COH.0000000000000502.

37.

Impact of Routine Cryptococcal Antigen Screening and Targeted Preemptive Fluconazole Therapy in Antiretroviral-naive Human Immunodeficiency Virus-infected Adults With CD4 Cell Counts <100/μL: A Systematic Review and Meta-analysis.

Temfack E, Bigna JJ, Luma HN, Spijker R, Meintjes G, Jarvis JN, Dromer F, Harrison T, Cohen JF, Lortholary O.

Clin Infect Dis. 2019 Feb 1;68(4):688-698. doi: 10.1093/cid/ciy567.

38.

Effect of bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study.

Schnippel K, Ndjeka N, Maartens G, Meintjes G, Master I, Ismail N, Hughes J, Ferreira H, Padanilam X, Romero R, Te Riele J, Conradie F.

Lancet Respir Med. 2018 Sep;6(9):699-706. doi: 10.1016/S2213-2600(18)30235-2. Epub 2018 Jul 11.

PMID:
30001994
39.

Contribution of APCs to mucosal-associated invariant T cell activation in infectious disease and cancer.

Shey MS, Balfour A, Wilkinson KA, Meintjes G.

Innate Immun. 2018 May;24(4):192-202. doi: 10.1177/1753425918768695. Epub 2018 Apr 9. Review.

40.

Adult antiretroviral therapy guidelines 2017.

Meintjes G, Moorhouse MA, Carmona S, Davies N, Dlamini S, van Vuuren C, Manzini T, Mathe M, Moosa Y, Nash J, Nel J, Pakade Y, Woods J, Van Zyl G, Conradie F, Venter F.

South Afr J HIV Med. 2017 Jul 15;18(1):776. doi: 10.4102/sajhivmed.v18i1.776. eCollection 2017.

41.

CD4 Cell Count Threshold for Cryptococcal Antigen Screening of HIV-Infected Individuals: A Systematic Review and Meta-analysis.

Ford N, Shubber Z, Jarvis JN, Chiller T, Greene G, Migone C, Vitoria M, Doherty M, Meintjes G.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S152-S159. doi: 10.1093/cid/cix1143.

42.

The Continuing Burden of Advanced HIV Disease Over 10 Years of Increasing Antiretroviral Therapy Coverage in South Africa.

Osler M, Hilderbrand K, Goemaere E, Ford N, Smith M, Meintjes G, Kruger J, Govender NP, Boulle A.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S118-S125. doi: 10.1093/cid/cix1140.

43.

Managing Advanced HIV Disease in a Public Health Approach.

Ford N, Meintjes G, Calmy A, Bygrave H, Migone C, Vitoria M, Penazzato M, Vojnov L, Doherty M; Guideline Development Group for Managing Advanced HIV Disease and Rapid Initiation of Antiretroviral Therapy.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S106-SS110. doi: 10.1093/cid/cix1139.

44.

The Persistent Challenge of Advanced HIV Disease and AIDS in the Era of Antiretroviral Therapy.

Calmy A, Ford N, Meintjes G.

Clin Infect Dis. 2018 Mar 4;66(suppl_2):S103-SS105. doi: 10.1093/cid/cix1138. No abstract available.

45.

Treatment of Tuberculous Meningitis and Its Complications in Adults.

Davis A, Meintjes G, Wilkinson RJ.

Curr Treat Options Neurol. 2018 Feb 28;20(3):5. doi: 10.1007/s11940-018-0490-9. Review.

46.

The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons.

Esmail H, Riou C, Bruyn ED, Lai RP, Harley YXR, Meintjes G, Wilkinson KA, Wilkinson RJ.

Annu Rev Immunol. 2018 Apr 26;36:603-638. doi: 10.1146/annurev-immunol-042617-053420. Epub 2018 Feb 28. Review.

PMID:
29490165
47.

HIV-Associated Mycobacterium tuberculosis Bloodstream Infection Is Underdiagnosed by Single Blood Culture.

Barr DA, Kerkhoff AD, Schutz C, Ward AM, Davies GR, Wilkinson RJ, Meintjes G.

J Clin Microbiol. 2018 Apr 25;56(5). pii: e01914-17. doi: 10.1128/JCM.01914-17. Print 2018 May.

48.

Paradoxical respiratory failure due to cryptococcal pneumonia after amphotericin B treatment for HIV-associated cryptococcal meningitis.

Scriven JE, Botha FC, Schutz C, Lalloo DG, Wainwright H, Meintjes G.

Med Mycol Case Rep. 2018 Jan 17;19:38-40. doi: 10.1016/j.mmcr.2017.02.004. eCollection 2018 Mar.

49.

A Diffuse Fine Papular and Pustular Rash in a Man With Advanced Human Immunodeficiency Virus and Diabetes.

Viljoen C, Dladla K, Francis I, Wainwright H, Meintjes G.

Clin Infect Dis. 2018 Jan 18;66(3):477-478. doi: 10.1093/cid/cix710. No abstract available.

50.

AIDS-Related Endemic Mycoses in Western Cape, South Africa, and Clinical Mimics: A Cross-Sectional Study of Adults With Advanced HIV and Recent-Onset, Widespread Skin Lesions.

Schwartz IS, Kenyon C, Lehloenya R, Claasens S, Spengane Z, Prozesky H, Burton R, Parker A, Wasserman S, Meintjes G, Mendelson M, Taljaard J, Schneider JW, Beylis N, Maloba B, Govender NP, Colebunders R, Dlamini S.

Open Forum Infect Dis. 2017 Aug 25;4(4):ofx186. doi: 10.1093/ofid/ofx186. eCollection 2017 Fall.

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