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Items: 1 to 50 of 75

1.

Latency, Integration, and Reactivation of Human Herpesvirus-6.

Pantry SN, Medveczky PG.

Viruses. 2017 Jul 24;9(7). pii: E194. doi: 10.3390/v9070194. Review.

2.

Is inherited human herpesvirus 6 the perpetrator behind some cases of chronic fatigue syndrome?

Lum E, Medveczky MM, Medveczky PG.

Future Microbiol. 2014;9(4):433-6. doi: 10.2217/fmb.14.11. No abstract available.

PMID:
24810341
3.

Classification of HHV-6A and HHV-6B as distinct viruses.

Ablashi D, Agut H, Alvarez-Lafuente R, Clark DA, Dewhurst S, DiLuca D, Flamand L, Frenkel N, Gallo R, Gompels UA, Höllsberg P, Jacobson S, Luppi M, Lusso P, Malnati M, Medveczky P, Mori Y, Pellett PE, Pritchett JC, Yamanishi K, Yoshikawa T.

Arch Virol. 2014 May;159(5):863-70. doi: 10.1007/s00705-013-1902-5. Epub 2013 Nov 6. Review.

4.

Persistent human herpesvirus-6 infection in patients with an inherited form of the virus.

Pantry SN, Medveczky MM, Arbuckle JH, Luka J, Montoya JG, Hu J, Renne R, Peterson D, Pritchett JC, Ablashi DV, Medveczky PG.

J Med Virol. 2013 Nov;85(11):1940-6. doi: 10.1002/jmv.23685. Epub 2013 Jul 25.

5.

Mapping the telomere integrated genome of human herpesvirus 6A and 6B.

Arbuckle JH, Pantry SN, Medveczky MM, Prichett J, Loomis KS, Ablashi D, Medveczky PG.

Virology. 2013 Jul 20;442(1):3-11. doi: 10.1016/j.virol.2013.03.030. Epub 2013 May 4.

6.

Antiviral therapy of two patients with chromosomally-integrated human herpesvirus-6A presenting with cognitive dysfunction.

Montoya JG, Neely MN, Gupta S, Lunn MR, Loomis KS, Pritchett JC, Polsky B, Medveczky PG.

J Clin Virol. 2012 Sep;55(1):40-5. doi: 10.1016/j.jcv.2012.05.016. Epub 2012 Jul 5.

PMID:
22770640
7.

Chromosomally integrated human herpesvirus 6: questions and answers.

Pellett PE, Ablashi DV, Ambros PF, Agut H, Caserta MT, Descamps V, Flamand L, Gautheret-Dejean A, Hall CB, Kamble RT, Kuehl U, Lassner D, Lautenschlager I, Loomis KS, Luppi M, Lusso P, Medveczky PG, Montoya JG, Mori Y, Ogata M, Pritchett JC, Rogez S, Seto E, Ward KN, Yoshikawa T, Razonable RR.

Rev Med Virol. 2012 May;22(3):144-55. doi: 10.1002/rmv.715. Epub 2011 Nov 4. Review.

8.

The molecular biology of human herpesvirus-6 latency and telomere integration.

Arbuckle JH, Medveczky PG.

Microbes Infect. 2011 Aug;13(8-9):731-41. doi: 10.1016/j.micinf.2011.03.006. Epub 2011 Mar 31. Review.

9.

Review, part 1: Human herpesvirus-6-basic biology, diagnostic testing, and antiviral efficacy.

Flamand L, Komaroff AL, Arbuckle JH, Medveczky PG, Ablashi DV.

J Med Virol. 2010 Sep;82(9):1560-8. doi: 10.1002/jmv.21839. Review. No abstract available.

PMID:
20648610
10.

The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro.

Arbuckle JH, Medveczky MM, Luka J, Hadley SH, Luegmayr A, Ablashi D, Lund TC, Tolar J, De Meirleir K, Montoya JG, Komaroff AL, Ambros PF, Medveczky PG.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5563-8. doi: 10.1073/pnas.0913586107. Epub 2010 Mar 8.

12.

Epigenetic regulation of Kaposi's sarcoma-associated herpesvirus replication.

Pantry SN, Medveczky PG.

Semin Cancer Biol. 2009 Jun;19(3):153-7. doi: 10.1016/j.semcancer.2009.02.010. Epub 2009 Feb 21. Review.

13.

Identification of mitochondrial genome concatemers in AIDS-associated lymphomas and lymphoid cell lines.

Bedoya F, Medveczky MM, Lund TC, Perl A, Horvath J, Jett SD, Medveczky PG.

Leuk Res. 2009 Nov;33(11):1499-504. doi: 10.1016/j.leukres.2009.03.012. Epub 2009 Apr 11.

14.

Proteolytic activation of human pancreatitis-associated protein is required for peptidoglycan binding and bacterial aggregation.

Medveczky P, Szmola R, Sahin-Tóth M.

Biochem J. 2009 May 13;420(2):335-43. doi: 10.1042/BJ20090005. Erratum in: Biochem J. 2009 Aug 1;421(3):483.

15.

Probing conformational plasticity of the activation domain of trypsin: the role of glycine hinges.

Gombos L, Kardos J, Patthy A, Medveczky P, Szilágyi L, Málnási-Csizmadia A, Gráf L.

Biochemistry. 2008 Feb 12;47(6):1675-84. doi: 10.1021/bi701454e. Epub 2008 Jan 15.

PMID:
18193894
16.

Visible light induces matrix metalloproteinase-9 expression in rat eye.

Papp AM, Nyilas R, Szepesi Z, Lorincz ML, Takács E, Abrahám I, Szilágyi N, Tóth J, Medveczky P, Szilágyi L, Juhász G, Juhász G.

J Neurochem. 2007 Dec;103(6):2224-33. Epub 2007 Sep 11.

17.

Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression.

Németh AL, Medveczky P, Tóth J, Siklódi E, Schlett K, Patthy A, Palkovits M, Ovádi J, Tõkési N, Németh P, Szilágyi L, Gráf L.

FEBS J. 2007 Mar;274(6):1610-20.

18.

Human trypsin(ogen) 4-like immunoreactivity in the white matter of the cerebral cortex and the spinal cord.

Gallatz K, Medveczky P, Németh P, Szilágyi L, Gráf L, Palkovits M.

Ideggyogy Sz. 2007 Mar 30;60(3-4):118-23.

PMID:
17451051
19.

Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.

Focher F, Lossani A, Verri A, Spadari S, Maioli A, Gambino JJ, Wright GE, Eberle R, Black DH, Medveczky P, Medveczky M, Shugar D.

Antimicrob Agents Chemother. 2007 Jun;51(6):2028-34. Epub 2007 Apr 16.

20.

Site directed mutagenesis at position 193 of human trypsin 4 alters the rate of conformational change during activation: role of local internal viscosity in protein dynamics.

Tóth J, Simon Z, Medveczky P, Gombos L, Jelinek B, Szilágyi L, Gráf L, Málnási-Csizmadia A.

Proteins. 2007 Jun 1;67(4):1119-27.

PMID:
17436323
21.

Regional distribution of human trypsinogen 4 in human brain at mRNA and protein level.

Tóth J, Siklódi E, Medveczky P, Gallatz K, Németh P, Szilágyi L, Gráf L, Palkovits M.

Neurochem Res. 2007 Sep;32(9):1423-33. Epub 2007 Apr 4.

PMID:
17406981
22.

Thermodynamic analysis reveals structural rearrangement during the acylation step in human trypsin 4 on 4-methylumbelliferyl 4-guanidinobenzoate substrate analogue.

Tóth J, Gombos L, Simon Z, Medveczky P, Szilágyi L, Gráf L, Málnási-Csizmadia A.

J Biol Chem. 2006 May 5;281(18):12596-602. Epub 2006 Feb 21.

23.

Myelin basic protein, an autoantigen in multiple sclerosis, is selectively processed by human trypsin 4.

Medveczky P, Antal J, Patthy A, Kékesi K, Juhász G, Szilágyi L, Gráf L.

FEBS Lett. 2006 Jan 23;580(2):545-52. Epub 2005 Dec 29.

24.

Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro.

Medveczky MM, Sherwood TA, Klein TW, Friedman H, Medveczky PG.

BMC Med. 2004 Sep 15;2:34.

27.
28.

The herpesvirus saimiri tip484 and tip488 proteins both stimulate lck tyrosine protein kinase activity in vivo and in vitro.

Kjellen P, Amdjadi K, Lund TC, Medveczky PG, Sefton BM.

Virology. 2002 Jun 5;297(2):281-8.

29.

Genetic requirements for the episomal maintenance of oncogenic herpesvirus genomes.

Collins CM, Medveczky PG.

Adv Cancer Res. 2002;84:155-74. Review.

PMID:
11883526
30.

Activation of the Lck tyrosine protein kinase by the Herpesvirus saimiri tip protein involves two binding interactions.

Hartley DA, Amdjadi K, Hurley TR, Lund TC, Medveczky PG, Sefton BM.

Virology. 2000 Oct 25;276(2):339-48.

31.

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.

Zhang Y, Turkson J, Carter-Su C, Smithgall T, Levitzki A, Kraker A, Krolewski JJ, Medveczky P, Jove R.

J Biol Chem. 2000 Aug 11;275(32):24935-44.

32.

The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activity.

Lund TC, Coleman C, Horvath E, Sefton BM, Jove R, Medveczky MM, Medveczky PG.

Cell Signal. 1999 Nov;11(11):789-96.

PMID:
10617281
33.

Activation of the lck tyrosine-protein kinase by the binding of the tip protein of herpesvirus saimiri in the absence of regulatory tyrosine phosphorylation.

Hartley DA, Hurley TR, Hardwick JS, Lund TC, Medveczky PG, Sefton BM.

J Biol Chem. 1999 Jul 16;274(29):20056-9.

34.
35.

The Lck binding domain of herpesvirus saimiri tip-484 constitutively activates Lck and STAT3 in T cells.

Lund TC, Prator PC, Medveczky MM, Medveczky PG.

J Virol. 1999 Feb;73(2):1689-94.

36.

Identification of kaposin (open reading frame K12) as a human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus) transforming gene.

Muralidhar S, Pumfery AM, Hassani M, Sadaie MR, Kishishita M, Brady JN, Doniger J, Medveczky P, Rosenthal LJ.

J Virol. 1998 Jun;72(6):4980-8. Erratum in: J Virol 1999 Mar;73(3):2568.

37.

In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.

Medveczky MM, Horvath E, Lund T, Medveczky PG.

AIDS. 1997 Sep;11(11):1327-32.

PMID:
9302441
38.

Activation of STAT transcription factors by herpesvirus Saimiri Tip-484 requires p56lck.

Lund TC, Garcia R, Medveczky MM, Jove R, Medveczky PG.

J Virol. 1997 Sep;71(9):6677-82.

39.

Human Herpesvirus 8 DNA in Visceral Kaposi's Sarcoma of AIDS and Other Immunocompromised Patients in Hungary.

Nagy K, Horvath A, Medveczky M, Szabo Z, Toth A, Szende B, Yangco BG, Medveczky P.

Cancer Control. 1997 Jan;4(1):60-64. No abstract available.

PMID:
10763005
40.
42.
43.
44.
45.

Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines.

Crute JJ, Lehman IR, Gambino J, Yang TF, Medveczky P, Medveczky M, Khan NN, Mulder C, Monroe J, Wright GE.

J Med Chem. 1995 May 12;38(10):1820-5.

PMID:
7752206
46.

Haloanilino derivatives of pyrimidines, purines, and purine nucleoside analogs: synthesis and activity against human cytomegalovirus.

Medveczky M, Yang TF, Gambino J, Medveczky P, Wright GE.

J Med Chem. 1995 May 12;38(10):1811-9.

PMID:
7752205
47.

Expression of IL-2 and IL-4 in T lymphocytes transformed by herpesvirus saimiri.

Chou CS, Medveczky MM, Geck P, Vercelli D, Medveczky PG.

Virology. 1995 Apr 20;208(2):418-26.

48.

A polycistronic transcript in transformed cells encodes the dihydrofolate reductase of herpesvirus saimiri.

Whitaker S, Geck P, Medveczky MM, Cus J, Kung SH, Lund T, Medveczky PG.

Virus Genes. 1995;10(2):163-72.

PMID:
8560776
49.

Induction of a herpesvirus saimiri small RNA AU binding factor (AUBF70) activity and lymphokine mRNAs by T cell mitogens.

Chou CS, Geck P, Medveczky MM, Hernandez OM, Medveczky PG.

Arch Virol. 1995;140(3):415-35.

PMID:
7733817
50.

Herpesvirus saimiri small RNA and interleukin-4 mRNA AUUUA repeats compete for sequence-specific factors including a novel 70K protein.

Geck P, Medveczky MM, Chou CS, Brown A, Cus J, Medveczky PG.

J Gen Virol. 1994 Sep;75 ( Pt 9):2293-301. Erratum in: J Gen Virol 1994 Dec;75(Pt 12):3688.

PMID:
8077927

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