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Items: 1 to 50 of 305

1.

Prospect and challenge of detecting dynamic gene copy number increases in stem cells by whole genome sequencing.

Fischer U, Backes C, Fehlmann T, Galata V, Keller A, Meese E.

J Mol Med (Berl). 2019 May 27. doi: 10.1007/s00109-019-01792-y. [Epub ahead of print]

PMID:
31134286
2.

Integrating Culture-based Antibiotic Resistance Profiles with Whole-genome Sequencing Data for 11,087 Clinical Isolates.

Galata V, Laczny CC, Backes C, Hemmrich-Stanisak G, Schmolke S, Franke A, Meese E, Herrmann M, von Müller L, Plum A, Müller R, Stähler C, Posch AE, Keller A.

Genomics Proteomics Bioinformatics. 2019 May 14. pii: S1672-0229(19)30092-0. doi: 10.1016/j.gpb.2018.11.002. [Epub ahead of print]

3.

Differential expression of miR-23a/b-3p and its target genes in male patients with subfertility.

Abu-Halima M, Ayesh BM, Hart M, Alles J, Fischer U, Hammadeh M, Keller A, Huleihel M, Meese E.

Fertil Steril. 2019 May 2. pii: S0015-0282(19)30306-1. doi: 10.1016/j.fertnstert.2019.03.025. [Epub ahead of print]

PMID:
31056312
4.

ClinOmicsTrailbc: a visual analytics tool for breast cancer treatment stratification.

Schneider L, Kehl T, Thedinga K, Grammes NL, Backes C, Mohr C, Schubert B, Lenhof K, Gerstner N, Daniel Hartkopf A, Wallwiener M, Kohlbacher O, Keller A, Meese E, Graf N, Lenhof HP.

Bioinformatics. 2019 Apr 30. pii: btz302. doi: 10.1093/bioinformatics/btz302. [Epub ahead of print]

PMID:
31038669
5.

Spring is in the air: seasonal profiles indicate vernal change of miRNA activity.

Ludwig N, Hecksteden A, Kahraman M, Fehlmann T, Laufer T, Kern F, Meyer T, Meese E, Keller A, Backes C.

RNA Biol. 2019 Aug;16(8):1034-1043. doi: 10.1080/15476286.2019.1612217. Epub 2019 May 10.

PMID:
31035857
6.

The sncRNA Zoo: a repository for circulating small noncoding RNAs in animals.

Fehlmann T, Backes C, Pirritano M, Laufer T, Galata V, Kern F, Kahraman M, Gasparoni G, Ludwig N, Lenhof HP, Gregersen HA, Francke R, Meese E, Simon M, Keller A.

Nucleic Acids Res. 2019 May 21;47(9):4431-4441. doi: 10.1093/nar/gkz227.

7.

An estimate of the total number of true human miRNAs.

Alles J, Fehlmann T, Fischer U, Backes C, Galata V, Minet M, Hart M, Abu-Halima M, Grässer FA, Lenhof HP, Keller A, Meese E.

Nucleic Acids Res. 2019 Apr 23;47(7):3353-3364. doi: 10.1093/nar/gkz097.

8.

Amplified Host Defense by Toll-Like Receptor-Mediated Downregulation of the Glucocorticoid-Induced Leucine Zipper (GILZ) in Macrophages.

Hoppstädter J, Diesel B, Linnenberger R, Hachenthal N, Flamini S, Minet M, Leidinger P, Backes C, Grässer F, Meese E, Bruscoli S, Riccardi C, Huwer H, Kiemer AK.

Front Immunol. 2019 Jan 22;9:3111. doi: 10.3389/fimmu.2018.03111. eCollection 2018.

9.

miR-34a: a new player in the regulation of T cell function by modulation of NF-κB signaling.

Hart M, Walch-Rückheim B, Friedmann KS, Rheinheimer S, Tänzer T, Glombitza B, Sester M, Lenhof HP, Hoth M, Schwarz EC, Keller A, Meese E.

Cell Death Dis. 2019 Jan 18;10(2):46. doi: 10.1038/s41419-018-1295-1.

10.

MicroRNA profiling from dried blood samples.

Diener C, Galata V, Keller A, Meese E.

Crit Rev Clin Lab Sci. 2019 Mar;56(2):111-117. doi: 10.1080/10408363.2018.1561641. Epub 2019 Jan 29.

PMID:
30696311
11.

MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo.

Henn D, Abu-Halima M, Wermke D, Falkner F, Thomas B, Köpple C, Ludwig N, Schulte M, Brockmann MA, Kim YJ, Sacks JM, Kneser U, Keller A, Meese E, Schmidt VJ.

J Transl Med. 2019 Jan 11;17(1):22. doi: 10.1186/s12967-019-1767-9.

12.

Acute Myeloid Leukemia Affects Mouse Sperm Parameters, Spontaneous Acrosome Reaction, and Fertility Capacity.

Michailov Y, Lunenfeld E, Kapilushnik J, Friedler S, Meese E, Huleihel M.

Int J Mol Sci. 2019 Jan 8;20(1). pii: E219. doi: 10.3390/ijms20010219.

13.

Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity.

Fehlmann T, Laufer T, Backes C, Kahramann M, Alles J, Fischer U, Minet M, Ludwig N, Kern F, Kehl T, Galata V, Düsterloh A, Schrörs H, Kohlhaas J, Bals R, Huwer H, Geffers L, Krüger R, Balling R, Lenhof HP, Meese E, Keller A.

RNA Biol. 2019 Jan;16(1):93-103. doi: 10.1080/15476286.2018.1559689. Epub 2018 Dec 26.

PMID:
30567465
14.

Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity.

Rounge TB, Umu SU, Keller A, Meese E, Ursin G, Tretli S, Lyle R, Langseth H.

Sci Rep. 2018 Dec 5;8(1):17650. doi: 10.1038/s41598-018-35974-4.

15.

Development of Spermatogenesis In Vitro in Three-Dimensional Culture from Spermatogonial Cells of Busulfan-Treated Immature Mice.

AbuMadighem A, Solomon R, Stepanovsky A, Kapelushnik J, Shi Q, Meese E, Lunenfeld E, Huleihel M.

Int J Mol Sci. 2018 Nov 29;19(12). pii: E3804. doi: 10.3390/ijms19123804.

16.

Epstein-Barr Virus Infection of Cell Lines Derived from Diffuse Large B-Cell Lymphomas Alters MicroRNA Loading of the Ago2 Complex.

Ayoubian H, Ludwig N, Fehlmann T, Menegatti J, Gröger L, Anastasiadou E, Trivedi P, Keller A, Meese E, Grässer FA.

J Virol. 2019 Jan 17;93(3). pii: e01297-18. doi: 10.1128/JVI.01297-18. Print 2019 Feb 1.

PMID:
30429351
17.

Genome-wide analysis of gene expression after one year of venom immunotherapy.

Karpinski P, Skiba P, Kosinska M, Rosiek-Biegus M, Królewicz E, Blin N, Meese E, Panaszek B, Nittner-Marszalska M, Sasiadek MM.

Immunol Lett. 2018 Dec;204:23-28. doi: 10.1016/j.imlet.2018.10.005. Epub 2018 Oct 10.

PMID:
30312636
18.

Modulation of intracellular calcium signaling by microRNA-34a-5p.

Diener C, Hart M, Alansary D, Poth V, Walch-Rückheim B, Menegatti J, Grässer F, Fehlmann T, Rheinheimer S, Niemeyer BA, Lenhof HP, Keller A, Meese E.

Cell Death Dis. 2018 Sep 27;9(10):1008. doi: 10.1038/s41419-018-1050-7.

19.

Next Generation Sequencing Analysis of Total Small Noncoding RNAs from Low Input RNA from Dried Blood Sampling.

Pirritano M, Fehlmann T, Laufer T, Ludwig N, Gasparoni G, Li Y, Meese E, Keller A, Simon M.

Anal Chem. 2018 Oct 16;90(20):11791-11796. doi: 10.1021/acs.analchem.8b03557. Epub 2018 Sep 25.

PMID:
30198258
20.

Limited Long-Term Impact of Insect Venom Immunotherapy on the Micro-RNA Landscape in Whole Blood.

Karpinski P, Kahraman M, Ludwig N, Skiba P, Kosinska M, Rosiek-Biegus M, Królewicz E, Panaszek B, Nittner-Marszalska M, Blin N, Keller A, Meese E, Sasiadek MM.

J Investig Allergol Clin Immunol. 2019;29(3):206-212. doi: 10.18176/jiaci.0303. Epub 2018 Sep 5.

PMID:
30183661
21.

The role of TCF3 as potential master regulator in blastemal Wilms tumors.

Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP.

Int J Cancer. 2019 Mar 15;144(6):1432-1443. doi: 10.1002/ijc.31834. Epub 2018 Nov 13.

PMID:
30155889
22.

MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer.

Kahraman M, Röske A, Laufer T, Fehlmann T, Backes C, Kern F, Kohlhaas J, Schrörs H, Saiz A, Zabler C, Ludwig N, Fasching PA, Strick R, Rübner M, Beckmann MW, Meese E, Keller A, Schrauder MG.

Sci Rep. 2018 Aug 2;8(1):11584. doi: 10.1038/s41598-018-29917-2.

23.

Transcriptional profiling of HERV-K(HML-2) in amyotrophic lateral sclerosis and potential implications for expression of HML-2 proteins.

Mayer J, Harz C, Sanchez L, Pereira GC, Maldener E, Heras SR, Ostrow LW, Ravits J, Batra R, Meese E, García-Pérez JL, Goodier JL.

Mol Neurodegener. 2018 Aug 2;13(1):39. doi: 10.1186/s13024-018-0275-3.

24.

Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.

Keller A, Fehlmann T, Ludwig N, Kahraman M, Laufer T, Backes C, Vogelmeier C, Diener C, Biertz F, Herr C, Jörres RA, Lenhof HP, Meese E, Bals R; COSYCONET Study Group.

Genomics Proteomics Bioinformatics. 2018 Jun;16(3):162-171. doi: 10.1016/j.gpb.2018.06.001. Epub 2018 Jul 5.

25.

Micro-RNA-Regulated Proangiogenic Signaling in Arteriovenous Loops in Patients with Combined Vascular and Soft-Tissue Reconstructions: Revisiting the Nutrient Flap Concept.

Henn D, Abu-Halima M, Falkner F, Wermke D, Meme LG, Kühner C, Keller A, Kneser U, Meese E, Schmidt VJ.

Plast Reconstr Surg. 2018 Oct;142(4):489e-502e. doi: 10.1097/PRS.0000000000004750.

PMID:
29979372
26.

The deterministic role of 5-mers in microRNA-gene targeting.

Hart M, Kern F, Backes C, Rheinheimer S, Fehlmann T, Keller A, Meese E.

RNA Biol. 2018;15(6):819-825. doi: 10.1080/15476286.2018.1462652. Epub 2018 May 11.

27.

REGGAE: a novel approach for the identification of key transcriptional regulators.

Kehl T, Schneider L, Kattler K, Stöckel D, Wegert J, Gerstner N, Ludwig N, Distler U, Schick M, Keller U, Tenzer S, Gessler M, Walter J, Keller A, Graf N, Meese E, Lenhof HP.

Bioinformatics. 2018 Oct 15;34(20):3503-3510. doi: 10.1093/bioinformatics/bty372.

28.

Small ncRNA-Seq Results of Human Tissues: Variations Depending on Sample Integrity.

Ludwig N, Fehlmann T, Galata V, Franke A, Backes C, Meese E, Keller A.

Clin Chem. 2018 Jul;64(7):1074-1084. doi: 10.1373/clinchem.2017.285767. Epub 2018 Apr 24.

PMID:
29691221
29.

Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome.

Abu-Halima M, Kahraman M, Henn D, Rädle-Hurst T, Keller A, Abdul-Khaliq H, Meese E.

J Transl Med. 2018 Mar 12;16(1):60. doi: 10.1186/s12967-018-1429-3.

30.

Gene amplification in mesenchymal stem cells and during differentiation towards adipocytes or osteoblasts.

Altmayer NC, Galata V, Warschburger N, Keller A, Meese E, Fischer U.

Oncotarget. 2017 Dec 1;9(2):1803-1812. doi: 10.18632/oncotarget.22804. eCollection 2018 Jan 5.

31.

About miRNAs, miRNA seeds, target genes and target pathways.

Kehl T, Backes C, Kern F, Fehlmann T, Ludwig N, Meese E, Lenhof HP, Keller A.

Oncotarget. 2017 Nov 9;8(63):107167-107175. doi: 10.18632/oncotarget.22363. eCollection 2017 Dec 5.

32.

A high-resolution map of the human small non-coding transcriptome.

Fehlmann T, Backes C, Alles J, Fischer U, Hart M, Kern F, Langseth H, Rounge T, Umu SU, Kahraman M, Laufer T, Haas J, Staehler C, Ludwig N, Hübenthal M, Meder B, Franke A, Lenhof HP, Meese E, Keller A.

Bioinformatics. 2018 May 15;34(10):1621-1628. doi: 10.1093/bioinformatics/btx814.

PMID:
29281000
33.

A comprehensive profile of circulating RNAs in human serum.

Umu SU, Langseth H, Bucher-Johannessen C, Fromm B, Keller A, Meese E, Lauritzen M, Leithaug M, Lyle R, Rounge TB.

RNA Biol. 2018 Feb 1;15(2):242-250. doi: 10.1080/15476286.2017.1403003. Epub 2017 Dec 8.

34.

Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization.

Abu-Halima M, Häusler S, Backes C, Fehlmann T, Staib C, Nestel S, Nazarenko I, Meese E, Keller A.

Sci Rep. 2017 Oct 19;7(1):13525. doi: 10.1038/s41598-017-13683-8.

35.

miRCarta: a central repository for collecting miRNA candidates.

Backes C, Fehlmann T, Kern F, Kehl T, Lenhof HP, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D160-D167. doi: 10.1093/nar/gkx851.

36.

IMOTA: an interactive multi-omics tissue atlas for the analysis of human miRNA-target interactions.

Palmieri V, Backes C, Ludwig N, Fehlmann T, Kern F, Meese E, Keller A.

Nucleic Acids Res. 2018 Jan 4;46(D1):D770-D775. doi: 10.1093/nar/gkx701.

37.

Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway.

Freis A, Keller A, Ludwig N, Meese E, Jauckus J, Rehnitz J, Capp E, Strowitzki T, Germeyer A.

Reproduction. 2017 Dec;154(6):799-805. doi: 10.1530/REP-17-0396. Epub 2017 Sep 29.

PMID:
28971890
38.

MiR-148a impairs Ras/ERK signaling in B lymphocytes by targeting SOS proteins.

Alles J, Ludwig N, Rheinheimer S, Leidinger P, Grässer FA, Keller A, Meese E.

Oncotarget. 2017 May 7;8(34):56417-56427. doi: 10.18632/oncotarget.17662. eCollection 2017 Aug 22.

39.

Web-based NGS data analysis using miRMaster: a large-scale meta-analysis of human miRNAs.

Fehlmann T, Backes C, Kahraman M, Haas J, Ludwig N, Posch AE, Würstle ML, Hübenthal M, Franke A, Meder B, Meese E, Keller A.

Nucleic Acids Res. 2017 Sep 6;45(15):8731-8744. doi: 10.1093/nar/gkx595.

40.

Sources to variability in circulating human miRNA signatures.

Keller A, Rounge T, Backes C, Ludwig N, Gislefoss R, Leidinger P, Langseth H, Meese E.

RNA Biol. 2017 Dec 2;14(12):1791-1798. doi: 10.1080/15476286.2017.1367888. Epub 2017 Sep 13.

41.

Bias in recent miRBase annotations potentially associated with RNA quality issues.

Ludwig N, Becker M, Schumann T, Speer T, Fehlmann T, Keller A, Meese E.

Sci Rep. 2017 Jul 12;7(1):5162. doi: 10.1038/s41598-017-05070-0.

42.

Analysis of circulating microRNAs in patients with repaired Tetralogy of Fallot with and without heart failure.

Abu-Halima M, Meese E, Keller A, Abdul-Khaliq H, Rädle-Hurst T.

J Transl Med. 2017 Jul 10;15(1):156. doi: 10.1186/s12967-017-1255-z.

43.

Technical Stability and Biological Variability in MicroRNAs from Dried Blood Spots: A Lung Cancer Therapy-Monitoring Showcase.

Kahraman M, Laufer T, Backes C, Schrörs H, Fehlmann T, Ludwig N, Kohlhaas J, Meese E, Wehler T, Bals R, Keller A.

Clin Chem. 2017 Sep;63(9):1476-1488. doi: 10.1373/clinchem.2017.271619. Epub 2017 Jul 5.

44.

Characterization of micro-RNA Profile in the Blood of Patients with Marfan's Syndrome.

Abu-Halima M, Ludwig N, Rädle-Hurst T, Keller A, Motsch L, Marsollek I, El Rahman MA, Abdul-Khaliq H, Meese E.

Thorac Cardiovasc Surg. 2018 Jan;66(1):116-124. doi: 10.1055/s-0037-1604083. Epub 2017 Jul 5.

PMID:
28679133
45.

TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo.

Belkacemi T, Niermann A, Hofmann L, Wissenbach U, Birnbaumer L, Leidinger P, Backes C, Meese E, Keller A, Bai X, Scheller A, Kirchhoff F, Philipp SE, Weissgerber P, Flockerzi V, Beck A.

Glia. 2017 Sep;65(9):1535-1549. doi: 10.1002/glia.23180. Epub 2017 Jun 21.

46.

Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases.

Abu-Halima M, Poryo M, Ludwig N, Mark J, Marsollek I, Giebels C, Petersen J, Schäfers HJ, Grundmann U, Pickardt T, Keller A, Meese E, Abdul-Khaliq H.

J Transl Med. 2017 May 30;15(1):117. doi: 10.1186/s12967-017-1213-9.

47.

RegulatorTrail: a web service for the identification of key transcriptional regulators.

Kehl T, Schneider L, Schmidt F, Stöckel D, Gerstner N, Backes C, Meese E, Keller A, Schulz MH, Lenhof HP.

Nucleic Acids Res. 2017 Jul 3;45(W1):W146-W153. doi: 10.1093/nar/gkx350.

48.

Specific amplifications and copy number decreases during human neural stem cells differentiation towards astrocytes, neurons and oligodendrocytes.

Fischer U, Kim E, Keller A, Meese E.

Oncotarget. 2017 Apr 18;8(16):25872-25884. doi: 10.18632/oncotarget.15980.

49.

MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2.

Werner TV, Hart M, Nickels R, Kim YJ, Menger MD, Bohle RM, Keller A, Ludwig N, Meese E.

Aging (Albany NY). 2017 Mar 23;9(3):932-954. doi: 10.18632/aging.101201.

50.

Exploring ncRNAs in Alzheimer's disease by miRMaster.

Fehlmann T, Meese E, Keller A.

Oncotarget. 2017 Jan 17;8(3):3771-3772. doi: 10.18632/oncotarget.14054. No abstract available.

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