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Racial Differences and Factors Associated with Pregnancy in End Stage Kidney Disease Patients on Dialysis in the United States.

Shah S, Christianson AL, Meganathan K, Leonard AC, Schauer DP, Thakar CV.

J Am Soc Nephrol. 2019 Sep 25. pii: ASN.2019030234. doi: 10.1681/ASN.2019030234. [Epub ahead of print]


A Feasibility Study to Attribute Patients to Primary Interns on Inpatient Ward Teams Using Electronic Health Record Data.

Schumacher DJ, Wu DTY, Meganathan K, Li L, Kinnear B, Sall DR, Holmboe E, Carraccio C, van der Vleuten C, Busari J, Kelleher M, Schauer D, Warm E.

Acad Med. 2019 Sep;94(9):1376-1383. doi: 10.1097/ACM.0000000000002748.


Racial disparities and factors associated with pregnancy in kidney transplant recipients in the United States.

Shah S, Christianson AL, Verma P, Meganathan K, Leonard AC, Schauer DP, Thakar CV.

PLoS One. 2019 Aug 9;14(8):e0220916. doi: 10.1371/journal.pone.0220916. eCollection 2019.


A translational rheostat integrates euchromatin regulation and growth of pluripotent embryonic cells.

Meganathan K, Prakasam R, Kroll KL.

Stem Cell Investig. 2019 May 21;6:11. doi: 10.21037/sci.2019.05.01. eCollection 2019. No abstract available.


Nationwide salpingectomy rates for an indication of permanent contraception before and after published practice guidelines.

Polen-De C, Meganathan K, Lang P, Hohmann S, Jackson A, Whiteside JL.

Contraception. 2019 Aug;100(2):111-115. doi: 10.1016/j.contraception.2019.03.054. Epub 2019 Apr 30.


Temporal Trends in Incident Mortality in Dialysis Patients: Focus on Sex and Racial Disparities.

Shah S, Leonard AC, Meganathan K, Christianson AL, Thakar CV.

Am J Nephrol. 2019;49(3):241-253. doi: 10.1159/000497446. Epub 2019 Feb 28.


A Comparison of Existing Methods to Detect Weight Data Errors in a Pediatric Academic Medical Center.

Wu DTY, Meganathan K, Newcomb M, Ni Y, Dexheimer JW, Kirkendall ES, Spooner SA.

AMIA Annu Symp Proc. 2018 Dec 5;2018:1103-1109. eCollection 2018.


Pre-dialysis acute care hospitalizations and clinical outcomes in dialysis patients.

Shah S, Meganathan K, Christianson AL, Leonard AC, Thakar CV.

PLoS One. 2019 Jan 16;14(1):e0209578. doi: 10.1371/journal.pone.0209578. eCollection 2019.


Gender and Racial Disparities in Initial Hemodialysis Access and Outcomes in Incident End-Stage Renal Disease Patients.

Shah S, Leonard AC, Meganathan K, Christianson AL, Thakar CV.

Am J Nephrol. 2018;48(1):4-14. doi: 10.1159/000490624. Epub 2018 Jul 10.


Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development.

Meganathan K, Lewis EMA, Gontarz P, Liu S, Stanley EG, Elefanty AG, Huettner JE, Zhang B, Kroll KL.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11180-E11189. doi: 10.1073/pnas.1712365115. Epub 2017 Dec 11.


Nativity, Race-Ethnicity, and Dual Diagnosis among US Adults.

Szaflarski M, Bauldry S, Cubbins LA, Meganathan K.

Res Sociol Health Care. 2017;35:171-191.


Anxiety Disorders among US Immigrants: The Role of Immigrant Background and Social-Psychological Factors.

Szaflarski M, Cubbins LA, Meganathan K.

Issues Ment Health Nurs. 2017 Apr;38(4):317-326. doi: 10.1080/01612840.2017.1287790. Epub 2017 Mar 1.


Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue.

Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stöber R, Hammad S, Pütter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nüssler A, Thasler WE, Damm G, Seehofer D, Weiss TS, Dirsch O, Dahmen U, Gebhardt R, Chaudhari U, Meganathan K, Sachinidis A, Kelm J, Hofmann U, Zahedi RP, Guthke R, Blüthgen N, Dooley S, Hengstler JG.

Arch Toxicol. 2016 Oct;90(10):2513-29. doi: 10.1007/s00204-016-1761-4. Epub 2016 Jun 23.


Complexities of X chromosome inactivation status in female human induced pluripotent stem cells-a brief review and scientific update for autism research.

Dandulakis MG, Meganathan K, Kroll KL, Bonni A, Constantino JN.

J Neurodev Disord. 2016 Jun 9;8:22. doi: 10.1186/s11689-016-9155-8. eCollection 2016. Review.


Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests.

Shinde V, Hoelting L, Srinivasan SP, Meisig J, Meganathan K, Jagtap S, Grinberg M, Liebing J, Bluethgen N, Rahnenführer J, Rempel E, Stoeber R, Schildknecht S, Förster S, Godoy P, van Thriel C, Gaspar JA, Hescheler J, Waldmann T, Hengstler JG, Leist M, Sachinidis A.

Arch Toxicol. 2017 Feb;91(2):839-864. doi: 10.1007/s00204-016-1741-8. Epub 2016 May 17.


Differences in the Early Development of Human and Mouse Embryonic Stem Cells.

Gabdoulline R, Kaisers W, Gaspar A, Meganathan K, Doss MX, Jagtap S, Hescheler J, Sachinidis A, Schwender H.

PLoS One. 2015 Oct 16;10(10):e0140803. doi: 10.1371/journal.pone.0140803. eCollection 2015.


Major Depressive Disorder and Dysthymia at the Intersection of Nativity and Racial-Ethnic Origins.

Szaflarski M, Cubbins LA, Bauldry S, Meganathan K, Klepinger DH, Somoza E.

J Immigr Minor Health. 2016 Aug;18(4):749-63. doi: 10.1007/s10903-015-0293-y.


Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation.

Shinde V, Klima S, Sureshkumar PS, Meganathan K, Jagtap S, Rempel E, Rahnenführer J, Hengstler JG, Waldmann T, Hescheler J, Leist M, Sachinidis A.

J Vis Exp. 2015 Jun 17;(100):e52333. doi: 10.3791/52333.


Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells.

Meganathan K, Jagtap S, Srinivasan SP, Wagh V, Hescheler J, Hengstler J, Leist M, Sachinidis A.

Cell Death Dis. 2015 May 7;6:e1756. doi: 10.1038/cddis.2015.121.


Regulation of liver metabolism by the endosomal GTPase Rab5.

Zeigerer A, Bogorad RL, Sharma K, Gilleron J, Seifert S, Sales S, Berndt N, Bulik S, Marsico G, D'Souza RCJ, Lakshmanaperumal N, Meganathan K, Natarajan K, Sachinidis A, Dahl A, Holzhütter HG, Shevchenko A, Mann M, Koteliansky V, Zerial M.

Cell Rep. 2015 May 12;11(6):884-892. doi: 10.1016/j.celrep.2015.04.018. Epub 2015 Apr 30.


Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development.

Meganathan K, Sotiriadou I, Natarajan K, Hescheler J, Sachinidis A.

Int J Cardiol. 2015 Mar 15;183:117-28. doi: 10.1016/j.ijcard.2015.01.049. Epub 2015 Jan 27. Review.


A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system.

Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Zagoura D, Bremer S, Sachinidis A, Lazzari G.

Toxicol Lett. 2014 Nov 18;231(1):38-44. doi: 10.1016/j.toxlet.2014.08.023. Epub 2014 Sep 2.


Fam40b is required for lineage commitment of murine embryonic stem cells.

Wagh V, Doss MX, Sabour D, Niemann R, Meganathan K, Jagtap S, Gaspar JA, Ardestani MA, Papadopoulos S, Gajewski M, Winkler J, Hescheler J, Sachinidis A.

Cell Death Dis. 2014 Jul 10;5:e1320. doi: 10.1038/cddis.2014.273.


From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.

Balmer NV, Klima S, Rempel E, Ivanova VN, Kolde R, Weng MK, Meganathan K, Henry M, Sachinidis A, Berthold MR, Hengstler JG, Rahnenführer J, Waldmann T, Leist M.

Arch Toxicol. 2014 Jul;88(7):1451-68. doi: 10.1007/s00204-014-1279-6. Epub 2014 Jun 17.


Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain.

Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martínez Carrera L, Wirth R, Sachinidis A, Wirth B.

PLoS One. 2014 Feb 19;9(2):e89020. doi: 10.1371/journal.pone.0089020. eCollection 2014.


Human skin-derived precursor cells are poorly immunogenic and modulate the allogeneic immune response.

De Kock J, Meuleman P, Raicevic G, Rodrigues RM, Branson S, Meganathan K, De Boe V, Sachinidis A, Leroux-Roels G, Vanhaecke T, Lagneaux L, Rogiers V, Najar M.

Stem Cells. 2014 Aug;32(8):2215-28. doi: 10.1002/stem.1692.


Increasing use of computed tomographic perfusion and computed tomographic angiograms in acute ischemic stroke from 2006 to 2010.

Vagal A, Meganathan K, Kleindorfer DO, Adeoye O, Hornung R, Khatri P.

Stroke. 2014 Apr;45(4):1029-34. doi: 10.1161/STROKEAHA.113.004332. Epub 2014 Feb 25.


Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies.

Attia WA, Abd El Aziz OM, Spitkovsky D, Gaspar JA, Dröge P, Suhr F, Sabour D, Winkler J, Meganathan K, Jagtap S, Khalil M, Hescheler J, Konrad Brockmeier, Agapios Sachinidis, Kurt Pfannkuche.

Stem Cell Rev Rep. 2014 Feb;10(1):1-15.


Provider recognition and response to echocardiographic findings indicating pulmonary hypertension in the Veterans affairs medical center population.

Kingrey JF, Panos RJ, Ying J, Meganathan K, Vandivier R, Elwing JM.

Pulm Circ. 2013 Apr;3(2):389-95. doi: 10.4103/2045-8932.113184.


Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.

Rodrigues RM, De Kock J, Branson S, Vinken M, Meganathan K, Chaudhari U, Sachinidis A, Govaere O, Roskams T, De Boe V, Vanhaecke T, Rogiers V.

Stem Cells Dev. 2014 Jan 1;23(1):44-55. doi: 10.1089/scd.2013.0157. Epub 2013 Sep 21.


Faith-based HIV prevention and counseling programs: findings from the Cincinnati census of religious congregations.

Szaflarski M, Ritchey PN, Jacobson CJ, Williams RH, Baumann Grau A, Meganathan K, Ellison CG, Tsevat J.

AIDS Behav. 2013 Jun;17(5):1839-54. doi: 10.1007/s10461-013-0455-7.


All-trans retinoic acid and basic fibroblast growth factor synergistically direct pluripotent human embryonic stem cells to extraembryonic lineages.

Jagtap S, Meganathan K, Wagh V, Natarajan K, Hescheler J, Sachinidis A.

Stem Cell Res. 2013 Mar;10(2):228-40. doi: 10.1016/j.scr.2012.12.002. Epub 2012 Dec 9.


Current status of human pluripotent stem cell based in vitro toxicity tests.

Klaric M, Winkler J, Vojnits K, Meganathan K, Jagtap S, Ensenat-Waser R, Hescheler J, Sachinidis A, Bremer-Hoffmann S.

Front Biosci (Schol Ed). 2013 Jan 1;5:118-33. Review.


A tanscriptomics study to elucidate the toxicological mechanism of methylmercury chloride in a human stem cell based in vitro test.

Vojnits K, Ensenat-Waser R, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Bremer-Hoffmann S.

Curr Med Chem. 2012;19(36):6224-32.


Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.

Krug AK, Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, Kadereit S, Gerhard D, Sotiriadou I, Heke M, Natarajan K, Henry M, Winkler J, Marchan R, Stoppini L, Bosgra S, Westerhout J, Verwei M, Vilo J, Kortenkamp A, Hescheler J, Hothorn L, Bremer S, van Thriel C, Krause KH, Hengstler JG, Rahnenführer J, Leist M, Sachinidis A.

Arch Toxicol. 2013 Jan;87(1):123-43. doi: 10.1007/s00204-012-0967-3. Epub 2012 Nov 21.


Characterisation of a neural teratogenicity assay based on human ESCs differentiation following exposure to valproic acid.

Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Lazzari G.

Curr Med Chem. 2012;19(35):6065-71.


Identification of thalidomide-specific transcriptomics and proteomics signatures during differentiation of human embryonic stem cells.

Meganathan K, Jagtap S, Wagh V, Winkler J, Gaspar JA, Hildebrand D, Trusch M, Lehmann K, Hescheler J, Schlüter H, Sachinidis A.

PLoS One. 2012;7(8):e44228. doi: 10.1371/journal.pone.0044228. Epub 2012 Aug 28.


The development of academic geriatric medicine in the United States 2005 to 2010: an essential resource for improving the medical care of older adults.

Bragg EJ, Warshaw GA, Meganathan K, Brewer DE.

J Am Geriatr Soc. 2012 Aug;60(8):1540-5. doi: 10.1111/j.1532-5415.2012.04065.x. Epub 2012 Aug 2.


Postoperative heart block in children with common forms of congenital heart disease: results from the KID Database.

Anderson JB, Czosek RJ, Knilans TK, Meganathan K, Heaton P.

J Cardiovasc Electrophysiol. 2012 Dec;23(12):1349-54. doi: 10.1111/j.1540-8167.2012.02385.x. Epub 2012 Jun 26.


Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential.

De Kock J, Najar M, Bolleyn J, Al Battah F, Rodrigues RM, Buyl K, Raicevic G, Govaere O, Branson S, Meganathan K, Gaspar JA, Roskams T, Sachinidis A, Lagneaux L, Vanhaecke T, Rogiers V.

Stem Cells Dev. 2012 Dec 10;21(18):3309-23. doi: 10.1089/scd.2011.0723. Epub 2012 Jul 11.


Evaluation of developmental toxicants and signaling pathways in a functional test based on the migration of human neural crest cells.

Zimmer B, Lee G, Balmer NV, Meganathan K, Sachinidis A, Studer L, Leist M.

Environ Health Perspect. 2012 Aug;120(8):1116-22. doi: 10.1289/ehp.1104489. Epub 2012 May 9.


Pediatric syncope: National Hospital Ambulatory Medical Care Survey results.

Anderson JB, Czosek RJ, Cnota J, Meganathan K, Knilans TK, Heaton PC.

J Emerg Med. 2012 Oct;43(4):575-83. doi: 10.1016/j.jemermed.2012.01.020. Epub 2012 Mar 8.


Effect of chemopreventive agents on differentiation of mouse embryonic stem cells.

Wagh V, Jagtap S, Meganathan K, Potta SP, Winkler J, Hescheler J, Sachinidis A.

Front Biosci (Elite Ed). 2012 Jan 1;4:156-68.


Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure.

Colleoni S, Galli C, Gaspar JA, Meganathan K, Jagtap S, Hescheler J, Sachinidis A, Lazzari G.

Toxicol Sci. 2011 Dec;124(2):370-7. doi: 10.1093/toxsci/kfr245. Epub 2011 Sep 20.


Cardiac rhythm devices in the pediatric population: utilization and complications.

Czosek RJ, Meganathan K, Anderson JB, Knilans TK, Marino BS, Heaton PC.

Heart Rhythm. 2012 Feb;9(2):199-208. doi: 10.1016/j.hrthm.2011.09.004. Epub 2011 Sep 9.


Physician work intensity among medical specialties: emerging evidence on its magnitude and composition.

Horner RD, Szaflarski JP, Ying J, Meganathan K, Matthews G, Schroer B, Weber D, Raphaelson M.

Med Care. 2011 Nov;49(11):1007-11. doi: 10.1097/MLR.0b013e31822dcdc7.


Paul B. Beeson career development awards in aging research and U.S. medical schools aging and geriatric medicine programs.

Bragg EJ, Warshaw GA, van der Willik O, Meganathan K, Weber D, Cornwall D, Leonard AC.

J Am Geriatr Soc. 2011 Sep;59(9):1730-8. doi: 10.1111/j.1532-5415.2011.03546.x. Epub 2011 Aug 1.


Functional characterization and gene expression profiling of α-smooth muscle actin expressing cardiomyocytes derived from murine induced pluripotent stem cells.

Potta SP, Sheng X, Gaspar JA, Meganathan K, Jagtap S, Pfannkuche K, Winkler J, Hescheler J, Papadopoulos S, Sachinidis A.

Stem Cell Rev Rep. 2012 Mar;8(1):229-42. doi: 10.1007/s12015-011-9271-5. No abstract available.


False positive marks on unsuspicious screening mammography with computer-aided detection.

Mahoney MC, Meganathan K.

J Digit Imaging. 2011 Oct;24(5):772-7. doi: 10.1007/s10278-011-9389-7.

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