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Items: 1 to 50 of 67

1.

The Avian EB66(R) Cell Line, Application to Vaccines, and Therapeutic Protein Production.

Brown SW, Mehtali M.

PDA J Pharm Sci Technol. 2010 Sep-Oct;64(5):419-25.

PMID:
21502045
2.

EB66 cell line, a duck embryonic stem cell-derived substrate for the industrial production of therapeutic monoclonal antibodies with enhanced ADCC activity.

Olivier S, Jacoby M, Brillon C, Bouletreau S, Mollet T, Nerriere O, Angel A, Danet S, Souttou B, Guehenneux F, Gauthier L, Berthomé M, Vié H, Beltraminelli N, Mehtali M.

MAbs. 2010 Jul-Aug;2(4):405-15. Epub 2010 Jul 1.

3.

[Alternative production systems for therapeutic monoclonal antibodies].

Olivier S, Mehtali M.

Med Sci (Paris). 2009 Dec;25(12):1163-8. doi: 10.1051/medsci/200925121163. Review. French. No abstract available.

4.

Gene transfer into canine myoblasts.

Braun S, Thioudellet C, Perraud F, Escriou C, Claudepierre MC, Homann H, Lusky M, Mehtali M, Bischoff R, Pavirani A.

Cytotechnology. 1999 Jul;30(1-3):181-9. doi: 10.1023/A:1008026913715.

5.

Inhibition of costimulation allows for repeated systemic administration of adenoviral vector in rhesus monkeys.

Haegel-Kronenberger H, Haanstra K, Ziller-Remy C, Ortiz Buijsse AP, Vermeiren J, Stoeckel F, Van Gool SW, Ceuppens JL, Mehtali M, De Boer M, Jonker M, Boon L.

Gene Ther. 2004 Feb;11(3):241-52.

PMID:
14737083
6.

Transductional targeting with recombinant adenovirus vectors.

Legrand V, Leissner P, Winter A, Mehtali M, Lusky M.

Curr Gene Ther. 2002 Sep;2(3):323-39. Review.

PMID:
12189719
7.

Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease.

Havenga MJ, Lemckert AA, Ophorst OJ, van Meijer M, Germeraad WT, Grimbergen J, van Den Doel MA, Vogels R, van Deutekom J, Janson AA, de Bruijn JD, Uytdehaag F, Quax PH, Logtenberg T, Mehtali M, Bout A.

J Virol. 2002 May;76(9):4612-20.

8.

Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism.

Leissner P, Legrand V, Schlesinger Y, Hadji DA, van Raaij M, Cusack S, Pavirani A, Mehtali M.

Gene Ther. 2001 Jan;8(1):49-57.

9.

The human cell line PER.C6 provides a new manufacturing system for the production of influenza vaccines.

Pau MG, Ophorst C, Koldijk MH, Schouten G, Mehtali M, Uytdehaag F.

Vaccine. 2001 Mar 21;19(17-19):2716-21.

PMID:
11257414
10.

Differential influence of the E4 adenoviral genes on viral and cellular promoters.

Grave L, Dreyer D, Dieterle A, Leroy P, Michou AI, Doderer C, Pavirani A, Lusky M, Mehtali M.

J Gene Med. 2000 Nov-Dec;2(6):433-43.

PMID:
11199264
11.

Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy.

Lerondel S, Le Pape A, Sené C, Faure L, Bernard S, Diot P, Nicolis E, Mehtali M, Lusky M, Cabrini G, Pavirani A.

Hum Gene Ther. 2001 Jan 1;12(1):1-11.

PMID:
11177537
12.

Gene transfer of anti-gp41 antibody and CD4 immunoadhesin strongly reduces the HIV-1 load in humanized severe combined immunodeficient mice.

Sanhadji K, Grave L, Touraine JL, Leissner P, Rouzioux C, Firouzi R, Kehrli L, Tardy JC, Mehtali M.

AIDS. 2000 Dec 22;14(18):2813-22.

PMID:
11153662
13.

A preclinical model of hepatocyte gene transfer: the in vivo, in situ perfused rat liver.

De Godoy JL, Malafosse R, Fabre M, Mitchell C, Mehtali M, Houssin D, Soubrane O.

Gene Ther. 2000 Nov;7(21):1816-23.

14.

Characterization of novel safe lentiviral vectors derived from simian immunodeficiency virus (SIVmac251) that efficiently transduce mature human dendritic cells.

Nègre D, Mangeot PE, Duisit G, Blanchard S, Vidalain PO, Leissner P, Winter AJ, Rabourdin-Combe C, Mehtali M, Moullier P, Darlix JL, Cosset FL.

Gene Ther. 2000 Oct;7(19):1613-23.

15.

Phase I clinical trial with IL-2-transfected xenogeneic cells administered in subcutaneous metastatic tumours: clinical and immunological findings.

Tartour E, Mehtali M, Sastre-Garau X, Joyeux I, Mathiot C, Pleau JM, Squiban P, Rochlitz C, Courtney M, Jantscheff P, Herrmann R, Pouillart P, Fridman WH, Dorval T.

Br J Cancer. 2000 Dec;83(11):1454-61.

16.

Optimization of bovine coronavirus hemagglutinin-estrase glycoprotein expression in E3 deleted bovine adenovirus-3.

Reddy PS, Idamakanti N, Zakhartchouk LN, Babiuk LA, Mehtali M, Tikoo SK.

Virus Res. 2000 Sep;70(1-2):65-73.

PMID:
11074126
17.

Development of minimal lentivirus vectors derived from simian immunodeficiency virus (SIVmac251) and their use for gene transfer into human dendritic cells.

Mangeot PE, Nègre D, Dubois B, Winter AJ, Leissner P, Mehtali M, Kaiserlian D, Cosset FL, Darlix JL.

J Virol. 2000 Sep;74(18):8307-15.

18.

In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene.

Erbs P, Regulier E, Kintz J, Leroy P, Poitevin Y, Exinger F, Jund R, Mehtali M.

Cancer Res. 2000 Jul 15;60(14):3813-22.

19.

Immune response to recombinant adenovirus in humans: capsid components from viral input are targets for vector-specific cytotoxic T lymphocytes.

Molinier-Frenkel V, Gahery-Segard H, Mehtali M, Le Boulaire C, Ribault S, Boulanger P, Tursz T, Guillet JG, Farace F.

J Virol. 2000 Aug;74(16):7678-82.

20.

Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products.

Christ M, Louis B, Stoeckel F, Dieterle A, Grave L, Dreyer D, Kintz J, Ali Hadji D, Lusky M, Mehtali M.

Hum Gene Ther. 2000 Feb 10;11(3):415-27.

PMID:
10697116
21.

Deletion of the fiber gene induces the storage of hexon and penton base proteins in PML/Sp100-containing inclusions during adenovirus infection.

Puvion-Dutilleul F, Legrand V, Mehtali M, Chelbi-Alix MK, de Thé H, Puvion E.

Biol Cell. 1999 Nov;91(8):617-28.

PMID:
10629941
22.

Porcine adenovirus-3 as a helper-dependent expression vector.

Reddy PS, Idamakanti N, Babiuk LA, Mehtali M, Tikoo SK.

J Gen Virol. 1999 Nov;80 ( Pt 11):2909-16.

PMID:
10580052
23.

Adenoviruses activate human dendritic cells without polarization toward a T-helper type 1-inducing subset.

Rea D, Schagen FH, Hoeben RC, Mehtali M, Havenga MJ, Toes RE, Melief CJ, Offringa R.

J Virol. 1999 Dec;73(12):10245-53.

24.

Replication-defective bovine adenovirus type 3 as an expression vector.

Reddy PS, Idamakanti N, Chen Y, Whale T, Babiuk LA, Mehtali M, Tikoo SK.

J Virol. 1999 Nov;73(11):9137-44.

25.

Development of a direct in situ RT-PCR method using labeled primers to detect cytokine mRNA inside cells.

Gey A, Hamdi S, Vielh P, Mehtali M, Fridman WH, Tartour E.

J Immunol Methods. 1999 Jul 30;227(1-2):149-60.

PMID:
10485262
26.

Regulation of adenovirus-mediated transgene expression by the viral E4 gene products: requirement for E4 ORF3.

Lusky M, Grave L, Dieterlé A, Dreyer D, Christ M, Ziller C, Furstenberger P, Kintz J, Hadji DA, Pavirani A, Mehtali M.

J Virol. 1999 Oct;73(10):8308-19.

27.

Gene therapy with cytokine-transfected xenogenic cells (Vero-IL-2) in patients with metastatic solid tumors: mechanism(s) of elimination of the transgene-carrying cells.

Jantscheff P, Herrmann R, Spagnoli G, Reuter J, Mehtali M, Courtney M, Rochlitz C.

Cancer Immunol Immunother. 1999 Sep;48(6):321-30.

PMID:
10473807
28.
29.

Induced expression of B7-1 on myeloma cells following retroviral gene transfer results in tumor-specific recognition by cytotoxic T cells.

Tarte K, Zhang XG, Legouffe E, Hertog C, Mehtali M, Rossi JF, Klein B.

J Immunol. 1999 Jul 1;163(1):514-24.

30.

Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR.

Santis G, Legrand V, Hong SS, Davison E, Kirby I, Imler JL, Finberg RW, Bergelson JM, Mehtali M, Boulanger P.

J Gen Virol. 1999 Jun;80 ( Pt 6):1519-27.

PMID:
10374971
31.

Gene therapy study of cytokine-transfected xenogeneic cells (Vero-interleukin-2) in patients with metastatic solid tumors.

Rochlitz C, Jantscheff P, Bongartz G, Dietrich PY, Quiquerez AL, Schatz C, Mehtali M, Courtney M, Tartour E, Dorval T, Fridman WH, Herrmann R.

Cancer Gene Ther. 1999 May-Jun;6(3):271-81.

32.

Gene therapy with cytokine-transfected xenogeneic cells in metastatic tumors.

Rochlitz CF, Jantscheff P, Bongartz G, Dietrich PY, Quiquerez AL, Schatz C, Mehtali M, Courtney M, Tartour E, Dorval T, Fridman WH, Herrmann R.

Adv Exp Med Biol. 1998;451:531-7.

PMID:
10026923
33.

In vivo hepatocyte retrovirus-mediated gene transfer through the rat biliary tract.

De Godoy JL, Malafosse R, Fabre M, Mehtali M, Houssin D, Soubrane O.

Hum Gene Ther. 1999 Jan 20;10(2):249-57.

PMID:
10022549
34.

Fiberless recombinant adenoviruses: virus maturation and infectivity in the absence of fiber.

Legrand V, Spehner D, Schlesinger Y, Settelen N, Pavirani A, Mehtali M.

J Virol. 1999 Feb;73(2):907-19.

35.

Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes.

Leroy P, Slos P, Homann H, Erbs P, Poitevin Y, Regulier E, Colonna FQ, Devauchelle P, Roth C, Pavirani A, Mehtali M.

Res Immunol. 1998 Sep-Oct;149(7-8):681-4. Review. No abstract available.

PMID:
9851523
36.

Construction and characterization of E3-deleted bovine adenovirus type 3 expressing full-length and truncated form of bovine herpesvirus type 1 glycoprotein gD.

Zakhartchouk AN, Reddy PS, Baxi M, Baca-Estrada ME, Mehtali M, Babiuk LA, Tikoo SK.

Virology. 1998 Oct 10;250(1):220-9.

37.

[In vitro and in vivo inhibition of HIV1 replication by retroviral transfer of interferon alpha, beta, or gamma genes: application to gene therapy of AIDS].

Leissner P, Calenda V, Marigliano M, Sanhadji K, Touraine JL, Pavirani A, Mehtali M.

Ann Biol Clin (Paris). 1998 Mar-Apr;56(2):167-73. Review. French.

38.

In vitro and in vivo antitumor effects of retrovirus-mediated herpes simplex thymidine kinase gene-transfer in human medulloblastoma.

Rosolen A, Frascella E, di Francesco C, Todesco A, Petrone M, Mehtali M, Zacchello F, Zanesco L, Scarpa M.

Gene Ther. 1998 Jan;5(1):113-20.

39.

In vitro and in vivo biology of recombinant adenovirus vectors with E1, E1/E2A, or E1/E4 deleted.

Lusky M, Christ M, Rittner K, Dieterle A, Dreyer D, Mourot B, Schultz H, Stoeckel F, Pavirani A, Mehtali M.

J Virol. 1998 Mar;72(3):2022-32.

40.

Protection of SIVmac-infected macaque monkeys against superinfection by a simian immunodeficiency virus expressing envelope glycoproteins of HIV type 1.

Dunn CS, Hurtrel B, Beyer C, Gloeckler L, Ledger TN, Moog C, Kieny MP, Mehtali M, Schmitt D, Gut JP, Kirn A, Aubertin AM.

AIDS Res Hum Retroviruses. 1997 Jul 20;13(11):913-22.

PMID:
9223407
41.

Experimental gene therapy: the transfer of Tat-inducible interferon genes protects human cells against HIV-1 challenge in vitro and in vivo in severe combined immunodeficient mice.

Sanhadji K, Leissner P, Firouzi R, Pelloquin F, Kehrli L, Marigliano M, Calenda V, Ottmann M, Tardy JC, Mehtali M, Touraine JL.

AIDS. 1997 Jul;11(8):977-86.

PMID:
9223731
42.

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response.

Christ M, Lusky M, Stoeckel F, Dreyer D, Dieterlé A, Michou AI, Pavirani A, Mehtali M.

Immunol Lett. 1997 Jun 1;57(1-3):19-25.

PMID:
9232420
43.

Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression.

Michou AI, Santoro L, Christ M, Julliard V, Pavirani A, Mehtali M.

Gene Ther. 1997 May;4(5):473-82.

44.

Variegated gene expression in mice.

Dobie K, Mehtali M, McClenaghan M, Lathe R.

Trends Genet. 1997 Apr;13(4):127-30. Review. No abstract available.

PMID:
9097721
46.

[Genetic therapy for hemophiliacs--therapeutic potential and technological limits].

Michou AI, Christ M, Pavirani A, Mehtali M.

Transfus Clin Biol. 1997;4(3):251-61. Review. French.

PMID:
9264782
47.

Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin-2.

Quintin-Colonna F, Devauchelle P, Fradelizi D, Mourot B, Faure T, Kourilsky P, Roth C, Mehtali M.

Gene Ther. 1996 Dec;3(12):1104-12.

PMID:
8986437
48.

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli.

Chartier C, Degryse E, Gantzer M, Dieterle A, Pavirani A, Mehtali M.

J Virol. 1996 Jul;70(7):4805-10.

49.

Gene therapy for HIV infection.

Calenda V, Leissner P, Marigliano M, Mehtali M.

Hematol Cell Ther. 1996 Apr;38(2):211-3. Review. No abstract available.

PMID:
8932008
50.

Novel complementation cell lines derived from human lung carcinoma A549 cells support the growth of E1-deleted adenovirus vectors.

Imler JL, Chartier C, Dreyer D, Dieterle A, Sainte-Marie M, Faure T, Pavirani A, Mehtali M.

Gene Ther. 1996 Jan;3(1):75-84.

PMID:
8929914

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