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Items: 1 to 50 of 90


Molecular basis for fluidization of cancer cells.

Mège RM.

Nat Mater. 2019 Nov;18(11):1147-1148. doi: 10.1038/s41563-019-0521-2. No abstract available.


Myosin II isoforms play distinct roles in adherens junction biogenesis.

Heuzé ML, Sankara Narayana GHN, D'Alessandro J, Cellerin V, Dang T, Williams DS, Van Hest JC, Marcq P, Mège RM, Ladoux B.

Elife. 2019 Sep 5;8. pii: e46599. doi: 10.7554/eLife.46599.


Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk.

Nguyen T, Duchesne L, Sankara Narayana GHN, Boggetto N, Fernig DD, Uttamrao Murade C, Ladoux B, Mège RM.

Oncogene. 2019 Aug;38(35):6283-6300. doi: 10.1038/s41388-019-0875-6. Epub 2019 Jul 16.


Sustained Oscillations of Epithelial Cell Sheets.

Peyret G, Mueller R, d'Alessandro J, Begnaud S, Marcq P, Mège RM, Yeomans JM, Doostmohammadi A, Ladoux B.

Biophys J. 2019 Aug 6;117(3):464-478. doi: 10.1016/j.bpj.2019.06.013. Epub 2019 Jul 2.


Influence of proliferation on the motions of epithelial monolayers invading adherent strips.

Gauquelin E, Tlili S, Gay C, Peyret G, Mège RM, Fardin MA, Ladoux B.

Soft Matter. 2019 Apr 7;15(13):2798-2810. doi: 10.1039/c9sm00105k. Epub 2019 Mar 19.


Cell shape and substrate stiffness drive actin-based cell polarity.

Gupta M, Doss BL, Kocgozlu L, Pan M, Mège RM, Callan-Jones A, Voituriez R, Ladoux B.

Phys Rev E. 2019 Jan;99(1-1):012412. doi: 10.1103/PhysRevE.99.012412.


Positive cystic duct margin at index cholecystectomy in incidental gallbladder cancer is an important negative prognosticator.

Vega EA, Vinuela E, Sanhueza M, Mege R, Caracci M, Diaz C, Diaz A, Okuno M, Joechle K, Goumard C, Chun YS, Tzeng CD, Lee JE, Vauthey JN, Conrad C.

Eur J Surg Oncol. 2019 Jun;45(6):1061-1068. doi: 10.1016/j.ejso.2019.01.013. Epub 2019 Jan 24.


Mechanical forces in cell monolayers.

Chen T, Saw TB, Mège RM, Ladoux B.

J Cell Sci. 2018 Dec 20;131(24). pii: jcs218156. doi: 10.1242/jcs.218156. Review.


[The irruption of mechanics in the chemistry of life].

Mège RM, Ladoux B.

Med Sci (Paris). 2018 Nov;34(11):963-971. doi: 10.1051/medsci/2018241. Epub 2018 Dec 10. Review. French.


Force-dependent binding of vinculin to α-catenin regulates cell-cell contact stability and collective cell behavior.

Seddiki R, Narayana GHNS, Strale PO, Balcioglu HE, Peyret G, Yao M, Le AP, Teck Lim C, Yan J, Ladoux B, Mège RM.

Mol Biol Cell. 2018 Feb 15;29(4):380-388. doi: 10.1091/mbc.E17-04-0231. Epub 2017 Dec 27.


Mechanobiology of collective cell behaviours.

Ladoux B, Mège RM.

Nat Rev Mol Cell Biol. 2017 Dec;18(12):743-757. doi: 10.1038/nrm.2017.98. Epub 2017 Nov 8. Review.


Incidental Gallbladder Cancer: Residual Cancer Discovered at Oncologic Extended Resection Determines Outcome: A Report from High- and Low-Incidence Countries.

Vinuela E, Vega EA, Yamashita S, Sanhueza M, Mege R, Cavada G, Aloia TA, Chun YS, Lee JE, Vauthey JN, Conrad C.

Ann Surg Oncol. 2017 Aug;24(8):2334-2343. doi: 10.1245/s10434-017-5859-6. Epub 2017 Apr 17.


Why would you like to publish in Biology of the Cell.

Mège RM.

Biol Cell. 2017 Mar;109(3):113-114. doi: 10.1111/boc.201770010. No abstract available.


Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.

Mège RM, Ishiyama N.

Cold Spring Harb Perspect Biol. 2017 May 1;9(5). pii: a028738. doi: 10.1101/cshperspect.a028738. Review.


Nanoscale architecture of cadherin-based cell adhesions.

Bertocchi C, Wang Y, Ravasio A, Hara Y, Wu Y, Sailov T, Baird MA, Davidson MW, Zaidel-Bar R, Toyama Y, Ladoux B, Mege RM, Kanchanawong P.

Nat Cell Biol. 2017 Jan;19(1):28-37. doi: 10.1038/ncb3456. Epub 2016 Dec 19.


Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics.

Sarangi BR, Gupta M, Doss BL, Tissot N, Lam F, Mège RM, Borghi N, Ladoux B.

Nano Lett. 2017 Jan 11;17(1):399-406. doi: 10.1021/acs.nanolett.6b04364. Epub 2016 Dec 23.


A phenomenological model of cell-cell adhesion mediated by cadherins.

Mancini S, Mège RM, Sarels B, Strale PO.

J Math Biol. 2017 Jun;74(7):1657-1678. doi: 10.1007/s00285-016-1072-7. Epub 2016 Oct 25.


Epithelial Cell Packing Induces Distinct Modes of Cell Extrusions.

Kocgozlu L, Saw TB, Le AP, Yow I, Shagirov M, Wong E, Mège RM, Lim CT, Toyama Y, Ladoux B.

Curr Biol. 2016 Nov 7;26(21):2942-2950. doi: 10.1016/j.cub.2016.08.057. Epub 2016 Oct 13.


N-Cadherin and Fibroblast Growth Factor Receptors crosstalk in the control of developmental and cancer cell migrations.

Nguyen T, Mège RM.

Eur J Cell Biol. 2016 Nov;95(11):415-426. doi: 10.1016/j.ejcb.2016.05.002. Epub 2016 Jun 6. Review.


Mechanics of epithelial tissues during gap closure.

Begnaud S, Chen T, Delacour D, Mège RM, Ladoux B.

Curr Opin Cell Biol. 2016 Oct;42:52-62. doi: 10.1016/ Epub 2016 Apr 28. Review.


Remodeling the zonula adherens in response to tension and the role of afadin in this response.

Choi W, Acharya BR, Peyret G, Fardin MA, Mège RM, Ladoux B, Yap AS, Fanning AS, Peifer M.

J Cell Biol. 2016 Apr 25;213(2):243-60. doi: 10.1083/jcb.201506115.


Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.

Ladoux B, Mège RM, Trepat X.

Trends Cell Biol. 2016 Jun;26(6):420-433. doi: 10.1016/j.tcb.2016.02.002. Epub 2016 Feb 23. Review.


Regulation of epithelial cell organization by tuning cell-substrate adhesion.

Ravasio A, Le AP, Saw TB, Tarle V, Ong HT, Bertocchi C, Mège RM, Lim CT, Gov NS, Ladoux B.

Integr Biol (Camb). 2015 Oct;7(10):1228-41. doi: 10.1039/c5ib00196j. Epub 2015 Sep 24.


The formation of ordered nanoclusters controls cadherin anchoring to actin and cell-cell contact fluidity.

Strale PO, Duchesne L, Peyret G, Montel L, Nguyen T, Png E, Tampé R, Troyanovsky S, Hénon S, Ladoux B, Mège RM.

J Cell Biol. 2015 Sep 14;210(6):1033. doi: 10.1083/jcb.20141011109022015c. No abstract available.


The formation of ordered nanoclusters controls cadherin anchoring to actin and cell-cell contact fluidity.

Strale PO, Duchesne L, Peyret G, Montel L, Nguyen T, Png E, Tampé R, Troyanovsky S, Hénon S, Ladoux B, Mège RM.

J Cell Biol. 2015 Jul 20;210(2):333-46. doi: 10.1083/jcb.201410111. Erratum in: J Cell Biol. 2015 Sep 14;210(6):1033.


Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing.

Gupta M, Sarangi BR, Deschamps J, Nematbakhsh Y, Callan-Jones A, Margadant F, Mège RM, Lim CT, Voituriez R, Ladoux B.

Nat Commun. 2015 Jun 25;6:7525. doi: 10.1038/ncomms8525.


The mechanotransduction machinery at work at adherens junctions.

Ladoux B, Nelson WJ, Yan J, Mège RM.

Integr Biol (Camb). 2015 Oct;7(10):1109-19. doi: 10.1039/c5ib00070j. Epub 2015 May 13. Review.


Corrigendum: Force-dependent conformational switch of α-catenin controls vinculin binding.

Yao M, Qiu W, Liu R, Efremov AK, Cong P, Seddiki R, Payre M, Lim CT, Ladoux B, Mège RM, Yan J.

Nat Commun. 2015 Mar 4;6:6568. doi: 10.1038/ncomms7568. No abstract available.


Force-dependent conformational switch of α-catenin controls vinculin binding.

Yao M, Qiu W, Liu R, Efremov AK, Cong P, Seddiki R, Payre M, Lim CT, Ladoux B, Mège RM, Yan J.

Nat Commun. 2014 Jul 31;5:4525. doi: 10.1038/ncomms5525. Erratum in: Nat Commun. 2015;6:6568.


Adhesive interactions of N-cadherin limit the recruitment of microtubules to cell-cell contacts through organization of actomyosin.

Plestant C, Strale PO, Seddiki R, Nguyen E, Ladoux B, Mège RM.

J Cell Sci. 2014 Apr 15;127(Pt 8):1660-71. doi: 10.1242/jcs.131284. Epub 2014 Feb 12.


[Gastric lipoma removed by laparoscopic subtotal gastrectomy: report of one case].

Olguín R R, Norero M E, Briceño E, Martínez C, Viñuela E, Báez S, Aguayo G, Calvo A, Mege R R, Díaz A.

Rev Med Chil. 2013 Jul;141(7):927-31. doi: 10.4067/S0034-98872013000700014. Spanish.


N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration.

Luccardini C, Hennekinne L, Viou L, Yanagida M, Murakami F, Kessaris N, Ma X, Adelstein RS, Mège RM, Métin C.

J Neurosci. 2013 Nov 13;33(46):18149-60. doi: 10.1523/JNEUROSCI.0593-13.2013.


α-catenin, vinculin, and F-actin in strengthening E-cadherin cell-cell adhesions and mechanosensing.

Dufour S, Mège RM, Thiery JP.

Cell Adh Migr. 2013 Jul-Aug;7(4):345-50. doi: 10.4161/cam.25139. Epub 2013 Jun 5.


α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strength.

Thomas WA, Boscher C, Chu YS, Cuvelier D, Martinez-Rico C, Seddiki R, Heysch J, Ladoux B, Thiery JP, Mege RM, Dufour S.

J Biol Chem. 2013 Feb 15;288(7):4957-69. doi: 10.1074/jbc.M112.403774. Epub 2012 Dec 24.


N-cadherin mediates neuronal cell survival through Bim down-regulation.

Lelièvre EC, Plestant C, Boscher C, Wolff E, Mège RM, Birbes H.

PLoS One. 2012;7(3):e33206. doi: 10.1371/journal.pone.0033206. Epub 2012 Mar 12.


[Results of pancreaticoduodenectomy in the treatment of periampullary tumors].

Norero E, Viñuela E, Báez S, Martínez C, Reyes J, Kusanovic R, Sanhueza M, Aguayo G, Calvo A, Mege RM, Caracci M, Díaz A.

Rev Med Chil. 2011 Aug;139(8):1015-24. doi: /S0034-98872011000800006. Epub 2011 Dec 20. Spanish.


Strength dependence of cadherin-mediated adhesions.

Ladoux B, Anon E, Lambert M, Rabodzey A, Hersen P, Buguin A, Silberzan P, Mège RM.

Biophys J. 2010 Feb 17;98(4):534-42. doi: 10.1016/j.bpj.2009.10.044.


Multi-level molecular clutches in motile cell processes.

Giannone G, Mège RM, Thoumine O.

Trends Cell Biol. 2009 Sep;19(9):475-86. doi: 10.1016/j.tcb.2009.07.001. Epub 2009 Aug 26. Review.


Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.

Coureuil M, Mikaty G, Miller F, Lécuyer H, Bernard C, Bourdoulous S, Duménil G, Mège RM, Weksler BB, Romero IA, Couraud PO, Nassif X.

Science. 2009 Jul 3;325(5936):83-7. doi: 10.1126/science.1173196. Epub 2009 Jun 11.


A molecular clutch between the actin flow and N-cadherin adhesions drives growth cone migration.

Bard L, Boscher C, Lambert M, Mège RM, Choquet D, Thoumine O.

J Neurosci. 2008 Jun 4;28(23):5879-90. doi: 10.1523/JNEUROSCI.5331-07.2008.


Cadherin-11 interacts with the FGF receptor and induces neurite outgrowth through associated downstream signalling.

Boscher C, Mège RM.

Cell Signal. 2008 Jun;20(6):1061-72. doi: 10.1016/j.cellsig.2008.01.008. Epub 2008 Jan 19.


Nucleation and growth of cadherin adhesions.

Lambert M, Thoumine O, Brevier J, Choquet D, Riveline D, Mège RM.

Exp Cell Res. 2007 Nov 15;313(19):4025-40. Epub 2007 Aug 8.


Regulation of cell-cell junctions by the cytoskeleton.

Mège RM, Gavard J, Lambert M.

Curr Opin Cell Biol. 2006 Oct;18(5):541-8. Epub 2006 Aug 14. Review.


Traction forces exerted through N-cadherin contacts.

Ganz A, Lambert M, Saez A, Silberzan P, Buguin A, Mège RM, Ladoux B.

Biol Cell. 2006 Dec;98(12):721-30.


A dileucine motif targets MCAM-l cell adhesion molecule to the basolateral membrane in MDCK cells.

Guezguez B, Vigneron P, Alais S, Jaffredo T, Gavard J, Mège RM, Dunon D.

FEBS Lett. 2006 Jun 26;580(15):3649-56. Epub 2006 Jun 2.


Regulation of N-cadherin dynamics at neuronal contacts by ligand binding and cytoskeletal coupling.

Thoumine O, Lambert M, Mège RM, Choquet D.

Mol Biol Cell. 2006 Feb;17(2):862-75. Epub 2005 Nov 30.


Once upon a time there was beta-catenin in cadherin-mediated signalling.

Gavard J, Mège RM.

Biol Cell. 2005 Dec;97(12):921-6.


[Regulation of cell adhesion by the cadherin cytoplasmic domain].

Gavard J, Marthiens V, Monnet C, Boscher C, Lambert M, Mège RM.

J Soc Biol. 2004;198(4):365-74. Review. French.


Tetanus neurotoxin-mediated cleavage of cellubrevin impairs epithelial cell migration and integrin-dependent cell adhesion.

Proux-Gillardeaux V, Gavard J, Irinopoulou T, Mège RM, Galli T.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6362-7. Epub 2005 Apr 25.


A novel function for cadherin-11 in the regulation of motor axon elongation and fasciculation.

Marthiens V, Gavard J, Padilla F, Monnet C, Castellani V, Lambert M, Mège RM.

Mol Cell Neurosci. 2005 Apr;28(4):715-26.


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