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Items: 1 to 50 of 57

1.

Resistance to HIV protease inhibitors: a comparison of enzyme inhibition and antiviral potency.

Klabe RM, Bacheler LT, Ala PJ, Erickson-Viitanen S, Meek JL.

Biochemistry. 1998 Jun 16;37(24):8735-42.

PMID:
9628735
2.

Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies.

Jadhav PK, Woerner FJ, Lam PY, Hodge CN, Eyermann CJ, Man HW, Daneker WF, Bacheler LT, Rayner MM, Meek JL, Erickson-Viitanen S, Jackson DA, Calabrese JC, Schadt M, Chang CH.

J Med Chem. 1998 Apr 23;41(9):1446-55.

PMID:
9554878
3.

Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450.

Hodge CN, Aldrich PE, Bacheler LT, Chang CH, Eyermann CJ, Garber S, Grubb M, Jackson DA, Jadhav PK, Korant B, Lam PY, Maurin MB, Meek JL, Otto MJ, Rayner MM, Reid C, Sharpe TR, Shum L, Winslow DL, Erickson-Viitanen S.

Chem Biol. 1996 Apr;3(4):301-14.

4.

Potency and selectivity of inhibition of human immunodeficiency virus protease by a small nonpeptide cyclic urea, DMP 323.

Erickson-Viitanen S, Klabe RM, Cawood PG, O'Neal PL, Meek JL.

Antimicrob Agents Chemother. 1994 Jul;38(7):1628-34.

5.

Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors.

Lam PY, Jadhav PK, Eyermann CJ, Hodge CN, Ru Y, Bacheler LT, Meek JL, Otto MJ, Rayner MM, Wong YN, et al.

Science. 1994 Jan 21;263(5145):380-4.

PMID:
8278812
6.

Rapid purification of inositol monophosphate phosphatase from beef brain.

Meek JL, Rice TJ, Anton E.

Biochem Biophys Res Commun. 1988 Oct 14;156(1):143-8.

PMID:
2845970
7.

Demonstration of inositol 1,3,4,5-tetrakisphosphate receptor binding.

Theibert AB, Supattapone S, Worley PF, Baraban JM, Meek JL, Snyder SH.

Biochem Biophys Res Commun. 1987 Nov 13;148(3):1283-9.

PMID:
2825681
8.

Inositol bis-, tris-, and tetrakis(phosphate)s: analysis in tissues by HPLC.

Meek JL.

Proc Natl Acad Sci U S A. 1986 Jun;83(12):4162-6.

9.

Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus.

Nicoletti F, Meek JL, Iadarola MJ, Chuang DM, Roth BL, Costa E.

J Neurochem. 1986 Jan;46(1):40-6.

PMID:
2866236
10.

Estradiol benzoate decreases nigral GABAergic activity in male rats.

Nicoletti F, Meek JL.

Brain Res. 1985 Apr 15;332(1):179-83.

PMID:
2986760
11.
13.
14.
15.
16.

Acetylcholine measurement by high-performance liquid chromatography using an enzyme-loaded postcolumn reactor.

Eva C, Hadjiconstantinou M, Neff NH, Meek JL.

Anal Biochem. 1984 Dec;143(2):320-4.

PMID:
6397998
17.

Enkephalin biosynthesis in adrenal medulla. Modulation of proenkephalin mRNA content of cultured chromaffin cells by 8-bromo-adenosine 3',5'-monophosphate.

Quach TT, Tang F, Kageyama H, Mocchetti I, Guidotti A, Meek JL, Costa E, Schwartz JP.

Mol Pharmacol. 1984 Sep;26(2):255-60.

PMID:
6548292
18.

Measurement of acetylcholine turnover rate in brain: an adjunct to a simple HPLC method for choline and acetylcholine.

Potter PE, Hadjiconstantinou M, Meek JL, Neff NH.

J Neurochem. 1984 Jul;43(1):288-90.

PMID:
6726255
19.
20.

Cholecystokinin turnover in brain.

Meek JL, Iadarola MJ, Giorgi O.

Brain Res. 1983 Oct 16;276(2):375-8.

PMID:
6313133
21.

Acetylcholine and choline in neuronal tissue measured by HPLC with electrochemical detection.

Potter PE, Meek JL, Neff NH.

J Neurochem. 1983 Jul;41(1):188-94.

PMID:
6864218
22.
23.

Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin).

Guidotti A, Konkel DR, Ebstein B, Corda MG, Wise BC, Krutzsch H, Meek JL, Costa E.

Proc Natl Acad Sci U S A. 1982 Oct;79(19):6084-8.

24.

Specific high-affinity binding of L-[3H]aspartate to rat brain membranes.

Di Lauro A, Meek JL, Costa E.

J Neurochem. 1982 May;38(5):1261-7.

PMID:
7062051
25.
26.

Is aspartic acid the neurotransmitter of the perforant pathway?

Di Lauro A, Schmid RW, Meek JL.

Brain Res. 1981 Mar 2;207(2):476-80.

PMID:
6258744
27.

Evidence for a tonic GABAergic control of serotonin neurons in the median raphe nucleus.

Forchetti CM, Meek JL.

Brain Res. 1981 Feb 9;206(1):208-12.

PMID:
7470888
29.

Separation of neuropeptides by HPLC.

Meek JL.

Adv Biochem Psychopharmacol. 1980;22:145-51. No abstract available.

PMID:
7395595
30.

The effects of antidepressants on serotonin turnover in discrete regions of rat brain.

Marco EJ, Meek JL.

Naunyn Schmiedebergs Arch Pharmacol. 1979 Jan;306(1):75-9.

PMID:
311440
31.

Studies of serotonin neurotoxins in discrete brain nuclei.

Meek JL.

Ann N Y Acad Sci. 1978 Jun 12;305:190-7. No abstract available.

PMID:
152080
33.

Use of high pressure liquid chromatography (HPLC) to study enkephalins.

Meek JL, Bohan TP.

Adv Biochem Psychopharmacol. 1978;18:141-7. No abstract available.

PMID:
645456
34.

Modulation of brain tryptophan hydroxylase activity by brain tryptophan content.

Neckers LM, Biggio G, Moja E, Meek JL.

J Pharmacol Exp Ther. 1977 Apr;201(1):110-6.

PMID:
850134
35.

Enkephalin catabolism in vitro and in vivo.

Meek JL, Yang HY, Costa E.

Neuropharmacology. 1977 Feb;16(2):151-4. No abstract available.

PMID:
402592
36.

Measurement of 5HT turnover rate in discrete nuclei of rat brain.

Neckers LM, Meek JL.

Life Sci. 1976 Nov 15;19(10):1579-84. No abstract available.

PMID:
994702
37.

Tryptophan hydroxylase in discrete brain nuclei: comparison of activity in vitro and in vivo.

Meek JL, Lofstrandh S.

Eur J Pharmacol. 1976 Jun;37(2):377-80.

PMID:
1085253
38.

Reduction of tryptophan hydroxylase activity and 5-hydroxytryptamine concentration in certain rat brain nuclei after p-chloroamphetamine.

Neckers LM, Bertilsson L, Koslow SH, Meek JL.

J Pharmacol Exp Ther. 1976 Feb;196(2):333-8.

PMID:
1255480
40.
41.

Measurement of tryptophan hydroxylase in single brain nuclei by high pressure liquid chromatography.

Meek JL, Neckers LM.

Brain Res. 1975 Jun 27;91(2):336-40. No abstract available.

PMID:
1164684
42.

Occurrence and localization of brain phenolsulphotransferase.

Foldes A, Meek JL.

J Neurochem. 1974 Aug;23(2):303-7. No abstract available.

PMID:
4214341
43.

Experimental pathogenicity of recent North American isolates of Yersinia enterocolitica.

Quan TJ, Meek JL, Tsuchiya KR, Hudson BW, Barnes AM.

J Infect Dis. 1974 Mar;129(3):341-4. No abstract available.

PMID:
4816308
44.

Hallucinogenic phenylethylamines: interactions with serotonin turnover and receptors.

Andén NE, Corrodi H, Fuxe K, Meek JL.

Eur J Pharmacol. 1974 Feb;25(2):176-84. No abstract available.

PMID:
4435021
45.

Rat brain phenolsulfotransferase: partial purification and some properties.

Foldes A, Meek JL.

Biochim Biophys Acta. 1973 Dec 19;327(2):365-74. No abstract available.

PMID:
4778939
46.

Is cerebrospinal fluid the major avenue for the removal of 5-hydroxyindoleacetic acid from the brain?

Meek JL, Neff NH.

Neuropharmacology. 1973 May;12(5):497-9. No abstract available.

PMID:
4708479
47.
48.

Monoamine oxidase activity of rat spinal cord after transection.

Goridis C, Meek JL, Neff NH.

Life Sci I. 1972 Sep 15;11(18):861-6. No abstract available.

PMID:
4511739
49.
50.

Acidic and neutral metabolites of norepinephrine: their metabolism and transport from brain.

Meek JL, Neff NH.

J Pharmacol Exp Ther. 1972 Jun;181(3):457-62. No abstract available.

PMID:
5033012

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