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Items: 10


Genetic Mechanisms Leading to Sex Differences Across Common Diseases and Anthropometric Traits.

Traglia M, Bseiso D, Gusev A, Adviento B, Park DS, Mefford JA, Zaitlen N, Weiss LA.

Genetics. 2017 Feb;205(2):979-992. doi: 10.1534/genetics.116.193623. Epub 2016 Dec 14.


Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.

Lee SA, Mefford JA, Huang Y, Witte JS, Martin JN, Haas DW, Mclaren PJ, Mushiroda T, Kubo M, Byakwaga H, Hunt PW, Kroetz DL.

AIDS. 2016 Jul 17;30(11):1807-15. doi: 10.1097/QAD.0000000000001124.


Mutational Landscape of Aggressive Prostate Tumors in African American Men.

Lindquist KJ, Paris PL, Hoffmann TJ, Cardin NJ, Kazma R, Mefford JA, Simko JP, Ngo V, Chen Y, Levin AM, Chitale D, Helfand BT, Catalona WJ, Rybicki BA, Witte JS.

Cancer Res. 2016 Apr 1;76(7):1860-8. doi: 10.1158/0008-5472.CAN-15-1787. Epub 2016 Feb 26.


Detecting gene-environment interactions in human birth defects: Study designs and statistical methods.

Tai CG, Graff RE, Liu J, Passarelli MN, Mefford JA, Shaw GM, Hoffmann TJ, Witte JS.

Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):692-702. doi: 10.1002/bdra.23382. Epub 2015 May 23.


Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.

Goswami S, Yee SW, Stocker S, Mosley JD, Kubo M, Castro R, Mefford JA, Wen C, Liang X, Witte J, Brett C, Maeda S, Simpson MD, Hedderson MM, Davis RL, Roden DM, Giacomini KM, Savic RM.

Clin Pharmacol Ther. 2014 Sep;96(3):370-9. doi: 10.1038/clpt.2014.109. Epub 2014 May 22. Erratum in: Clin Pharmacol Ther. 2014 Nov;96(5):626. Clin Pharmacol Ther. 2014 Nov;96(5):626.


Impact of polymorphisms in drug pathway genes on disease-free survival in adults with acute myeloid leukemia.

Yee SW, Mefford JA, Singh N, Percival ME, Stecula A, Yang K, Witte JS, Takahashi A, Kubo M, Matsuda K, Giacomini KM, Andreadis C.

J Hum Genet. 2013 Jun;58(6):353-61. doi: 10.1038/jhg.2013.38. Epub 2013 May 16.


Association of the innate immunity and inflammation pathway with advanced prostate cancer risk.

Kazma R, Mefford JA, Cheng I, Plummer SJ, Levin AM, Rybicki BA, Casey G, Witte JS.

PLoS One. 2012;7(12):e51680. doi: 10.1371/journal.pone.0051680. Epub 2012 Dec 14.


Joint association testing of common and rare genetic variants using hierarchical modeling.

Cardin NJ, Mefford JA, Witte JS.

Genet Epidemiol. 2012 Sep;36(6):642-51. doi: 10.1002/gepi.21659. Epub 2012 Jul 16.


A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.

Choi JH, Yee SW, Ramirez AH, Morrissey KM, Jang GH, Joski PJ, Mefford JA, Hesselson SE, Schlessinger A, Jenkins G, Castro RA, Johns SJ, Stryke D, Sali A, Ferrin TE, Witte JS, Kwok PY, Roden DM, Wilke RA, McCarty CA, Davis RL, Giacomini KM.

Clin Pharmacol Ther. 2011 Nov;90(5):674-84. doi: 10.1038/clpt.2011.165. Epub 2011 Sep 28.


Enumerating the gene sets in breast cancer, a "direct" alternative to hierarchical clustering.

Mefford D, Mefford JA.

BMC Genomics. 2010 Aug 23;11:482. doi: 10.1186/1471-2164-11-482.

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