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Items: 1 to 50 of 108

1.

The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.

Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A.

Nat Cell Biol. 2019 Oct;21(10):1248-1260. doi: 10.1038/s41556-019-0397-z. Epub 2019 Oct 1.

PMID:
31576060
2.

Glycoprotein Ib clustering in platelets can be inhibited by alpha-linolenic acid as revealed by cryo-electron tomography.

Stivala S, Sorrentino S, Gobbato S, Bonetti NR, Camici GG, Lüscher TF, Medalia O, Beer JH.

Haematologica. 2019 Aug 22. pii: haematol.2019.220988. doi: 10.3324/haematol.2019.220988. [Epub ahead of print]

3.

The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.

Qi C, Sorrentino S, Medalia O, Korkhov VM.

Science. 2019 Apr 26;364(6438):389-394. doi: 10.1126/science.aav0778.

PMID:
31023924
4.

Cellular and Structural Studies of Eukaryotic Cells by Cryo-Electron Tomography.

Weber MS, Wojtynek M, Medalia O.

Cells. 2019 Jan 16;8(1). pii: E57. doi: 10.3390/cells8010057. Review.

5.

Tiopronin-Protected Gold Nanoparticles as a Potential Marker for Cryo-EM and Tomography.

Dahan I, Sorrentino S, Boujemaa-Paterski R, Medalia O.

Structure. 2018 Oct 2;26(10):1408-1413.e3. doi: 10.1016/j.str.2018.06.009. Epub 2018 Aug 2.

6.

Insight into the functional organization of nuclear lamins in health and disease.

Tatli M, Medalia O.

Curr Opin Cell Biol. 2018 Oct;54:72-79. doi: 10.1016/j.ceb.2018.05.001. Epub 2018 May 23. Review.

PMID:
29800922
7.

Profilin 1-mediated cytoskeletal rearrangements regulate integrin function in mouse platelets.

Stritt S, Birkholz I, Beck S, Sorrentino S, Sapra KT, Viaud J, Heck J, Gaits-Iacovoni F, Schulze H, Du X, Hartwig JH, Braun A, Bender M, Medalia O, Nieswandt B.

Blood Adv. 2018 May 8;2(9):1040-1045. doi: 10.1182/bloodadvances.2017014001. No abstract available.

8.

Morphometric analysis of spread platelets identifies integrin αIIbβ3-specific contractile phenotype.

Lickert S, Sorrentino S, Studt JD, Medalia O, Vogel V, Schoen I.

Sci Rep. 2018 Apr 3;8(1):5428. doi: 10.1038/s41598-018-23684-w.

9.

Conformational states during vinculin unlocking differentially regulate focal adhesion properties.

Chorev DS, Volberg T, Livne A, Eisenstein M, Martins B, Kam Z, Jockusch BM, Medalia O, Sharon M, Geiger B.

Sci Rep. 2018 Feb 9;8(1):2693. doi: 10.1038/s41598-018-21006-8.

10.

Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.

Schmid M, Ernst P, Honegger A, Suomalainen M, Zimmermann M, Braun L, Stauffer S, Thom C, Dreier B, Eibauer M, Kipar A, Vogel V, Greber UF, Medalia O, Plückthun A.

Nat Commun. 2018 Jan 31;9(1):450. doi: 10.1038/s41467-017-02707-6.

11.

Nuclear Lamins: Thin Filaments with Major Functions.

de Leeuw R, Gruenbaum Y, Medalia O.

Trends Cell Biol. 2018 Jan;28(1):34-45. doi: 10.1016/j.tcb.2017.08.004. Epub 2017 Sep 8. Review.

PMID:
28893461
12.

The structure of lamin filaments in somatic cells as revealed by cryo-electron tomography.

Turgay Y, Medalia O.

Nucleus. 2017 Sep 3;8(5):475-481. doi: 10.1080/19491034.2017.1337622. Epub 2017 Jun 21. Review.

13.

Phosphorylation-Induced Mechanical Regulation of Intrinsically Disordered Neurofilament Proteins.

Malka-Gibor E, Kornreich M, Laser-Azogui A, Doron O, Zingerman-Koladko I, Harapin J, Medalia O, Beck R.

Biophys J. 2017 Mar 14;112(5):892-900. doi: 10.1016/j.bpj.2016.12.050.

14.

The molecular architecture of lamins in somatic cells.

Turgay Y, Eibauer M, Goldman AE, Shimi T, Khayat M, Ben-Harush K, Dubrovsky-Gaupp A, Sapra KT, Goldman RD, Medalia O.

Nature. 2017 Mar 9;543(7644):261-264. doi: 10.1038/nature21382. Epub 2017 Mar 1.

15.

The assembly of C. elegans lamins into macroscopic fibers.

Zingerman-Koladko I, Khayat M, Harapin J, Shoseyov O, Gruenbaum Y, Salman A, Medalia O, Ben-Harush K.

J Mech Behav Biomed Mater. 2016 Oct;63:35-43. doi: 10.1016/j.jmbbm.2016.05.037. Epub 2016 Jun 4.

PMID:
27341289
16.

Toward correlating structure and mechanics of platelets.

Sorrentino S, Studt JD, Horev MB, Medalia O, Sapra KT.

Cell Adh Migr. 2016 Sep 2;10(5):568-575. Epub 2016 Apr 22. Review.

17.

Impaired mechanical response of an EDMD mutation leads to motility phenotypes that are repaired by loss of prenylation.

Zuela N, Zwerger M, Levin T, Medalia O, Gruenbaum Y.

J Cell Sci. 2016 May 1;129(9):1781-91. doi: 10.1242/jcs.184309. Epub 2016 Mar 31.

18.

Architecture and Characteristics of Bacterial Nanotubes.

Dubey GP, Malli Mohan GB, Dubrovsky A, Amen T, Tsipshtein S, Rouvinski A, Rosenberg A, Kaganovich D, Sherman E, Medalia O, Ben-Yehuda S.

Dev Cell. 2016 Feb 22;36(4):453-61. doi: 10.1016/j.devcel.2016.01.013.

19.

Insights into the gate of the nuclear pore complex.

Zwerger M, Eibauer M, Medalia O.

Nucleus. 2016;7(1):1-7. doi: 10.1080/19491034.2015.1130197. Epub 2016 Feb 22.

20.

Cellular structural biology as revealed by cryo-electron tomography.

Irobalieva RN, Martins B, Medalia O.

J Cell Sci. 2016 Feb 1;129(3):469-76. doi: 10.1242/jcs.171967. Epub 2016 Jan 19. Review.

21.

The macromolecular architecture of platelet-derived microparticles.

Tamir A, Sorrentino S, Motahedeh S, Shai E, Dubrovsky A, Dahan I, Eibauer M, Studt JD, Sapra KT, Varon D, Medalia O.

J Struct Biol. 2016 Mar;193(3):181-187. doi: 10.1016/j.jsb.2015.12.013. Epub 2016 Jan 6.

PMID:
26767592
22.

Altering lamina assembly reveals lamina-dependent and -independent functions for A-type lamins.

Zwerger M, Roschitzki-Voser H, Zbinden R, Denais C, Herrmann H, Lammerding J, Grütter MG, Medalia O.

J Cell Sci. 2015 Oct 1;128(19):3607-20. doi: 10.1242/jcs.171843. Epub 2015 Aug 14.

23.

Structure and gating of the nuclear pore complex.

Eibauer M, Pellanda M, Turgay Y, Dubrovsky A, Wild A, Medalia O.

Nat Commun. 2015 Jun 26;6:7532. doi: 10.1038/ncomms8532.

24.

Structural analysis of multicellular organisms with cryo-electron tomography.

Harapin J, Börmel M, Sapra KT, Brunner D, Kaech A, Medalia O.

Nat Methods. 2015 Jul;12(7):634-6. doi: 10.1038/nmeth.3401. Epub 2015 May 11.

PMID:
25961413
25.

Developments in cryo-electron tomography for in situ structural analysis.

Dubrovsky A, Sorrentino S, Harapin J, Sapra KT, Medalia O.

Arch Biochem Biophys. 2015 Sep 1;581:78-85. doi: 10.1016/j.abb.2015.04.006. Epub 2015 Apr 25. Review.

PMID:
25921875
26.

Roll, adhere, spread and contract: structural mechanics of platelet function.

Sorrentino S, Studt JD, Medalia O, Tanuj Sapra K.

Eur J Cell Biol. 2015 Mar-Apr;94(3-4):129-38. doi: 10.1016/j.ejcb.2015.01.001. Epub 2015 Jan 20. Review.

PMID:
25655000
27.

Lamins: the structure and protein complexes.

Gruenbaum Y, Medalia O.

Curr Opin Cell Biol. 2015 Feb;32:7-12. doi: 10.1016/j.ceb.2014.09.009. Epub 2014 Oct 13. Review.

PMID:
25460776
28.

Differential effect of actomyosin relaxation on the dynamic properties of focal adhesion proteins.

Lavelin I, Wolfenson H, Patla I, Henis YI, Medalia O, Volberg T, Livne A, Kam Z, Geiger B.

PLoS One. 2013 Sep 9;8(9):e73549. doi: 10.1371/journal.pone.0073549. eCollection 2013. Erratum in: PLoS One. 2014;9(2):e90269.

29.

Structural analysis of supramolecular assemblies by cryo-electron tomography.

Harapin J, Eibauer M, Medalia O.

Structure. 2013 Sep 3;21(9):1522-30. doi: 10.1016/j.str.2013.08.003. Review.

30.

Experimental analysis of co-evolution within protein complexes: the yeast exosome as a model.

Sandler I, Medalia O, Aharoni A.

Proteins. 2013 Nov;81(11):1997-2006. doi: 10.1002/prot.24360. Epub 2013 Aug 23.

PMID:
23852635
31.

The role of integrin-linked kinase in the molecular architecture of focal adhesions.

Elad N, Volberg T, Patla I, Hirschfeld-Warneken V, Grashoff C, Spatz JP, Fässler R, Geiger B, Medalia O.

J Cell Sci. 2013 Sep 15;126(Pt 18):4099-107. doi: 10.1242/jcs.120295. Epub 2013 Jul 10.

32.

From lamins to lamina: a structural perspective.

Zwerger M, Medalia O.

Histochem Cell Biol. 2013 Jul;140(1):3-12. doi: 10.1007/s00418-013-1104-y. Epub 2013 Jun 7. Review.

PMID:
23744527
33.

Advances in tomography: probing the molecular architecture of cells.

Fridman K, Mader A, Zwerger M, Elia N, Medalia O.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):736-42. doi: 10.1038/nrm3453. Epub 2012 Oct 10. Review.

PMID:
23047735
34.

The human nuclear pore complex as revealed by cryo-electron tomography.

Maimon T, Elad N, Dahan I, Medalia O.

Structure. 2012 Jun 6;20(6):998-1006. doi: 10.1016/j.str.2012.03.025. Epub 2012 May 24.

35.

Functional architecture of the nuclear pore complex.

Grossman E, Medalia O, Zwerger M.

Annu Rev Biophys. 2012;41:557-84. doi: 10.1146/annurev-biophys-050511-102328. Review.

PMID:
22577827
36.

Special issue on electron tomography.

Medalia O, Frangakis A.

J Struct Biol. 2012 May;178(2):75. doi: 10.1016/j.jsb.2012.03.004. Epub 2012 Mar 20. No abstract available.

PMID:
22445943
37.

Unravelling the lamina network.

Zwerger M, Medalia O.

Nat Rev Mol Cell Biol. 2012 Feb 15;13(3):140. doi: 10.1038/nrm3291. No abstract available.

PMID:
22334141
38.

Outcome of the first electron microscopy validation task force meeting.

Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, Rossmann MG, Schmid MF, Schröder GF, Steven AC, Stokes DL, Westbrook JD, Wriggers W, Yang H, Young J, Berman HM, Chiu W, Kleywegt GJ, Lawson CL.

Structure. 2012 Feb 8;20(2):205-14. doi: 10.1016/j.str.2011.12.014.

39.

Reconstructing adhesion structures in tissues by cryo-electron tomography of vitrified frozen sections.

Bokstad M, Sabanay H, Dahan I, Geiger B, Medalia O.

J Struct Biol. 2012 May;178(2):76-83. doi: 10.1016/j.jsb.2011.10.013. Epub 2011 Nov 7.

PMID:
22085747
40.

Filaments assembly of ectopically expressed Caenorhabditis elegans lamin within Xenopus oocytes.

Grossman E, Dahan I, Stick R, Goldberg MW, Gruenbaum Y, Medalia O.

J Struct Biol. 2012 Jan;177(1):113-8. doi: 10.1016/j.jsb.2011.11.002. Epub 2011 Nov 9.

PMID:
22085746
41.

Structural and physiological phenotypes of disease-linked lamin mutations in C. elegans.

Bank EM, Ben-Harush K, Feinstein N, Medalia O, Gruenbaum Y.

J Struct Biol. 2012 Jan;177(1):106-12. doi: 10.1016/j.jsb.2011.10.009. Epub 2011 Nov 7.

PMID:
22079399
42.

Assembly and breakdown of microtubules within the midbody.

Tamir A, Elad N, Medalia O.

Commun Integr Biol. 2011 Sep;4(5):552-3. doi: 10.4161/cib.4.5.16050. Epub 2011 Sep 1.

43.

Automated segmentation of electron tomograms for a quantitative description of actin filament networks.

Rigort A, Günther D, Hegerl R, Baum D, Weber B, Prohaska S, Medalia O, Baumeister W, Hege HC.

J Struct Biol. 2012 Jan;177(1):135-44. doi: 10.1016/j.jsb.2011.08.012. Epub 2011 Sep 1.

PMID:
21907807
44.

Cryo-electron tomography: gaining insight into cellular processes by structural approaches.

Yahav T, Maimon T, Grossman E, Dahan I, Medalia O.

Curr Opin Struct Biol. 2011 Oct;21(5):670-7. doi: 10.1016/j.sbi.2011.07.004. Epub 2011 Aug 2. Review.

PMID:
21813274
45.

A laminopathic mutation disrupting lamin filament assembly causes disease-like phenotypes in Caenorhabditis elegans.

Bank EM, Ben-Harush K, Wiesel-Motiuk N, Barkan R, Feinstein N, Lotan O, Medalia O, Gruenbaum Y.

Mol Biol Cell. 2011 Aug 1;22(15):2716-28. doi: 10.1091/mbc.E11-01-0064. Epub 2011 Jun 8.

46.

Perspective on the metazoan nuclear pore complex.

Maimon T, Medalia O.

Nucleus. 2010 Sep-Oct;1(5):383-6. doi: 10.4161/nucl.1.5.12332.

47.

Microtubule organization in the final stages of cytokinesis as revealed by cryo-electron tomography.

Elad N, Abramovitch S, Sabanay H, Medalia O.

J Cell Sci. 2011 Jan 15;124(Pt 2):207-15. doi: 10.1242/jcs.073486.

48.

Cryoelectron tomography of eukaryotic cells.

Mader A, Elad N, Medalia O.

Methods Enzymol. 2010;483:245-65. doi: 10.1016/S0076-6879(10)83012-5.

PMID:
20888478
49.

Frontiers of microscopy-based research into cell-matrix adhesions.

Medalia O, Geiger B.

Curr Opin Cell Biol. 2010 Oct;22(5):659-68. doi: 10.1016/j.ceb.2010.08.006. Epub 2010 Sep 6. Review.

PMID:
20822892
50.

Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography.

Patla I, Volberg T, Elad N, Hirschfeld-Warneken V, Grashoff C, Fässler R, Spatz JP, Geiger B, Medalia O.

Nat Cell Biol. 2010 Sep;12(9):909-15. doi: 10.1038/ncb2095. Epub 2010 Aug 8. Erratum in: Nat Cell Biol. 2010 Sep;12(9). doi: 10.1038/ncb2095.

PMID:
20694000

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