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Items: 19


Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants.

Lai H, He J, Hurtado J, Stahnke J, Fuchs A, Mehlhop E, Gorlatov S, Loos A, Diamond MS, Chen Q.

Plant Biotechnol J. 2014 Oct;12(8):1098-107. doi: 10.1111/pbi.12217. Epub 2014 Jun 29.


Enhancement of anti-DIII antibodies by the C3d derivative P28 results in lower viral titers and augments protection in mice.

Dunn MD, Rossi SL, Carter DM, Vogt MR, Mehlhop E, Diamond MS, Ross TM.

Virol J. 2010 May 12;7:95. doi: 10.1186/1743-422X-7-95.


Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification.

Balsitis SJ, Williams KL, Lachica R, Flores D, Kyle JL, Mehlhop E, Johnson S, Diamond MS, Beatty PR, Harris E.

PLoS Pathog. 2010 Feb 12;6(2):e1000790. doi: 10.1371/journal.ppat.1000790.


Complement protein C1q reduces the stoichiometric threshold for antibody-mediated neutralization of West Nile virus.

Mehlhop E, Nelson S, Jost CA, Gorlatov S, Johnson S, Fremont DH, Diamond MS, Pierson TC.

Cell Host Microbe. 2009 Oct 22;6(4):381-91. doi: 10.1016/j.chom.2009.09.003.


Complement modulates pathogenesis and antibody-dependent neutralization of West Nile virus infection through a C5-independent mechanism.

Mehlhop E, Fuchs A, Engle M, Diamond MS.

Virology. 2009 Oct 10;393(1):11-5. doi: 10.1016/j.virol.2009.08.019. Epub 2009 Sep 9.


Complement and its role in protection and pathogenesis of flavivirus infections.

Avirutnan P, Mehlhop E, Diamond MS.

Vaccine. 2008 Dec 30;26 Suppl 8:I100-7. Review.


The host immunologic response to West Nile encephalitis virus.

Diamond MS, Mehlhop E, Oliphant T, Samuel MA.

Front Biosci (Landmark Ed). 2009 Jan 1;14:3024-34. Review.


Complement protein C1q inhibits antibody-dependent enhancement of flavivirus infection in an IgG subclass-specific manner.

Mehlhop E, Ansarah-Sobrinho C, Johnson S, Engle M, Fremont DH, Pierson TC, Diamond MS.

Cell Host Microbe. 2007 Dec 13;2(6):417-26.


The molecular basis of antibody protection against West Nile virus.

Mehlhop E, Diamond MS.

Curr Top Microbiol Immunol. 2008;317:125-53. Review.


Protective immune responses against West Nile virus are primed by distinct complement activation pathways.

Mehlhop E, Diamond MS.

J Exp Med. 2006 May 15;203(5):1371-81. Epub 2006 May 1.


Complement activation is required for induction of a protective antibody response against West Nile virus infection.

Mehlhop E, Whitby K, Oliphant T, Marri A, Engle M, Diamond MS.

J Virol. 2005 Jun;79(12):7466-77.


Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus.

Oliphant T, Engle M, Nybakken GE, Doane C, Johnson S, Huang L, Gorlatov S, Mehlhop E, Marri A, Chung KM, Ebel GD, Kramer LD, Fremont DH, Diamond MS.

Nat Med. 2005 May;11(5):522-30. Epub 2005 Apr 24.


Macaque dendritic cells infected with SIV-recombinant canarypox ex vivo induce SIV-specific immune responses in vivo.

Villamide-Herrera L, Ignatius R, Eller MA, Wilkinson K, Griffin C, Mehlhop E, Jones J, Han SY, Lewis MG, Parrish S, Vancott TC, Lifson JD, Schlesinger S, Mascola JR, Pope M.

AIDS Res Hum Retroviruses. 2004 Aug;20(8):871-84.


Innate and adaptive immune responses determine protection against disseminated infection by West Nile encephalitis virus.

Diamond MS, Shrestha B, Mehlhop E, Sitati E, Engle M.

Viral Immunol. 2003;16(3):259-78. Review.


Presentation of exogenous whole inactivated simian immunodeficiency virus by mature dendritic cells induces CD4+ and CD8+ T-cell responses.

Frank I, Santos JJ, Mehlhop E, Villamide-Herrera L, Santisteban C, Gettie A, Ignatius R, Lifson JD, Pope M.

J Acquir Immune Defic Syndr. 2003 Sep 1;34(1):7-19.


Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.

Messmer D, JacquƩ JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M.

J Immunol. 2002 Oct 15;169(8):4172-82.


Rhesus macaque dendritic cells efficiently transmit primate lentiviruses independently of DC-SIGN.

Wu L, Bashirova AA, Martin TD, Villamide L, Mehlhop E, Chertov AO, Unutmaz D, Pope M, Carrington M, KewalRamani VN.

Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1568-73. Epub 2002 Jan 29.


Enhanced in vitro stimulation of rhesus macaque dendritic cells for activation of SIV-specific T cell responses.

Mehlhop E, Villamide LA, Frank I, Gettie A, Santisteban C, Messmer D, Ignatius R, Lifson JD, Pope M.

J Immunol Methods. 2002 Feb 1;260(1-2):219-34.


Canarypox virus-induced maturation of dendritic cells is mediated by apoptotic cell death and tumor necrosis factor alpha secretion.

Ignatius R, Marovich M, Mehlhop E, Villamide L, Mahnke K, Cox WI, Isdell F, Frankel SS, Mascola JR, Steinman RM, Pope M.

J Virol. 2000 Dec;74(23):11329-38.

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