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Items: 1 to 50 of 123

1.

Complete Genome Sequences of pLMA1 and pLMA7, Two Large Linear Plasmids of Micrococcus Strains Isolated from a High-Altitude Lake in Argentina.

Dib JR, Perez MF, Schuldes J, Poehlein A, Wagenknecht M, Farías ME, Meinhardt F, Daniel R.

Genome Announc. 2018 Feb 22;6(8). pii: e00010-18. doi: 10.1128/genomeA.00010-18.

2.

The restriction modification system of Bacillus licheniformis MS1 and generation of a readily transformable deletion mutant.

Huff F, Muth C, Naumer C, Meinhardt F.

Appl Microbiol Biotechnol. 2017 Nov;101(21):7933-7944. doi: 10.1007/s00253-017-8532-x. Epub 2017 Sep 23.

PMID:
28942561
3.

Genetic evidence for a novel competence inhibitor in the industrially important Bacillus licheniformis.

Muth C, Buchholz M, Schmidt C, Volland S, Meinhardt F.

AMB Express. 2017 Dec;7(1):149. doi: 10.1186/s13568-017-0447-5. Epub 2017 Jul 11.

4.

DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B.

Wemhoff S, Klassen R, Beetz A, Meinhardt F.

PLoS One. 2016 Jul 29;11(7):e0157611. doi: 10.1371/journal.pone.0157611. eCollection 2016.

5.

DNA damage induced by the anticodon nuclease from a Pichia acaciae killer strain is linked to ribonucleotide reductase depletion.

Wemhoff S, Klassen R, Meinhardt F.

Cell Microbiol. 2016 Feb;18(2):211-22. doi: 10.1111/cmi.12496. Epub 2015 Aug 31.

PMID:
26247322
6.

Strategies and approaches in plasmidome studies-uncovering plasmid diversity disregarding of linear elements?

Dib JR, Wagenknecht M, Farías ME, Meinhardt F.

Front Microbiol. 2015 May 26;6:463. doi: 10.3389/fmicb.2015.00463. eCollection 2015. Review.

7.

Complete Genome Sequence of the Linear Plasmid pJD12 Hosted by Micrococcus sp. D12, Isolated from a High-Altitude Volcanic Lake in Argentina.

Dib JR, Angelov A, Liebl W, Döbber J, Voget S, Schuldes J, Gorriti M, Farías ME, Meinhardt F, Daniel R.

Genome Announc. 2015 Jun 11;3(3). pii: e00627-15. doi: 10.1128/genomeA.00627-15.

8.

Autoselection of cytoplasmic yeast virus like elements encoding toxin/antitoxin systems involves a nuclear barrier for immunity gene expression.

Kast A, Voges R, Schroth M, Schaffrath R, Klassen R, Meinhardt F.

PLoS Genet. 2015 May 14;11(5):e1005005. doi: 10.1371/journal.pgen.1005005. eCollection 2015 May.

9.

What renders Bacilli genetically competent? A gaze beyond the model organism.

Jakobs M, Meinhardt F.

Appl Microbiol Biotechnol. 2015 Feb;99(4):1557-70. doi: 10.1007/s00253-014-6316-0. Epub 2014 Dec 31. Review.

PMID:
25547840
10.

The two putative comS homologs of the biotechnologically important Bacillus licheniformis do not contribute to competence development.

Jakobs M, Hoffmann K, Liesegang H, Volland S, Meinhardt F.

Appl Microbiol Biotechnol. 2015 Mar;99(5):2255-66. doi: 10.1007/s00253-014-6291-5. Epub 2014 Dec 19.

PMID:
25520171
11.

Site-directed mutagenesis of the heterotrimeric killer toxin zymocin identifies residues required for early steps in toxin action.

Wemhoff S, Klassen R, Meinhardt F.

Appl Environ Microbiol. 2014 Oct;80(20):6549-59. doi: 10.1128/AEM.02197-14. Epub 2014 Aug 15.

12.

Unravelling the genetic basis for competence development of auxotrophic Bacillus licheniformis 9945A strains.

Jakobs M, Hoffmann K, Grabke A, Neuber S, Liesegang H, Volland S, Meinhardt F.

Microbiology. 2014 Oct;160(Pt 10):2136-47. doi: 10.1099/mic.0.079236-0. Epub 2014 Jul 9.

PMID:
25009236
13.

Immunity factors for two related tRNAGln targeting killer toxins distinguish cognate and non-cognate toxic subunits.

Klassen R, Kast A, Wünsche G, Paluszynski JP, Wemhoff S, Meinhardt F.

Curr Genet. 2014 Aug;60(3):213-22. doi: 10.1007/s00294-014-0426-1. Epub 2014 Apr 10.

PMID:
24719080
14.

Prevalence of obesity and cardiovascular risk among children and adolescents in the municipality of Santa Cruz do Sul, Rio Grande do Sul.

Reuter CP, Burgos LT, Camargo MD, Possuelo LG, Reckziegel MB, Reuter ÉM, Meinhardt FP, Burgos MS.

Sao Paulo Med J. 2013;131(5):323-30. doi: 10.1590/1516-3180.2013.1315518.

15.

rRNA fragmentation induced by a yeast killer toxin.

Kast A, Klassen R, Meinhardt F.

Mol Microbiol. 2014 Feb;91(3):606-17. doi: 10.1111/mmi.12481. Epub 2014 Jan 9.

16.

First complete sequence of a giant linear plasmid from a micrococcus strain isolated from an extremely high-altitude lake.

Dib JR, Schuldes J, Thürmer A, Farias ME, Daniel R, Meinhardt F.

Genome Announc. 2013 Nov 27;1(6). pii: e00885-13. doi: 10.1128/genomeA.00885-13.

17.

Complete Genome Sequence of pAP13, a Large Linear Plasmid of a Brevibacterium Strain Isolated from a Saline Lake at 4,200 Meters above Sea Level in Argentina.

Dib JR, Schuldes J, Thürmer A, Farias ME, Daniel R, Meinhardt F.

Genome Announc. 2013 Nov 27;1(6). pii: e00878-13. doi: 10.1128/genomeA.00878-13.

18.

ALG1-CDG: a new case with early fatal outcome.

Rohlfing AK, Rust S, Reunert J, Tirre M, Du Chesne I, Wemhoff S, Meinhardt F, Hartmann H, Das AM, Marquardt T.

Gene. 2014 Jan 25;534(2):345-51. doi: 10.1016/j.gene.2013.10.013. Epub 2013 Oct 21.

PMID:
24157261
19.

First Insights into the Completely Annotated Genome Sequence of Bacillus licheniformis Strain 9945A.

Rachinger M, Volland S, Meinhardt F, Daniel R, Liesegang H.

Genome Announc. 2013 Aug 1;1(4). pii: e00525-13. doi: 10.1128/genomeA.00525-13.

20.

yneA mRNA instability is involved in temporary inhibition of cell division during the SOS response of Bacillus megaterium.

Buchholz M, Nahrstedt H, Pillukat MH, Deppe V, Meinhardt F.

Microbiology. 2013 Aug;159(Pt 8):1564-74. doi: 10.1099/mic.0.064766-0. Epub 2013 May 31.

PMID:
23728628
21.

Generation of biologically contained, readily transformable, and genetically manageable mutants of the biotechnologically important Bacillus pumilus.

Wemhoff S, Meinhardt F.

Appl Microbiol Biotechnol. 2013 Sep;97(17):7805-19. doi: 10.1007/s00253-013-4935-5. Epub 2013 May 5.

PMID:
23644770
22.

Exoglucanase-encoding genes from three Wickerhamomyces anomalus killer strains isolated from olive brine.

Muccilli S, Wemhoff S, Restuccia C, Meinhardt F.

Yeast. 2013 Jan;30(1):33-43. doi: 10.1002/yea.2935. Epub 2012 Nov 12.

23.

Extrachromosomal genetic elements in Micrococcus.

Dib JR, Liebl W, Wagenknecht M, Farías ME, Meinhardt F.

Appl Microbiol Biotechnol. 2013 Jan;97(1):63-75. doi: 10.1007/s00253-012-4539-5. Epub 2012 Nov 9. Review.

PMID:
23138713
24.

Anticodon nuclease encoding virus-like elements in yeast.

Satwika D, Klassen R, Meinhardt F.

Appl Microbiol Biotechnol. 2012 Oct;96(2):345-56. doi: 10.1007/s00253-012-4349-9. Epub 2012 Aug 17. Review.

PMID:
22899498
25.

A fungal anticodon nuclease ribotoxin exploits a secondary cleavage site to evade tRNA repair.

Meineke B, Kast A, Schwer B, Meinhardt F, Shuman S, Klassen R.

RNA. 2012 Sep;18(9):1716-24. doi: 10.1261/rna.034132.112. Epub 2012 Jul 26.

26.

Repeated capture of a cytoplasmic linear plasmid by the host nucleus in Debaryomyces hansenii.

Satwika D, Klassen R, Meinhardt F.

Yeast. 2012 Mar;29(3-4):145-54. doi: 10.1002/yea.2893. Epub 2012 Mar 21.

27.

Genetic analysis of the Bacillus licheniformis degSU operon and the impact of regulatory mutations on protease production.

Borgmeier C, Bongaerts J, Meinhardt F.

J Biotechnol. 2012 May 31;159(1-2):12-20. doi: 10.1016/j.jbiotec.2012.02.011. Epub 2012 Feb 25.

PMID:
22387916
28.

Systems biology of recombinant protein production using Bacillus megaterium.

Biedendieck R, Borgmeier C, Bunk B, Stammen S, Scherling C, Meinhardt F, Wittmann C, Jahn D.

Methods Enzymol. 2011;500:165-95. doi: 10.1016/B978-0-12-385118-5.00010-4.

PMID:
21943898
29.

Transcriptome profiling of degU expression reveals unexpected regulatory patterns in Bacillus megaterium and discloses new targets for optimizing expression.

Borgmeier C, Biedendieck R, Hoffmann K, Jahn D, Meinhardt F.

Appl Microbiol Biotechnol. 2011 Nov;92(3):583-96. doi: 10.1007/s00253-011-3575-x. Epub 2011 Sep 21. Erratum in: Appl Microbiol Biotechnol. 2011 Dec;92(6):1315-6.

PMID:
21935588
30.

Functional analysis of the response regulator DegU in Bacillus megaterium DSM319 and comparative secretome analysis of degSU mutants.

Borgmeier C, Voigt B, Hecker M, Meinhardt F.

Appl Microbiol Biotechnol. 2011 Aug;91(3):699-711. doi: 10.1007/s00253-011-3302-7. Epub 2011 May 3.

PMID:
21538108
31.

Genetic control of amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR.

Deppe VM, Klatte S, Bongaerts J, Maurer KH, O'Connell T, Meinhardt F.

Appl Environ Microbiol. 2011 May;77(9):2839-46. doi: 10.1128/AEM.02515-10. Epub 2011 Mar 11.

32.

Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions.

Deppe VM, Bongaerts J, O'Connell T, Maurer KH, Meinhardt F.

Appl Microbiol Biotechnol. 2011 Apr;90(2):399-406. doi: 10.1007/s00253-010-3083-4. Epub 2011 Feb 24. Review.

PMID:
21347729
33.

DNA repair defects sensitize cells to anticodon nuclease yeast killer toxins.

Klassen R, Wemhoff S, Krause J, Meinhardt F.

Mol Genet Genomics. 2011 Mar;285(3):185-95. doi: 10.1007/s00438-010-0597-5. Epub 2010 Dec 28.

PMID:
21188417
34.

Replication-involved genes of pAL1, the linear plasmid of Arthrobacter nitroguajacolicus Rü61a--phylogenetic and transcriptional analysis.

Wagenknecht M, Meinhardt F.

Plasmid. 2011 Mar;65(2):176-84. doi: 10.1016/j.plasmid.2010.12.005. Epub 2010 Dec 24.

PMID:
21185858
35.

Genetic improvement of Bacillus licheniformis strains for efficient deproteinization of shrimp shells and production of high-molecular-mass chitin and chitosan.

Hoffmann K, Daum G, Köster M, Kulicke WM, Meyer-Rammes H, Bisping B, Meinhardt F.

Appl Environ Microbiol. 2010 Dec;76(24):8211-21. doi: 10.1128/AEM.01404-10. Epub 2010 Oct 22.

36.

Structural peculiarities of linear megaplasmid, pLMA1, from Micrococcus luteus interfere with pyrosequencing reads assembly.

Wagenknecht M, Dib JR, Thürmer A, Daniel R, Farías ME, Meinhardt F.

Biotechnol Lett. 2010 Dec;32(12):1853-62. doi: 10.1007/s10529-010-0357-y. Epub 2010 Jul 21.

37.

Facilitation of direct conditional knockout of essential genes in Bacillus licheniformis DSM13 by comparative genetic analysis and manipulation of genetic competence.

Hoffmann K, Wollherr A, Larsen M, Rachinger M, Liesegang H, Ehrenreich A, Meinhardt F.

Appl Environ Microbiol. 2010 Aug;76(15):5046-57. doi: 10.1128/AEM.00660-10. Epub 2010 Jun 11.

38.

Novel linear megaplasmid from Brevibacterium sp. isolated from extreme environment.

Dib JR, Wagenknecht M, Hill RT, Farías ME, Meinhardt F.

J Basic Microbiol. 2010 Jun;50(3):280-4. doi: 10.1002/jobm.200900332.

PMID:
20473959
39.

An improved transconjugation protocol for Bacillus megaterium facilitating a direct genetic knockout.

Richhardt J, Larsen M, Meinhardt F.

Appl Microbiol Biotechnol. 2010 May;86(6):1959-65. doi: 10.1007/s00253-010-2503-9. Epub 2010 Mar 10.

PMID:
20217076
40.
41.

First report of linear megaplasmids in the genus Micrococcus.

Dib JR, Wagenknecht M, Hill RT, Farías ME, Meinhardt F.

Plasmid. 2010 Jan;63(1):40-5. doi: 10.1016/j.plasmid.2009.10.001. Epub 2009 Oct 19.

PMID:
19850076
42.

Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast.

Paluszynski JP, Klassen R, Meinhardt F.

Microbiology. 2008 Oct;154(Pt 10):3154-64. doi: 10.1099/mic.0.2008/020107-0.

PMID:
18832321
43.

The primary target of the killer toxin from Pichia acaciae is tRNA(Gln).

Klassen R, Paluszynski JP, Wemhoff S, Pfeiffer A, Fricke J, Meinhardt F.

Mol Microbiol. 2008 Aug;69(3):681-97. doi: 10.1111/j.1365-2958.2008.06319.x. Epub 2008 Jun 28.

44.

A modified DNA isolation protocol for obtaining pure RT-PCR grade RNA.

Klassen R, Fricke J, Pfeiffer A, Meinhardt F.

Biotechnol Lett. 2008 Jun;30(6):1041-4. doi: 10.1007/s10529-008-9648-y. Epub 2008 Feb 2.

PMID:
18246302
45.

Generation of readily transformable Bacillus licheniformis mutants.

Waschkau B, Waldeck J, Wieland S, Eichstädt R, Meinhardt F.

Appl Microbiol Biotechnol. 2008 Feb;78(1):181-8. Epub 2007 Nov 29.

PMID:
18046550
46.

Radiocarbon observations in atmospheric CO2: determining fossil fuel CO2 over Europe using Jungfraujoch observations as background.

Levin I, Hammer S, Kromer B, Meinhardt F.

Sci Total Environ. 2008 Mar 1;391(2-3):211-6. Epub 2007 Nov 26.

PMID:
18037473
47.

Homologous recombination and the yKu70/80 complex exert opposite roles in resistance against the killer toxin from Pichia acaciae.

Klassen R, Krampe S, Meinhardt F.

DNA Repair (Amst). 2007 Dec 1;6(12):1864-75. Epub 2007 Aug 30.

PMID:
17765020
48.

Bacillus megaterium--from simple soil bacterium to industrial protein production host.

Vary PS, Biedendieck R, Fuerch T, Meinhardt F, Rohde M, Deckwer WD, Jahn D.

Appl Microbiol Biotechnol. 2007 Oct;76(5):957-67. Epub 2007 Jul 26. Review.

PMID:
17657486
49.

Pichia acaciae killer system: genetic analysis of toxin immunity.

Paluszynski JP, Klassen R, Meinhardt F.

Appl Environ Microbiol. 2007 Jul;73(13):4373-8. Epub 2007 May 4.

50.

Targeted deletion of genes encoding extracellular enzymes in Bacillus licheniformis and the impact on the secretion capability.

Waldeck J, Meyer-Rammes H, Wieland S, Feesche J, Maurer KH, Meinhardt F.

J Biotechnol. 2007 Jun 15;130(2):124-32. Epub 2007 Mar 31.

PMID:
17481763

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