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Items: 28

1.

Global chemical effects of the microbiome include new bile-acid conjugations.

Quinn RA, Melnik AV, Vrbanac A, Fu T, Patras KA, Christy MP, Bodai Z, Belda-Ferre P, Tripathi A, Chung LK, Downes M, Welch RD, Quinn M, Humphrey G, Panitchpakdi M, Weldon KC, Aksenov A, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa EA, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz JM, Meehan MJ, Gentry E, Arthur TD, Komor AC, Poulsen O, Boland BS, Chang JT, Sandborn WJ, Lim M, Garg N, Lumeng JC, Xavier RJ, Kazmierczak BI, Jain R, Egan M, Rhee KE, Ferguson D, Raffatellu M, Vlamakis H, Haddad GG, Siegel D, Huttenhower C, Mazmanian SK, Evans RM, Nizet V, Knight R, Dorrestein PC.

Nature. 2020 Mar;579(7797):123-129. doi: 10.1038/s41586-020-2047-9. Epub 2020 Feb 26.

PMID:
32103176
2.

Intermittent Hypoxia and Hypercapnia Reproducibly Change the Gut Microbiome and Metabolome across Rodent Model Systems.

Tripathi A, Xu ZZ, Xue J, Poulsen O, Gonzalez A, Humphrey G, Meehan MJ, Melnik AV, Ackermann G, Zhou D, Malhotra A, Haddad GG, Dorrestein PC, Knight R.

mSystems. 2019 Apr 30;4(2). pii: e00058-19. doi: 10.1128/mSystems.00058-19. eCollection 2019 Mar-Apr.

3.

Intermittent Hypoxia and Hypercapnia, a Hallmark of Obstructive Sleep Apnea, Alters the Gut Microbiome and Metabolome.

Tripathi A, Melnik AV, Xue J, Poulsen O, Meehan MJ, Humphrey G, Jiang L, Ackermann G, McDonald D, Zhou D, Knight R, Dorrestein PC, Haddad GG.

mSystems. 2018 Jun 5;3(3). pii: e00020-18. doi: 10.1128/mSystems.00020-18. eCollection 2018 May-Jun.

4.

Top-Down Atmospheric Ionization Mass Spectrometry Microscopy Combined With Proteogenomics.

Hsu CC, Baker MW, Gaasterland T, Meehan MJ, Macagno ER, Dorrestein PC.

Anal Chem. 2017 Aug 15;89(16):8251-8258. doi: 10.1021/acs.analchem.7b01096. Epub 2017 Jul 24.

5.

Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats.

Petras D, Nothias LF, Quinn RA, Alexandrov T, Bandeira N, Bouslimani A, Castro-Falcón G, Chen L, Dang T, Floros DJ, Hook V, Garg N, Hoffner N, Jiang Y, Kapono CA, Koester I, Knight R, Leber CA, Ling TJ, Luzzatto-Knaan T, McCall LI, McGrath AP, Meehan MJ, Merritt JK, Mills RH, Morton J, Podvin S, Protsyuk I, Purdy T, Satterfield K, Searles S, Shah S, Shires S, Steffen D, White M, Todoric J, Tuttle R, Wojnicz A, Sapp V, Vargas F, Yang J, Zhang C, Dorrestein PC.

Anal Chem. 2016 Nov 15;88(22):10775-10784. Epub 2016 Oct 24.

6.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

7.

Biochemical Establishment and Characterization of EncM's Flavin-N5-oxide Cofactor.

Teufel R, Stull F, Meehan MJ, Michaudel Q, Dorrestein PC, Palfey B, Moore BS.

J Am Chem Soc. 2015 Jul 1;137(25):8078-85. doi: 10.1021/jacs.5b03983. Epub 2015 Jun 19.

8.

Phenotyping drug polypharmacology via eicosanoid profiling of blood.

Song J, Liu X, Rao TS, Chang L, Meehan MJ, Blevitt JM, Wu J, Dorrestein PC, Milla ME.

J Lipid Res. 2015 Aug;56(8):1492-500. doi: 10.1194/jlr.M058677. Epub 2015 May 28.

9.

Molecular cartography of the human skin surface in 3D.

Bouslimani A, Porto C, Rath CM, Wang M, Guo Y, Gonzalez A, Berg-Lyon D, Ackermann G, Moeller Christensen GJ, Nakatsuji T, Zhang L, Borkowski AW, Meehan MJ, Dorrestein K, Gallo RL, Bandeira N, Knight R, Alexandrov T, Dorrestein PC.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2120-9. doi: 10.1073/pnas.1424409112. Epub 2015 Mar 30.

10.

Direct detection of fungal siderophores on bats with white-nose syndrome via fluorescence microscopy-guided ambient ionization mass spectrometry.

Mascuch SJ, Moree WJ, Hsu CC, Turner GG, Cheng TL, Blehert DS, Kilpatrick AM, Frick WF, Meehan MJ, Dorrestein PC, Gerwick L.

PLoS One. 2015 Mar 17;10(3):e0119668. doi: 10.1371/journal.pone.0119668. eCollection 2015.

11.

Mechanism of action of thalassospiramides, a new class of calpain inhibitors.

Lu L, Meehan MJ, Gu S, Chen Z, Zhang W, Zhang G, Liu L, Huang X, Dorrestein PC, Xu Y, Moore BS, Qian PY.

Sci Rep. 2015 Mar 5;5:8783. doi: 10.1038/srep08783.

12.

A highly efficient, high-throughput lipidomics platform for the quantitative detection of eicosanoids in human whole blood.

Song J, Liu X, Wu J, Meehan MJ, Blevitt JM, Dorrestein PC, Milla ME.

Anal Biochem. 2013 Feb 15;433(2):181-8. doi: 10.1016/j.ab.2012.10.022. Epub 2012 Oct 26.

PMID:
23103340
13.

Analysis of the ketosynthase-chain length factor heterodimer from the fredericamycin polyketide synthase.

Szu PH, Govindarajan S, Meehan MJ, Das A, Nguyen DD, Dorrestein PC, Minshull J, Khosla C.

Chem Biol. 2011 Aug 26;18(8):1021-31. doi: 10.1016/j.chembiol.2011.07.015.

14.

Connecting chemotypes and phenotypes of cultured marine microbial assemblages by imaging mass spectrometry.

Yang YL, Xu Y, Kersten RD, Liu WT, Meehan MJ, Moore BS, Bandeira N, Dorrestein PC.

Angew Chem Int Ed Engl. 2011 Jun 20;50(26):5839-42. doi: 10.1002/anie.201101225. Epub 2011 May 13. No abstract available.

15.

FT-ICR-MS characterization of intermediates in the biosynthesis of the α-methylbutyrate side chain of lovastatin by the 277 kDa polyketide synthase LovF.

Meehan MJ, Xie X, Zhao X, Xu W, Tang Y, Dorrestein PC.

Biochemistry. 2011 Jan 18;50(2):287-99. Epub 2010 Dec 22.

16.

Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis.

Zhou H, Qiao K, Gao Z, Meehan MJ, Li JW, Zhao X, Dorrestein PC, Vederas JC, Tang Y.

J Am Chem Soc. 2010 Apr 7;132(13):4530-1. doi: 10.1021/ja100060k.

17.

Acyltransferase mediated polyketide release from a fungal megasynthase.

Xie X, Meehan MJ, Xu W, Dorrestein PC, Tang Y.

J Am Chem Soc. 2009 Jun 24;131(24):8388-9. doi: 10.1021/ja903203g.

18.
19.

Planning and developing a diagnostic imaging center.

Meehan MJ, Whelton DG.

J Am Coll Radiol. 2004 Dec;1(12):916-25. Review.

PMID:
17411733
20.

Aging negatively skews macrophage TLR2- and TLR4-mediated pro-inflammatory responses without affecting the IL-2-stimulated pathway.

Boehmer ED, Meehan MJ, Cutro BT, Kovacs EJ.

Mech Ageing Dev. 2005 Dec;126(12):1305-13. Epub 2005 Sep 8.

PMID:
16154177
21.

Trends in thoracic radiology over a decade at a large academic medical center.

Wittram C, Meehan MJ, Halpern EF, Shepard JA, McLoud TC, Thrall JH.

J Thorac Imaging. 2004 Jul;19(3):164-70.

PMID:
15273612
22.

Ethical awareness and healthcare professionals.

Holmes PA, Meehan MJ.

J Pastoral Care. 1998 Spring;52(1):33-40.

PMID:
10178814
23.

The constitutionality of physician-assisted suicide: the cases and issues before the US Supreme Court.

Meehan MJ.

Cleve Clin J Med. 1997 Jan;64(1):13-5. No abstract available.

24.
25.

Policy statements: do not resuscitate, care of the hopelessly ill, and brain death. Ethics Committee of the Cleveland Clinic Foundation.

Rogers LR, Orlowski JP, Meehan MJ, Vinicky JK.

Cleve Clin J Med. 1990 Jan-Feb;57(1):29-34. No abstract available.

26.

Locomotor activity in the Tyr-1 mutant of Drosophila melanogaster.

Meehan MJ, Wilson R.

Behav Genet. 1987 Sep;17(5):503-12. No abstract available.

PMID:
3122718
27.

Serum vitamin B12 levels in pregnant women.

Temperley IJ, Meehan MJ, Gatenby PB.

J Obstet Gynaecol Br Commonw. 1968 May;75(5):511-6. No abstract available.

PMID:
5742695
28.

Serum folic acid levels in pregnancy and their relationship to megaloblastic marrow change.

Temperley IJ, Meehan MJ, Gatenby PB.

Br J Haematol. 1968 Jan;14(1):13-9. No abstract available.

PMID:
5634628

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