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Items: 1 to 50 of 65

1.

Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy.

Di Pilato M, Kim EY, Cadilha BL, Prüßmann JN, Nasrallah MN, Seruggia D, Usmani SM, Misale S, Zappulli V, Carrizosa E, Mani V, Ligorio M, Warner RD, Medoff BD, Marangoni F, Villani AC, Mempel TR.

Nature. 2019 Jun;570(7759):112-116. doi: 10.1038/s41586-019-1215-2. Epub 2019 May 15.

PMID:
31092922
2.

Quantitative assessment of airway remodelling and response to allergen in asthma.

Adams DC, Miller AJ, Applegate MB, Cho JL, Hamilos DL, Chee A, Holz JA, Szabari MV, Hariri LP, Harris RS, Griffith JW, Luster AD, Medoff BD, Suter MJ.

Respirology. 2019 Mar 7. doi: 10.1111/resp.13521. [Epub ahead of print]

PMID:
30845351
3.

HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis.

Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS.

Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021.

4.

Chronic Obstructive Pulmonary Disease: Back to the Basics.

Cho JL, Medoff BD.

Am J Respir Crit Care Med. 2018 Nov 15;198(10):1241-1242. doi: 10.1164/rccm.201806-1148ED. No abstract available.

PMID:
30011221
5.

CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata.

Causton B, Pardo-Saganta A, Gillis J, Discipio K, Kooistra T, Rajagopal J, Xavier RJ, Cho JL, Medoff BD.

Am J Respir Cell Mol Biol. 2018 Dec;59(6):684-694. doi: 10.1165/rcmb.2017-0181OC.

PMID:
29958012
6.

The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.

Knipe RS, Probst CK, Lagares D, Franklin A, Spinney JJ, Brazee PL, Grasberger P, Zhang L, Black KE, Sakai N, Shea BS, Liao JK, Medoff BD, Tager AM.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):471-481. doi: 10.1165/rcmb.2017-0075OC.

7.

Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography.

Adams DC, Pahlevaninezhad H, Szabari MV, Cho JL, Hamilos DL, Kesimer M, Boucher RC, Luster AD, Medoff BD, Suter MJ.

Biomed Opt Express. 2017 Sep 26;8(10):4729-4741. doi: 10.1364/BOE.8.004729. eCollection 2017 Oct 1.

8.

Standardization and quality control for high-dimensional mass cytometry studies of human samples.

Kleinsteuber K, Corleis B, Rashidi N, Nchinda N, Lisanti A, Cho JL, Medoff BD, Kwon D, Walker BD.

Cytometry A. 2016 Oct;89(10):903-913. doi: 10.1002/cyto.a.22935. Epub 2016 Aug 30.

9.

Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.

Cho JL, Ling MF, Adams DC, Faustino L, Islam SA, Afshar R, Griffith JW, Harris RS, Ng A, Radicioni G, Ford AA, Han AK, Xavier R, Kwok WW, Boucher R, Moon JJ, Hamilos DL, Kesimer M, Suter MJ, Medoff BD, Luster AD.

Sci Transl Med. 2016 Oct 5;8(359):359ra132.

10.

Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo.

Adams DC, Hariri LP, Miller AJ, Wang Y, Cho JL, Villiger M, Holz JA, Szabari MV, Hamilos DL, Scott Harris R, Griffith JW, Bouma BE, Luster AD, Medoff BD, Suter MJ.

Sci Transl Med. 2016 Oct 5;8(359):359ra131.

11.

Allergic Non-Asthmatic Adults Have Regional Pulmonary Responses to Segmental Allergen Challenge.

Kelly VJ, Winkler T, Venegas JG, Kone M, Hamilos DL, Afshar R, Cho JL, Luster AD, Medoff BD, Harris RS.

PLoS One. 2015 Dec 7;10(12):e0143976. doi: 10.1371/journal.pone.0143976. eCollection 2015.

12.

CARMA3 Is Critical for the Initiation of Allergic Airway Inflammation.

Causton B, Ramadas RA, Cho JL, Jones K, Pardo-Saganta A, Rajagopal J, Xavier RJ, Medoff BD.

J Immunol. 2015 Jul 15;195(2):683-94. doi: 10.4049/jimmunol.1402983. Epub 2015 Jun 3.

13.

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.

Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ.

Elife. 2015 May 22;4. doi: 10.7554/eLife.05920.

14.

Lung T cells in HIV infection. Driven to exhaustion?

Cho JL, Medoff BD.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):370-1. doi: 10.1164/rccm.201501-0011ED. No abstract available.

PMID:
25679103
15.

Dedifferentiation of committed epithelial cells into stem cells in vivo.

Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J.

Nature. 2013 Nov 14;503(7475):218-23. doi: 10.1038/nature12777. Epub 2013 Nov 6.

16.

ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection.

Wu Q, Gardiner GJ, Berry E, Wagner SR, Lu T, Clay BS, Moore TV, Ferreira CM, Williams JW, Luster AD, Medoff BD, Cannon JL, Sperling AI, Shilling RA.

PLoS One. 2013 Aug 13;8(8):e72955. doi: 10.1371/journal.pone.0072955. eCollection 2013.

17.

The role of CARMA1 in T cells.

Roche MI, Ramadas RA, Medoff BD.

Crit Rev Immunol. 2013;33(3):219-43. Review.

18.

Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation.

Afshar R, Strassner JP, Seung E, Causton B, Cho JL, Harris RS, Hamilos DL, Medoff BD, Luster AD.

J Allergy Clin Immunol. 2013 Jun;131(6):1644-52. doi: 10.1016/j.jaci.2013.03.002. Epub 2013 Apr 28.

19.

IL-36α exerts pro-inflammatory effects in the lungs of mice.

Ramadas RA, Ewart SL, Iwakura Y, Medoff BD, LeVine AM.

PLoS One. 2012;7(9):e45784. doi: 10.1371/journal.pone.0045784. Epub 2012 Sep 20.

20.

Enhanced Tim3 activity improves survival after influenza infection.

Cho JL, Roche MI, Sandall B, Brass AL, Seed B, Xavier RJ, Medoff BD.

J Immunol. 2012 Sep 15;189(6):2879-89. doi: 10.4049/jimmunol.1102483. Epub 2012 Aug 8.

21.

Fat, fire and muscle--the role of adiponectin in pulmonary vascular inflammation and remodeling.

Medoff BD.

Pulm Pharmacol Ther. 2013 Aug;26(4):420-6. doi: 10.1016/j.pupt.2012.06.006. Epub 2012 Jun 26. Review.

PMID:
22750271
22.

Obesity and pulmonary arterial hypertension: Is adiponectin the molecular link between these conditions?

Summer R, Walsh K, Medoff BD.

Pulm Circ. 2011 Oct-Dec;1(4):440-7. doi: 10.4103/2045-8932.93542.

23.

Volumetric optical frequency domain imaging of pulmonary pathology with precise correlation to histopathology.

Hariri LP, Applegate MB, Mino-Kenudson M, Mark EJ, Medoff BD, Luster AD, Bouma BE, Tearney GJ, Suter MJ.

Chest. 2013 Jan;143(1):64-74. doi: 10.1378/chest.11-2797.

24.

CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma.

Ramadas RA, Roche MI, Moon JJ, Ludwig T, Xavier RJ, Medoff BD.

J Immunol. 2011 Dec 15;187(12):6197-207. doi: 10.4049/jimmunol.1101348. Epub 2011 Nov 9.

25.

18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma.

Harris RS, Venegas JG, Wongviriyawong C, Winkler T, Kone M, Musch G, Vidal Melo MF, de Prost N, Hamilos DL, Afshar R, Cho J, Luster AD, Medoff BD.

J Nucl Med. 2011 Nov;52(11):1713-20. doi: 10.2967/jnumed.110.086355. Epub 2011 Oct 11. Erratum in: J Nucl Med. 2014 Apr;55(4):698.

26.

Eosinophils are necessary for pulmonary arterial remodeling in a mouse model of eosinophilic inflammation-induced pulmonary hypertension.

Weng M, Baron DM, Bloch KD, Luster AD, Lee JJ, Medoff BD.

Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L927-36. doi: 10.1152/ajplung.00049.2011. Epub 2011 Sep 9.

27.

Variant alveolar lipoproteinosis: a syndrome with distinct clinical and pathological features.

Nishino M, Medoff BD, Mark EJ, Matsubara O, O'Donnell WJ, Currier PF, Kradin RL.

Pathol Int. 2011 Sep;61(9):509-17. doi: 10.1111/j.1440-1827.2011.02710.x.

PMID:
21884300
28.

Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection.

Seung E, Cho JL, Sparwasser T, Medoff BD, Luster AD.

J Immunol. 2011 Jun 15;186(12):6830-8. doi: 10.4049/jimmunol.1001049. Epub 2011 May 9.

29.

Adiponectin decreases pulmonary arterial remodeling in murine models of pulmonary hypertension.

Weng M, Raher MJ, Leyton P, Combs TP, Scherer PE, Bloch KD, Medoff BD.

Am J Respir Cell Mol Biol. 2011 Aug;45(2):340-7. doi: 10.1165/rcmb.2010-0316OC. Epub 2010 Nov 12.

30.

Adiponectin lowers glucose production by increasing SOGA.

Cowherd RB, Asmar MM, Alderman JM, Alderman EA, Garland AL, Busby WH, Bodnar WM, Rusyn I, Medoff BD, Tisch R, Mayer-Davis E, Swenberg JA, Zeisel SH, Combs TP.

Am J Pathol. 2010 Oct;177(4):1936-45. doi: 10.2353/ajpath.2010.100363. Epub 2010 Sep 2. Erratum in: Am J Pathol. 2011 Mar;178(3):1406. Cowerd, Rachael B [corrected to Cowherd, Rachael B].

31.

Case records of the Massachusetts General Hospital. Case 16-2010. A 48-year-old man with a cough and pain in the left shoulder.

Medoff BD, Abbott GF, Louissaint A Jr.

N Engl J Med. 2010 May 27;362(21):2013-22. doi: 10.1056/NEJMcpc1002114. No abstract available.

PMID:
20505181
32.

Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography.

Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R.

Opt Lett. 2010 Apr 1;35(7):1088-90. doi: 10.1364/OL.35.001088.

33.

Interleukin-1 family member 9 stimulates chemokine production and neutrophil influx in mouse lungs.

Ramadas RA, Ewart SL, Medoff BD, LeVine AM.

Am J Respir Cell Mol Biol. 2011 Feb;44(2):134-45. doi: 10.1165/rcmb.2009-0315OC. Epub 2010 Mar 18.

34.

Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling.

Medoff BD, Okamoto Y, Leyton P, Weng M, Sandall BP, Raher MJ, Kihara S, Bloch KD, Libby P, Luster AD.

Am J Respir Cell Mol Biol. 2009 Oct;41(4):397-406. doi: 10.1165/rcmb.2008-0415OC. Epub 2009 Jan 23.

35.

Differential requirement for CARMA1 in agonist-selected T-cell development.

Medoff BD, Sandall BP, Landry A, Nagahama K, Mizoguchi A, Luster AD, Xavier RJ.

Eur J Immunol. 2009 Jan;39(1):78-84. doi: 10.1002/eji.200838734.

36.

CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation.

Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD.

J Immunol. 2009 Jan 1;182(1):623-35.

37.

The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.

Zhou D, Medoff BD, Chen L, Li L, Zhang XF, Praskova M, Liu M, Landry A, Blumberg RS, Boussiotis VA, Xavier R, Avruch J.

Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20321-6. doi: 10.1073/pnas.0810773105. Epub 2008 Dec 10.

38.

Contribution of CCR4 and CCR8 to antigen-specific T(H)2 cell trafficking in allergic pulmonary inflammation.

Mikhak Z, Fukui M, Farsidjani A, Medoff BD, Tager AM, Luster AD.

J Allergy Clin Immunol. 2009 Jan;123(1):67-73.e3. doi: 10.1016/j.jaci.2008.09.049. Epub 2008 Dec 4.

39.

CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality.

Fadel SA, Bromley SK, Medoff BD, Luster AD.

Eur J Immunol. 2008 Dec;38(12):3376-87. doi: 10.1002/eji.200838628.

40.

Allergic asthma: a tale of many T cells.

Afshar R, Medoff BD, Luster AD.

Clin Exp Allergy. 2008 Dec;38(12):1847-57. doi: 10.1111/j.1365-2222.2008.03119.x. Review.

PMID:
19037961
41.

CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells.

Medoff BD, Landry AL, Wittbold KA, Sandall BP, Derby MC, Cao Z, Adams JC, Xavier RJ.

Am J Respir Cell Mol Biol. 2009 Mar;40(3):286-94. doi: 10.1165/rcmb.2008-0129OC. Epub 2008 Aug 28.

42.

Invasive and noninvasive ventilation in patients with asthma.

Medoff BD.

Respir Care. 2008 Jun;53(6):740-48; discussion 749-50. Review.

43.

T cell trafficking in allergic asthma: the ins and outs.

Medoff BD, Thomas SY, Luster AD.

Annu Rev Immunol. 2008;26:205-32. doi: 10.1146/annurev.immunol.26.021607.090312. Review.

PMID:
18304002
44.

Development of a novel chemokine-mediated in vivo T cell recruitment assay.

Campanella GS, Medoff BD, Manice LA, Colvin RA, Luster AD.

J Immunol Methods. 2008 Feb 29;331(1-2):127-39. doi: 10.1016/j.jim.2007.12.002. Epub 2008 Jan 9.

45.

Multiple chemokine receptors, including CCR6 and CXCR3, regulate antigen-induced T cell homing to the human asthmatic airway.

Thomas SY, Banerji A, Medoff BD, Lilly CM, Luster AD.

J Immunol. 2007 Aug 1;179(3):1901-12.

46.

Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity.

Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD.

J Immunol. 2006 Nov 15;177(10):6991-8.

47.

CARMA1 is critical for the development of allergic airway inflammation in a murine model of asthma.

Medoff BD, Seed B, Jackobek R, Zora J, Yang Y, Luster AD, Xavier R.

J Immunol. 2006 Jun 15;176(12):7272-7.

48.

CXCR3 and its ligands in a murine model of obliterative bronchiolitis: regulation and function.

Medoff BD, Wain JC, Seung E, Jackobek R, Means TK, Ginns LC, Farber JM, Luster AD.

J Immunol. 2006 Jun 1;176(11):7087-95.

49.

STAT1 in peripheral tissue differentially regulates homing of antigen-specific Th1 and Th2 cells.

Mikhak Z, Fleming CM, Medoff BD, Thomas SY, Tager AM, Campanella GS, Luster AD.

J Immunol. 2006 Apr 15;176(8):4959-67.

50.

Pathogenic T-cell recruitment into the airway in human disease.

Medoff BD, Thomas SY, Banerji A, Wain JC, Zhang H, Lilly CM, Ginns LC, Luster AD.

Ann N Y Acad Sci. 2005 Dec;1062:220-41. Review.

PMID:
16461804

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