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Items: 1 to 50 of 68

1.

Endocytosis by macrophages: Interplay of macrophage scavenger receptor-1 and LDL receptor-related protein-1.

Béguin EP, Przeradzka MA, Janssen EFJ, Meems H, Sedek M, van der Zwaan C, Mertens K, van den Biggelaar M, Meijer AB, Mourik MJ.

Haematologica. 2019 Jun 27. pii: haematol.2018.210682. doi: 10.3324/haematol.2018.210682. [Epub ahead of print]

2.

A Homozygous Mutation on the HBA1 Gene Coding for Hb Charlieu (HBA1: c.320T>C) Together with β-Thalassemia Trait Results in Severe Hemolytic Anemia.

Klei TRL, Kheradmand Kia S, Veldthuis M, Dehbozorgian J, Karimi M, Geissler J, Sellink E, Thiel-Valkhof M, Burger P, van Alphen F, Meijer AB, van Bruggen R, van Zwieten R.

Hemoglobin. 2019 Mar;43(2):77-82. doi: 10.1080/03630269.2019.1601107. Epub 2019 Jun 13.

PMID:
31190578
3.

Glycoproteogenomics: a frequent gene polymorphism affects the glycosylation pattern of the human serum fetuin/α-2-HS-glycoprotein.

Lin YH, Zhu J, Meijer AB, Vojtech F, Heck AJR.

Mol Cell Proteomics. 2019 May 16. pii: mcp.RA119.001411. doi: 10.1074/mcp.RA119.001411. [Epub ahead of print]

4.

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

Volpi S, Cicalese MP, Tuijnenburg P, Tool ATJ, Cuadrado E, Abu-Halaweh M, Ahanchian H, Alzyoud R, Akdemir ZC, Barzaghi F, Blank A, Boisson B, Bottino C, Brigida I, Caorsi R, Casanova JL, Chiesa S, Chinn IK, Dückers G, Enders A, Erichsen HC, Forbes LR, Gambin T, Gattorno M, Karimiani EG, Giliani S, Gold MS, Jacobsen EM, Jansen MH, King JR, Laxer RM, Lupski JR, Mace E, Marcenaro S, Maroofian R, Meijer AB, Niehues T, Notarangelo LD, Orange J, Pannicke U, Pearson C, Picco P, Quinn PJ, Schulz A, Seeborg F, Stray-Pedersen A, Tawamie H, van Leeuwen EMM, Aiuti A, Yeung R, Schwarz K, Kuijpers TW.

J Allergy Clin Immunol. 2019 Jun;143(6):2296-2299. doi: 10.1016/j.jaci.2019.02.003. Epub 2019 Feb 13. No abstract available.

PMID:
30771411
5.

Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets.

van Oorschot R, Hansen M, Koornneef JM, Marneth AE, Bergevoet SM, van Bergen MGJM, van Alphen FPJ, van der Zwaan C, Martens JHA, Vermeulen M, Jansen PWTC, Baltissen MPA, Gorkom BAPL, Janssen H, Jansen JH, von Lindern M, Meijer AB, van den Akker E, van der Reijden BA.

Haematologica. 2019 Jul;104(7):1460-1472. doi: 10.3324/haematol.2018.194555. Epub 2019 Jan 17.

6.

Integrated proteomic analysis of tumor necrosis factor α and interleukin 1β-induced endothelial inflammation.

Béguin EP, van den Eshof BL, Hoogendijk AJ, Nota B, Mertens K, Meijer AB, van den Biggelaar M.

J Proteomics. 2019 Feb 10;192:89-101. doi: 10.1016/j.jprot.2018.08.011. Epub 2018 Aug 25.

PMID:
30153514
7.

Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.

Moore KS, Yagci N, van Alphen F, Meijer AB, 't Hoen PAC, von Lindern M.

PLoS One. 2018 Aug 23;13(8):e0201690. doi: 10.1371/journal.pone.0201690. eCollection 2018.

8.

The D' domain of von Willebrand factor requires the presence of the D3 domain for optimal factor VIII binding.

Przeradzka MA, Meems H, van der Zwaan C, Ebberink EHTM, van den Biggelaar M, Mertens K, Meijer AB.

Biochem J. 2018 Sep 11;475(17):2819-2830. doi: 10.1042/BCJ20180431.

PMID:
30111575
9.

Identifying Children with HEreditary Coagulation disorders (iCHEC): a protocol for a prospective cohort study.

Stokhuijzen E, Rand ML, Cnossen MH, Biss TT, James PD, Suijker MH, Peters M, van der Lee JH, Peters B, Meijer AB, Blanchette VS, Fijnvandraat K.

BMJ Open. 2018 May 3;8(5):e020686. doi: 10.1136/bmjopen-2017-020686.

10.

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

Hrdinová J, Verbij FC, Kaijen PHP, Hartholt RB, van Alphen F, Lardy N, Ten Brinke A, Vanhoorelbeke K, Hindocha PJ, De Groot AS, Meijer AB, Voorberg J, Peyron I.

Haematologica. 2018 Jun;103(6):1083-1092. doi: 10.3324/haematol.2017.179119. Epub 2018 Mar 22.

11.

Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans.

Tuijnenburg P, Lango Allen H, Burns SO, Greene D, Jansen MH, Staples E, Stephens J, Carss KJ, Biasci D, Baxendale H, Thomas M, Chandra A, Kiani-Alikhan S, Longhurst HJ, Seneviratne SL, Oksenhendler E, Simeoni I, de Bree GJ, Tool ATJ, van Leeuwen EMM, Ebberink EHTM, Meijer AB, Tuna S, Whitehorn D, Brown M, Turro E, Thrasher AJ, Smith KGC, Thaventhiran JE, Kuijpers TW; NIHR BioResource–Rare Diseases Consortium.

J Allergy Clin Immunol. 2018 Oct;142(4):1285-1296. doi: 10.1016/j.jaci.2018.01.039. Epub 2018 Mar 2.

12.

Csde1 binds transcripts involved in protein homeostasis and controls their expression in an erythroid cell line.

Moore KS, Yagci N, van Alphen F, Paolini NA, Horos R, Held NM, Houtkooper RH, van den Akker E, Meijer AB, 't Hoen PAC, von Lindern M.

Sci Rep. 2018 Feb 8;8(1):2628. doi: 10.1038/s41598-018-20518-7.

13.

Chemical Footprinting Reveals Conformational Changes Following Activation of Factor XI.

Stroo I, Marquart JA, Bakhtiari K, Plug T, Meijer AB, Meijers JCM.

Thromb Haemost. 2018 Feb;118(2):340-350. doi: 10.1160/TH17-09-0676. Epub 2018 Jan 29.

PMID:
29378358
14.

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Verbij FC, Sorvillo N, Kaijen PHP, Hrdinova J, Peyron I, Fijnheer R, Ten Brinke A, Meijer AB, van Alphen FPJ, van den Berg TK, Graversen JJH, Moestrup SK, Voorberg J.

Blood Adv. 2017 Jan 16;1(5):293-305. doi: 10.1182/bloodadvances.2016001321. eCollection 2017 Jan 24.

15.

Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells.

Peyron I, Hartholt RB, Pedró-Cos L, van Alphen F, Brinke AT, Lardy N, Meijer AB, Voorberg J.

Haematologica. 2018 Jan;103(1):172-178. doi: 10.3324/haematol.2017.175083. Epub 2017 Oct 12.

16.

Monitoring storage induced changes in the platelet proteome employing label free quantitative mass spectrometry.

Rijkers M, van den Eshof BL, van der Meer PF, van Alphen FPJ, de Korte D, Leebeek FWG, Meijer AB, Voorberg J, Jansen AJG.

Sci Rep. 2017 Sep 8;7(1):11045. doi: 10.1038/s41598-017-11643-w.

17.

Differences between Platelets Derived from Neonatal Cord Blood and Adult Peripheral Blood Assessed by Mass Spectrometry.

Stokhuijzen E, Koornneef JM, Nota B, van den Eshof BL, van Alphen FPJ, van den Biggelaar M, van der Zwaan C, Kuijk C, Mertens K, Fijnvandraat K, Meijer AB.

J Proteome Res. 2017 Oct 6;16(10):3567-3575. doi: 10.1021/acs.jproteome.7b00298. Epub 2017 Aug 30.

PMID:
28823163
18.

Paradigm of Biased PAR1 (Protease-Activated Receptor-1) Activation and Inhibition in Endothelial Cells Dissected by Phosphoproteomics.

van den Eshof BL, Hoogendijk AJ, Simpson PJ, van Alphen FPJ, Zanivan S, Mertens K, Meijer AB, van den Biggelaar M.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1891-1902. doi: 10.1161/ATVBAHA.117.309926. Epub 2017 Aug 17.

PMID:
28818855
19.

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

de Boer M, van Leeuwen K, Geissler J, van Alphen F, de Vries E, van der Kuip M, Terheggen SWJ, Janssen H, van den Berg TK, Meijer AB, Roos D, Kuijpers TW.

Hum Mutat. 2017 Oct;38(10):1402-1411. doi: 10.1002/humu.23271. Epub 2017 Jun 15.

PMID:
28585318
20.

Cellular uptake of coagulation factor VIII: Elusive role of the membrane-binding spikes in the C1 domain.

Castro-Núñez L, Koornneef JM, Rondaij MG, Bloem E, van der Zwaan C, Mertens K, Meijer AB, Meems H.

Int J Biochem Cell Biol. 2017 Aug;89:34-41. doi: 10.1016/j.biocel.2017.05.027. Epub 2017 May 27.

PMID:
28558995
21.

Label-free Analysis of CD8+ T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells.

van Aalderen MC, van den Biggelaar M, Remmerswaal EBM, van Alphen FPJ, Meijer AB, Ten Berge IJM, van Lier RAW.

Cell Rep. 2017 May 2;19(5):1068-1079. doi: 10.1016/j.celrep.2017.04.014.

22.

Role of glycine 221 in catalytic activity of hyaluronan-binding protein 2.

Stavenuiter F, Ebberink EHTM, Mertens K, Meijer AB.

J Biol Chem. 2017 Apr 14;292(15):6381-6388. doi: 10.1074/jbc.M116.757849. Epub 2017 Feb 27.

23.

Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.

Ebberink EH, Bouwens EA, Bloem E, Boon-Spijker M, van den Biggelaar M, Voorberg J, Meijer AB, Mertens K.

Haematologica. 2017 Apr;102(4):686-694. doi: 10.3324/haematol.2016.153163. Epub 2017 Jan 5.

24.

Combined immunodeficiency with severe inflammation and allergy caused by ARPC1B deficiency.

Kuijpers TW, Tool ATJ, van der Bijl I, de Boer M, van Houdt M, de Cuyper IM, Roos D, van Alphen F, van Leeuwen K, Cambridge EL, Arends MJ, Dougan G, Clare S, Ramirez-Solis R, Pals ST, Adams DJ, Meijer AB, van den Berg TK.

J Allergy Clin Immunol. 2017 Jul;140(1):273-277.e10. doi: 10.1016/j.jaci.2016.09.061. Epub 2016 Dec 10. No abstract available.

PMID:
27965109
25.

Identification of glycans on plasma-derived ADAMTS13.

Verbij FC, Stokhuijzen E, Kaijen PH, van Alphen F, Meijer AB, Voorberg J.

Blood. 2016 Nov 24;128(21):e51-e58. Epub 2016 Aug 29.

26.

Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation.

Ciudad MT, Sorvillo N, van Alphen FP, Catalán D, Meijer AB, Voorberg J, Jaraquemada D.

J Leukoc Biol. 2017 Jan;101(1):15-27. doi: 10.1189/jlb.6HI0216-069R. Epub 2016 Jun 30.

PMID:
27365532
27.

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components.

Gazendam RP, van de Geer A, van Hamme JL, Tool AT, van Rees DJ, Aarts CE, van den Biggelaar M, van Alphen F, Verkuijlen P, Meijer AB, Janssen H, Roos D, van den Berg TK, Kuijpers TW.

Haematologica. 2016 May;101(5):587-96. doi: 10.3324/haematol.2015.136630. Epub 2016 Jan 22.

28.

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII.

Sorvillo N, Hartholt RB, Bloem E, Sedek M, ten Brinke A, van der Zwaan C, van Alphen FP, Meijer AB, Voorberg J.

Haematologica. 2016 Mar;101(3):309-18. doi: 10.3324/haematol.2015.137067. Epub 2015 Dec 3.

29.

Factor VIII Interacts with the Endocytic Receptor Low-density Lipoprotein Receptor-related Protein 1 via an Extended Surface Comprising "Hot-Spot" Lysine Residues.

van den Biggelaar M, Madsen JJ, Faber JH, Zuurveld MG, van der Zwaan C, Olsen OH, Stennicke HR, Mertens K, Meijer AB.

J Biol Chem. 2015 Jul 3;290(27):16463-76. doi: 10.1074/jbc.M115.650911. Epub 2015 Apr 21.

30.

A novel chemical footprinting approach identifies critical lysine residues involved in the binding of receptor-associated protein to cluster II of LDL receptor-related protein.

Bloem E, Ebberink EH, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB.

Biochem J. 2015 May 15;468(1):65-72. doi: 10.1042/BJ20140977.

PMID:
25728577
31.

PKCδ is dispensible for oxLDL uptake and foam cell formation by human and murine macrophages.

Szilagyi K, Meijer AB, Neele AE, Verkuijlen P, Leitges M, Dabernat S, Förster-Waldl E, Boztug K, Belot A, Kuijpers TW, Kraal G, de Winther MP, van den Berg TK.

Cardiovasc Res. 2014 Dec 1;104(3):467-76. doi: 10.1093/cvr/cvu213. Epub 2014 Sep 24.

PMID:
25253077
32.

Identification of N-linked glycosylation and putative O-fucosylation, C-mannosylation sites in plasma derived ADAMTS13.

Sorvillo N, Kaijen PH, Matsumoto M, Fujimura Y, van der Zwaan C, Verbij FC, Pos W, Fijnheer R, Voorberg J, Meijer AB.

J Thromb Haemost. 2014 May;12(5):670-9.

PMID:
24977290
33.

Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells.

van den Biggelaar M, Hernández-Fernaud JR, van den Eshof BL, Neilson LJ, Meijer AB, Mertens K, Zanivan S.

Blood. 2014 Mar 20;123(12):e22-36. doi: 10.1182/blood-2013-12-546036. Epub 2014 Feb 5.

34.

Phosphatidylinositol-3,4,5-triphosphate-dependent Rac exchange factor 1 regulates epinephrine-induced exocytosis of Weibel-Palade bodies.

van Hooren KW, van Breevoort D, Fernandez-Borja M, Meijer AB, Eikenboom J, Bierings R, Voorberg J.

J Thromb Haemost. 2014 Feb;12(2):273-81. doi: 10.1111/jth.12460.

35.

Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII.

van Haren SD, Wroblewska A, Herczenik E, Kaijen PH, Ruminska A, ten Brinke A, Meijer AB, Voorberg J.

PLoS One. 2013 Nov 14;8(11):e80239. doi: 10.1371/journal.pone.0080239. eCollection 2013.

36.

Factor VIII C1 domain spikes 2092-2093 and 2158-2159 comprise regions that modulate cofactor function and cellular uptake.

Bloem E, van den Biggelaar M, Wroblewska A, Voorberg J, Faber JH, Kjalke M, Stennicke HR, Mertens K, Meijer AB.

J Biol Chem. 2013 Oct 11;288(41):29670-9. doi: 10.1074/jbc.M113.473116. Epub 2013 Sep 5.

37.

A3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IX.

Bloem E, Meems H, van den Biggelaar M, Mertens K, Meijer AB.

J Biol Chem. 2013 Sep 6;288(36):26105-11. doi: 10.1074/jbc.M113.500884. Epub 2013 Jul 24.

38.

Defects in neutrophil granule mobilization and bactericidal activity in familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) syndrome caused by STXBP2/Munc18-2 mutations.

Zhao XW, Gazendam RP, Drewniak A, van Houdt M, Tool AT, van Hamme JL, Kustiawan I, Meijer AB, Janssen H, Russell DG, van de Corput L, Tesselaar K, Boelens JJ, Kuhnle I, Van Der Werff Ten Bosch J, Kuijpers TW, van den Berg TK.

Blood. 2013 Jul 4;122(1):109-11. doi: 10.1182/blood-2013-03-494039. Epub 2013 May 17.

39.

Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.

Sorvillo N, van Haren SD, Kaijen PH, ten Brinke A, Fijnheer R, Meijer AB, Voorberg J.

Blood. 2013 Apr 25;121(17):3502-10. doi: 10.1182/blood-2012-09-456780. Epub 2013 Jan 31.

40.

Potassium leakage primes stored erythrocytes for phosphatidylserine exposure and shedding of pro-coagulant vesicles.

Burger P, Kostova E, Bloem E, Hilarius-Stokman P, Meijer AB, van den Berg TK, Verhoeven AJ, de Korte D, van Bruggen R.

Br J Haematol. 2013 Feb;160(3):377-86. doi: 10.1111/bjh.12133. Epub 2012 Nov 28.

PMID:
23190498
41.

Distinct roles of Ser-764 and Lys-773 at the N terminus of von Willebrand factor in complex assembly with coagulation factor VIII.

Castro-Núñez L, Bloem E, Boon-Spijker MG, van der Zwaan C, van den Biggelaar M, Mertens K, Meijer AB.

J Biol Chem. 2013 Jan 4;288(1):393-400. doi: 10.1074/jbc.M112.400572. Epub 2012 Nov 20.

42.

Factors VIII and V swap fatty feet.

Mertens K, Meijer AB.

Blood. 2012 Aug 30;120(9):1761-3. doi: 10.1182/blood-2012-07-434027. No abstract available.

43.

Shear stress is required for the endocytic uptake of the factor VIII-von Willebrand factor complex by macrophages.

Castro-Núñez L, Dienava-Verdoold I, Herczenik E, Mertens K, Meijer AB.

J Thromb Haemost. 2012 Sep;10(9):1929-37. doi: 10.1111/j.1538-7836.2012.04860.x.

44.

Modification of an exposed loop in the C1 domain reduces immune responses to factor VIII in hemophilia A mice.

Wroblewska A, van Haren SD, Herczenik E, Kaijen P, Ruminska A, Jin SY, Zheng XL, van den Biggelaar M, ten Brinke A, Meijer AB, Voorberg J.

Blood. 2012 May 31;119(22):5294-300. doi: 10.1182/blood-2011-11-391680. Epub 2012 Apr 12.

45.

Proteomic screen identifies IGFBP7 as a novel component of endothelial cell-specific Weibel-Palade bodies.

van Breevoort D, van Agtmaal EL, Dragt BS, Gebbinck JK, Dienava-Verdoold I, Kragt A, Bierings R, Horrevoets AJ, Valentijn KM, Eikenboom JC, Fernandez-Borja M, Meijer AB, Voorberg J.

J Proteome Res. 2012 May 4;11(5):2925-36. doi: 10.1021/pr300010r. Epub 2012 Apr 12.

PMID:
22468712
46.

Novel role for galectin-8 protein as mediator of coagulation factor V endocytosis by megakaryocytes.

Zappelli C, van der Zwaan C, Thijssen-Timmer DC, Mertens K, Meijer AB.

J Biol Chem. 2012 Mar 9;287(11):8327-35. doi: 10.1074/jbc.M111.305151. Epub 2012 Jan 20.

47.

Factor seven activating protease (FSAP): does it activate factor VII?

Stavenuiter F, Dienava-Verdoold I, Boon-Spijker MG, Brinkman HJ, Meijer AB, Mertens K.

J Thromb Haemost. 2012 May;10(5):859-66. doi: 10.1111/j.1538-7836.2012.04619.x.

48.

Mass spectrometry-assisted study reveals that lysine residues 1967 and 1968 have opposite contribution to stability of activated factor VIII.

Bloem E, Meems H, van den Biggelaar M, van der Zwaan C, Mertens K, Meijer AB.

J Biol Chem. 2012 Feb 17;287(8):5775-83. doi: 10.1074/jbc.M111.308627. Epub 2012 Jan 3.

49.

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.

Herczenik E, van Haren SD, Wroblewska A, Kaijen P, van den Biggelaar M, Meijer AB, Martinez-Pomares L, ten Brinke A, Voorberg J.

J Allergy Clin Immunol. 2012 Feb;129(2):501-9, 509.e1-5. doi: 10.1016/j.jaci.2011.08.029. Epub 2011 Oct 1.

PMID:
21962992
50.

C1 domain residues Lys 2092 and Phe 2093 are of major importance for the endocytic uptake of coagulation factor VIII.

Meems H, van den Biggelaar M, Rondaij M, van der Zwaan C, Mertens K, Meijer AB.

Int J Biochem Cell Biol. 2011 Aug;43(8):1114-21. doi: 10.1016/j.biocel.2011.03.014. Epub 2011 Apr 8.

PMID:
21497669

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