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Items: 1 to 50 of 54

1.

Toward a Synthetic Yeast Endosymbiont with a Minimal Genome.

Mehta AP, Ko Y, Supekova L, Pestonjamasp K, Li J, Schultz PG.

J Am Chem Soc. 2019 Sep 4;141(35):13799-13802. doi: 10.1021/jacs.9b08290. Epub 2019 Aug 26.

PMID:
31419116
2.

Bilateral Medullary Nephrocalcinosis Secondary to Vitamin D Toxicity: A 14-year Follow-up Report.

Goyal A, Rahaman SH, Raizada N, Kandasamy D, Mehta AP, Khadgawat R.

Indian J Endocrinol Metab. 2018 Nov-Dec;22(6):853-854. doi: 10.4103/ijem.IJEM_588_18. No abstract available.

3.

Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids.

Li JC, Liu T, Wang Y, Mehta AP, Schultz PG.

J Am Chem Soc. 2018 Nov 28;140(47):15997-16000. doi: 10.1021/jacs.8b07157. Epub 2018 Nov 15.

4.

Engineering yeast endosymbionts as a step toward the evolution of mitochondria.

Mehta AP, Supekova L, Chen JH, Pestonjamasp K, Webster P, Ko Y, Henderson SC, McDermott G, Supek F, Schultz PG.

Proc Natl Acad Sci U S A. 2018 Nov 13;115(46):11796-11801. doi: 10.1073/pnas.1813143115. Epub 2018 Oct 29.

5.

An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12.

Gagnon DM, Stich TA, Mehta AP, Abdelwahed SH, Begley TP, Britt RD.

J Am Chem Soc. 2018 Oct 10;140(40):12798-12807. doi: 10.1021/jacs.8b05686. Epub 2018 Sep 27.

6.

Bacterial Genome Containing Chimeric DNA-RNA Sequences.

Mehta AP, Wang Y, Reed SA, Supekova L, Javahishvili T, Chaput JC, Schultz PG.

J Am Chem Soc. 2018 Sep 12;140(36):11464-11473. doi: 10.1021/jacs.8b07046. Epub 2018 Aug 30.

PMID:
30160955
7.

Progress toward a reduced phage genetic code.

Yao A, Reed SA, Koh M, Yu C, Luo X, Mehta AP, Schultz PG.

Bioorg Med Chem. 2018 Oct 15;26(19):5247-5252. doi: 10.1016/j.bmc.2018.03.035. Epub 2018 Mar 26.

PMID:
29609949
8.

Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids.

Zambaldo C, Luo X, Mehta AP, Schultz PG.

J Am Chem Soc. 2017 Aug 30;139(34):11646-11649. doi: 10.1021/jacs.7b04159. Epub 2017 Aug 15.

9.

Replacement of 2'-Deoxycytidine by 2'-Deoxycytidine Analogues in the E. coli Genome.

Mehta AP, Li H, Reed SA, Supekova L, Javahishvili T, Schultz PG.

J Am Chem Soc. 2016 Nov 2;138(43):14230-14233. Epub 2016 Oct 20.

10.

Identification of the First Riboflavin Catabolic Gene Cluster Isolated from Microbacterium maritypicum G10.

Xu H, Chakrabarty Y, Philmus B, Mehta AP, Bhandari D, Hohmann HP, Begley TP.

J Biol Chem. 2016 Nov 4;291(45):23506-23515. Epub 2016 Sep 2.

11.

Replacement of Thymidine by a Modified Base in the Escherichia coli Genome.

Mehta AP, Li H, Reed SA, Supekova L, Javahishvili T, Schultz PG.

J Am Chem Soc. 2016 Jun 15;138(23):7272-5. doi: 10.1021/jacs.6b03904. Epub 2016 Jun 3.

12.

Anaerobic biosynthesis of the lower ligand of vitamin B12.

Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10792-7. doi: 10.1073/pnas.1509132112. Epub 2015 Aug 5.

13.

Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.

Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP.

J Am Chem Soc. 2015 Aug 26;137(33):10444-7. doi: 10.1021/jacs.5b03576. Epub 2015 Aug 13.

14.

Molybdopterin biosynthesis-Mechanistic studies on a novel MoaA catalyzed insertion of a purine carbon into the ribose of GTP.

Mehta AP, Abdelwahed SH, Begley TP.

Biochim Biophys Acta. 2015 Sep;1854(9):1073-7. doi: 10.1016/j.bbapap.2015.04.008. Epub 2015 Apr 17. Review.

15.

Non-canonical active site architecture of the radical SAM thiamin pyrimidine synthase.

Fenwick MK, Mehta AP, Zhang Y, Abdelwahed SH, Begley TP, Ealick SE.

Nat Commun. 2015 Mar 27;6:6480. doi: 10.1038/ncomms7480.

16.

Radical S-adenosylmethionine (SAM) enzymes in cofactor biosynthesis: a treasure trove of complex organic radical rearrangement reactions.

Mehta AP, Abdelwahed SH, Mahanta N, Fedoseyenko D, Philmus B, Cooper LE, Liu Y, Jhulki I, Ealick SE, Begley TP.

J Biol Chem. 2015 Feb 13;290(7):3980-6. doi: 10.1074/jbc.R114.623793. Epub 2014 Dec 4. Review.

17.

Molybdopterin biosynthesis: trapping of intermediates for the MoaA-catalyzed reaction using 2'-deoxyGTP and 2'-chloroGTP as substrate analogues.

Mehta AP, Abdelwahed SH, Xu H, Begley TP.

J Am Chem Soc. 2014 Jul 30;136(30):10609-14. doi: 10.1021/ja502663k. Epub 2014 Jul 18.

18.

Molybdopterin biosynthesis: trapping an unusual purine ribose adduct in the MoaA-catalyzed reaction.

Mehta AP, Abdelwahed SH, Begley TP.

J Am Chem Soc. 2013 Jul 31;135(30):10883-5. doi: 10.1021/ja4041048. Epub 2013 Jul 22.

19.

Formulation and optimisation of raft-forming chewable tablets containing H2 antagonist.

Prajapati ST, Mehta AP, Modhia IP, Patel CN.

Int J Pharm Investig. 2012 Oct;2(4):176-82. doi: 10.4103/2230-973X.106988.

20.

Catalysis of a new ribose carbon-insertion reaction by the molybdenum cofactor biosynthetic enzyme MoaA.

Mehta AP, Hanes JW, Abdelwahed SH, Hilmey DG, Hänzelmann P, Begley TP.

Biochemistry. 2013 Feb 19;52(7):1134-6. doi: 10.1021/bi3016026. Epub 2013 Feb 4.

21.

The neglected and often ignored: nontuberculous mycobacteria.

Jani MN, Rodrigues CS, Mehta AP.

J Glob Infect Dis. 2011 Jan;3(1):94. doi: 10.4103/0974-777X.77305. No abstract available.

22.

Frozen state storage instability of a monoclonal antibody: aggregation as a consequence of trehalose crystallization and protein unfolding.

Singh SK, Kolhe P, Mehta AP, Chico SC, Lary AL, Huang M.

Pharm Res. 2011 Apr;28(4):873-85. doi: 10.1007/s11095-010-0343-z. Epub 2011 Jan 7.

PMID:
21213025
23.

Prospective comparison of eubacterial PCR and measurement of procalcitonin levels with blood culture for diagnosing septicemia in intensive care unit patients.

Rowther FB, Rodrigues CS, Deshmukh MS, Kapadia FN, Hegde A, Mehta AP, Joshi VR.

J Clin Microbiol. 2009 Sep;47(9):2964-9. doi: 10.1128/JCM.00418-07. Epub 2009 Jul 29.

24.

Rapid detection of rifampicin resistance in M. tuberculosis by phage assay.

Krishnamurthy A, Rodrigues C, Mehta AP.

Indian J Med Microbiol. 2002 Oct-Dec;20(4):211-4.

25.

Evaluation of a new phage amplification technology for rapid diagnosis of tuberculosis.

Shenai S, Rodrigues C, Mehta AP.

Indian J Med Microbiol. 2002 Oct-Dec;20(4):194-9.

26.

Use of bactec 460 TB system in the diagnosis of tuberculosis.

Rodrigues CS, Shenai SV, Almeida D, Sadani MA, Goyal N, Vadher C, Mehta AP.

Indian J Med Microbiol. 2007 Jan;25(1):32-6.

27.

Acute vitamin d toxicity in an infant.

Khadgawat R, Goswami R, Gupta N, Seith A, Mehta AP.

Clin Pediatr Endocrinol. 2007;16(4):89-93. doi: 10.1297/cpe.16.89. Epub 2007 Nov 17.

28.

Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma.

Yin CC, Medeiros LJ, Cromwell CC, Mehta AP, Lin P, Luthra R, Abruzzo LV.

Mod Pathol. 2007 Jan;20(1):1-7. Epub 2006 Oct 20.

29.

Universal mean moment rate profiles of earthquake ruptures.

Mehta AP, Dahmen KA, Ben-Zion Y.

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 May;73(5 Pt 2):056104. Epub 2006 May 5.

PMID:
16802995
30.

Anti-tumor necrosis factor therapy is tolerated in an individual with homozygous complement C2 deficiency.

Momeni M, Mehta AP, Katz JD.

J Clin Rheumatol. 2005 Jun;11(3):180-2. No abstract available.

PMID:
16357744
31.

An improved method of elimination of DNA from PCR reagents.

Rowther FB, Rodrigues C, Mehta AP, Deshmukh MS, Kapadia FN, Hegde A, Joshi VR.

Mol Diagn. 2005;9(2):53-7.

PMID:
16137180
32.

Comparing serology, antigenemia assay and polymerase chain reaction for the diagnosis of cytomegalovirus infection in renal transplant patients.

Bhatia J, Shah BV, Mehta AP, Deshmukh M, Sirsat RA, Rodrigues C.

J Assoc Physicians India. 2004 Apr;52:297-300.

PMID:
15636331
33.

Orbital myositis associated with Borrelia burgdorferi (Lyme disease) infection.

Carvounis PE, Mehta AP, Geist CE.

Ophthalmology. 2004 May;111(5):1023-8.

PMID:
15121383
34.

Universal pulse shape scaling function and exponents: critical test for avalanche models applied to Barkhausen noise.

Mehta AP, Mills AC, Dahmen KA, Sethna JP.

Phys Rev E Stat Nonlin Soft Matter Phys. 2002 Apr;65(4 Pt 2A):046139. Epub 2002 Apr 10.

PMID:
12005958
35.

Neuron-enriched second trimester human cultures: growth factor response and in vivo graft survival.

White MG, Hammond RR, Sanders VJ, Bonaroti EA, Mehta AP, Wang G, Wiley CA, Achim CL.

Cell Transplant. 1999 Jan-Feb;8(1):59-73.

PMID:
10338276
36.

A murine model of HIV encephalitis: xenotransplantation of HIV-infected human neuroglia into SCID mouse brain.

Sanders VJ, Mehta AP, White MG, Achim CL.

Neuropathol Appl Neurobiol. 1998 Dec;24(6):461-7.

PMID:
9888156
37.

Comparison of FK-506, rapamycin, ascomycin, and cyclosporine in mouse models of host-versus-graft disease and heterotopic heart transplantation.

Mollison KW, Fey TA, Krause RA, Thomas VA, Mehta AP, Luly JR.

Ann N Y Acad Sci. 1993 Jun 23;685:55-7. No abstract available.

PMID:
7689812
38.

Comparative study of amoxycillin and amoxycillin/clavulanic acid in lower respiratory infections.

Mehta AP, Phutane L, Patel MH, Rupwate RU, Kamat SR.

J Assoc Physicians India. 1991 Mar;39(3):251-3.

PMID:
1880092
39.

Lactobacillus acidophilus inhibits growth of Campylobacter pylori in vitro.

Bhatia SJ, Kochar N, Abraham P, Nair NG, Mehta AP.

J Clin Microbiol. 1989 Oct;27(10):2328-30.

40.

Role of microbial study in selection of subjects for in vitro fertilization & embryo transfer (IVF-ET).

Gopalkrishnan K, Hinduja IN, Latha P, Mehta AP.

Indian J Med Res. 1988 Aug;88:141-5. No abstract available.

PMID:
3198172
41.

Therapeutic efficacy and tolerability of cefotaxime--a study of acute respiratory infections in chronic lung conditions.

Shah SP, Mehta AP, Shetty SR, Mahashur AA, Kamat SR.

J Postgrad Med. 1988 Jan;34(1):15-20. No abstract available.

PMID:
3385652
42.

Surgery for the community in the community.

Kowli SS, Parikh SK, Chaturvedi RM, Nayak M, Kowli SS, Mehta AP, Bhalerao VR, Bhalerao RA.

J Postgrad Med. 1985 Jan;31(1):16-9. No abstract available.

43.

Incidence of gonorrhoea in leucorrhoea cases.

Deshmukh MA, Mehta AP, Dabholkar KM, Bojari MR, Talwalkar JM.

J Postgrad Med. 1985 Jan;31(1):39-42. No abstract available.

44.

The role of iron in metal sulfide leaching by galvanic interaction.

Murr LE, Mehta AP.

Biotechnol Bioeng. 1983 Apr;25(4):1175-9. No abstract available.

PMID:
18548729
45.

A comparative study of various antibacterial drugs in lower respiratory tract infections and pneumonias in adults.

Kamat SR, Mehta AP, Doshi VB, Walimbe S, Jayakar VV, Mahashur AA.

J Assoc Physicians India. 1983 Apr;31(4):209-15. No abstract available.

PMID:
6643381
46.

Coal desulfurization by leaching involving acidophilic and thermophilic microorganisms.

Murr LE, Mehta AP.

Biotechnol Bioeng. 1982 Oct;24(10):2293. No abstract available.

PMID:
18546140
48.

Coal desulfurization by leaching involving acidophilic and thermophilic microorganisms.

Murr LE, Mehta AP.

Biotechnol Bioeng. 1982 Mar;24(3):743-8. No abstract available.

PMID:
18546361
49.

Disseminated systemic mucormycosis. (A case report).

Kamat SR, Shah SP, Mahashur AA, Shah DC, Mehta AP.

J Postgrad Med. 1982;28(4):229-32. No abstract available.

50.

Acute amoebic dysentery due to free-living amoebae treated with methronidazole.

Mehta AP, Guirges SY.

J Trop Med Hyg. 1979 Jul;82(7):134-6.

PMID:
501769

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