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Items: 1 to 50 of 125

1.

Methylprednisolone: Likely an Effective Treatment in Acute Respiratory Distress Syndrome.

Meduri GU, Rochwerg B, Annane D, Pastores SM; Corticosteroid Guideline Task Force of SCCM and ESICM.

Crit Care Med. 2019 Apr;47(4):e374-e375. doi: 10.1097/CCM.0000000000003572. No abstract available.

PMID:
30882439
2.

Prolonged low-dose methylprednisolone treatment is highly effective in reducing duration of mechanical ventilation and mortality in patients with ARDS.

Meduri GU, Siemieniuk RAC, Ness RA, Seyler SJ.

J Intensive Care. 2018 Aug 24;6:53. doi: 10.1186/s40560-018-0321-9. eCollection 2018.

3.

Prolonged corticosteroid treatment in acute respiratory distress syndrome: impact on mortality and ventilator-free days.

Meduri GU, Rochwerg B, Annane D, Pastores SM; Corticosteroid Guideline Task Force of SCCM and ESICM.

Crit Care. 2018 May 24;22(1):135. doi: 10.1186/s13054-018-2007-z. No abstract available.

4.

An Exploratory Reanalysis of the Randomized Trial on Efficacy of Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome.

Meduri GU, Bridges L, Siemieniuk RAC, Kocak M.

Crit Care Med. 2018 Jun;46(6):884-891. doi: 10.1097/CCM.0000000000003021.

PMID:
29432350
5.

Genome-Wide Association Study in African Americans with Acute Respiratory Distress Syndrome Identifies the Selectin P Ligand Gene as a Risk Factor.

Bime C, Pouladi N, Sammani S, Batai K, Casanova N, Zhou T, Kempf CL, Sun X, Camp SM, Wang T, Kittles RA, Lussier YA, Jones TK, Reilly JP, Meyer NJ, Christie JD, Karnes JH, Gonzalez-Garay M, Christiani DC, Yates CR, Wurfel MM, Meduri GU, Garcia JGN.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1421-1432. doi: 10.1164/rccm.201705-0961OC.

6.

Dysregulated Systemic Inflammation Favors Bacterial Growth and Development of Nosocomial Infections.

Meduri GU, Umberger R.

Am J Respir Crit Care Med. 2018 Apr 15;197(8):1092. doi: 10.1164/rccm.201709-1867LE. No abstract available.

PMID:
29216435
7.

Corticosteroids in Patients Hospitalized With Community-Acquired Pneumonia: Systematic Review and Individual Patient Data Metaanalysis.

Briel M, Spoorenberg SMC, Snijders D, Torres A, Fernandez-Serrano S, Meduri GU, Gabarr├║s A, Blum CA, Confalonieri M, Kasenda B, Siemieniuk RAC, Boersma W, Bos WJW, Christ-Crain M; Ovidius Study Group; Capisce Study Group; STEP Study Group.

Clin Infect Dis. 2018 Jan 18;66(3):346-354. doi: 10.1093/cid/cix801.

PMID:
29020323
8.

Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

Annane D, Pastores SM, Arlt W, Balk RA, Beishuizen A, Briegel J, Carcillo J, Christ-Crain M, Cooper MS, Marik PE, Meduri GU, Olsen KM, Rochwerg B, Rodgers SC, Russell JA, Van den Berghe G.

Intensive Care Med. 2017 Dec;43(12):1781-1792. doi: 10.1007/s00134-017-4914-x. Epub 2017 Sep 21. Review.

PMID:
28940017
9.

Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

Annane D, Pastores SM, Arlt W, Balk RA, Beishuizen A, Briegel J, Carcillo J, Christ-Crain M, Cooper MS, Marik PE, Meduri GU, Olsen KM, Rochwerg B, Rodgers SC, Russell JA, Van den Berghe G.

Crit Care Med. 2017 Dec;45(12):2089-2098. doi: 10.1097/CCM.0000000000002724.

PMID:
28938251
10.

Prolonged glucocorticoid treatment in acute respiratory distress syndrome.

Meduri GU, Siemieniuk RAC.

Lancet. 2017 Apr 15;389(10078):1516. doi: 10.1016/S0140-6736(17)30952-2. No abstract available.

PMID:
28422024
11.

Temporal Changes in Microrna Expression in Blood Leukocytes from Patients with the Acute Respiratory Distress Syndrome.

Narute P, Seam N, Tropea M, Logun C, Cai R, Sun J, Shelhamer JH, Meduri GU, Suffredini AF.

Shock. 2017 Jun;47(6):688-695. doi: 10.1097/SHK.0000000000000806.

12.

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome: results of a randomized controlled trial.

Tongyoo S, Permpikul C, Mongkolpun W, Vattanavanit V, Udompanturak S, Kocak M, Meduri GU.

Crit Care. 2016 Oct 15;20(1):329.

13.

Prolonged Glucocorticoid Treatment in ARDS: Impact on Intensive Care Unit-Acquired Weakness.

Meduri GU, Schwingshackl A, Hermans G.

Front Pediatr. 2016 Aug 2;4:69. doi: 10.3389/fped.2016.00069. eCollection 2016. Review.

14.

Rationale for Prolonged Glucocorticoid Use in Pediatric ARDS: What the Adults Can Teach Us.

Schwingshackl A, Meduri GU.

Front Pediatr. 2016 Jun 14;4:58. doi: 10.3389/fped.2016.00058. eCollection 2016. Review.

15.

Plasma Biomarker Analysis in Pediatric ARDS: Generating Future Framework from a Pilot Randomized Control Trial of Methylprednisolone: A Framework for Identifying Plasma Biomarkers Related to Clinical Outcomes in Pediatric ARDS.

Kimura D, Saravia J, Rovnaghi CR, Meduri GU, Schwingshackl A, Cormier SA, Anand KJ.

Front Pediatr. 2016 Mar 31;4:31. doi: 10.3389/fped.2016.00031. eCollection 2016.

16.

Diagnostic workup for ARDS patients.

Papazian L, Calfee CS, Chiumello D, Luyt CE, Meyer NJ, Sekiguchi H, Matthay MA, Meduri GU.

Intensive Care Med. 2016 May;42(5):674-685. doi: 10.1007/s00134-016-4324-5. Epub 2016 Mar 23. Review.

PMID:
27007111
17.

Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature.

Meduri GU, Bridges L, Shih MC, Marik PE, Siemieniuk RAC, Kocak M.

Intensive Care Med. 2016 May;42(5):829-840. doi: 10.1007/s00134-015-4095-4. Epub 2015 Oct 27. Review.

PMID:
26508525
18.

Corticosteroids in pediatric ARDS: all cards on the table.

Schwingshackl A, Meduri GU, Kimura D, Cormier SA, Anand KJ.

Intensive Care Med. 2015 Nov;41(11):2036-7. doi: 10.1007/s00134-015-4027-3. Epub 2015 Sep 10. No abstract available.

19.

Diffuse alveolar damage in nonresolving ARDS provides support for prolonged glucocorticoid treatment.

Meduri GU.

Intensive Care Med. 2015 Jun;41(6):1164-5. doi: 10.1007/s00134-015-3797-y. Epub 2015 May 14. No abstract available.

PMID:
25971378
20.

Exaggerated plasma interleukin 6, interleukin 10, and subsequent development of health care-associated infections in patients with sepsis.

Umberger R, Thompson CL, Cashion AK, Kuhl D, Wan J, Yates CR, Muthiah MP, Meduri GU.

Dimens Crit Care Nurs. 2015 Mar-Apr;34(2):100-11. doi: 10.1097/DCC.0000000000000098.

PMID:
25650495
21.

Double-blind, placebo-controlled pilot randomized trial of methylprednisolone infusion in pediatric acute respiratory distress syndrome.

Drago BB, Kimura D, Rovnaghi CR, Schwingshackl A, Rayburn M, Meduri GU, Anand KJ.

Pediatr Crit Care Med. 2015 Mar;16(3):e74-81. doi: 10.1097/PCC.0000000000000349.

PMID:
25634565
22.

Understanding ARDS-associated fibroproliferation.

Meduri GU, Eltorky MA.

Intensive Care Med. 2015 Mar;41(3):517-20. doi: 10.1007/s00134-014-3613-0. Epub 2015 Jan 8. Review. No abstract available.

PMID:
25567380
23.

Is prolonged low-dose glucocorticoid treatment beneficial in community-acquired pneumonia?

Confalonieri M, Annane D, Antonaglia C, Santagiuliana M, Borriello EM, Meduri GU.

Curr Infect Dis Rep. 2013 Apr;15(2):158-66. doi: 10.1007/s11908-013-0322-8.

PMID:
23371407
24.

Improving the 2007 Infectious Disease Society of America/American Thoracic Society severe community-acquired pneumonia criteria to predict intensive care unit admission.

Sibila O, Meduri GU, Mortensen EM, Anzueto A, Laserna E, Fernandez JF, El-Sohl A, Restrepo MI.

J Crit Care. 2013 Jun;28(3):284-90. doi: 10.1016/j.jcrc.2012.09.010. Epub 2012 Dec 21.

25.

Acute clinical deterioration with increased systemic inflammation as a risk factor for depression: an alternative interpretation of the data.

Meduri GU, Shih MC.

Am J Psychiatry. 2012 Aug;169(8):867; author reply 867-8. doi: 10.1176/appi.ajp.2012.12040498. No abstract available.

PMID:
22854931
26.

Effects of methylprednisolone infusion on markers of inflammation, coagulation, and angiogenesis in early acute respiratory distress syndrome.

Seam N, Meduri GU, Wang H, Nylen ES, Sun J, Schultz MJ, Tropea M, Suffredini AF.

Crit Care Med. 2012 Feb;40(2):495-501. doi: 10.1097/CCM.0b013e318232da5e.

PMID:
21983371
27.

Management of patients hospitalised with community-acquired pneumonia: dexamethasone reduces length of stay by 1 day.

Meduri GU, Confalonieri M.

Evid Based Med. 2012 Apr;17(2):51-2. doi: 10.1136/ebm.2011.100154. Epub 2011 Sep 26. No abstract available.

PMID:
21949254
28.

Glucocorticoid treatment in acute lung injury and acute respiratory distress syndrome.

Marik PE, Meduri GU, Rocco PR, Annane D.

Crit Care Clin. 2011 Jul;27(3):589-607. doi: 10.1016/j.ccc.2011.05.007. Review.

PMID:
21742218
29.

Corticosteroid treatment in severe community-acquired pneumonia: duration of treatment affects control of systemic inflammation and clinical improvement.

Nawab QU, Golden E, Confalonieri M, Umberger R, Meduri GU.

Intensive Care Med. 2011 Sep;37(9):1553-4. doi: 10.1007/s00134-011-2274-5. Epub 2011 Jun 18. No abstract available.

PMID:
21688102
30.

Glucocorticoid treatment in community-acquired pneumonia.

Confalonieri M, Meduri GU.

Lancet. 2011 Jun 11;377(9782):1982-4. doi: 10.1016/S0140-6736(11)60777-0. Epub 2011 Jun 1. No abstract available.

PMID:
21636121
31.

One-year outcomes of community-acquired and healthcare-associated pneumonia in the Veterans Affairs Healthcare System.

Hsu JL, Siroka AM, Smith MW, Holodniy M, Meduri GU.

Int J Infect Dis. 2011 Jun;15(6):e382-7. doi: 10.1016/j.ijid.2011.02.002. Epub 2011 Mar 9.

32.

Evidence-based support for prolonged glucocorticoid treatment in acute lung injury/acute respiratory distress syndrome.

Meduri GU, Annane D, Marik PE.

Crit Care Med. 2011 Jan;39(1):225; author reply 225-6. doi: 10.1097/CCM.0b013e3181fa0bb1. No abstract available.

PMID:
21178555
33.

Rapid induction of autoantibodies during ARDS and septic shock.

Burbelo PD, Seam N, Groot S, Ching KH, Han BL, Meduri GU, Iadarola MJ, Suffredini AF.

J Transl Med. 2010 Oct 14;8:97. doi: 10.1186/1479-5876-8-97.

34.

Glucocorticoid treatment in community-acquired pneumonia without severe sepsis: no evidence of efficacy.

Meduri GU, Bell WA, Confalonieri M.

Am J Respir Crit Care Med. 2010 May 1;181(9):880-2. doi: 10.1164/rccm.201001-0034ED. No abstract available.

PMID:
20430924
35.

Prolonged glucocorticoid treatment and secondary prevention in acute respiratory distress syndrome.

Meduri GU, Rocco PR, Annane D, Sinclair SE.

Expert Rev Respir Med. 2010 Apr;4(2):201-10. doi: 10.1586/ers.10.2. Review.

PMID:
20406086
36.

H1N1 influenza A virus-associated acute lung injury: response to combination oseltamivir and prolonged corticosteroid treatment.

Quispe-Laime AM, Bracco JD, Barberio PA, Campagne CG, Rolfo VE, Umberger R, Meduri GU.

Intensive Care Med. 2010 Jan;36(1):33-41. doi: 10.1007/s00134-009-1727-6. Epub 2009 Nov 19.

PMID:
19924393
37.

Activation and regulation of systemic inflammation in ARDS: rationale for prolonged glucocorticoid therapy.

Meduri GU, Annane D, Chrousos GP, Marik PE, Sinclair SE.

Chest. 2009 Dec;136(6):1631-1643. doi: 10.1378/chest.08-2408. Epub 2009 Oct 3. Review.

PMID:
19801579
38.

Inter-individual variability of plasma PAF-acetylhydrolase activity in ARDS patients and PAFAH genotype.

Li S, Stuart L, Zhang Y, Meduri GU, Umberger R, Yates CR.

J Clin Pharm Ther. 2009 Aug;34(4):447-55. doi: 10.1111/j.1365-2710.2008.01014.x.

PMID:
19583678
39.

Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.

Annane D, Bellissant E, Bollaert PE, Briegel J, Confalonieri M, De Gaudio R, Keh D, Kupfer Y, Oppert M, Meduri GU.

JAMA. 2009 Jun 10;301(22):2362-75. doi: 10.1001/jama.2009.815. Review.

PMID:
19509383
40.

Prolonged glucocorticoid treatment in acute respiratory distress syndrome: Evidence supporting effectiveness and safety.

Meduri GU, Marik PE, Annane D.

Crit Care Med. 2009 May;37(5):1800-3. doi: 10.1097/CCM.0b013e31819d2b43. No abstract available.

PMID:
19373049
41.

What conclusions should be drawn between critical care physician management and patient mortality in the intensive care unit?

Marik P, Myburgh J, Annane D, Vincent JL, Pastores S, Meduri GU, Beishuizen A.

Ann Intern Med. 2008 Nov 18;149(10):770-1; author reply 772. No abstract available.

PMID:
19017603
42.

Corticosteroids for community-acquired pneumonia: time to act!

Annane D, Meduri GU.

Crit Care. 2008;12(4):166. doi: 10.1186/cc6940. Epub 2008 Jul 14.

43.

Critical illness-related corticosteroid insufficiency and community-acquired pneumonia: back to the future!

Annane D, Meduri GU, Marik P.

Eur Respir J. 2008 Jun;31(6):1150-2. doi: 10.1183/09031936.00040908. No abstract available.

44.

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine.

Marik PE, Pastores SM, Annane D, Meduri GU, Sprung CL, Arlt W, Keh D, Briegel J, Beishuizen A, Dimopoulou I, Tsagarakis S, Singer M, Chrousos GP, Zaloga G, Bokhari F, Vogeser M; American College of Critical Care Medicine.

Crit Care Med. 2008 Jun;36(6):1937-49. doi: 10.1097/CCM.0b013e31817603ba.

PMID:
18496365
45.

Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature.

Meduri GU, Marik PE, Chrousos GP, Pastores SM, Arlt W, Beishuizen A, Bokhari F, Zaloga G, Annane D.

Intensive Care Med. 2008 Jan;34(1):61-9. Epub 2007 Nov 14.

PMID:
18000649
46.

Corticosteroids in ARDS: a counterpoint.

Meduri GU, Marik PE, Pastores SM, Annane D.

Chest. 2007 Sep;132(3):1093-4; author reply 1094. No abstract available.

PMID:
17873207
47.

Acute lung injury and acute respiratory distress syndrome.

Meduri GU, Marik PE, Pastores SM, Annane D.

Lancet. 2007 Aug 4;370(9585):384; author reply 384-5. No abstract available.

PMID:
17679007
48.

Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations.

Gao L, Flores C, Fan-Ma S, Miller EJ, Moitra J, Moreno L, Wadgaonkar R, Simon B, Brower R, Sevransky J, Tuder RM, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Ye SQ, Barnes KC, Garcia JG.

Transl Res. 2007 Jul;150(1):18-29. Epub 2007 May 25.

49.

Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial.

Meduri GU, Golden E, Freire AX, Taylor E, Zaman M, Carson SJ, Gibson M, Umberger R.

Chest. 2007 Apr;131(4):954-63.

PMID:
17426195
50.

Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006.

Antonelli M, Levy M, Andrews PJ, Chastre J, Hudson LD, Manthous C, Meduri GU, Moreno RP, Putensen C, Stewart T, Torres A.

Intensive Care Med. 2007 Apr;33(4):575-90.

PMID:
17285286

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