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Items: 1 to 50 of 71

1.

High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.

Moritz A, Anjanappa R, Wagner C, Bunk S, Hofmann M, Pszolla G, Saikia A, Garcia-Alai M, Meijers R, Rammensee HG, Springer S, Maurer D.

Sci Immunol. 2019 Jul 19;4(37). pii: eaav0860. doi: 10.1126/sciimmunol.aav0860.

PMID:
31324691
2.

Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells.

Saini SK, Tamhane T, Anjanappa R, Saikia A, Ramskov S, Donia M, Svane IM, Jakobsen SN, Garcia-Alai M, Zacharias M, Meijers R, Springer S, Hadrup SR.

Sci Immunol. 2019 Jul 19;4(37). pii: eaau9039. doi: 10.1126/sciimmunol.aau9039.

PMID:
31324690
3.

One-fits-all pretreatment protocol facilitating Fluorescence In Situ Hybridization on formalin-fixed paraffin-embedded, fresh frozen and cytological slides.

Richardson SO, Huibers MMH, de Weger RA, de Leng WWJ, Hinrichs JWJ, Meijers RWJ, Willems SM, Peeters TLMG.

Mol Cytogenet. 2019 Jun 17;12:27. doi: 10.1186/s13039-019-0442-4. eCollection 2019.

4.

Next-generation sequencing of immunoglobulin gene rearrangements for clonality assessment: a technical feasibility study by EuroClonality-NGS.

Scheijen B, Meijers RWJ, Rijntjes J, van der Klift MY, Möbs M, Steinhilber J, Reigl T, van den Brand M, Kotrová M, Ritter JM, Catherwood MA, Stamatopoulos K, Brüggemann M, Davi F, Darzentas N, Pott C, Fend F, Hummel M, Langerak AW, Groenen PJTA; EuroClonality-NGS Working Group.

Leukemia. 2019 Sep;33(9):2227-2240. doi: 10.1038/s41375-019-0508-7. Epub 2019 Jun 13.

PMID:
31197258
5.

Responsiveness of Chronic Lymphocytic Leukemia cells to B cell receptor stimulation is associated with low expression of regulatory molecules of the Nuclear Factor-κB pathway.

Meijers RWJ, Muggen AF, Leon LG, de Bie M, van Dongen JJM, Hendriks RW, Langerak AW.

Haematologica. 2019 May 16. pii: haematol.2018.215566. doi: 10.3324/haematol.2018.215566. [Epub ahead of print]

6.

Effects of bariatric surgery on telomere length and T-cell aging.

Jongbloed F, Meijers RWJ, IJzermans JNM, Klaassen RA, Dollé MET, van den Berg S, Betjes MGH, de Bruin RWF, van der Harst E, Litjens NHR.

Int J Obes (Lond). 2019 Apr 12. doi: 10.1038/s41366-019-0351-y. [Epub ahead of print]

PMID:
30979972
7.

Roles of glycosaminoglycans as regulators of ligand/receptor complexes.

Smock RG, Meijers R.

Open Biol. 2018 Oct 3;8(10). pii: 180026. doi: 10.1098/rsob.180026. Review.

8.

Identification of Distinct Unmutated Chronic Lymphocytic Leukemia Subsets in Mice Based on Their T Cell Dependency.

Pal Singh S, de Bruijn MJW, de Almeida MP, Meijers RWJ, Nitschke L, Langerak AW, Pillai SY, Stadhouders R, Hendriks RW.

Front Immunol. 2018 Sep 13;9:1996. doi: 10.3389/fimmu.2018.01996. eCollection 2018.

9.

Correction to: Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence.

Meijers RWJ, Dzierzanowska-Fangrat K, Zborowska M, Solarska I, Tielemans D, van Turnhout BAC, Driessen G, van der Burg M, van Dongen JJM, Chrzanowska KH, Langerak AW.

J Clin Immunol. 2018 May;38(4):538. doi: 10.1007/s10875-018-0503-1.

PMID:
29728794
10.

Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.

Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R.

Neuron. 2018 Mar 21;97(6):1261-1267.e4. doi: 10.1016/j.neuron.2018.02.010. Epub 2018 Mar 1.

11.

Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.

Falke S, Dierks K, Blanchet C, Graewert M, Cipriani F, Meijers R, Svergun D, Betzel C.

J Synchrotron Radiat. 2018 Mar 1;25(Pt 2):361-372. doi: 10.1107/S1600577517017568. Epub 2018 Feb 13.

PMID:
29488914
12.

The binding of DCC-P3 motif and FAK-FAT domain mediates the initial step of netrin-1/DCC signaling for axon attraction.

Xu S, Liu Y, Li X, Liu Y, Meijers R, Zhang Y, Wang JH.

Cell Discov. 2018 Feb 20;4:8. doi: 10.1038/s41421-017-0008-8. eCollection 2018.

13.

Epsin and Sla2 form assemblies through phospholipid interfaces.

Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R.

Nat Commun. 2018 Jan 23;9(1):328. doi: 10.1038/s41467-017-02443-x.

14.

Development of a specific fluorescent phage endolysin for in situ detection of Clostridium species associated with cheese spoilage.

Gómez-Torres N, Dunne M, Garde S, Meijers R, Narbad A, Ávila M, Mayer MJ.

Microb Biotechnol. 2018 Mar;11(2):332-345. doi: 10.1111/1751-7915.12883. Epub 2017 Nov 21.

15.

Protective Cytomegalovirus (CMV)-Specific T-Cell Immunity Is Frequent in Kidney Transplant Patients without Serum Anti-CMV Antibodies.

Litjens NHR, Huang L, Dedeoglu B, Meijers RWJ, Kwekkeboom J, Betjes MGH.

Front Immunol. 2017 Sep 12;8:1137. doi: 10.3389/fimmu.2017.01137. eCollection 2017.

16.

Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC.

Finci LI, Zhang J, Sun X, Smock RG, Meijers R, Zhang Y, Xiao J, Wang JH.

Protein Cell. 2017 Sep;8(9):701-705. doi: 10.1007/s13238-017-0439-x. No abstract available.

17.

Arterial Pressure, Heart Rate, and Cerebral Hemodynamics Across the Adult Life Span.

Xing CY, Tarumi T, Meijers RL, Turner M, Repshas J, Xiong L, Ding K, Vongpatanasin W, Yuan LJ, Zhang R.

Hypertension. 2017 Apr;69(4):712-720. doi: 10.1161/HYPERTENSIONAHA.116.08986. Epub 2017 Feb 13.

18.

Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence.

Meijers RWJ, Dzierzanowska-Fangrat K, Zborowska M, Solarska I, Tielemans D, van Turnhout BAC, Driessen G, van der Burg M, van Dongen JJM, Chrzanowska KH, Langerak AW.

J Clin Immunol. 2017 Feb;37(2):133-142. doi: 10.1007/s10875-016-0363-5. Epub 2016 Dec 21. Erratum in: J Clin Immunol. 2018 Apr 23;:.

19.

Editorial overview: New constructs and expression of proteins.

Meijers R, Perrakis A.

Curr Opin Struct Biol. 2016 Jun;38:v-vi. doi: 10.1016/j.sbi.2016.07.013. Epub 2016 Aug 9. No abstract available.

PMID:
27520611
20.

Critical reflections on synthetic gene design for recombinant protein expression.

Parret AH, Besir H, Meijers R.

Curr Opin Struct Biol. 2016 Jun;38:155-62. doi: 10.1016/j.sbi.2016.07.004. Epub 2016 Jul 21. Review.

21.

HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.

Papageorgiou AC, Adam PS, Stavros P, Nounesis G, Meijers R, Petratos K, Vorgias CE.

Extremophiles. 2016 Sep;20(5):695-709. doi: 10.1007/s00792-016-0859-1. Epub 2016 Jun 24.

PMID:
27342116
22.

Optimization of protein samples for NMR using thermal shift assays.

Kozak S, Lercher L, Karanth MN, Meijers R, Carlomagno T, Boivin S.

J Biomol NMR. 2016 Apr;64(4):281-9. doi: 10.1007/s10858-016-0027-z. Epub 2016 Mar 17.

23.

Loss of CD28 on Peripheral T Cells Decreases the Risk for Early Acute Rejection after Kidney Transplantation.

Dedeoglu B, Meijers RW, Klepper M, Hesselink DA, Baan CC, Litjens NH, Betjes MG.

PLoS One. 2016 Mar 7;11(3):e0150826. doi: 10.1371/journal.pone.0150826. eCollection 2016.

24.

Uremia-Associated Premature Aging of T Cells Does Not Predict Infectious Complications After Renal Transplantation.

Dedeoglu B, Meijers RW, Klepper M, Hesselink DA, Baan CC, Litjens NH, Betjes MG.

Am J Transplant. 2016 Aug;16(8):2324-33. doi: 10.1111/ajt.13759. Epub 2016 Mar 14.

25.

Crystal Structure of the CTP1L Endolysin Reveals How Its Activity Is Regulated by a Secondary Translation Product.

Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R.

J Biol Chem. 2016 Mar 4;291(10):4882-93. doi: 10.1074/jbc.M115.671172. Epub 2015 Dec 18.

26.

End stage renal disease patients have a skewed T cell receptor Vβ repertoire.

Huang L, Langerak AW, Wolvers-Tettero IL, Meijers RW, Baan CC, Litjens NH, Betjes MG.

Immun Ageing. 2015 Dec 14;12:28. doi: 10.1186/s12979-015-0055-7. eCollection 2015.

27.

An integrated pipeline for sample preparation and characterization at the EMBL@PETRA3 synchrotron facilities.

Boivin S, Kozak S, Rasmussen G, Nemtanu IM, Vieira V, Meijers R.

Methods. 2016 Feb 15;95:70-7. doi: 10.1016/j.ymeth.2015.08.003. Epub 2015 Aug 7.

PMID:
26255961
28.

Primary Cytomegalovirus Infection Significantly Impacts Circulating T Cells in Kidney Transplant Recipients.

Meijers RW, Litjens NH, Hesselink DA, Langerak AW, Baan CC, Betjes MG.

Am J Transplant. 2015 Dec;15(12):3143-56. doi: 10.1111/ajt.13396. Epub 2015 Jul 24.

29.

The crystal structure of Erwinia amylovora levansucrase provides a snapshot of the products of sucrose hydrolysis trapped into the active site.

Wuerges J, Caputi L, Cianci M, Boivin S, Meijers R, Benini S.

J Struct Biol. 2015 Sep;191(3):290-8. doi: 10.1016/j.jsb.2015.07.010. Epub 2015 Jul 21.

PMID:
26208466
30.

Structural Elucidation of the Bispecificity of A Domains as a Basis for Activating Non-natural Amino Acids.

Kaljunen H, Schiefelbein SH, Stummer D, Kozak S, Meijers R, Christiansen G, Rentmeister A.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8833-6. doi: 10.1002/anie.201503275. Epub 2015 Jun 11.

PMID:
26096082
31.

3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis DPN7(T): crystal structure and function of a desulfinase with an acyl-CoA dehydrogenase fold.

Schürmann M, Meijers R, Schneider TR, Steinbüchel A, Cianci M.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1360-72. doi: 10.1107/S1399004715006616. Epub 2015 May 23.

32.

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI.

Sci Rep. 2015 Jun 1;5:10734. doi: 10.1038/srep10734.

33.

An organized co-assembly of clathrin adaptors is essential for endocytosis.

Skruzny M, Desfosses A, Prinz S, Dodonova SO, Gieras A, Uetrecht C, Jakobi AJ, Abella M, Hagen WJ, Schulz J, Meijers R, Rybin V, Briggs JA, Sachse C, Kaksonen M.

Dev Cell. 2015 Apr 20;33(2):150-62. doi: 10.1016/j.devcel.2015.02.023.

34.

Signaling mechanism of the netrin-1 receptor DCC in axon guidance.

Finci L, Zhang Y, Meijers R, Wang JH.

Prog Biophys Mol Biol. 2015 Sep;118(3):153-60. doi: 10.1016/j.pbiomolbio.2015.04.001. Epub 2015 Apr 14. Review.

35.

T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance.

Meijers RW, Betjes MG, Baan CC, Litjens NH.

World J Nephrol. 2014 Nov 6;3(4):268-76. doi: 10.5527/wjn.v3.i4.268. Review.

36.

Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides.

Choo JA, Thong SY, Yap J, van Esch WJ, Raida M, Meijers R, Lescar J, Verhelst SH, Grotenbreg GM.

Angew Chem Int Ed Engl. 2014 Dec 1;53(49):13390-4. doi: 10.1002/anie.201406295. Epub 2014 Oct 27.

PMID:
25348595
37.

The crystal structure of netrin-1 in complex with DCC reveals the bifunctionality of netrin-1 as a guidance cue.

Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HDT, Svergun DI, Zhang Y, Wang JH, Meijers R.

Neuron. 2014 Aug 20;83(4):839-849. doi: 10.1016/j.neuron.2014.07.010. Epub 2014 Aug 7.

38.

Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation.

Meijers RW, Litjens NH, de Wit EA, Langerak AW, Baan CC, Betjes MG.

Transpl Int. 2014 Dec;27(12):1272-84. doi: 10.1111/tri.12416. Epub 2014 Sep 30.

39.

The CD27L and CTP1L endolysins targeting Clostridia contain a built-in trigger and release factor.

Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R.

PLoS Pathog. 2014 Jul 24;10(7):e1004228. doi: 10.1371/journal.ppat.1004228. eCollection 2014 Jul.

40.

Loss of renal function causes premature aging of the immune system.

Betjes MG, Meijers RW, Litjens NH.

Blood Purif. 2013;36(3-4):173-8. doi: 10.1159/000356084. Epub 2013 Dec 20. Review.

41.

Cytomegalovirus contributes partly to uraemia-associated premature immunological ageing of the T cell compartment.

Meijers RW, Litjens NH, de Wit EA, Langerak AW, van der Spek A, Baan CC, Weimar W, Betjes MG.

Clin Exp Immunol. 2013 Dec;174(3):424-32. doi: 10.1111/cei.12188.

42.

Optimization of protein purification and characterization using Thermofluor screens.

Boivin S, Kozak S, Meijers R.

Protein Expr Purif. 2013 Oct;91(2):192-206. doi: 10.1016/j.pep.2013.08.002. Epub 2013 Aug 12. Review.

PMID:
23948764
43.

Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients.

Meijers RW, Litjens NH, de Wit EA, Langerak AW, van der Spek A, Baan CC, Weimar W, Betjes MG.

Immun Ageing. 2012 Sep 12;9(1):19. doi: 10.1186/1742-4933-9-19.

44.

Terminally differentiated CD8+ Temra cells are associated with the risk for acute kidney allograft rejection.

Betjes MG, Meijers RW, de Wit EA, Weimar W, Litjens NH.

Transplantation. 2012 Jul 15;94(1):63-9. doi: 10.1097/TP.0b013e31825306ff.

PMID:
22691956
45.

A killer on the road: circulating CD4(+)CD28null T cells as cardiovascular risk factor in ESRD patients.

Betjes MG, Meijers RW, de Wit LE, Litjens NH.

J Nephrol. 2012 Mar-Apr;25(2):183-91. doi: 10.5301/jn.5000057. Review.

PMID:
22135034
46.

Structure-based modification of a Clostridium difficile-targeting endolysin affects activity and host range.

Mayer MJ, Garefalaki V, Spoerl R, Narbad A, Meijers R.

J Bacteriol. 2011 Oct;193(19):5477-86. doi: 10.1128/JB.00439-11. Epub 2011 Jul 29.

47.

Electrical transport properties of single undoped and n-type doped InN nanowires.

Richter T, Lüth H, Schäpers T, Meijers R, Jeganathan K, Estévez Hernández S, Calarco R, Marso M.

Nanotechnology. 2009 Oct 7;20(40):405206. doi: 10.1088/0957-4484/20/40/405206. Epub 2009 Sep 8.

PMID:
19738304
48.

Investigation on localized states in GaN nanowires.

Polenta L, Rossi M, Cavallini A, Calarco R, Marso M, Meijers R, Richter T, Stoica T, Lüth H.

ACS Nano. 2008 Feb;2(2):287-92. doi: 10.1021/nn700386w.

PMID:
19206629
49.

A variety of electrostatic interactions and adducts can activate NAD(P) cofactors for hydride transfer.

Meijers R, Cedergren-Zeppezauer E.

Chem Biol Interact. 2009 Mar 16;178(1-3):24-8. doi: 10.1016/j.cbi.2008.10.043. Epub 2008 Nov 5.

PMID:
19028476
50.

Acoustic charge transport in GaN nanowires.

Ebbecke J, Maisch S, Wixforth A, Calarco R, Meijers R, Marso M, Lüth H.

Nanotechnology. 2008 Jul 9;19(27):275708. doi: 10.1088/0957-4484/19/27/275708. Epub 2008 May 28.

PMID:
21828720

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