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Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice.

Bakker ER, Raghoebir L, Franken PF, Helvensteijn W, van Gurp L, Meijlink F, van der Valk MA, Rottier RJ, Kuipers EJ, van Veelen W, Smits R.

Dev Biol. 2012 Sep 1;369(1):91-100. doi: 10.1016/j.ydbio.2012.06.007. Epub 2012 Jun 9.


Concerted involvement of Cdx/Hox genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone.

van de Ven C, Bialecka M, Neijts R, Young T, Rowland JE, Stringer EJ, Van Rooijen C, Meijlink F, Nóvoa A, Freund JN, Mallo M, Beck F, Deschamps J.

Development. 2011 Aug;138(16):3451-62. doi: 10.1242/dev.066118. Epub 2011 Jul 13. Erratum in: Development. 2011 Sep 1;138(17):3859.


An ENU-mutagenesis screen in the mouse: identification of novel developmental gene functions.

Wansleeben C, van Gurp L, Feitsma H, Kroon C, Rieter E, Verberne M, Guryev V, Cuppen E, Meijlink F.

PLoS One. 2011 Apr 29;6(4):e19357. doi: 10.1371/journal.pone.0019357.


An ENU-induced point mutation in the mouse Btaf1 gene causes post-gastrulation embryonic lethality and protein instability.

Wansleeben C, van Gurp L, de Graaf P, Mousson F, Marc Timmers HT, Meijlink F.

Mech Dev. 2011 May-Jun;128(5-6):279-88. doi: 10.1016/j.mod.2011.03.002. Epub 2011 Mar 16.


β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis.

van Veelen W, Le NH, Helvensteijn W, Blonden L, Theeuwes M, Bakker ER, Franken PF, van Gurp L, Meijlink F, van der Valk MA, Kuipers EJ, Fodde R, Smits R.

Gut. 2011 Sep;60(9):1204-12. doi: 10.1136/gut.2010.233460. Epub 2011 Feb 9.


The planar cell polarity pathway in vertebrate development.

Wansleeben C, Meijlink F.

Dev Dyn. 2011 Mar;240(3):616-26. doi: 10.1002/dvdy.22564. Epub 2011 Feb 8. Review.


A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction.

Wansleeben C, Feitsma H, Tertoolen L, Kroon C, Guryev V, Cuppen E, Meijlink F.

Int J Dev Biol. 2010;54(10):1465-71. doi: 10.1387/ijdb.093051cw.


Genetic analysis of Hedgehog signaling in ventral body wall development and the onset of omphalocele formation.

Matsumaru D, Haraguchi R, Miyagawa S, Motoyama J, Nakagata N, Meijlink F, Yamada G.

PLoS One. 2011 Jan 20;6(1):e16260. doi: 10.1371/journal.pone.0016260.


Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.

Wansleeben C, Feitsma H, Montcouquiol M, Kroon C, Cuppen E, Meijlink F.

Development. 2010 Apr;137(7):1067-73. doi: 10.1242/dev.041434.


Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.

Blaschke RJ, Hahurij ND, Kuijper S, Just S, Wisse LJ, Deissler K, Maxelon T, Anastassiadis K, Spitzer J, Hardt SE, Schöler H, Feitsma H, Rottbauer W, Blum M, Meijlink F, Rappold G, Gittenberger-de Groot AC.

Circulation. 2007 Apr 10;115(14):1830-8. Epub 2007 Mar 19.


1 Patterning the limb before and after SHH.

Te Welscher P, Zuniga A, Fernandez-Teran M, Ros M, Kuijper S, Drenth T, Goedemans H, Meijlink F, Zeller R.

J Anat. 2002 Nov;201(5):417.


Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh.

Kuijper S, Feitsma H, Sheth R, Korving J, Reijnen M, Meijlink F.

Dev Biol. 2005 Sep 15;285(2):533-44. Epub 2005 Jul 21.


Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes.

Kuijper S, Beverdam A, Kroon C, Brouwer A, Candille S, Barsh G, Meijlink F.

Development. 2005 Apr;132(7):1601-10. Epub 2005 Feb 23.


Expression of retinaldehyde dehydrogenase II and sequential activation of 5' Hoxb genes in the mouse caudal hindbrain.

Oosterveen T, Meijlink F, Deschamps J.

Gene Expr Patterns. 2004 May;4(3):243-7.


Dorsoventral patterning of the mouse coat by Tbx15.

Candille SI, Van Raamsdonk CD, Chen C, Kuijper S, Chen-Tsai Y, Russ A, Meijlink F, Barsh GS.

PLoS Biol. 2004 Jan;2(1):E3. Epub 2004 Jan 20.


The direct context of a hox retinoic acid response element is crucial for its activity.

Oosterveen T, van Vliet P, Deschamps J, Meijlink F.

J Biol Chem. 2003 Jun 27;278(26):24103-7. Epub 2003 Apr 15.


The OAR/aristaless domain of the homeodomain protein Cart1 has an attenuating role in vivo.

Brouwer A, ten Berge D, Wiegerinck R, Meijlink F.

Mech Dev. 2003 Feb;120(2):241-52.


Deletion of the homeobox gene PRX-2 affects fetal but not adult fibroblast wound healing responses.

White P, Thomas DW, Fong S, Stelnicki E, Meijlink F, Largman C, Stephens P.

J Invest Dermatol. 2003 Jan;120(1):135-44.


Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain.

Oosterveen T, Niederreither K, Dollé P, Chambon P, Meijlink F, Deschamps J.

EMBO J. 2003 Jan 15;22(2):262-9.


Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, Meijlink F, Zeller R.

Science. 2002 Oct 25;298(5594):827-30. Epub 2002 Sep 5.


Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice.

Beverdam A, Brouwer A, Reijnen M, Korving J, Meijlink F.

Development. 2001 Oct;128(20):3975-86.


Automated topographical cell proliferation analysis.

van Raaij EJ, ten Berge D, Hage W, Brouwer A, Meijlink F, Maintz JB, Verbeek FJ.

Cytometry. 2001 Sep 1;45(1):13-8.


Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis.

ten Berge D, Brouwer A, Korving J, Reijnen MJ, van Raaij EJ, Verbeek F, Gaffield W, Meijlink F.

Development. 2001 Aug;128(15):2929-38.


Vertebrate aristaless-related genes.

Meijlink F, Beverdam A, Brouwer A, Oosterveen TC, Berge DT.

Int J Dev Biol. 1999;43(7):651-63. Review.


Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes.

van den Akker E, Reijnen M, Korving J, Brouwer A, Meijlink F, Deschamps J.

Mech Dev. 1999 Dec;89(1-2):103-14.


Patterns of paired-related homeobox genes PRX1 and PRX2 suggest involvement in matrix modulation in the developing chick vascular system.

Bergwerff M, Gittenberger-de Groot AC, DeRuiter MC, van Iperen L, Meijlink F, Poelmann RE.

Dev Dyn. 1998 Sep;213(1):59-70.


Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.

ten Berge D, Brouwer A, Korving J, Martin JF, Meijlink F.

Development. 1998 Oct;125(19):3831-42.


Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm.

ten Berge D, Brouwer A, el Bahi S, Guénet JL, Robert B, Meijlink F.

Dev Biol. 1998 Jul 1;199(1):11-25.


Regulation of the Hoxb-8 gene: synergism between multimerized cis-acting elements increases responsiveness to positional information.

Charité J, de Graaff W, Vogels R, Meijlink F, Deschamps J.

Dev Biol. 1995 Oct;171(2):294-305.


Expression patterns of the paired-related homeobox genes MHox/Prx1 and S8/Prx2 suggest roles in development of the heart and the forebrain.

Leussink B, Brouwer A, el Khattabi M, Poelmann RE, Gittenberger-de Groot AC, Meijlink F.

Mech Dev. 1995 Jul;52(1):51-64.


DNA-binding specificity of the S8 homeodomain.

de Jong R, van der Heijden J, Meijlink F.

Nucleic Acids Res. 1993 Oct 11;21(20):4711-20.


Differential expression of the HMG box factors TCF-1 and LEF-1 during murine embryogenesis.

Oosterwegel M, van de Wetering M, Timmerman J, Kruisbeek A, Destree O, Meijlink F, Clevers H.

Development. 1993 Jun;118(2):439-48.


Induction of HOX-2 genes in P19 embryocarcinoma cells is dependent on retinoic acid receptor alpha.

Zwartkruis F, Kruyt F, van der Saag PT, Meijlink F.

Exp Cell Res. 1993 Apr;205(2):422-5.


DNA-binding activity of the murine homeodomain protein Hox-2.3 produced by a hybrid phage T7/vaccinia virus system.

de Jong R, de Laaf L, Vennema H, Meijlink F.

Gene. 1992 Jul 15;116(2):195-203.


The murine Hox-2.4 promoter contains a functional octamer motif.

Zwartkruis F, Hoeijmakers T, Deschamps J, Meijlink F.

Nucleic Acids Res. 1992 Apr 11;20(7):1599-606.


Mammalian homeobox genes in normal development and neoplasia.

Deschamps J, Meijlink F.

Crit Rev Oncog. 1992;3(1-2):117-73. Review.


Cloning of murine TCF-1, a T cell-specific transcription factor interacting with functional motifs in the CD3-epsilon and T cell receptor alpha enhancers.

Oosterwegel M, van de Wetering M, Dooijes D, Klomp L, Winoto A, Georgopoulos K, Meijlink F, Clevers H.

J Exp Med. 1991 May 1;173(5):1133-42.


The mouse homeobox gene, S8, is expressed during embryogenesis predominantly in mesenchyme.

Opstelten DJ, Vogels R, Robert B, Kalkhoven E, Zwartkruis F, de Laaf L, Destrée OH, Deschamps J, Lawson KA, Meijlink F.

Mech Dev. 1991 Mar;34(1):29-41.


Characterization of the murine Hox-2.3 promoter: involvement of the transcription factor USF (MLTF).

Zwartkruis F, Hoeijmakers T, Deschamps J, Meijlink F.

Mech Dev. 1991 Mar;33(3):179-90.


Hox-2.3 upstream sequences mediate lacZ expression in intermediate mesoderm derivatives of transgenic mice.

Kress C, Vogels R, De Graaff W, Bonnerot C, Meijlink F, Nicolas JF, Deschamps J.

Development. 1990 Aug;109(4):775-86.


Isolation of the Xenopus homolog of int-1/wingless and expression during neurula stages of early development.

Noordermeer J, Meijlink F, Verrijzer P, Rijsewijk F, Destrée O.

Nucleic Acids Res. 1989 Jan 11;17(1):11-8.


Nucleotide sequence of the Hox2.3 gene region.

Verrijzer P, de Graaff W, Deschamps J, Meijlink F.

Nucleic Acids Res. 1988 Mar 25;16(6):2729. No abstract available.


A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression.

Meijlink F, de Laaf R, Verrijzer P, Destrée O, Kroezen V, Hilkens J, Deschamps J.

Nucleic Acids Res. 1987 Sep 11;15(17):6773-86.


A new repetitive element of the CR1 family downstream of the chicken vitellogenin gene.

van het Schip F, Samallo J, Meijlink F, Gruber M, AB G.

Nucleic Acids Res. 1987 May 26;15(10):4193-202.


Abundant expression of homeobox genes in mouse embryonal carcinoma cells correlates with chemically induced differentiation.

Deschamps J, de Laaf R, Joosen L, Meijlink F, Destrée O.

Proc Natl Acad Sci U S A. 1987 Mar;84(5):1304-8.


The mouse Hox2.3 homeobox-containing gene: regulation in differentiating pluripotent stem cells and expression pattern in embryos.

Deschamps J, de Laaf R, Verrijzer P, de Gouw M, Destrée O, Meijlink F.

Differentiation. 1987;35(1):21-30.


Identification of a transcriptional enhancer element upstream from the proto-oncogene fos.

Deschamps J, Meijlink F, Verma IM.

Science. 1985 Dec 6;230(4730):1174-7.


Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene.

Meijlink F, Curran T, Miller AD, Verma IM.

Proc Natl Acad Sci U S A. 1985 Aug;82(15):4987-91.

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