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Items: 1 to 50 of 68

1.

Proteome-wide mapping of PQS-interacting proteins in Pseudomonas aeruginosa.

Dandela R, Mantin D, Cravatt BF, Rayo J, Meijler MM.

Chem Sci. 2018 Jan 19;9(8):2290-2294. doi: 10.1039/c7sc04287f. eCollection 2018 Feb 28.

2.

Reciprocal Interactions between Membrane Bilayers and S. aureus PSMα3 Cross-α Amyloid Fibrils Account for Species-Specific Cytotoxicity.

Malishev R, Tayeb-Fligelman E, David S, Meijler MM, Landau M, Jelinek R.

J Mol Biol. 2018 May 11;430(10):1431-1441. doi: 10.1016/j.jmb.2018.03.022. Epub 2018 Apr 3.

PMID:
29625200
3.

Electron transfer rate analysis of a site-specifically wired copper oxidase.

Schlesinger O, Pasi M, Dandela R, Meijler MM, Alfonta L.

Phys Chem Chem Phys. 2018 Feb 28;20(9):6159-6166. doi: 10.1039/c8cp00041g.

PMID:
29457817
4.

Photo-switchable microbial fuel-cells.

Schlesinger O, Dandela R, Bhagat A, Adepu R, Meijler MM, Xia L, Alfonta L.

Biotechnol Bioeng. 2018 May;115(5):1355-1360. doi: 10.1002/bit.26555. Epub 2018 Feb 26.

PMID:
29411858
5.

Chemical strategies to unravel bacterial-eukaryotic signaling.

Gregor R, David S, Meijler MM.

Chem Soc Rev. 2018 Mar 5;47(5):1761-1772. doi: 10.1039/c7cs00606c. Review.

PMID:
29260158
6.

Mining Plants for Bacterial Quorum Sensing Modulators.

David S, Mandabi A, Uzi S, Aharoni A, Meijler MM.

ACS Chem Biol. 2018 Jan 19;13(1):247-252. doi: 10.1021/acschembio.7b00859. Epub 2017 Dec 27.

PMID:
29215859
7.

Quorum sensing modulators exhibit cytotoxicity in Hodgkin's lymphoma cells and interfere with NF-κB signaling.

Nandakumar N, Dandela R, Gopas J, Meijler MM.

Bioorg Med Chem Lett. 2017 Jul 1;27(13):2967-2973. doi: 10.1016/j.bmcl.2017.05.012. Epub 2017 May 6.

PMID:
28526369
8.

The regulatory significance of tag recycling in the mycobacterial Pup-proteasome system.

Elharar Y, Schlussel S, Hecht N, Meijler MM, Gur E.

FEBS J. 2017 Jun;284(12):1804-1814. doi: 10.1111/febs.14086. Epub 2017 May 18.

9.

Synthesis and evaluation of a tag-free photoactive phospho-ceramide analogue-1 (PCERA-1) probe to study immunomodulation in macrophages.

Dandela R, Mashiach R, Adepu R, Gregor R, Athamna M, Zecharia E, Ernst O, Zor T, Meijler MM.

Chem Commun (Camb). 2017 Mar 30;53(27):3842-3845. doi: 10.1039/c6cc09849e.

PMID:
28317057
10.

Understanding the Collective Nose of Bacteria.

Meijler MM.

Cell Chem Biol. 2016 Mar 17;23(3):317-8. doi: 10.1016/j.chembiol.2016.03.005.

11.

Imaging Pseudomonas aeruginosa Biofilm Extracellular Polymer Scaffolds with Amphiphilic Carbon Dots.

Ritenberg M, Nandi S, Kolusheva S, Dandela R, Meijler MM, Jelinek R.

ACS Chem Biol. 2016 May 20;11(5):1265-70. doi: 10.1021/acschembio.5b01000. Epub 2016 Feb 26.

PMID:
26882175
12.

Fine-Tuning Covalent Inhibition of Bacterial Quorum Sensing.

Amara N, Gregor R, Rayo J, Dandela R, Daniel E, Liubin N, Willems HM, Ben-Zvi A, Krom BP, Meijler MM.

Chembiochem. 2016 May 3;17(9):825-35. doi: 10.1002/cbic.201500676. Epub 2016 Mar 15.

PMID:
26840534
13.

Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors.

Katz S, Ernst O, Avni D, Athamna M, Philosoph A, Arana L, Ouro A, Hoeferlin LA, Meijler MM, Chalfant CE, Gómez-Muñoz A, Zor T.

Immunol Lett. 2016 Jan;169:73-81. doi: 10.1016/j.imlet.2015.12.001. Epub 2015 Dec 3.

14.

Synergistic activation of quorum sensing in Vibrio harveyi.

Mandabi A, Ganin H, Meijler MM.

Bioorg Med Chem Lett. 2015 Sep 15;25(18):3966-9. doi: 10.1016/j.bmcl.2015.07.028. Epub 2015 Jul 17.

PMID:
26248803
15.

Building up a chemical proteomics network in Europe and beyond.

Köhn M, Meijler MM, Kaiser M.

ACS Chem Biol. 2014 Aug 15;9(8):1647-8. doi: 10.1021/cb5005299. No abstract available.

PMID:
25123303
16.

AI-2 of Aggregatibacter actinomycetemcomitans inhibits Candida albicans biofilm formation.

Bachtiar EW, Bachtiar BM, Jarosz LM, Amir LR, Sunarto H, Ganin H, Meijler MM, Krom BP.

Front Cell Infect Microbiol. 2014 Jul 21;4:94. doi: 10.3389/fcimb.2014.00094. eCollection 2014.

17.

Karrikins from plant smoke modulate bacterial quorum sensing.

Mandabi A, Ganin H, Krief P, Rayo J, Meijler MM.

Chem Commun (Camb). 2014 May 25;50(40):5322-5. doi: 10.1039/c3cc47501h. Epub 2013 Dec 10.

PMID:
24327106
18.

Tailor-made LasR agonists modulate quorum sensing in Pseudomonas aeruginosa.

Rabin N, Delago A, Inbal B, Krief P, Meijler MM.

Org Biomol Chem. 2013 Nov 7;11(41):7155-63. doi: 10.1039/c3ob41377b.

PMID:
24057196
19.

Polymerase I pathway inhibitor ameliorates experimental autoimmune encephalomyelitis.

Achiron A, Mashiach R, Zilkha-Falb R, Meijler MM, Gurevich M.

J Neuroimmunol. 2013 Oct 15;263(1-2):91-7. doi: 10.1016/j.jneuroim.2013.08.002. Epub 2013 Aug 15.

PMID:
23998422
20.

The bacterial quorum-sensing signal molecule N-3-oxo-dodecanoyl-L-homoserine lactone reciprocally modulates pro- and anti-inflammatory cytokines in activated macrophages.

Glucksam-Galnoy Y, Sananes R, Silberstein N, Krief P, Kravchenko VV, Meijler MM, Zor T.

J Immunol. 2013 Jul 1;191(1):337-44. doi: 10.4049/jimmunol.1300368. Epub 2013 May 29.

21.

Species selective diazirine positioning in tag-free photoactive quorum sensing probes.

Dubinsky L, Delago A, Amara N, Krief P, Rayo J, Zor T, Kravchenko VV, Meijler MM.

Chem Commun (Camb). 2013 Jul 4;49(52):5826-8. doi: 10.1039/c3cc43092h. Epub 2013 May 24.

22.

Multivalent alteration of quorum sensing in Staphylococcus aureus.

Melamed Yerushalmi S, Buck ME, Lynn DM, Lemcoff NG, Meijler MM.

Chem Commun (Camb). 2013 Jun 7;49(45):5177-9. doi: 10.1039/c3cc41645c.

PMID:
23628938
23.

Total synthesis of pyoverdin D.

Mashiach R, Meijler MM.

Org Lett. 2013 Apr 5;15(7):1702-5. doi: 10.1021/ol400490s. Epub 2013 Mar 26.

PMID:
23530778
24.

Surface display of a redox enzyme and its site-specific wiring to gold electrodes.

Amir L, Carnally SA, Rayo J, Rosenne S, Melamed Yerushalmi S, Schlesinger O, Meijler MM, Alfonta L.

J Am Chem Soc. 2013 Jan 9;135(1):70-3. doi: 10.1021/ja310556n. Epub 2012 Dec 18.

PMID:
23231821
25.

MUNC13-4 protein regulates the oxidative response and is essential for phagosomal maturation and bacterial killing in neutrophils.

Monfregola J, Johnson JL, Meijler MM, Napolitano G, Catz SD.

J Biol Chem. 2012 Dec 28;287(53):44603-18. doi: 10.1074/jbc.M112.414029. Epub 2012 Oct 31.

26.

Vibrio cholerae autoinducer CAI-1 interferes with Pseudomonas aeruginosa quorum sensing and inhibits its growth.

Ganin H, Danin-Poleg Y, Kashi Y, Meijler MM.

ACS Chem Biol. 2012 Apr 20;7(4):659-65. doi: 10.1021/cb2004675. Epub 2012 Feb 1.

PMID:
22270383
27.

The transition of human estrogen sulfotransferase from generalist to specialist using directed enzyme evolution.

Amar D, Berger I, Amara N, Tafa G, Meijler MM, Aharoni A.

J Mol Biol. 2012 Feb 10;416(1):21-32. doi: 10.1016/j.jmb.2011.12.013. Epub 2011 Dec 13.

PMID:
22197379
28.

Microbial spy games and host response: roles of a Pseudomonas aeruginosa small molecule in communication with other species.

Jarosz LM, Ovchinnikova ES, Meijler MM, Krom BP.

PLoS Pathog. 2011 Nov;7(11):e1002312. doi: 10.1371/journal.ppat.1002312. Epub 2011 Nov 17. No abstract available.

29.

Diazirine based photoaffinity labeling.

Dubinsky L, Krom BP, Meijler MM.

Bioorg Med Chem. 2012 Jan 15;20(2):554-70. doi: 10.1016/j.bmc.2011.06.066. Epub 2011 Jun 29. Review.

PMID:
21778062
30.

Live cell labeling of native intracellular bacterial receptors using aniline-catalyzed oxime ligation.

Rayo J, Amara N, Krief P, Meijler MM.

J Am Chem Soc. 2011 May 18;133(19):7469-75. doi: 10.1021/ja200455d. Epub 2011 Apr 22.

PMID:
21513325
31.

Macromolecular inhibition of quorum sensing: enzymes, antibodies, and beyond.

Amara N, Krom BP, Kaufmann GF, Meijler MM.

Chem Rev. 2011 Jan 12;111(1):195-208. doi: 10.1021/cr100101c. Epub 2010 Nov 18. Review. No abstract available.

PMID:
21087050
32.

A ceramide analog inhibits cPLA(2) activity and consequent PGE(2) formation in LPS-stimulated macrophages.

Goldsmith M, Daka A, Lamour NF, Mashiach R, Glucksam Y, Meijler MM, Chalfant CE, Zor T.

Immunol Lett. 2011 Mar 30;135(1-2):136-43. doi: 10.1016/j.imlet.2010.10.014. Epub 2010 Oct 30.

33.

Synthesis and validation of a probe to identify quorum sensing receptors.

Dubinsky L, Jarosz LM, Amara N, Krief P, Kravchenko VV, Krom BP, Meijler MM.

Chem Commun (Camb). 2009 Dec 21;(47):7378-80. doi: 10.1039/b917507e. Epub 2009 Oct 28.

PMID:
20024234
34.

The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner.

Avni D, Philosoph A, Meijler MM, Zor T.

Immunology. 2010 Mar;129(3):375-85. doi: 10.1111/j.1365-2567.2009.03188.x. Epub 2009 Nov 16.

35.

Defining the mode of action of tetramic acid antibacterials derived from Pseudomonas aeruginosa quorum sensing signals.

Lowery CA, Park J, Gloeckner C, Meijler MM, Mueller RS, Boshoff HI, Ulrich RL, Barry CE 3rd, Bartlett DH, Kravchenko VV, Kaufmann GF, Janda KD.

J Am Chem Soc. 2009 Oct 14;131(40):14473-9. doi: 10.1021/ja9056079.

36.

Covalent inhibition of bacterial quorum sensing.

Amara N, Mashiach R, Amar D, Krief P, Spieser SA, Bottomley MJ, Aharoni A, Meijler MM.

J Am Chem Soc. 2009 Aug 5;131(30):10610-9. doi: 10.1021/ja903292v.

PMID:
19585989
37.

Distinct receptor-mediated activities in macrophages for natural ceramide-1-phosphate (C1P) and for phospho-ceramide analogue-1 (PCERA-1).

Levi M, Meijler MM, Gómez-Muñoz A, Zor T.

Mol Cell Endocrinol. 2010 Jan 27;314(2):248-55. doi: 10.1016/j.mce.2009.05.007. Epub 2009 May 23. Review.

PMID:
19467294
38.

Electrochemical analysis of quorum sensing inhibition.

Bukelman O, Amara N, Mashiach R, Krief P, Meijler MM, Alfonta L.

Chem Commun (Camb). 2009 May 28;(20):2836-8. doi: 10.1039/b901125k. Epub 2009 Mar 9.

PMID:
19436882
39.

Inhibition of Pseudomonas aeruginosa quorum sensing by AI-2 analogs.

Ganin H, Tang X, Meijler MM.

Bioorg Med Chem Lett. 2009 Jul 15;19(14):3941-4. doi: 10.1016/j.bmcl.2009.03.163. Epub 2009 Apr 9.

PMID:
19394822
40.

Synergistic IL-10 induction by LPS and the ceramide-1-phosphate analog PCERA-1 is mediated by the cAMP and p38 MAP kinase pathways.

Goldsmith M, Avni D, Ernst O, Glucksam Y, Levy-Rimler G, Meijler MM, Zor T.

Mol Immunol. 2009 Jun;46(10):1979-87. doi: 10.1016/j.molimm.2009.03.009. Epub 2009 Apr 10.

PMID:
19362373
41.

Modulation of TNFalpha, IL-10 and IL-12p40 levels by a ceramide-1-phosphate analog, PCERA-1, in vivo and ex vivo in primary macrophages.

Avni D, Goldsmith M, Ernst O, Mashiach R, Tuntland T, Meijler MM, Gray NS, Rosen H, Zor T.

Immunol Lett. 2009 Mar 24;123(1):1-8. doi: 10.1016/j.imlet.2008.12.011. Epub 2009 Jan 29.

PMID:
19185589
42.

Biofuel cell controlled by enzyme logic systems.

Amir L, Tam TK, Pita M, Meijler MM, Alfonta L, Katz E.

J Am Chem Soc. 2009 Jan 21;131(2):826-32. doi: 10.1021/ja8076704.

PMID:
19105750
43.

Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice.

Mayorov AV, Amara N, Chang JY, Moss JA, Hixon MS, Ruiz DI, Meijler MM, Zorrilla EP, Janda KD.

Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17487-92. doi: 10.1073/pnas.0711808105. Epub 2008 Nov 3.

44.

A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages.

Goldsmith M, Avni D, Levy-Rimler G, Mashiach R, Ernst O, Levi M, Webb B, Meijler MM, Gray NS, Rosen H, Zor T.

Immunology. 2009 May;127(1):103-15. doi: 10.1111/j.1365-2567.2008.02928.x.

45.

Modulation of gene expression via disruption of NF-kappaB signaling by a bacterial small molecule.

Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Grauer DC, Lehmann M, Meijler MM, Janda KD, Ulevitch RJ.

Science. 2008 Jul 11;321(5886):259-63. doi: 10.1126/science.1156499. Epub 2008 Jun 19.

46.

Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.

Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA.

Science. 2008 Feb 29;319(5867):1232-5. doi: 10.1126/science.1153445.

47.

Infection control by antibody disruption of bacterial quorum sensing signaling.

Park J, Jagasia R, Kaufmann GF, Mathison JC, Ruiz DI, Moss JA, Meijler MM, Ulevitch RJ, Janda KD.

Chem Biol. 2007 Oct;14(10):1119-27.

48.

Antibody catalyzed hydrolysis of a quorum sensing signal found in Gram-negative bacteria.

De Lamo Marin S, Xu Y, Meijler MM, Janda KD.

Bioorg Med Chem Lett. 2007 Mar 15;17(6):1549-52. Epub 2007 Jan 13.

PMID:
17254784
49.

N-(3-oxo-acyl)homoserine lactones signal cell activation through a mechanism distinct from the canonical pathogen-associated molecular pattern recognition receptor pathways.

Kravchenko VV, Kaufmann GF, Mathison JC, Scott DA, Katz AZ, Wood MR, Brogan AP, Lehmann M, Mee JM, Iwata K, Pan Q, Fearns C, Knaus UG, Meijler MM, Janda KD, Ulevitch RJ.

J Biol Chem. 2006 Sep 29;281(39):28822-30. Epub 2006 Aug 7.

50.

Vaccination against weight gain.

Zorrilla EP, Iwasaki S, Moss JA, Chang J, Otsuji J, Inoue K, Meijler MM, Janda KD.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13226-31. Epub 2006 Aug 4.

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