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Items: 1 to 50 of 109

1.

Dynamin and reverse-mode sodium calcium exchanger blockade confers neuroprotection from diffuse axonal injury.

Omelchenko A, Shrirao AB, Bhattiprolu AK, Zahn JD, Schloss RS, Dickson S, Meaney DF, Boustany NN, Yarmush ML, Firestein BL.

Cell Death Dis. 2019 Sep 27;10(10):727. doi: 10.1038/s41419-019-1908-3.

2.

Primum non nocere: a call for balance when reporting on CTE.

Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH.

Lancet Neurol. 2019 Mar;18(3):231-233. doi: 10.1016/S1474-4422(19)30020-1. Epub 2019 Feb 12. No abstract available. Erratum in: Lancet Neurol. 2019 Apr;18(4):e3.

3.

A Role for Postsynaptic Density 95 and Its Binding Partners in Models of Traumatic Brain Injury.

Patel MV, Sewell E, Dickson S, Kim H, Meaney DF, Firestein BL.

J Neurotrauma. 2019 Jul 1;36(13):2129-2138. doi: 10.1089/neu.2018.6291. Epub 2019 Mar 28.

PMID:
30747034
4.

Diagnosis of traumatic brain injury using miRNA signatures in nanomagnetically isolated brain-derived extracellular vesicles.

Ko J, Hemphill M, Yang Z, Sewell E, Na YJ, Sandsmark DK, Haber M, Fisher SA, Torre EA, Svane KC, Omelchenko A, Firestein BL, Diaz-Arrastia R, Kim J, Meaney DF, Issadore D.

Lab Chip. 2018 Dec 7;18(23):3617-3630. doi: 10.1039/c8lc00672e. Epub 2018 Oct 25.

5.

Cypin: A novel target for traumatic brain injury.

Swiatkowski P, Sewell E, Sweet ES, Dickson S, Swanson RA, McEwan SA, Cuccolo N, McDonnell ME, Patel MV, Varghese N, Morrison B, Reitz AB, Meaney DF, Firestein BL.

Neurobiol Dis. 2018 Nov;119:13-25. doi: 10.1016/j.nbd.2018.07.019. Epub 2018 Jul 19.

6.

Mechanoporation is a potential indicator of tissue strain and subsequent degeneration following experimental traumatic brain injury.

LaPlaca MC, Lessing MC, Prado GR, Zhou R, Tate CC, Geddes-Klein D, Meaney DF, Zhang L.

Clin Biomech (Bristol, Avon). 2019 Apr;64:2-13. doi: 10.1016/j.clinbiomech.2018.05.016. Epub 2018 Jun 7.

PMID:
29933966
7.

Pre-Clinical Testing of Therapies for Traumatic Brain Injury.

DeWitt DS, Hawkins BE, Dixon CE, Kochanek PM, Armstead W, Bass CR, Bramlett HM, Buki A, Dietrich WD, Ferguson AR, Hall ED, Hayes RL, Hinds SR, LaPlaca MC, Long JB, Meaney DF, Mondello S, Noble-Haeusslein LJ, Poloyac SM, Prough DS, Robertson CS, Saatman KE, Shultz SR, Shear DA, Smith DH, Valadka AB, VandeVord P, Zhang L.

J Neurotrauma. 2018 Dec 1;35(23):2737-2754. doi: 10.1089/neu.2018.5778. Epub 2018 Aug 30.

PMID:
29756522
8.

Mechanical disruption of the blood-brain barrier following experimental concussion.

Johnson VE, Weber MT, Xiao R, Cullen DK, Meaney DF, Stewart W, Smith DH.

Acta Neuropathol. 2018 May;135(5):711-726. doi: 10.1007/s00401-018-1824-0. Epub 2018 Feb 19.

9.

Phosphodiesterase-4 inhibition restored hippocampal long term potentiation after primary blast.

Vogel EW 3rd, Morales FN, Meaney DF, Bass CR, Morrison B 3rd.

Exp Neurol. 2017 Jul;293:91-100. doi: 10.1016/j.expneurol.2017.03.025. Epub 2017 Mar 31.

10.

Autaptic Connections Shift Network Excitability and Bursting.

Wiles L, Gu S, Pasqualetti F, Parvesse B, Gabrieli D, Bassett DS, Meaney DF.

Sci Rep. 2017 Mar 7;7:44006. doi: 10.1038/srep44006.

11.

Primary Blast Exposure Increases Hippocampal Vulnerability to Subsequent Exposure: Reducing Long-Term Potentiation.

Effgen GB, Ong T, Nammalwar S, Ortuño AI, Meaney DF, 'Dale' Bass CR, Morrison B 3rd.

J Neurotrauma. 2016 Oct 15;33(20):1901-1912. Epub 2016 Mar 17.

12.

A Porcine Model of Traumatic Brain Injury via Head Rotational Acceleration.

Cullen DK, Harris JP, Browne KD, Wolf JA, Duda JE, Meaney DF, Margulies SS, Smith DH.

Methods Mol Biol. 2016;1462:289-324. doi: 10.1007/978-1-4939-3816-2_17.

13.

Primary Blast Injury Depressed Hippocampal Long-Term Potentiation through Disruption of Synaptic Proteins.

Vogel EW 3rd, Rwema SH, Meaney DF, Bass CR, Morrison B 3rd.

J Neurotrauma. 2017 Mar 1;34(5):1063-1073. doi: 10.1089/neu.2016.4578. Epub 2016 Oct 13.

PMID:
27573357
14.

Smartphone-enabled optofluidic exosome diagnostic for concussion recovery.

Ko J, Hemphill MA, Gabrieli D, Wu L, Yelleswarapu V, Lawrence G, Pennycooke W, Singh A, Meaney DF, Issadore D.

Sci Rep. 2016 Aug 8;6:31215. doi: 10.1038/srep31215.

15.

Primary blast injury causes cognitive impairments and hippocampal circuit alterations.

Beamer M, Tummala SR, Gullotti D, Kopil C, Gorka S, Ted Abel, Bass CR, Morrison B 3rd, Cohen AS, Meaney DF.

Exp Neurol. 2016 Sep;283(Pt A):16-28. doi: 10.1016/j.expneurol.2016.05.025. Epub 2016 May 28.

16.

Time Course and Size of Blood-Brain Barrier Opening in a Mouse Model of Blast-Induced Traumatic Brain Injury.

Hue CD, Cho FS, Cao S, Nicholls RE, Vogel Iii EW, Sibindi C, Arancio O, Dale Bass CR, Meaney DF, Morrison Iii B.

J Neurotrauma. 2016 Jul 1;33(13):1202-11. doi: 10.1089/neu.2015.4067. Epub 2015 Nov 12.

PMID:
26414212
17.

Isolated Primary Blast Inhibits Long-Term Potentiation in Organotypic Hippocampal Slice Cultures.

Vogel EW 3rd, Effgen GB, Patel TP, Meaney DF, Bass CR, Morrison B 3rd.

J Neurotrauma. 2016 Apr 1;33(7):652-61. doi: 10.1089/neu.2015.4045. Epub 2015 Dec 2.

18.

Dexamethasone potentiates in vitro blood-brain barrier recovery after primary blast injury by glucocorticoid receptor-mediated upregulation of ZO-1 tight junction protein.

Hue CD, Cho FS, Cao S, Dale Bass CR, Meaney DF, Morrison B 3rd.

J Cereb Blood Flow Metab. 2015 Jul;35(7):1191-8. doi: 10.1038/jcbfm.2015.38. Epub 2015 Mar 11.

19.

Animal models of traumatic brain injury.

Johnson VE, Meaney DF, Cullen DK, Smith DH.

Handb Clin Neurol. 2015;127:115-28. doi: 10.1016/B978-0-444-52892-6.00008-8. Review.

20.

Cellular biomechanics of central nervous system injury.

Meaney DF, Smith DH.

Handb Clin Neurol. 2015;127:105-14. doi: 10.1016/B978-0-444-52892-6.00007-6. Review.

21.

Automated quantification of neuronal networks and single-cell calcium dynamics using calcium imaging.

Patel TP, Man K, Firestein BL, Meaney DF.

J Neurosci Methods. 2015 Mar 30;243:26-38. doi: 10.1016/j.jneumeth.2015.01.020. Epub 2015 Jan 25.

22.

Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury.

Kang WH, Cao W, Graudejus O, Patel TP, Wagner S, Meaney DF, Morrison B 3rd.

J Neurotrauma. 2015 Jul 1;32(13):1011-9. doi: 10.1089/neu.2014.3667. Epub 2015 Apr 24.

23.

An open-source toolbox for automated phenotyping of mice in behavioral tasks.

Patel TP, Gullotti DM, Hernandez P, O'Brien WT, Capehart BP, Morrison B 3rd, Bass C, Eberwine JE, Abel T, Meaney DF.

Front Behav Neurosci. 2014 Oct 8;8:349. doi: 10.3389/fnbeh.2014.00349. eCollection 2014.

24.

A modified controlled cortical impact technique to model mild traumatic brain injury mechanics in mice.

Chen Y, Mao H, Yang KH, Abel T, Meaney DF.

Front Neurol. 2014 Jun 18;5:100. doi: 10.3389/fneur.2014.00100. eCollection 2014.

25.

Significant head accelerations can influence immediate neurological impairments in a murine model of blast-induced traumatic brain injury.

Gullotti DM, Beamer M, Panzer MB, Chen YC, Patel TP, Yu A, Jaumard N, Winkelstein B, Bass CR, Morrison B, Meaney DF.

J Biomech Eng. 2014 Sep;136(9):091004. doi: 10.1115/1.4027873.

PMID:
24950710
26.

Single-neuron NMDA receptor phenotype influences neuronal rewiring and reintegration following traumatic injury.

Patel TP, Ventre SC, Geddes-Klein D, Singh PK, Meaney DF.

J Neurosci. 2014 Mar 19;34(12):4200-13. doi: 10.1523/JNEUROSCI.4172-13.2014.

27.

Isolated primary blast alters neuronal function with minimal cell death in organotypic hippocampal slice cultures.

Effgen GB, Vogel EW 3rd, Lynch KA, Lobel A, Hue CD, Meaney DF, Bass CR, Morrison B 3rd.

J Neurotrauma. 2014 Jul 1;31(13):1202-10. doi: 10.1089/neu.2013.3227. Epub 2014 May 8.

PMID:
24558968
28.

The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden.

Meaney DF, Morrison B, Dale Bass C.

J Biomech Eng. 2014 Feb;136(2):021008. doi: 10.1115/1.4026364. Review.

29.

Repeated primary blast injury causes delayed recovery, but not additive disruption, in an in vitro blood-brain barrier model.

Hue CD, Cao S, Dale Bass CR, Meaney DF, Morrison B 3rd.

J Neurotrauma. 2014 May 15;31(10):951-60. doi: 10.1089/neu.2013.3149. Epub 2014 Feb 20.

PMID:
24372353
30.

Engraftment of nonintegrating neural stem cells differentially perturbs cortical activity in a dose-dependent manner.

Weerakkody TN, Patel TP, Yue C, Takano H, Anderson HC, Meaney DF, Coulter DA, Wolfe JH.

Mol Ther. 2013 Dec;21(12):2258-67. doi: 10.1038/mt.2013.163. Epub 2013 Jul 8.

31.

Blood-brain barrier dysfunction after primary blast injury in vitro.

Hue CD, Cao S, Haider SF, Vo KV, Effgen GB, Vogel E 3rd, Panzer MB, Bass CR, Meaney DF, Morrison B 3rd.

J Neurotrauma. 2013 Oct 1;30(19):1652-63. doi: 10.1089/neu.2012.2773. Epub 2013 Aug 28.

PMID:
23581482
32.

Brain injury-induced proteolysis is reduced in a novel calpastatin-overexpressing transgenic mouse.

Schoch KM, von Reyn CR, Bian J, Telling GC, Meaney DF, Saatman KE.

J Neurochem. 2013 Jun;125(6):909-20. doi: 10.1111/jnc.12144. Epub 2013 Feb 3.

33.

Antagonism of purinergic signalling improves recovery from traumatic brain injury.

Choo AM, Miller WJ, Chen YC, Nibley P, Patel TP, Goletiani C, Morrison B 3rd, Kutzing MK, Firestein BL, Sul JY, Haydon PG, Meaney DF.

Brain. 2013 Jan;136(Pt 1):65-80. doi: 10.1093/brain/aws286. Epub 2013 Jan 4.

34.

A Multiscale Approach to Blast Neurotrauma Modeling: Part I - Development of Novel Test Devices for in vivo and in vitro Blast Injury Models.

Panzer MB, Matthews KA, Yu AW, Morrison B 3rd, Meaney DF, Bass CR.

Front Neurol. 2012 Mar 28;3:46. doi: 10.3389/fneur.2012.00046. eCollection 2012.

35.

In vitro stretch injury induces time- and severity-dependent alterations of STEP phosphorylation and proteolysis in neurons.

Mesfin MN, von Reyn CR, Mott RE, Putt ME, Meaney DF.

J Neurotrauma. 2012 Jul 1;29(10):1982-98. doi: 10.1089/neu.2011.2253. Epub 2012 Jun 25.

36.

Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury.

von Reyn CR, Mott RE, Siman R, Smith DH, Meaney DF.

J Neurochem. 2012 Jun;121(5):793-805. doi: 10.1111/j.1471-4159.2012.07735.x. Epub 2012 Apr 12.

37.

NMDA receptor mediated phosphorylation of GluR1 subunits contributes to the appearance of calcium-permeable AMPA receptors after mechanical stretch injury.

Spaethling J, Le L, Meaney DF.

Neurobiol Dis. 2012 Jun;46(3):646-54. doi: 10.1016/j.nbd.2012.03.003. Epub 2012 Mar 9.

38.

A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models.

Effgen GB, Hue CD, Vogel E 3rd, Panzer MB, Meaney DF, Bass CR, Morrison B 3rd.

Front Neurol. 2012 Feb 24;3:23. doi: 10.3389/fneur.2012.00023. eCollection 2012.

39.

NR2A and NR2B subunits differentially mediate MAP kinase signaling and mitochondrial morphology following excitotoxic insult.

Choo AM, Geddes-Klein DM, Hockenberry A, Scarsella D, Mesfin MN, Singh P, Patel TP, Meaney DF.

Neurochem Int. 2012 Apr;60(5):506-16. doi: 10.1016/j.neuint.2012.02.007. Epub 2012 Feb 15.

40.

N-methyl-D-aspartate receptor mechanosensitivity is governed by C terminus of NR2B subunit.

Singh P, Doshi S, Spaethling JM, Hockenberry AJ, Patel TP, Geddes-Klein DM, Lynch DR, Meaney DF.

J Biol Chem. 2012 Feb 3;287(6):4348-59. doi: 10.1074/jbc.M111.253740. Epub 2011 Dec 16.

41.

Perspectives on the role of bioengineering in neurotrauma research.

LaPlaca MC, Meaney DF.

J Neurotrauma. 2011 Nov;28(11):2201-2. doi: 10.1089/neu.2011.9944. No abstract available.

PMID:
22082448
42.

Short-duration treatment with the calpain inhibitor MDL-28170 does not protect axonal transport in an in vivo model of traumatic axonal injury.

Ma M, Li L, Wang X, Bull DL, Shofer FS, Meaney DF, Neumar RW.

J Neurotrauma. 2012 Jan 20;29(2):445-51. doi: 10.1089/neu.2011.2060. Epub 2012 Jan 6.

43.

Dynamic changes in neural circuit topology following mild mechanical injury in vitro.

Patel TP, Ventre SC, Meaney DF.

Ann Biomed Eng. 2012 Jan;40(1):23-36. doi: 10.1007/s10439-011-0390-6. Epub 2011 Oct 13.

44.

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death.

Volpicelli-Daley LA, Luk KC, Patel TP, Tanik SA, Riddle DM, Stieber A, Meaney DF, Trojanowski JQ, Lee VM.

Neuron. 2011 Oct 6;72(1):57-71. doi: 10.1016/j.neuron.2011.08.033.

45.

Mitochondrial injury after mechanical stretch of cortical neurons in vitro: biomarkers of apoptosis and selective peroxidation of anionic phospholipids.

Ji J, Tyurina YY, Tang M, Feng W, Stolz DB, Clark RS, Meaney DF, Kochanek PM, Kagan VE, Bayır H.

J Neurotrauma. 2012 Mar 20;29(5):776-88. doi: 10.1089/neu.2010.1602. Epub 2011 Nov 4.

46.

Mild traumatic brain injury and diffuse axonal injury in swine.

Browne KD, Chen XH, Meaney DF, Smith DH.

J Neurotrauma. 2011 Sep;28(9):1747-55. doi: 10.1089/neu.2011.1913. Epub 2011 Sep 6.

47.

Computational investigation of the changing patterns of subtype specific NMDA receptor activation during physiological glutamatergic neurotransmission.

Singh P, Hockenberry AJ, Tiruvadi VR, Meaney DF.

PLoS Comput Biol. 2011 Jun;7(6):e1002106. doi: 10.1371/journal.pcbi.1002106. Epub 2011 Jun 30.

48.

Biomechanics of concussion.

Meaney DF, Smith DH.

Clin Sports Med. 2011 Jan;30(1):19-31, vii. doi: 10.1016/j.csm.2010.08.009. Review.

49.

Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit.

von Reyn CR, Spaethling JM, Mesfin MN, Ma M, Neumar RW, Smith DH, Siman R, Meaney DF.

J Neurosci. 2009 Aug 19;29(33):10350-6. doi: 10.1523/JNEUROSCI.2339-09.2009.

50.

In-vitro approaches for studying blast-induced traumatic brain injury.

Chen YC, Smith DH, Meaney DF.

J Neurotrauma. 2009 Jun;26(6):861-76. doi: 10.1089/neu.2008.0645. Review.

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