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Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals.

Schwörer S, Becker F, Feller C, Baig AH, Köber U, Henze H, Kraus JM, Xin B, Lechel A, Lipka DB, Varghese CS, Schmidt M, Rohs R, Aebersold R, Medina KL, Kestler HA, Neri F, von Maltzahn J, Tümpel S, Rudolph KL.

Nature. 2016 Dec 15;540(7633):428-432. doi: 10.1038/nature20603. Epub 2016 Nov 30.


Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development.

Xu Z, Gwin KA, Li Y, Medina KL.

BMC Immunol. 2016 Jun 10;17(1):16. doi: 10.1186/s12865-016-0152-1.


Overview of the immune system.

Medina KL.

Handb Clin Neurol. 2016;133:61-76. doi: 10.1016/B978-0-444-63432-0.00004-9.


Cell extrinsic alterations in splenic B cell maturation in Flt3-ligand knockout mice.

Dolence JJ, Gwin KA, Shapiro MB, Hsu FC, Shapiro VS, Medina KL.

Immun Inflamm Dis. 2015 Jun;3(2):103-17. doi: 10.1002/iid3.54. Epub 2015 Apr 15.


Stem and progenitor cell subsets are affected by JAK2 signaling and can be monitored by flow cytometry.

Iida R, Welner RS, Zhao W, Alberola-lla J, Medina KL, Zhao ZJ, Kincade PW.

PLoS One. 2014 Apr 3;9(4):e93643. doi: 10.1371/journal.pone.0093643. eCollection 2014.


Flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate B cell precursors.

Dolence JJ, Gwin KA, Shapiro MB, Medina KL.

Exp Hematol. 2014 May;42(5):380-393.e3. doi: 10.1016/j.exphem.2014.01.001. Epub 2014 Jan 18.


Separation of plasmacytoid dendritic cells from B-cell-biased lymphoid progenitor (BLP) and Pre-pro B cells using PDCA-1.

Medina KL, Tangen SN, Seaburg LM, Thapa P, Gwin KA, Shapiro VS.

PLoS One. 2013 Oct 30;8(10):e78408. doi: 10.1371/journal.pone.0078408. eCollection 2013.


RAG-1 and Ly6D independently reflect progression in the B lymphoid lineage.

Zhang Q, Esplin BL, Iida R, Garrett KP, Huang ZL, Medina KL, Kincade PW.

PLoS One. 2013 Aug 30;8(8):e72397. doi: 10.1371/journal.pone.0072397. eCollection 2013.


Hoxa9 and Flt3 signaling synergistically regulate an early checkpoint in lymphopoiesis.

Gwin KA, Shapiro MB, Dolence JJ, Huang ZL, Medina KL.

J Immunol. 2013 Jul 15;191(2):745-54. doi: 10.4049/jimmunol.1203294. Epub 2013 Jun 14.


Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors.

Gwin K, Dolence JJ, Shapiro MB, Medina KL.

BMC Immunol. 2013 Jan 30;14:5. doi: 10.1186/1471-2172-14-5.


CD86 is expressed on murine hematopoietic stem cells and denotes lymphopoietic potential.

Shimazu T, Iida R, Zhang Q, Welner RS, Medina KL, Alberola-Lla J, Kincade PW.

Blood. 2012 May 24;119(21):4889-97. doi: 10.1182/blood-2011-10-388736. Epub 2012 Feb 27.


Gender effects on amygdala morphometry in adolescent marijuana users.

McQueeny T, Padula CB, Price J, Medina KL, Logan P, Tapert SF.

Behav Brain Res. 2011 Oct 10;224(1):128-34. doi: 10.1016/j.bbr.2011.05.031. Epub 2011 Jun 2.


Impact of Adolescent Alcohol and Drug Use on Neuropsychological Functioning in Young Adulthood: 10-Year Outcomes.

Hanson KL, Medina KL, Padula CB, Tapert SF, Brown SA.

J Child Adolesc Subst Abuse. 2011 Jan 1;20(2):135-154.


Threshold levels of Flt3-ligand are required for the generation and survival of lymphoid progenitors and B-cell precursors.

Dolence JJ, Gwin K, Frank E, Medina KL.

Eur J Immunol. 2011 Feb;41(2):324-34. doi: 10.1002/eji.201040710.


The influence of recency of use on fMRI response during spatial working memory in adolescent marijuana users.

Schweinsburg AD, Schweinsburg BC, Medina KL, McQueeny T, Brown SA, Tapert SF.

J Psychoactive Drugs. 2010 Sep;42(3):401-12.


Hoxa9 regulates Flt3 in lymphohematopoietic progenitors.

Gwin K, Frank E, Bossou A, Medina KL.

J Immunol. 2010 Dec 1;185(11):6572-83. doi: 10.4049/jimmunol.0904203. Epub 2010 Oct 22.


Longitudinal study of cognition among adolescent marijuana users over three weeks of abstinence.

Hanson KL, Winward JL, Schweinsburg AD, Medina KL, Brown SA, Tapert SF.

Addict Behav. 2010 Nov;35(11):970-6. doi: 10.1016/j.addbeh.2010.06.012. Epub 2010 Jun 13.


Hippocampal volumes in adolescents with and without a family history of alcoholism.

Hanson KL, Medina KL, Nagel BJ, Spadoni AD, Gorlick A, Tapert SF.

Am J Drug Alcohol Abuse. 2010 May;36(3):161-7. doi: 10.3109/00952991003736397.


Abnormal cerebellar morphometry in abstinent adolescent marijuana users.

Medina KL, Nagel BJ, Tapert SF.

Psychiatry Res. 2010 May 30;182(2):152-9. doi: 10.1016/j.pscychresns.2009.12.004. Epub 2010 Apr 21.


Bi-directional activation between mesenchymal stem cells and CLL B-cells: implication for CLL disease progression.

Ding W, Nowakowski GS, Knox TR, Boysen JC, Maas ML, Schwager SM, Wu W, Wellik LE, Dietz AB, Ghosh AK, Secreto CR, Medina KL, Shanafelt TD, Zent CS, Call TG, Kay NE.

Br J Haematol. 2009 Nov;147(4):471-83. doi: 10.1111/j.1365-2141.2009.07868.x. Epub 2009 Sep 8.


Prefrontal cortex morphometry in abstinent adolescent marijuana users: subtle gender effects.

Medina KL, McQueeny T, Nagel BJ, Hanson KL, Yang TT, Tapert SF.

Addict Biol. 2009 Sep;14(4):457-68. doi: 10.1111/j.1369-1600.2009.00166.x. Epub 2009 Jul 24.


Sleep architecture in adolescent marijuana and alcohol users during acute and extended abstinence.

Cohen-Zion M, Drummond SP, Padula CB, Winward J, Kanady J, Medina KL, Tapert SF.

Addict Behav. 2009 Nov;34(11):976-9. doi: 10.1016/j.addbeh.2009.05.011. Epub 2009 May 23.


Prefrontal cortex volumes in adolescents with alcohol use disorders: unique gender effects.

Medina KL, McQueeny T, Nagel BJ, Hanson KL, Schweinsburg AD, Tapert SF.

Alcohol Clin Exp Res. 2008 Mar;32(3):386-94. doi: 10.1111/j.1530-0277.2007.00602.x.


Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.

Pongubala JM, Northrup DL, Lancki DW, Medina KL, Treiber T, Bertolino E, Thomas M, Grosschedl R, Allman D, Singh H.

Nat Immunol. 2008 Feb;9(2):203-15. doi: 10.1038/ni1555. Epub 2008 Jan 6.


Neuropsychological functioning in adolescent marijuana users: subtle deficits detectable after a month of abstinence.

Medina KL, Hanson KL, Schweinsburg AD, Cohen-Zion M, Nagel BJ, Tapert SF.

J Int Neuropsychol Soc. 2007 Sep;13(5):807-20.


Depressive symptoms in adolescents: associations with white matter volume and marijuana use.

Medina KL, Nagel BJ, Park A, McQueeny T, Tapert SF.

J Child Psychol Psychiatry. 2007 Jun;48(6):592-600.


Gene regulatory networks that orchestrate the development of B lymphocyte precursors.

Singh H, Pongubala JM, Medina KL.

Adv Exp Med Biol. 2007;596:57-62. Review.


Effects of alcohol and combined marijuana and alcohol use during adolescence on hippocampal volume and asymmetry.

Medina KL, Schweinsburg AD, Cohen-Zion M, Nagel BJ, Tapert SF.

Neurotoxicol Teratol. 2007 Jan-Feb;29(1):141-52. Epub 2006 Dec 12.


Anxiety, depression, and behavioral symptoms of executive dysfunction in ecstasy users: contributions of polydrug use.

Medina KL, Shear PK.

Drug Alcohol Depend. 2007 Mar 16;87(2-3):303-11. Epub 2006 Oct 30.


Age-related changes in prefrontal white matter volume across adolescence.

Nagel BJ, Medina KL, Yoshii J, Schweinsburg AD, Moadab I, Tapert SF.

Neuroreport. 2006 Sep 18;17(13):1427-31.


Developmental normative data for the Corsi Block-tapping task.

Farrell Pagulayan K, Busch RM, Medina KL, Bartok JA, Krikorian R.

J Clin Exp Neuropsychol. 2006 Aug;28(6):1043-52.


Memory functioning in polysubstance dependent women.

Medina KL, Shear PK, Schafer J.

Drug Alcohol Depend. 2006 Oct 1;84(3):248-55. Epub 2006 Apr 3.


Gene regulatory networks orchestrating B cell fate specification, commitment, and differentiation.

Medina KL, Singh H.

Curr Top Microbiol Immunol. 2005;290:1-14. Review.


Ecstasy (MDMA) exposure and neuropsychological functioning: a polydrug perspective.

Medina KL, Shear PK, Corcoran K.

J Int Neuropsychol Soc. 2005 Oct;11(6):753-65.


Regulation of interleukin 7-dependent immunoglobulin heavy-chain variable gene rearrangements by transcription factor STAT5.

Bertolino E, Reddy K, Medina KL, Parganas E, Ihle J, Singh H.

Nat Immunol. 2005 Aug;6(8):836-43. Epub 2005 Jul 17.


Genetic networks that regulate B lymphopoiesis.

Medina KL, Singh H.

Curr Opin Hematol. 2005 May;12(3):203-9. Review.


Contingent gene regulatory networks and B cell fate specification.

Singh H, Medina KL, Pongubala JM.

Proc Natl Acad Sci U S A. 2005 Apr 5;102(14):4949-53. Epub 2005 Mar 23. Review.


Early lymphoid progenitors in mouse and man are highly sensitive to glucocorticoids.

Igarashi H, Medina KL, Yokota T, Rossi MI, Sakaguchi N, Comp PC, Kincade PW.

Int Immunol. 2005 May;17(5):501-11. Epub 2005 Mar 3.


Assembling a gene regulatory network for specification of the B cell fate.

Medina KL, Pongubala JM, Reddy KL, Lancki DW, Dekoter R, Kieslinger M, Grosschedl R, Singh H.

Dev Cell. 2004 Oct;7(4):607-17.


Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription.

Maier H, Ostraat R, Gao H, Fields S, Shinton SA, Medina KL, Ikawa T, Murre C, Singh H, Hardy RR, Hagman J.

Nat Immunol. 2004 Oct;5(10):1069-77. Epub 2004 Sep 12.


Cognitive functioning and length of abstinence in polysubstance dependent men.

Medina KL, Shear PK, Schafer J, Armstrong TG, Dyer P.

Arch Clin Neuropsychol. 2004 Mar;19(2):245-58.


Adiponectin, a fat cell product, influences the earliest lymphocyte precursors in bone marrow cultures by activation of the cyclooxygenase-prostaglandin pathway in stromal cells.

Yokota T, Meka CS, Kouro T, Medina KL, Igarashi H, Takahashi M, Oritani K, Funahashi T, Tomiyama Y, Matsuzawa Y, Kincade PW.

J Immunol. 2003 Nov 15;171(10):5091-9.


IRF-4,8 orchestrate the pre-B-to-B transition in lymphocyte development.

Lu R, Medina KL, Lancki DW, Singh H.

Genes Dev. 2003 Jul 15;17(14):1703-8. Epub 2003 Jun 27.


Lymphoid lineage cells in adult murine bone marrow diverge from those of other blood cells at an early, hormone-sensitive stage.

Kincade PW, Igarashi H, Medina KL, Kouro T, Yokota T, Rossi MI, Owen JJ, Garrett KP, Sun XH, Sakaguchi N.

Semin Immunol. 2002 Dec;14(6):385-94. Review.


B lymphopoiesis is active throughout human life, but there are developmental age-related changes.

Rossi MI, Yokota T, Medina KL, Garrett KP, Comp PC, Schipul AH Jr, Kincade PW.

Blood. 2003 Jan 15;101(2):576-84. Epub 2002 Aug 29.


Self-administration of alcohol before and after a public speaking challenge by individuals with social phobia.

Abrams K, Kushner MG, Medina KL, Voight A.

Psychol Addict Behav. 2002 Jun;16(2):121-8. Erratum in: Psychol Addict Behav 2002 Sep;16(3):211.


Paracrine regulation of fat cell formation in bone marrow cultures via adiponectin and prostaglandins.

Yokota T, Meka CS, Medina KL, Igarashi H, Comp PC, Takahashi M, Nishida M, Oritani K, Miyagawa J, Funahashi T, Tomiyama Y, Matsuzawa Y, Kincade PW.

J Clin Invest. 2002 May;109(10):1303-10.


Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development.

Kosak ST, Skok JA, Medina KL, Riblet R, Le Beau MM, Fisher AG, Singh H.

Science. 2002 Apr 5;296(5565):158-62.


Relatively normal human lymphopoiesis but rapid turnover of newly formed B cells in transplanted nonobese diabetic/SCID mice.

Rossi MI, Medina KL, Garrett K, Kolar G, Comp PC, Shultz LD, Capra JD, Wilson P, Schipul A, Kincade PW.

J Immunol. 2001 Sep 15;167(6):3033-42.


The pharmacologic and expectancy effects of alcohol on social anxiety in individuals with social phobia.

Abrams K, Kushner M, Medina KL, Voight A.

Drug Alcohol Depend. 2001 Oct 1;64(2):219-31.


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