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Items: 1 to 50 of 181

1.

Downregulated AKT-mTOR signaling pathway proteins in dorsolateral prefrontal cortex in Schizophrenia.

Chadha R, Meador-Woodruff JH.

Neuropsychopharmacology. 2020 Jan 17. doi: 10.1038/s41386-020-0614-2. [Epub ahead of print]

PMID:
31952070
2.

Dysregulation of the unfolded protein response (UPR) in the dorsolateral prefrontal cortex in elderly patients with schizophrenia.

Kim P, Scott MR, Meador-Woodruff JH.

Mol Psychiatry. 2019 Oct 2. doi: 10.1038/s41380-019-0537-7. [Epub ahead of print]

PMID:
31578497
3.

Kinase network dysregulation in a human induced pluripotent stem cell model of DISC1 schizophrenia.

Bentea E, Depasquale EAK, O'Donovan SM, Sullivan CR, Simmons M, Meador-Woodruff JH, Zhou Y, Xu C, Bai B, Peng J, Song H, Ming GL, Meller J, Wen Z, McCullumsmith RE.

Mol Omics. 2019 Jun 10;15(3):173-188. doi: 10.1039/c8mo00173a.

4.

Fractionation of Subcellular Compartments from Human Brain Tissue.

Mueller TM, Kim P, Meador-Woodruff JH.

Methods Mol Biol. 2019;1941:201-223. doi: 10.1007/978-1-4939-9077-1_14.

PMID:
30707436
5.

Intracellular compartment-specific proteasome dysfunction in postmortem cortex in schizophrenia subjects.

Scott MR, Meador-Woodruff JH.

Mol Psychiatry. 2019 Jan 25. doi: 10.1038/s41380-019-0359-7. [Epub ahead of print]

6.
7.

Abnormal expression of ER quality control and ER associated degradation proteins in the dorsolateral prefrontal cortex in schizophrenia.

Kim P, Scott MR, Meador-Woodruff JH.

Schizophr Res. 2018 Jul;197:484-491. doi: 10.1016/j.schres.2018.02.010. Epub 2018 Feb 26.

8.

Actin polymerization is reduced in the anterior cingulate cortex of elderly patients with schizophrenia.

Bhambhvani HP, Mueller TM, Simmons MS, Meador-Woodruff JH.

Transl Psychiatry. 2017 Dec 11;7(12):1278. doi: 10.1038/s41398-017-0045-y.

9.

Abnormalities of signal transduction networks in chronic schizophrenia.

McGuire JL, Depasquale EA, Funk AJ, O'Donnovan SM, Hasselfeld K, Marwaha S, Hammond JH, Hartounian V, Meador-Woodruff JH, Meller J, McCullumsmith RE.

NPJ Schizophr. 2017 Sep 12;3(1):30. doi: 10.1038/s41537-017-0032-6.

10.

Pre-clinical Medical Students as the Primary Longitudinal Provider of Psychiatric Care in the Outpatient Setting: A Novel Training Model.

Martinez JTC Jr, Fargason RE, Meador-Woodruff JH.

Acad Psychiatry. 2017 Aug;41(4):538-541. doi: 10.1007/s40596-016-0659-z. Epub 2017 Jan 31. No abstract available.

PMID:
28144829
11.

Altered fucosyltransferase expression in the superior temporal gyrus of elderly patients with schizophrenia.

Mueller TM, Yates SD, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2017 Apr;182:66-73. doi: 10.1016/j.schres.2016.10.024. Epub 2016 Oct 20.

12.

Shaping plasticity: Alterations in glutamate transporter localization as a pathophysiological mechanism in severe mental illness.

McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH.

Mol Psychiatry. 2016 Jun;21(6):723. doi: 10.1038/mp.2016.79. No abstract available.

PMID:
27198660
13.

Decreased protein S-palmitoylation in dorsolateral prefrontal cortex in schizophrenia.

Pinner AL, Tucholski J, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH.

Schizophr Res. 2016 Nov;177(1-3):78-87. doi: 10.1016/j.schres.2016.01.054. Epub 2016 Feb 11.

14.

Decreased expression of cortactin in the schizophrenia brain.

Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH.

Neuroreport. 2016 Feb 10;27(3):145-50. doi: 10.1097/WNR.0000000000000514.

15.

Cortical PGC-1α-Dependent Transcripts Are Reduced in Postmortem Tissue From Patients With Schizophrenia.

McMeekin LJ, Lucas EK, Meador-Woodruff JH, McCullumsmith RE, Hendrickson RC, Gamble KL, Cowell RM.

Schizophr Bull. 2016 Jul;42(4):1009-17. doi: 10.1093/schbul/sbv184. Epub 2015 Dec 17.

16.

Cell-specific abnormalities of glutamate transporters in schizophrenia: sick astrocytes and compensating relay neurons?

McCullumsmith RE, O'Donovan SM, Drummond JB, Benesh FS, Simmons M, Roberts R, Lauriat T, Haroutunian V, Meador-Woodruff JH.

Mol Psychiatry. 2016 Jun;21(6):823-30. doi: 10.1038/mp.2015.148. Epub 2015 Sep 29.

PMID:
26416546
17.

Abnormal subcellular localization of GABAA receptor subunits in schizophrenia brain.

Mueller TM, Remedies CE, Haroutunian V, Meador-Woodruff JH.

Transl Psychiatry. 2015 Aug 4;5:e612. doi: 10.1038/tp.2015.102.

18.

Protein Expression of Proteasome Subunits in Elderly Patients with Schizophrenia.

Scott MR, Rubio MD, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2016 Feb;41(3):896-905. doi: 10.1038/npp.2015.219. Epub 2015 Jul 23.

19.

Abnormal N-acetylglucosaminyltransferase expression in prefrontal cortex in schizophrenia.

Kippe JM, Mueller TM, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2015 Aug;166(1-3):219-24. doi: 10.1016/j.schres.2015.06.002. Epub 2015 Jun 20.

20.

Glutamate transporter splice variant expression in an enriched pyramidal cell population in schizophrenia.

O'Donovan SM, Hasselfeld K, Bauer D, Simmons M, Roussos P, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Transl Psychiatry. 2015 Jun 9;5:e579. doi: 10.1038/tp.2015.74.

21.

Postmortem brain: an underutilized substrate for studying severe mental illness.

McCullumsmith RE, Hammond JH, Shan D, Meador-Woodruff JH.

Neuropsychopharmacology. 2015 Mar 13;40(5):1307. doi: 10.1038/npp.2014.337. No abstract available.

22.

Increased G protein-coupled receptor kinase (GRK) expression in the anterior cingulate cortex in schizophrenia.

Funk AJ, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2014 Oct;159(1):130-5. doi: 10.1016/j.schres.2014.07.040. Epub 2014 Aug 19.

23.

Altered serine/threonine kinase activity in schizophrenia.

McGuire JL, Hammond JH, Yates SD, Chen D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Brain Res. 2014 Jun 3;1568:42-54. doi: 10.1016/j.brainres.2014.04.029. Epub 2014 Apr 26.

24.

Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.

Tucholski J, Pinner AL, Simmons MS, Meador-Woodruff JH.

PLoS One. 2014 Apr 8;9(4):e94255. doi: 10.1371/journal.pone.0094255. eCollection 2014.

25.

Alterations of the myristoylated, alanine-rich C kinase substrate (MARCKS) in prefrontal cortex in schizophrenia.

Pinner AL, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2014 Apr;154(1-3):36-41. doi: 10.1016/j.schres.2014.02.003. Epub 2014 Feb 22.

26.

Abnormal partitioning of hexokinase 1 suggests disruption of a glutamate transport protein complex in schizophrenia.

Shan D, Mount D, Moore S, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2014 Apr;154(1-3):1-13. doi: 10.1016/j.schres.2014.01.028. Epub 2014 Feb 21.

27.

Postmortem brain: an underutilized substrate for studying severe mental illness.

McCullumsmith RE, Hammond JH, Shan D, Meador-Woodruff JH.

Neuropsychopharmacology. 2014 Jan;39(1):65-87. doi: 10.1038/npp.2013.239. Epub 2013 Oct 4. Review. Erratum in: Neuropsychopharmacology. 2015 Apr;40(5):1307.

28.

N-Glycosylation of GABAA receptor subunits is altered in Schizophrenia.

Mueller TM, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2014 Feb;39(3):528-37. doi: 10.1038/npp.2013.190. Epub 2013 Aug 6.

29.

N-linked glycosylation of cortical N-methyl-D-aspartate and kainate receptor subunits in schizophrenia.

Tucholski J, Simmons MS, Pinner AL, McMillan LD, Haroutunian V, Meador-Woodruff JH.

Neuroreport. 2013 Aug 21;24(12):688-91. doi: 10.1097/WNR.0b013e328363bd8a.

30.

Dysfunction of the ubiquitin proteasome and ubiquitin-like systems in schizophrenia.

Rubio MD, Wood K, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2013 Sep;38(10):1910-20. doi: 10.1038/npp.2013.84. Epub 2013 Apr 9.

31.

Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia.

Drummond JB, Tucholski J, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2013 Jun;147(1):32-38. doi: 10.1016/j.schres.2013.03.010. Epub 2013 Apr 6.

32.

Abnormal N-linked glycosylation of cortical AMPA receptor subunits in schizophrenia.

Tucholski J, Simmons MS, Pinner AL, Haroutunian V, McCullumsmith RE, Meador-Woodruff JH.

Schizophr Res. 2013 May;146(1-3):177-83. doi: 10.1016/j.schres.2013.01.031. Epub 2013 Feb 23.

33.

Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy.

Eid T, Lee TS, Wang Y, Perez E, Drummond J, Lauritzen F, Bergersen LH, Meador-Woodruff JH, Spencer DD, de Lanerolle NC, McCullumsmith RE.

Epilepsia. 2013 Feb;54(2):228-38. doi: 10.1111/epi.12008. Epub 2012 Nov 13. Erratum in: Epilepsia. 2013 Jun;54(6):1140. Peréz, Edgar [corrected to Perez, Edgar].

34.

Abnormal expression of glutamate transporters in temporal lobe areas in elderly patients with schizophrenia.

Shan D, Lucas EK, Drummond JB, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2013 Mar;144(1-3):1-8. doi: 10.1016/j.schres.2012.12.019. Epub 2013 Jan 26.

35.

Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia.

Drummond JB, Simmons M, Haroutunian V, Meador-Woodruff JH.

Neuroreport. 2012 Dec 5;23(17):1031-4. doi: 10.1097/WNR.0b013e32835ad229.

PMID:
23103966
36.

AMPA receptor subunit expression in the endoplasmic reticulum in frontal cortex of elderly patients with schizophrenia.

Hammond JC, Meador-Woodruff JH, Haroutunian V, McCullumsmith RE.

PLoS One. 2012;7(6):e39190. doi: 10.1371/journal.pone.0039190. Epub 2012 Jun 14.

37.

Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia.

Rubio MD, Haroutunian V, Meador-Woodruff JH.

Biol Psychiatry. 2012 May 15;71(10):906-14. doi: 10.1016/j.biopsych.2012.02.006. Epub 2012 Mar 27.

38.

Expression of equilibrative nucleoside transporter type 1 protein in elderly patients with schizophrenia.

Shan D, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Neuroreport. 2012 Mar 7;23(4):224-7. doi: 10.1097/WNR.0b013e3283500987.

39.

Recent advances in targeting the ionotropic glutamate receptors in treating schizophrenia.

McCullumsmith RE, Hammond J, Funk A, Meador-Woodruff JH.

Curr Pharm Biotechnol. 2012 Jun;13(8):1535-42. Review.

40.

Regional differences in expression of β-tubulin isoforms in schizophrenia.

Moehle MS, Luduena RF, Haroutunian V, Meador-Woodruff JH, McCullumsmith RE.

Schizophr Res. 2012 Mar;135(1-3):181-6. doi: 10.1016/j.schres.2011.12.010. Epub 2012 Jan 20.

41.

Glutamate receptor abnormalities in schizophrenia: implications for innovative treatments.

Rubio MD, Drummond JB, Meador-Woodruff JH.

Biomol Ther (Seoul). 2012 Jan;20(1):1-18. doi: 10.4062/biomolther.2012.20.1.001. Review.

42.

Abnormal activity of the MAPK- and cAMP-associated signaling pathways in frontal cortical areas in postmortem brain in schizophrenia.

Funk AJ, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2012 Mar;37(4):896-905. doi: 10.1038/npp.2011.267. Epub 2011 Nov 2.

43.

Endosomal trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia.

Hammond JC, McCullumsmith RE, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2011 Aug;130(1-3):260-5. doi: 10.1016/j.schres.2011.04.029. Epub 2011 May 14.

44.

Glutamatergic gene expression is specifically reduced in thalamocortical projecting relay neurons in schizophrenia.

Sodhi MS, Simmons M, McCullumsmith R, Haroutunian V, Meador-Woodruff JH.

Biol Psychiatry. 2011 Oct 1;70(7):646-54. doi: 10.1016/j.biopsych.2011.02.022. Epub 2011 May 6.

45.

Innovative approach to research training: research colloquium for junior investigators.

Balon R, Guerra E, Meador-Woodruff JH, Oquendo MA, Salloum IM, Casiano DE, Nemeroff CB.

Acad Psychiatry. 2011 Jan-Feb;35(1):11-4. doi: 10.1176/appi.ap.35.1.11. No abstract available.

46.

Novel approaches to the study of postmortem brain in psychiatric illness: old limitations and new challenges.

McCullumsmith RE, Meador-Woodruff JH.

Biol Psychiatry. 2011 Jan 15;69(2):127-33. doi: 10.1016/j.biopsych.2010.09.035. Epub 2010 Nov 20. Review.

PMID:
21094488
47.

Increased cortical expression of an RNA editing enzyme occurs in major depressive suicide victims.

Simmons M, Meador-Woodruff JH, Sodhi MS.

Neuroreport. 2010 Oct 27;21(15):993-7. doi: 10.1097/WNR.0b013e32833f11c3.

PMID:
20802353
48.

Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia.

Hammond JC, McCullumsmith RE, Funk AJ, Haroutunian V, Meador-Woodruff JH.

Neuropsychopharmacology. 2010 Sep;35(10):2110-9. doi: 10.1038/npp.2010.87. Epub 2010 Jun 23.

49.

Parvalbumin deficiency and GABAergic dysfunction in mice lacking PGC-1alpha.

Lucas EK, Markwardt SJ, Gupta S, Meador-Woodruff JH, Lin JD, Overstreet-Wadiche L, Cowell RM.

J Neurosci. 2010 May 26;30(21):7227-35. doi: 10.1523/JNEUROSCI.0698-10.2010.

50.

Expression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophrenia.

Kristiansen LV, Bakir B, Haroutunian V, Meador-Woodruff JH.

Schizophr Res. 2010 Jun;119(1-3):198-209. doi: 10.1016/j.schres.2010.02.1069. Epub 2010 Mar 29.

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