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Items: 1 to 50 of 184

1.

Structural analysis of urinary light chains and proteomic analysis of hyaline tubular casts in light chain associated kidney disorders.

Reiter T, Knafl D, Agis H, Mechtler K, Wagner L, Winnicki W.

PeerJ. 2019 Oct 2;7:e7819. doi: 10.7717/peerj.7819. eCollection 2019.

2.

The H3 histone chaperone NASPSIM 3 escorts CenH3 in Arabidopsis.

Le Goff S, Nur Keçeli B, Jerabkova H, Heckmann S, Rutten T, Cotterell S, Schubert V, Roitinger E, Mechtler K, Franklin FCH, Tatout C, Houben A, Geelen D, Probst AV, Lermontova I.

Plant J. 2019 Aug 29. doi: 10.1111/tpj.14518. [Epub ahead of print]

PMID:
31463991
3.

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.

Batki J, Schnabl J, Wang J, Handler D, Andreev VI, Stieger CE, Novatchkova M, Lampersberger L, Kauneckaite K, Xie W, Mechtler K, Patel DJ, Brennecke J.

Nat Struct Mol Biol. 2019 Aug;26(8):720-731. doi: 10.1038/s41594-019-0270-6. Epub 2019 Aug 5.

PMID:
31384064
4.

N-terminal β-strand underpins biochemical specialization of an ATG8 isoform.

Zess EK, Jensen C, Cruz-Mireles N, De la Concepcion JC, Sklenar J, Stephani M, Imre R, Roitinger E, Hughes R, Belhaj K, Mechtler K, Menke FLH, Bozkurt T, Banfield MJ, Kamoun S, Maqbool A, Dagdas YF.

PLoS Biol. 2019 Jul 22;17(7):e3000373. doi: 10.1371/journal.pbio.3000373. eCollection 2019 Jul.

5.

Absolute quantification of cohesin, CTCF and their regulators in human cells.

Holzmann J, Politi AZ, Nagasaka K, Hantsche-Grininger M, Walther N, Koch B, Fuchs J, Dürnberger G, Tang W, Ladurner R, Stocsits RR, Busslinger GA, Novák B, Mechtler K, Davidson IF, Ellenberg J, Peters JM.

Elife. 2019 Jun 17;8. pii: e46269. doi: 10.7554/eLife.46269.

6.

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.

Sdelci S, Rendeiro AF, Rathert P, You W, Lin JG, Ringler A, Hofstätter G, Moll HP, Gürtl B, Farlik M, Schick S, Klepsch F, Oldach M, Buphamalai P, Schischlik F, Májek P, Parapatics K, Schmidl C, Schuster M, Penz T, Buckley DL, Hudecz O, Imre R, Wang SY, Maric HM, Kralovics R, Bennett KL, Müller AC, Mechtler K, Menche J, Bradner JE, Winter GE, Klavins K, Casanova E, Bock C, Zuber J, Kubicek S.

Nat Genet. 2019 Jun;51(6):990-998. doi: 10.1038/s41588-019-0413-z. Epub 2019 May 27.

PMID:
31133746
7.

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

Iacobucci C, Piotrowski C, Aebersold R, Amaral BC, Andrews P, Bernfur K, Borchers C, Brodie NI, Bruce JE, Cao Y, Chaignepain S, Chavez JD, Claverol S, Cox J, Davis T, Degliesposti G, Dong MQ, Edinger N, Emanuelsson C, Gay M, Götze M, Gomes-Neto F, Gozzo FC, Gutierrez C, Haupt C, Heck AJR, Herzog F, Huang L, Hoopmann MR, Kalisman N, Klykov O, Kukačka Z, Liu F, MacCoss MJ, Mechtler K, Mesika R, Moritz RL, Nagaraj N, Nesati V, Neves-Ferreira AGC, Ninnis R, Novák P, O'Reilly FJ, Pelzing M, Petrotchenko E, Piersimoni L, Plasencia M, Pukala T, Rand KD, Rappsilber J, Reichmann D, Sailer C, Sarnowski CP, Scheltema RA, Schmidt C, Schriemer DC, Shi Y, Skehel JM, Slavin M, Sobott F, Solis-Mezarino V, Stephanowitz H, Stengel F, Stieger CE, Trabjerg E, Trnka M, Vilaseca M, Viner R, Xiang Y, Yilmaz S, Zelter A, Ziemianowicz D, Leitner A, Sinz A.

Anal Chem. 2019 Jun 4;91(11):6953-6961. doi: 10.1021/acs.analchem.9b00658. Epub 2019 May 22.

8.

Structure of McsB, a protein kinase for regulated arginine phosphorylation.

Suskiewicz MJ, Hajdusits B, Beveridge R, Heuck A, Vu LD, Kurzbauer R, Hauer K, Thoeny V, Rumpel K, Mechtler K, Meinhart A, Clausen T.

Nat Chem Biol. 2019 May;15(5):510-518. doi: 10.1038/s41589-019-0265-y. Epub 2019 Apr 8.

PMID:
30962626
9.

Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins.

Griss J, Stanek F, Hudecz O, Dürnberger G, Perez-Riverol Y, Vizcaíno JA, Mechtler K.

J Proteome Res. 2019 Apr 5;18(4):1477-1485. doi: 10.1021/acs.jproteome.8b00377. Epub 2019 Mar 22.

10.

Optimized Fragmentation Improves the Identification of Peptides Cross-Linked by MS-Cleavable Reagents.

Stieger CE, Doppler P, Mechtler K.

J Proteome Res. 2019 Mar 1;18(3):1363-1370. doi: 10.1021/acs.jproteome.8b00947. Epub 2019 Feb 18.

PMID:
30693776
11.

apQuant: Accurate Label-Free Quantification by Quality Filtering.

Doblmann J, Dusberger F, Imre R, Hudecz O, Stanek F, Mechtler K, Dürnberger G.

J Proteome Res. 2019 Jan 4;18(1):535-541. doi: 10.1021/acs.jproteome.8b00113. Epub 2018 Nov 2.

PMID:
30351950
12.

Reply to 'Defining distance restraints in HADDOCK'.

Orbán-Németh Z, Beveridge R, Hollenstein DM, Rampler E, Stranzl T, Hudecz O, Doblmann J, Schlögelhofer P, Mechtler K.

Nat Protoc. 2018 Jul;13(7):1503-1505. doi: 10.1038/s41596-018-0018-5. No abstract available.

PMID:
29942006
13.

Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.

Orbán-Németh Z, Beveridge R, Hollenstein DM, Rampler E, Stranzl T, Hudecz O, Doblmann J, Schlögelhofer P, Mechtler K.

Nat Protoc. 2018 Jul;13(7):1724. doi: 10.1038/s41596-018-0024-7.

PMID:
29942004
14.

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

Ivanov MP, Ladurner R, Poser I, Beveridge R, Rampler E, Hudecz O, Novatchkova M, Hériché JK, Wutz G, van der Lelij P, Kreidl E, Hutchins JR, Axelsson-Ekker H, Ellenberg J, Hyman AA, Mechtler K, Peters JM.

EMBO J. 2018 Aug 1;37(15). pii: e97150. doi: 10.15252/embj.201797150. Epub 2018 Jun 21.

15.

Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.

Sanyal S, Molnarova L, Richterova J, Huraiova B, Benko Z, Polakova S, Cipakova I, Sevcovicova A, Gaplovska-Kysela K, Mechtler K, Cipak L, Gregan J.

J Cell Sci. 2018 Jul 6;131(13). pii: jcs214924. doi: 10.1242/jcs.214924.

16.

Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stránecký V, Dürnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA.

Nat Neurosci. 2018 Aug;21(8):1139. doi: 10.1038/s41593-018-0170-9.

PMID:
29875394
17.

CharmeRT: Boosting Peptide Identifications by Chimeric Spectra Identification and Retention Time Prediction.

Dorfer V, Maltsev S, Winkler S, Mechtler K.

J Proteome Res. 2018 Aug 3;17(8):2581-2589. doi: 10.1021/acs.jproteome.7b00836. Epub 2018 Jun 28.

18.

Analysis of PNGase F-Resistant N-Glycopeptides Using SugarQb for Proteome Discoverer 2.1 Reveals Cryptic Substrate Specificities.

Stadlmann J, Hoi DM, Taubenschmid J, Mechtler K, Penninger JM.

Proteomics. 2018 Jul;18(13):e1700436. doi: 10.1002/pmic.201700436. Epub 2018 Jun 10.

19.

Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.

Orbán-Németh Z, Beveridge R, Hollenstein DM, Rampler E, Stranzl T, Hudecz O, Doblmann J, Schlögelhofer P, Mechtler K.

Nat Protoc. 2018 Mar;13(3):478-494. doi: 10.1038/nprot.2017.146. Epub 2018 Feb 8. Erratum in: Nat Protoc. 2018 Jul;13(7):1724.

20.

UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.

Hellerschmied D, Roessler M, Lehner A, Gazda L, Stejskal K, Imre R, Mechtler K, Dammermann A, Clausen T.

Nat Commun. 2018 Feb 2;9(1):484. doi: 10.1038/s41467-018-02924-7.

21.

Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

Gstrein T, Edwards A, Přistoupilová A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stránecký V, Dürnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA.

Nat Neurosci. 2018 Feb;21(2):207-217. doi: 10.1038/s41593-017-0053-5. Epub 2018 Jan 8. Erratum in: Nat Neurosci. 2018 Aug;21(8):1139.

22.

Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis.

Osman K, Yang J, Roitinger E, Lambing C, Heckmann S, Howell E, Cuacos M, Imre R, Dürnberger G, Mechtler K, Armstrong S, Franklin FCH.

Plant J. 2018 Jan;93(1):17-33. doi: 10.1111/tpj.13752. Epub 2017 Dec 2.

23.

PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search.

Dorl S, Winkler S, Mechtler K, Dorfer V.

J Proteome Res. 2018 Jan 5;17(1):290-295. doi: 10.1021/acs.jproteome.7b00563. Epub 2017 Nov 2.

PMID:
29057658
24.

TORC1 signaling exerts spatial control over microtubule dynamics by promoting nuclear export of Stu2.

van der Vaart B, Fischböck J, Mieck C, Pichler P, Mechtler K, Medema RH, Westermann S.

J Cell Biol. 2017 Nov 6;216(11):3471-3484. doi: 10.1083/jcb.201606080. Epub 2017 Sep 29.

25.

Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.

Stadlmann J, Taubenschmid J, Wenzel D, Gattinger A, Dürnberger G, Dusberger F, Elling U, Mach L, Mechtler K, Penninger JM.

Nature. 2017 Sep 28;549(7673):538-542. doi: 10.1038/nature24015. Epub 2017 Sep 20.

26.

A novel non-canonical PIP-box mediates PARG interaction with PCNA.

Kaufmann T, Grishkovskaya I, Polyansky AA, Kostrhon S, Kukolj E, Olek KM, Herbert S, Beltzung E, Mechtler K, Peterbauer T, Gotzmann J, Zhang L, Hartl M, Zagrovic B, Elsayad K, Djinovic-Carugo K, Slade D.

Nucleic Acids Res. 2017 Sep 19;45(16):9741-9759. doi: 10.1093/nar/gkx604.

27.

A vital sugar code for ricin toxicity.

Taubenschmid J, Stadlmann J, Jost M, Klokk TI, Rillahan CD, Leibbrandt A, Mechtler K, Paulson JC, Jude J, Zuber J, Sandvig K, Elling U, Marquardt T, Thiel C, Koerner C, Penninger JM.

Cell Res. 2017 Nov;27(11):1351-1364. doi: 10.1038/cr.2017.116. Epub 2017 Sep 19.

28.

Urinary neprilysin in the critically ill patient.

Pajenda S, Mechtler K, Wagner L.

BMC Nephrol. 2017 May 25;18(1):172. doi: 10.1186/s12882-017-0587-5.

29.

Proceedings of the EuBIC Winter School 2017.

Willems S, Bouyssié D, David M, Locard-Paulet M, Mechtler K, Schwämmle V, Uszkoreit J, Vaudel M, Dorfer V.

J Proteomics. 2017 May 24;161:78-80. doi: 10.1016/j.jprot.2017.04.001. Epub 2017 Apr 4.

PMID:
28385664
30.

Phosphoproteomics with Activated Ion Electron Transfer Dissociation.

Riley NM, Hebert AS, Dürnberger G, Stanek F, Mechtler K, Westphall MS, Coon JJ.

Anal Chem. 2017 Jun 20;89(12):6367-6376. doi: 10.1021/acs.analchem.7b00212. Epub 2017 Apr 17.

31.

Identification of mega-environments in Europe and effect of allelic variation at maturity E loci on adaptation of European soybean.

Kurasch AK, Hahn V, Leiser WL, Vollmann J, Schori A, Bétrix CA, Mayr B, Winkler J, Mechtler K, Aper J, Sudaric A, Pejic I, Sarcevic H, Jeanson P, Balko C, Signor M, Miceli F, Strijk P, Rietman H, Muresanu E, Djordjevic V, Pospišil A, Barion G, Weigold P, Streng S, Krön M, Würschum T.

Plant Cell Environ. 2017 May;40(5):765-778. doi: 10.1111/pce.12896. Epub 2017 Feb 18.

PMID:
28042879
32.

Corrigendum: MuSK Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop.

Camurdanoglu BZ, Hrovat C, Dürnberger G, Madalinski M, Mechtler K, Herbst R.

Sci Rep. 2016 Dec 1;6:38271. doi: 10.1038/srep38271. No abstract available.

33.

SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.

Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, Opravil S, Hudecz O, Mechtler K, Warren G, Slade D.

J Cell Sci. 2016 Dec 15;129(24):4607-4621. Epub 2016 Nov 14.

34.

Arginine phosphorylation marks proteins for degradation by a Clp protease.

Trentini DB, Suskiewicz MJ, Heuck A, Kurzbauer R, Deszcz L, Mechtler K, Clausen T.

Nature. 2016 Nov 3;539(7627):48-53. doi: 10.1038/nature20122. Epub 2016 Oct 6.

35.

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

Asaoka T, Almagro J, Ehrhardt C, Tsai I, Schleiffer A, Deszcz L, Junttila S, Ringrose L, Mechtler K, Kavirayani A, Gyenesei A, Hofmann K, Duchek P, Rittinger K, Ikeda F.

EMBO Rep. 2016 Nov;17(11):1624-1640. Epub 2016 Oct 4.

36.

Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.

Reimão-Pinto MM, Manzenreither RA, Burkard TR, Sledz P, Jinek M, Mechtler K, Ameres SL.

EMBO J. 2016 Nov 15;35(22):2417-2434. Epub 2016 Oct 11.

37.

MuSK Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop.

Camurdanoglu BZ, Hrovat C, Dürnberger G, Madalinski M, Mechtler K, Herbst R.

Sci Rep. 2016 Sep 26;6:33583. doi: 10.1038/srep33583. Erratum in: Sci Rep. 2016 Dec 01;6:38271.

38.

CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore.

Pekgöz Altunkaya G, Malvezzi F, Demianova Z, Zimniak T, Litos G, Weissmann F, Mechtler K, Herzog F, Westermann S.

Curr Biol. 2016 Sep 12;26(17):2370-8. doi: 10.1016/j.cub.2016.07.005. Epub 2016 Aug 11.

39.

A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.

Wissel S, Kieser A, Yasugi T, Duchek P, Roitinger E, Gokcezade J, Steinmann V, Gaul U, Mechtler K, Förstemann K, Knoblich JA, Neumüller RA.

G3 (Bethesda). 2016 Aug 9;6(8):2467-78. doi: 10.1534/g3.116.028571.

40.

Mechanism of APC/CCDC20 activation by mitotic phosphorylation.

Qiao R, Weissmann F, Yamaguchi M, Brown NG, VanderLinden R, Imre R, Jarvis MA, Brunner MR, Davidson IF, Litos G, Haselbach D, Mechtler K, Stark H, Schulman BA, Peters JM.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2570-8. doi: 10.1073/pnas.1604929113. Epub 2016 Apr 25.

41.

Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1".

Rampler E, Stranzl T, Orban-Nemeth Z, Hollenstein DM, Hudecz O, Schlögelhofer P, Mechtler K.

J Proteome Res. 2016 May 6;15(5):1732. doi: 10.1021/acs.jproteome.6b00257. Epub 2016 Apr 4. No abstract available.

PMID:
27043818
42.

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition.

Kiermaier E, Moussion C, Veldkamp CT, Gerardy-Schahn R, de Vries I, Williams LG, Chaffee GR, Phillips AJ, Freiberger F, Imre R, Taleski D, Payne RJ, Braun A, Förster R, Mechtler K, Mühlenhoff M, Volkman BF, Sixt M.

Science. 2016 Jan 8;351(6269):186-90. doi: 10.1126/science.aad0512. Epub 2015 Dec 10.

43.

Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1.

Rampler E, Stranzl T, Orban-Nemeth Z, Hollenstein DM, Hudecz O, Schlögelhofer P, Mechtler K.

J Proteome Res. 2015 Dec 4;14(12):5048-62. doi: 10.1021/acs.jproteome.5b00903. Epub 2015 Nov 18. Erratum in: J Proteome Res. 2016 May 6;15(5):1732.

44.

Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.

Lambing C, Osman K, Nuntasoontorn K, West A, Higgins JD, Copenhaver GP, Yang J, Armstrong SJ, Mechtler K, Roitinger E, Franklin FC.

PLoS Genet. 2015 Jul 16;11(7):e1005372. doi: 10.1371/journal.pgen.1005372. eCollection 2015 Jul.

45.

Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation.

Phadnis N, Cipak L, Polakova S, Hyppa RW, Cipakova I, Anrather D, Karvaiova L, Mechtler K, Smith GR, Gregan J.

PLoS Genet. 2015 May 20;11(5):e1005225. doi: 10.1371/journal.pgen.1005225. eCollection 2015 May. Erratum in: PLoS Genet. 2015 May;11(5):e1005343.

46.

Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation.

Iacovella MG, Golfieri C, Massari LF, Busnelli S, Pagliuca C, Dal Maschio M, Infantino V, Visintin R, Mechtler K, Ferreira-Cerca S, De Wulf P.

Nat Commun. 2015 Apr 8;6:6643. doi: 10.1038/ncomms7643.

PMID:
25851096
48.

Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.

Roitinger E, Hofer M, Köcher T, Pichler P, Novatchkova M, Yang J, Schlögelhofer P, Mechtler K.

Mol Cell Proteomics. 2015 Mar;14(3):556-71. doi: 10.1074/mcp.M114.040352. Epub 2015 Jan 5.

49.

A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.

Waidmann S, Kusenda B, Mayerhofer J, Mechtler K, Jonak C.

Plant Cell. 2014 Nov;26(11):4328-44. doi: 10.1105/tpc.114.129254. Epub 2014 Nov 11.

50.

The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes.

Mérai Z, Chumak N, García-Aguilar M, Hsieh TF, Nishimura T, Schoft VK, Bindics J, Slusarz L, Arnoux S, Opravil S, Mechtler K, Zilberman D, Fischer RL, Tamaru H.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):16166-71. doi: 10.1073/pnas.1418564111. Epub 2014 Oct 24.

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