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Items: 11


Enhanced Precision of Circular Dichroism Spectral Measurements Permits Detection of Subtle Higher Order Structural Changes in Therapeutic Proteins.

Barnett GV, Balakrishnan G, Chennamsetty N, Meengs B, Meyer J, Bongers J, Ludwig R, Tao L, Das TK, Leone A, Kar SR.

J Pharm Sci. 2018 Oct;107(10):2559-2569. doi: 10.1016/j.xphs.2018.06.007. Epub 2018 Jun 18.


Interleukin (IL) 31 induces in cynomolgus monkeys a rapid and intense itch response that can be inhibited by an IL-31 neutralizing antibody.

Lewis KE, Holdren MS, Maurer MF, Underwood S, Meengs B, Julien SH, Byrnes-Blake KA, Freeman JA, Bukowski TR, Wolf AC, Hamacher NB, Rixon MW, Dillon SR.

J Eur Acad Dermatol Venereol. 2017 Jan;31(1):142-150. doi: 10.1111/jdv.13794. Epub 2016 Aug 8.


Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies.

Maurer MF, Garrigues U, Jaspers SR, Meengs B, Rixon MW, Stevens BL, Lewis KB, Julien SH, Bukowski TR, Wolf AC, Hamacher NB, Snavely M, Dillon SR.

MAbs. 2012 Jan-Feb;4(1):69-83. doi: 10.4161/mabs.4.1.18713.


Generation of a high-affinity Fcgamma receptor by Ig-domain swapping between human CD64A and CD16A.

Ellsworth JL, Hamacher N, Harder B, Maurer M, Bukowski TR, Lantry M, Noriega C, Rixon MW, Fox B, Lewis K, Meengs B, Rollins E, Greeff K, Meyer J, Birks C.

Protein Eng Des Sel. 2010 Apr;23(4):299-309. doi: 10.1093/protein/gzq007. Epub 2010 Feb 11.


A dual-targeting PDGFRbeta/VEGF-A molecule assembled from stable antibody fragments demonstrates anti-angiogenic activity in vitro and in vivo.

Mabry R, Gilbertson DG, Frank A, Vu T, Ardourel D, Ostrander C, Stevens B, Julien S, Franke S, Meengs B, Brody J, Presnell S, Hamacher NB, Lantry M, Wolf A, Bukowski T, Rosler R, Yen C, Anderson-Haley M, Brasel K, Pan Q, Franklin H, Thompson P, Dodds M, Underwood S, Peterson S, Sivakumar PV, Snavely M.

MAbs. 2010 Jan-Feb;2(1):20-34. Epub 2010 Jan 2.


Engineering of stable bispecific antibodies targeting IL-17A and IL-23.

Mabry R, Lewis KE, Moore M, McKernan PA, Bukowski TR, Bontadelli K, Brender T, Okada S, Lum K, West J, Kuijper JL, Ardourel D, Franke S, Lockwood L, Vu T, Frank A, Appleby MW, Wolf A, Reardon B, Hamacher NB, Stevens B, Lewis P, Lewis KB, Gilbertson DG, Lantry M, Julien SH, Ostrander C, Chan C, Byrnes-Blake K, Brody J, Presnell S, Meengs B, Levin SD, Snavely M.

Protein Eng Des Sel. 2010 Mar;23(3):115-27. doi: 10.1093/protein/gzp073. Epub 2009 Dec 18.


Comparison of the ability of wild type and stabilized human IgG(4) to undergo Fab arm exchange with endogenous IgG(4)in vitro and in vivo.

Lewis KB, Meengs B, Bondensgaard K, Chin L, Hughes SD, Kjaer B, Lund S, Wang L.

Mol Immunol. 2009 Oct;46(16):3488-94. doi: 10.1016/j.molimm.2009.07.009. Epub 2009 Aug 14.


Bioavailability and relative tissue distribution of [125I]-recombinant human thrombin following intravenous or subcutaneous administration to non-human primates.

Visich JE, Byrnes-Blake KA, Lewis KB, Meengs B, Rogge MC.

J Thromb Haemost. 2006 Sep;4(9):1962-8. Epub 2006 Jun 22.


Lisofylline causes rapid and prolonged suppression of serum levels of free fatty acids.

Bursten SL, Federighi D, Wald J, Meengs B, Spickler W, Nudelman E.

J Pharmacol Exp Ther. 1998 Jan;284(1):337-45.


Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells.

West J, Tompkins CK, Balantac N, Nudelman E, Meengs B, White T, Bursten S, Coleman J, Kumar A, Singer JW, Leung DW.

DNA Cell Biol. 1997 Jun;16(6):691-701.


Isolation and expression of an isoform of human CDP-diacylglycerol synthase cDNA.

Weeks R, Dowhan W, Shen H, Balantac N, Meengs B, Nudelman E, Leung DW.

DNA Cell Biol. 1997 Mar;16(3):281-9.


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