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Items: 5


Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity.

Kleiner S, Gomez D, Megra B, Na E, Bhavsar R, Cavino K, Xin Y, Rojas J, Dominguez-Gutierrez G, Zambrowicz B, Carrat G, Chabosseau P, Hu M, Murphy AJ, Yancopoulos GD, Rutter GA, Gromada J.

Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):E7642-E7649. doi: 10.1073/pnas.1721418115. Epub 2018 Jul 23.


Inflammatory mediators reduce surface PrPc on human BMVEC resulting in decreased barrier integrity.

Megra BW, Eugenin EA, Berman JW.

Lab Invest. 2018 Oct;98(10):1347-1359. doi: 10.1038/s41374-018-0090-z. Epub 2018 Jun 29.


The Role of Shed PrPc in the Neuropathogenesis of HIV Infection.

Megra BW, Eugenin EA, Berman JW.

J Immunol. 2017 Jul 1;199(1):224-232. doi: 10.4049/jimmunol.1601041. Epub 2017 May 22.


Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.

Dickens AM, Tovar-Y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ.

Sci Signal. 2017 Apr 4;10(473). pii: eaai7696. doi: 10.1126/scisignal.aai7696.


Protease resistant protein cellular isoform (PrP(c)) as a biomarker: clues into the pathogenesis of HAND.

Megra B, Eugenin E, Roberts T, Morgello S, Berman JW.

J Neuroimmune Pharmacol. 2013 Dec;8(5):1159-66. doi: 10.1007/s11481-013-9458-4. Epub 2013 Apr 25. Review.

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