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Nitrenium Salts in Lewis Acid Catalysis.

Mehta M, Goicoechea JM.

Angew Chem Int Ed Engl. 2019 Dec 6. doi: 10.1002/anie.201915547. [Epub ahead of print]


Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.

Magen A, Nie J, Ciucci T, Tamoutounour S, Zhao Y, Mehta M, Tran B, McGavern DB, Hannenhalli S, Bosselut R.

Cell Rep. 2019 Dec 3;29(10):3019-3032.e6. doi: 10.1016/j.celrep.2019.10.131.


High-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539.

Rogers CL, Won M, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Galvin J, Fogh SE, Youssef E, Deb N, Kwok Y, Robinson CG, Shu HK, Fisher BJ, Panet-Raymond V, McMillan WG, de Groot JF, Zhang P, Mehta MP.

Int J Radiat Oncol Biol Phys. 2019 Nov 28. pii: S0360-3016(19)34067-2. doi: 10.1016/j.ijrobp.2019.11.028. [Epub ahead of print]


Effectiveness of long-term infliximab use and impact of treatment adherence on disease control in refractory, non-infectious pediatric uveitis.

Miraldi Utz V, Bulas S, Lopper S, Fenchel M, Sa T, Mehta M, Ash D, Lovell DJ, Kaufman AH.

Pediatr Rheumatol Online J. 2019 Nov 29;17(1):79. doi: 10.1186/s12969-019-0383-9.


IL-24 Inhibits Lung Cancer Growth by Suppressing GLI1 and Inducing DNA Damage.

Panneerselvam J, Srivastava A, Mehta M, Chen A, Zhao YD, Munshi A, Ramesh R.

Cancers (Basel). 2019 Nov 27;11(12). pii: E1879. doi: 10.3390/cancers11121879.


Normalizing the Abnormal: Do Antipsychotic Drugs Push the Cortex Into an Unsustainable Metabolic Envelope?

Turkheimer FE, Selvaggi P, Mehta MA, Veronese M, Zelaya F, Dazzan P, Vernon AC.

Schizophr Bull. 2019 Nov 22. pii: sbz119. doi: 10.1093/schbul/sbz119. [Epub ahead of print]


Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization.

Sinha N, Karche NP, Verma MK, Walunj SS, Nigade PB, Jana G, Kurhade SP, Hajare AK, Tilekar AR, Jadhav GR, Thube BR, Shaikh JS, Balgude S, Singh LB, Mahimane V, Adurkar SK, Hatnapure G, Raje F, Bhosale Y, Bhanage D, Sachchidanand S, Dixit R, Gupta R, Bokare AM, Dandekar M, Bharne A, Chatterjee M, Desai S, Koul S, Modi D, Mehta M, Patil V, Singh M, Gundu J, Goel RN, Shah C, Sharma S, Bakhle D, Kamboj RK, Palle VP.

J Med Chem. 2019 Dec 6. doi: 10.1021/acs.jmedchem.9b01569. [Epub ahead of print]


Emerging Complexity and the Need for Advanced Drug Delivery in Targeting Candida Species.

Wadhwa R, Pandey P, Gupta G, Aggarwal T, Kumar N, Mehta M, Satija S, Gulati M, Madan J, Dureja H, Balusamy SR, Perumalsamy H, K Maurya P, Collet T, Tambuwala MM, Hansbro PM, Chellappan DK, Dua K.

Curr Top Med Chem. 2019 Oct 25. doi: 10.2174/1568026619666191026105308. [Epub ahead of print]


Raman spectroscopy reveals distinct differences between two closely related bacterial strains, Mycobacterium indicus pranii and Mycobacterium intracellulare.

Verma T, Podder S, Mehta M, Singh S, Singh A, Umapathy S, Nandi D.

Anal Bioanal Chem. 2019 Nov 16. doi: 10.1007/s00216-019-02197-z. [Epub ahead of print]


Targeting redox heterogeneity to counteract drug tolerance in replicating Mycobacterium tuberculosis.

Mishra R, Kohli S, Malhotra N, Bandyopadhyay P, Mehta M, Munshi M, Adiga V, Ahuja VK, Shandil RK, Rajmani RS, Seshasayee ASN, Singh A.

Sci Transl Med. 2019 Nov 13;11(518). pii: eaaw6635. doi: 10.1126/scitranslmed.aaw6635.


Short-term safety and effectiveness of sugammadex for surgical patients with end-stage renal disease: a two-centre retrospective study.

Adams DR, Tollinche LE, Yeoh CB, Artman J, Mehta M, Phillips D, Fischer GW, Quinlan JJ, Sakai T.

Anaesthesia. 2019 Nov 12. doi: 10.1111/anae.14914. [Epub ahead of print]


Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate.

Ramdas V, Talwar R, Banerjee M, Joshi AA, Das AK, Walke DS, Borhade P, Dhayagude U, Loriya R, Gote G, Bommakanti A, Sivaram A, Agarwal G, Goswami A, Nigade P, Mehta M, Patil V, Modi D, Kumar H, Mallurwar S, Dash A, Modi F, Kuldharan S, Srivastava P, Singh M, Narasimham L, Gundu J, Sharma S, Kamboj RK, Palle VP.

J Med Chem. 2019 Nov 22. doi: 10.1021/acs.jmedchem.9b01562. [Epub ahead of print]


Biological activity of weekly ONC201 in adult recurrent glioblastoma patients.

Arrillaga-Romany I, Odia Y, Prabhu VV, Tarapore RS, Merdinger K, Stogniew M, Oster W, Allen JE, Mehta M, Batchelor TT, Wen PY.

Neuro Oncol. 2019 Nov 8. pii: noz164. doi: 10.1093/neuonc/noz164. [Epub ahead of print]


The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress.

Dua K, Wadhwa R, Singhvi G, Rapalli V, Shukla SD, Shastri MD, Gupta G, Satija S, Mehta M, Khurana N, Awasthi R, Maurya PK, Thangavelu L, S R, Tambuwala MM, Collet T, Hansbro PM, Chellappan DK.

Drug Dev Res. 2019 Sep;80(6):714-730. doi: 10.1002/ddr.21571. Epub 2019 Jul 16. Review.


Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms.

Soon L, Ng PQ, Chellian J, Madheswaran T, Panneerselvam J, Gupta G, Nammi S, Hansbro NG, Hsu A, Dureja H, Mehta M, Satija S, Hansbro PM, Dua K, Collet T, Chellappan DK.

J Environ Pathol Toxicol Oncol. 2019;38(3):205-216. doi: 10.1615/JEnvironPatholToxicolOncol.2019029397. Review.


Pretreatment Volume of MRI-Determined White Matter Injury Predicts Neurocognitive Decline After Hippocampal Avoidant Whole-Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology Radiation Therapy Oncology Group 0933.

Bovi JA, Pugh SL, Sabsevitz D, Robinson CG, Paulson E, Mehta MP, Gondi V, Kundapur V, Shahin MS, Chao ST, Machtay M, DeNittis AS, Laack NN, Greenspoon JN, Moore KN, Huang J, Dominello MM, Kachnic LA.

Adv Radiat Oncol. 2019 Jul 16;4(4):579-586. doi: 10.1016/j.adro.2019.07.006. eCollection 2019 Oct-Dec.


Evaluation of reporting of CONSORT flow diagrams in randomized controlled trials in a national and international pharmacology journal.

Shaikh AM, Mehta MM, Chawan VV.

Perspect Clin Res. 2019 Oct-Dec;10(4):168-171. doi: 10.4103/picr.PICR_73_18.


High-Throughput Detection of Bacterial Community and Its Drug-Resistance Profiling From Local Reclaimed Wastewater Plants.

Limayem A, Wasson S, Mehta M, Pokhrel AR, Patil S, Nguyen M, Chen J, Nayak B.

Front Cell Infect Microbiol. 2019 Oct 4;9:303. doi: 10.3389/fcimb.2019.00303. eCollection 2019.


Prolonged Duration Topical Corneal Anesthesia With the Cationic Lidocaine Derivative QX-314.

Woodruff AG, Santamaria CM, Mehta M, Pemberton GL, Cullion K, Kohane DS.

Transl Vis Sci Technol. 2019 Oct 17;8(5):28. doi: 10.1167/tvst.8.5.28. eCollection 2019 Sep.


Insights into human factor studies conducted for US FDA-approved biological combination products.

Patel R, Mehta M, Pipalava P, Dahiya M, Singh I, Jose V.

Expert Opin Drug Deliv. 2019 Oct 29:1-21. doi: 10.1080/17425247.2019.1682995. [Epub ahead of print]


Ni-Catalyzed Suzuki-Miyaura Cross-Coupling of Aliphatic Amides on the Benchtop.

Mehta MM, Boit TB, Dander JE, Garg NK.

Org Lett. 2019 Oct 17. doi: 10.1021/acs.orglett.9b03434. [Epub ahead of print]


Inflammation and depressive phenotypes: evidence from medical records from over 12 000 patients and brain morphology.

Ironside M, Admon R, Maddox SA, Mehta M, Douglas S, Olson DP, Pizzagalli DA.

Psychol Med. 2019 Oct 16:1-9. doi: 10.1017/S0033291719002940. [Epub ahead of print]


Survey of residency program directors' perceptions of nontraditional pharmacy residency applicants.

Khalil AJ, Mediwala KN, Mehta M, Yanicak AJ, Ham JS, Blake EW, Rumley KF, Pan I, Bookstaver PB.

Am J Health Syst Pharm. 2019 Oct 15;76(21):1788-1793. doi: 10.1093/ajhp/zxz191.


Relationship Between Pregnancy-Associated Malaria and Adverse Pregnancy Outcomes: a Systematic Review and Meta-Analysis.

Thompson JM, Eick SM, Dailey C, Dale AP, Mehta M, Nair A, Cordero JF, Welton M.

J Trop Pediatr. 2019 Oct 10. pii: fmz068. doi: 10.1093/tropej/fmz068. [Epub ahead of print]


Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer.

Ma L, Hernandez MO, Zhao Y, Mehta M, Tran B, Kelly M, Rae Z, Hernandez JM, Davis JL, Martin SP, Kleiner DE, Hewitt SM, Ylaya K, Wood BJ, Greten TF, Wang XW.

Cancer Cell. 2019 Oct 14;36(4):418-430.e6. doi: 10.1016/j.ccell.2019.08.007. Epub 2019 Oct 3.


Rapid Eye Movement (REM) Sleep Behavior Disorder and REM Sleep without Atonia in the Young.

Shukla G, Gupta A, Chakravarty K, Joseph AA, Ravindranath A, Mehta M, Gulati S, Kabra M, Mohammed A, Poornima S.

Can J Neurol Sci. 2019 Sep 24:1-9. doi: 10.1017/cjn.2019.302. [Epub ahead of print]


Depression genetic risk score is associated with anhedonia-related markers across units of analysis.

Guffanti G, Kumar P, Admon R, Treadway MT, Hall MH, Mehta M, Douglas S, Arulpragasam AR, Pizzagalli DA.

Transl Psychiatry. 2019 Sep 19;9(1):236. doi: 10.1038/s41398-019-0566-7.


Clinicians' Perceptions of Behavioral Economic Strategies to Increase the Use of Lung-Protective Ventilation.

Mehta M, Veith J, Szymanski S, Madden V, Hart JL, Kerlin MP.

Ann Am Thorac Soc. 2019 Dec;16(12):1543-1549. doi: 10.1513/AnnalsATS.201905-410OC.


Invasive hemodynamic assessment of patients with submassive pulmonary embolism.

Khandhar SJ, Mehta M, Cilia L, Palevsky H, Matthai W, Rivera-Lebron B, Toma C.

Catheter Cardiovasc Interv. 2019 Sep 9. doi: 10.1002/ccd.28491. [Epub ahead of print]


Inducing Mild Traumatic Brain Injury in C. elegans via Cavitation-Free Surface Acoustic Wave-Driven Ultrasonic Irradiation.

Miansari M, Mehta MD, Schilling JM, Kurashina Y, Patel HH, Friend J.

Sci Rep. 2019 Sep 4;9(1):12775. doi: 10.1038/s41598-019-47295-1.


Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201.

Chi AS, Tarapore RS, Hall MD, Shonka N, Gardner S, Umemura Y, Sumrall A, Khatib Z, Mueller S, Kline C, Zaky W, Khatua S, Weathers SP, Odia Y, Niazi TN, Daghistani D, Cherrick I, Korones D, Karajannis MA, Kong XT, Minturn J, Waanders A, Arillaga-Romany I, Batchelor T, Wen PY, Merdinger K, Schalop L, Stogniew M, Allen JE, Oster W, Mehta MP.

J Neurooncol. 2019 Oct;145(1):97-105. doi: 10.1007/s11060-019-03271-3. Epub 2019 Aug 27.


Measurement of neutron induced 86Sr(n, 2n)85Sr reaction cross sections at different neutron energies.

Shetty N, Makwana R, Mehta M, Mukherjee S, Singh NL, Suryanarayana SV, Parashari S, Singh R, Naik H, Sharma SC, Ayyala S, Soni B, Chauhan R.

Appl Radiat Isot. 2019 Dec;154:108866. doi: 10.1016/j.apradiso.2019.108866. Epub 2019 Aug 17.


Splenic biopsy as an unintended consequence of EUS-guided liver biopsy: a cautionary tale.

Diehl DL, Mehta M, Shafqet MA, Confer B, Khan Y, Khara HS, Johal AS.

Gastrointest Endosc. 2019 Aug 20. pii: S0016-5107(19)32144-3. doi: 10.1016/j.gie.2019.08.010. [Epub ahead of print] No abstract available.


Prolonged Duration Local Anesthesia by Combined Delivery of Capsaicin- and Tetrodotoxin-Loaded Liposomes.

Shomorony A, Santamaria CM, Zhao C, Rwei AY, Mehta M, Zurakowski D, Kohane DS.

Anesth Analg. 2019 Sep;129(3):709-717. doi: 10.1213/ANE.0000000000004108.


High potency multistrain probiotic improves liver histology in non-alcoholic fatty liver disease (NAFLD): a randomised, double-blind, proof of concept study.

Duseja A, Acharya SK, Mehta M, Chhabra S; Shalimar, Rana S, Das A, Dattagupta S, Dhiman RK, Chawla YK.

BMJ Open Gastroenterol. 2019 Aug 7;6(1):e000315. doi: 10.1136/bmjgast-2019-000315. eCollection 2019.


Chest Pain and Dyspnea With a Piercing Diagnosis.

Francescon D, Mehta M, Kosier A, Reily R, Boulger C, Prats M, Bahner D.

Chest. 2019 Aug;156(2):e37-e39. doi: 10.1016/j.chest.2019.03.043. No abstract available.


Dynamics of Prolyl Hydroxylases Levels During Disease Progression in Experimental Colitis.

Bakshi HA, Mishra V, Satija S, Mehta M, Hakkim FL, Kesharwani P, Dua K, Chellappan DK, Charbe NB, Shrivastava G, Rajeshkumar S, Aljabali AA, Al-Trad B, Pabreja K, Tambuwala MM.

Inflammation. 2019 Dec;42(6):2032-2036. doi: 10.1007/s10753-019-01065-3.


Subjective sleep problems and sleep hygiene among adolescents having depression: A case-control study.

Gupta P, Sagar R, Mehta M.

Asian J Psychiatr. 2019 Aug;44:150-155. doi: 10.1016/j.ajp.2019.07.034. Epub 2019 Jul 24.


The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

R Andrade P, Mehta M, Lu J, M B Teles R, Montoya D, O Scumpia P, Nunes Sarno E, Ochoa MT, Ma F, Pellegrini M, Modlin RL.

PLoS Negl Trop Dis. 2019 Jul 25;13(7):e0007589. doi: 10.1371/journal.pntd.0007589. eCollection 2019 Jul.


Estimating survival in patients with gastrointestinal cancers and brain metastases: An update of the graded prognostic assessment for gastrointestinal cancers (GI-GPA).

Sperduto PW, Fang P, Li J, Breen W, Brown PD, Cagney D, Aizer A, Yu JB, Chiang V, Jain S, Gaspar LE, Myrehaug S, Sahgal A, Braunstein S, Sneed P, Cameron B, Attia A, Molitoris J, Wu CC, Wang TJC, Lockney NA, Beal K, Parkhurst J, Buatti JM, Shanley R, Lou E, Tandberg DD, Kirkpatrick JP, Shi D, Shih HA, Chuong M, Saito H, Aoyama H, Masucci L, Roberge D, Mehta MP.

Clin Transl Radiat Oncol. 2019 Jun 27;18:39-45. doi: 10.1016/j.ctro.2019.06.007. eCollection 2019 Sep.


Recent Developments in Alpha-Glucosidase Inhibitors for Management of Type-2 Diabetes: An Update.

Usman B, Sharma N, Satija S, Mehta M, Vyas M, Khatik GL, Khurana N, Hansbro PM, Williams K, Dua K.

Curr Pharm Des. 2019;25(23):2510-2525. doi: 10.2174/1381612825666190717104547.


Base-Mediated Meerwein-Ponndorf-Verley Reduction of Aromatic and Heterocyclic Ketones.

Boit TB, Mehta MM, Garg NK.

Org Lett. 2019 Aug 16;21(16):6447-6451. doi: 10.1021/acs.orglett.9b02342. Epub 2019 Jul 22.


Topical sustained drug delivery to the retina with a drug-eluting contact lens.

Ross AE, Bengani LC, Tulsan R, Maidana DE, Salvador-Culla B, Kobashi H, Kolovou PE, Zhai H, Taghizadeh K, Kuang L, Mehta M, Vavvas DG, Kohane DS, Ciolino JB.

Biomaterials. 2019 Oct;217:119285. doi: 10.1016/j.biomaterials.2019.119285. Epub 2019 Jun 21.


Epidermal growth factor receptor (EGFR) amplification rates observed in screening patients for randomized trials in glioblastoma.

Lassman AB, Aldape KD, Ansell PJ, Bain E, Curran WJ, Eoli M, French PJ, Kinoshita M, Looman J, Mehta M, Muragaki Y, Narita Y, Ocampo C, Roberts-Rapp L, Song M, Vogelbaum MA, Walenkamp AME, Wang TJC, Zhang P, van den Bent MJ.

J Neurooncol. 2019 Aug;144(1):205-210. doi: 10.1007/s11060-019-03222-y. Epub 2019 Jul 4.


An update on the animal studies conducted for biosimilar approvals - Regulatory requirement vs actual scenario.

Pipalava P, Patel R, Mehta M, Dahiya M, Singh I, Jose V.

Regul Toxicol Pharmacol. 2019 Oct;107:104415. doi: 10.1016/j.yrtph.2019.104415. Epub 2019 Jun 26. Review.


Emerging trends in the novel drug delivery approaches for the treatment of lung cancer.

Sharma P, Mehta M, Dhanjal DS, Kaur S, Gupta G, Singh H, Thangavelu L, Rajeshkumar S, Tambuwala M, Bakshi HA, Chellappan DK, Dua K, Satija S.

Chem Biol Interact. 2019 Aug 25;309:108720. doi: 10.1016/j.cbi.2019.06.033. Epub 2019 Jun 18. Review.


Letter: When Less is More: Dexamethasone Dosing for Brain Tumors.

Lim-Fat MJ, Bi WL, Lo J, Lee EQ, Ahluwalia MS, Batchelor TT, Chang SM, Chiocca EA, Chukwueke U, Cloughesy TF, Colman H, Deangelis LM, Galanis E, Gilbert MR, De Groot JF, Lassman AB, Liau LM, Mason W, McFaline-Figueroa JR, Mehta MP, Mellinghoff IK, Nabors LB, Nayak L, Reardon DA, Wen PY.

Neurosurgery. 2019 Sep 1;85(3):E607-E608. doi: 10.1093/neuros/nyz186. No abstract available.


Antibacterial and antioxidant potential of biosynthesized copper nanoparticles mediated through Cissus arnotiana plant extract.

Rajeshkumar S, Menon S, Venkat Kumar S, Tambuwala MM, Bakshi HA, Mehta M, Satija S, Gupta G, Chellappan DK, Thangavelu L, Dua K.

J Photochem Photobiol B. 2019 Aug;197:111531. doi: 10.1016/j.jphotobiol.2019.111531. Epub 2019 Jun 6.


Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity.

Zhao C, Liu A, Santamaria CM, Shomorony A, Ji T, Wei T, Gordon A, Elofsson H, Mehta M, Yang R, Kohane DS.

Nat Commun. 2019 Jun 12;10(1):2566. doi: 10.1038/s41467-019-10296-9.

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